Works Published in 2018
Displaying works 21 - 36 of 36 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2018 journal article
Active Tara Gum/PVA Blend Films with Curcumin-Loaded CTAC Brush-TEMPO-Oxidized Cellulose Nanocrystals
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 6(7), 8926–8934.
author keywords: Active films; Tara gum; TEMPO; Cellulose nanocrystals; Curcumin
TL;DR:
Active films containing curcumin exhibit outstanding antioxidant and antibacterial properties and DPPH and ABTS+ assays were used to measure the antioxidation properties.
(via Semantic Scholar)
Source: Web Of Science
Added: October 16, 2018
2018 journal article
Microinjection of Western Corn Rootworm, Diabrotica virgifera virgifera, Embryos for Germline Transformation, or CRISPR/Cas9 Genome Editing
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (134).
author keywords: Bioengineering; Issue 134; embryonic microinjection; functional genomics; germline transformation; transgenesis; CRISPR/Cas9 genome editing; western corn rootworm
MeSH headings : Animals; CRISPR-Cas Systems / genetics; Coleoptera; Gene Editing / methods; Germ-Line Mutation / genetics; Microinjections / methods; RNA Interference
TL;DR:
The methods used to collect and microinject precellular WCR embryos with nucleic acids are detailed, aimed at the creation of transgenic WCR, and CRISPR/Cas9-genome editing could also be performed using the same protocols, with the only difference being the composition of the solution injected into the embryos.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: October 16, 2018
2018 journal article
no blokes Is Essential for Male Viability and X Chromosome Gene Expression in the Australian Sheep Blowfly
Current Biology, 28(12), 1987–1992.e3.
MeSH headings : Animals; Diptera / genetics; Diptera / physiology; Dosage Compensation, Genetic / genetics; Female; Gene Expression; Genes, Insect / genetics; Genes, X-Linked / genetics; Male; X Chromosome / genetics
TL;DR:
This study supports the hypothesis on the origin of the Drosophila 4th chromosome and that a POF-like protein was required for normal gene expression on the ancient X chromosome and suggests that NBL could be important for X chromosome dosage compensation in L. cuprina.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2018 journal article
Nod2 is required for antigen