Works Published in 2013
Displaying works 21 - 40 of 52 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2013 journal article
Transcriptional analysis of oligosaccharide utilization by Bifidobacterium lactis Bl-04
BMC GENOMICS, 14.
author keywords: Bifidobacterium lactis; Transcriptomics; ABC transporter; GPH transporter; Prebiotics; Glycoside hydrolase
MeSH headings : Bifidobacterium / drug effects; Bifidobacterium / genetics; Cell Membrane / drug effects; Cell Membrane / metabolism; Data Mining; Gene Expression Profiling; Genetic Variation / genetics; Genomics; Multigene Family / genetics; Oligosaccharides / pharmacology; Prebiotics; Transcription, Genetic / drug effects; Up-Regulation / drug effects
TL;DR:
This study identified the differential gene expression for utilization of potential prebiotics highlighting the extensive capabilities of Bifidobacterium lactis Bl-04 to utilize oligosaccharides.
(via Semantic Scholar)
bmcgenomics.biomedcentral.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2013 review
The evolving role of the orphan nuclear receptor ftz-f1, a pair-rule segmentation gene
[Review of ]. EVOLUTION & DEVELOPMENT, 15(6), 406–417.
MeSH headings : Animals; Drosophila melanogaster / metabolism; Evolution, Molecular; Gene Expression Regulation, Developmental; Insect Proteins / chemistry; Insect Proteins / genetics; Insect Proteins / metabolism; Orphan Nuclear Receptors / chemistry; Orphan Nuclear Receptors / genetics; Orphan Nuclear Receptors / metabolism; Tribolium / embryology; Tribolium / genetics; Tribolium / metabolism
TL;DR:
It is proposed that the dependence of Dm‐Ftz‐F1 on interaction with the homeodomain protein Ftz which is expressed in stripes in Drosophila, loosened constraints on DM‐ftz‐f1 expression, allowing for ubiquitous expression of this pair‐rule gene in Dosophila.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Localization, morphology and transcriptional profile of Aspergillus flavus during seed colonization
MOLECULAR PLANT PATHOLOGY, 14(9), 898–909.
MeSH headings : Aspergillus flavus / genetics; Aspergillus flavus / growth & development; Aspergillus flavus / pathogenicity; Chromosomes, Fungal / genetics; Colony Count, Microbial; DNA, Fungal / isolation & purification; Electrophoresis, Agar Gel; Endosperm / microbiology; Gene Expression Profiling; Gene Expression Regulation, Fungal; Genes, Fungal / genetics; Humans; Seeds / cytology; Seeds / microbiology; Transcription Factors / metabolism; Transcription, Genetic; Zea mays / cytology; Zea mays / microbiology
TL;DR:
Results from these studies indicate that A. flavus is capable of infecting all tissues of the immature kernel by 96 h after infection and will aid in the development of strategies aimed at preventing or slowing down A. flavus colonization of the maize kernel.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Genomic architecture of adaptive color pattern divergence and convergence in Heliconius butterflies
GENOME RESEARCH, 23(8), 1248–1257.
MeSH headings : Adaptation, Biological / genetics; Animal Distribution; Animals; Base Sequence; Bayes Theorem; Butterflies / genetics; Conserved Sequence; Evolution, Molecular; Genetic Speciation; Genome, Insect; Genotype; Haplotypes; High-Throughput Nucleotide Sequencing; Likelihood Functions; Models, Genetic; Molecular Sequence Annotation; Molecular Sequence Data; Panama; Phenotype; Phylogeny; Pigmentation / genetics; Sequence Analysis, DNA; South America; Synteny; Transcriptome; Wings, Animal / physiology
TL;DR:
A combination of techniques are used to annotate the genomic interval modulating red color pattern variation, identify a narrow region responsible for adaptive divergence and convergence in Heliconius wing color patterns, and explore the evolutionary history of these adaptive alleles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 review
Genomic and phenotypic evidence for probiotic influences of Lactobacillus gasseri on human health
[Review of ]. FEMS MICROBIOLOGY REVIEWS, 37(6), 915–935.
author keywords: gastrointestinal tract; acidophilus complex; bacteriocin; lactic acid bacteria; autochthonous; microbiota
MeSH headings : Animals; Bacteriocins / metabolism; Female; Gastrointestinal Tract / microbiology; Gastrointestinal Tract / physiology; Genome, Bacterial; Health; Helicobacter Infections / diet therapy; Helicobacter pylori; Homeostasis; Humans; Hypersensitivity / prevention & control; Immune System / physiology; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / physiology; Probiotics / therapeutic use; Vagina / microbiology; Vagina / physiology; Virus Diseases / diet therapy
TL;DR:
The genomic and empirical evidence supporting use of L. gasseri in probiotic applications is substantiated by clinical trial data displaying maintenance of vaginal homeostasis, mitigation of Helicobacter pylori infection, and amelioration of diarrhea.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Fine-scale heterogeneity in crossover rate in the garnet-scalloped region of the Drosophila melanogaster X chromosome
Genetics, 194(2), 375–112.
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
Differentially expressed microRNAs and affected biological pathways revealed by modulated modularity clustering (MMC) analysis of human preeclamptic and IUGR placentas
PLACENTA, 34(7), 599–605.
author keywords: Placenta; Preeclampsia; IUGR; MiR-194; MiR-149
MeSH headings : Down-Regulation; Female; Fetal Growth Retardation / genetics; Fetal Growth Retardation / metabolism; Humans; MicroRNAs / biosynthesis; Placenta / metabolism; Pre-Eclampsia / genetics; Pre-Eclampsia / metabolism; Pregnancy; Transcriptome
TL;DR:
Modulated modularity clustering (MMC) allowed the elucidation of a molecular signature associated with preeclampsia and a subset of IUGR samples, which allowed the identification of genes, pathways, and microRNAs affected in these diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 review
Auxin and the Arabidopsis thaliana gynoecium
[Review of ]. JOURNAL OF EXPERIMENTAL BOTANY, 64(9), 2619–2627.
Contributors: E. Larsson*, R. Franks n & E. Sundberg *
author keywords: Arabidopsis; auxin; development; female reproductive organ; gynoecium; patterning
MeSH headings : Arabidopsis / growth & development; Arabidopsis / metabolism; Arabidopsis Proteins / metabolism; Arabidopsis Proteins / physiology; Flowers / growth & development; Flowers / metabolism; Homeostasis; Indoleacetic Acids / metabolism; Plant Growth Regulators / metabolism
TL;DR:
This review summarizes recent advances in understanding of how auxin biosynthesis, transport, and responses together generate specific gynoecial domains and highlights areas where future research endeavours are likely to provide additional insight into the homeostatic molecular mechanisms by which auxin regulates gynOecium development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 journal article
Sexuality Generates Diversity in the Aflatoxin Gene Cluster: Evidence on a Global Scale
PLOS PATHOGENS, 9(8).
MeSH headings : Aflatoxins / biosynthesis; Aflatoxins / genetics; Aspergillus flavus / genetics; Aspergillus flavus / metabolism; Fungal Proteins / genetics; Fungal Proteins / metabolism; Genes, Fungal / physiology; Multigene Family / physiology; Repressor Proteins / genetics; Repressor Proteins / metabolism; Species Specificity
TL;DR:
It is shown that the reproductive nature of the population (more sexual versus more asexual) is predictive of aflatoxin chemotype diversity in these agriculturally important fungi.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2013 article
Polygenic sex determination
Moore, E. C., & Roberts, R. B. (2013, June 17). CURRENT BIOLOGY, Vol. 23, pp. R510–R512.
MeSH headings : Animals; Female; Male; Multifactorial Inheritance; Sex Chromosomes / genetics; Sex Determination Processes / genetics; Sex Determination Processes / physiology; Signal Transduction
TL;DR:
Sex determination is the mechanism by which sexual organisms direct gonad development towards distinct but reproductively compatible outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Peptide Aptamers That Bind to Geminivirus Replication Proteins Confer a Resistance Phenotype to Tomato Yellow Leaf Curl Virus and Tomato Mottle Virus Infection in Tomato
JOURNAL OF VIROLOGY, 87(17), 9691–9706.
MeSH headings : Amino Acid Sequence; Aptamers, Peptide / genetics; Aptamers, Peptide / metabolism; Begomovirus / genetics; Begomovirus / pathogenicity; Begomovirus / physiology; DNA, Viral / genetics; DNA, Viral / metabolism; Geminiviridae / genetics; Geminiviridae / pathogenicity; Geminiviridae / physiology; Solanum lycopersicum / virology; Molecular Sequence Data; Phenotype; Plant Diseases / genetics; Plant Diseases / prevention & control; Plant Diseases / virology; Plants, Genetically Modified; Protein Binding; Two-Hybrid System Techniques; Viral Proteins / genetics; Viral Proteins / physiology; Virus Replication
TL;DR:
The efficacy of using Rep-binding peptide aptamers to develop crops that are resistant to diverse geminiviruses is established.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL
CANCER RESEARCH, 73(16), 5029–5039.
MeSH headings : Adolescent; Animals; Child; Child, Preschool; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Disease Models, Animal; Dogs; Female; Gene Expression Profiling / methods; Germinal Center / metabolism; Germinal Center / pathology; Humans; Immunoglobulin Heavy Chains / genetics; Immunoglobulin Heavy Chains / metabolism; Interferon Regulatory Factors / genetics; Interferon Regulatory Factors / metabolism; Lymph Nodes / metabolism; Lymph Nodes / pathology; Lymphoma, B-Cell / genetics; Lymphoma, B-Cell / metabolism; Lymphoma, B-Cell / pathology; Lymphoma, Large B-Cell, Diffuse / genetics; Lymphoma, Large B-Cell, Diffuse / metabolism; Lymphoma, Large B-Cell, Diffuse / pathology; Male; Mutation; NF-kappa B / genetics; NF-kappa B / metabolism; Proto-Oncogene Proteins c-bcl-6; Transcriptome
TL;DR:
These studies identify molecular similarities to h DLBCL that introduce pet dogs as a representative model of hDLBCL for future studies, including therapeutic clinical trials.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 review
Microbial interactions in food fermentations
[Review of ]. Annual review of food science and technology, vol 4, 4, 141–162.
Source: NC State University Libraries
Added: August 6, 2018
2013 review
Geminiviruses: masters at redirecting and reprogramming plant processes
[Review of ]. NATURE REVIEWS MICROBIOLOGY, 11(11), 777–788.
MeSH headings : Geminiviridae / physiology; Gene Expression Regulation, Viral / physiology; Genome, Viral; Host-Pathogen Interactions; Plant Diseases / virology; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR:
This Review describes the current knowledge of how geminiviruses interact with their plant hosts and the functional consequences of these interactions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science; OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
A functional glycogen biosynthesis pathway in Lactobacillus acidophilus: expression and analysis of the glg operon
MOLECULAR MICROBIOLOGY, 89(6), 1187–1200.
MeSH headings : 1,4-alpha-Glucan Branching Enzyme / genetics; 1,4-alpha-Glucan Branching Enzyme / metabolism; Bile / metabolism; Biosynthetic Pathways / genetics; Carbon / metabolism; Energy Metabolism; Gene Deletion; Gene Expression Regulation, Bacterial; Glucose / metabolism; Glycogen / biosynthesis; Glycogen Phosphorylase / genetics; Glycogen Phosphorylase / metabolism; Glycogen Synthase / genetics; Glycogen Synthase / metabolism; Humans; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / growth & development; Lactobacillus acidophilus / metabolism; Operon; Raffinose / metabolism; Trehalose / metabolism
TL;DR:
The data indicate that glycogen metabolism is involved in growth maintenance, bile tolerance and complex carbohydrate utilization in L. acidophilus, a probiotic microbe in the human gastrointestinal environment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
The genetic architecture of maize stalk strength
PLoS One, 8(6).
Source: NC State University Libraries
Added: August 6, 2018
2013 review
Recent insight into oligosaccharide uptake and metabolism in probiotic bacteria
[Review of ]. BIOCATALYSIS AND BIOTRANSFORMATION, 31(4), 226–235.
author keywords: Prebiotic; oligosaccharide uptake; ATP-binding cassette transport system; phosphotransferase system; transcriptional analysis
TL;DR:
It is demonstrated for the first time that non-naturally occurring tri- and tetra-saccharides are internalized and efficiently utilized by probiotic bacteria in some cases better than well-established natural prebiotics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
10. Reduced Inequalities
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Modeling Host Genetic Regulation of Influenza Pathogenesis in the Collaborative Cross
PLOS PATHOGENS, 9(2).
MeSH headings : Animals; Crosses, Genetic; Female; Genetic Variation; Host-Pathogen Interactions / genetics; Humans; Influenza A virus; Influenza, Human / genetics; Influenza, Human / pathology; Influenza, Human / virology; Lung / pathology; Mice; Mice, Inbred Strains; Models, Genetic; Orthomyxoviridae Infections / genetics; Orthomyxoviridae Infections / pathology; Orthomyxoviridae Infections / virology; Phenotype; Reassortant Viruses / genetics; Reassortant Viruses / pathogenicity; Recombination, Genetic; Rodent Diseases / genetics; Rodent Diseases / pathology; Rodent Diseases / virology; Species Specificity; Virus Replication
TL;DR:
To identify how host genetic polymorphisms contribute to the observed variation in disease, quantitative trait loci (QTL) mapping was conducted and several QTL contributing to specific aspects of the host response including virus-induced weight loss, titer, pulmonary edema, neutrophil recruitment to the airways, and transcriptional expression were identified.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Knockdown of CDKN1C (p57(kip2)) and PHLDA2 results in developmental changes in bovine pre-implantation embryos
PLoS One, 8(7).
Source: NC State University Libraries
Added: August 6, 2018
2013 review
A molecular mechanism for glaucoma: endoplasmic reticulum stress and the unfolded protein response
[Review of ]. TRENDS IN MOLECULAR MEDICINE, 19(10), 586–593.
author keywords: primary open angle glaucoma; ocular hypertension; myocilin; neurodegenerative disease
MeSH headings : Animals; Cytoskeletal Proteins / metabolism; Endoplasmic Reticulum Stress; Eye Proteins / metabolism; Glaucoma / pathology; Glycoproteins / metabolism; Humans; Neurodegenerative Diseases / pathology; Translational Research, Biomedical; Unfolded Protein Response
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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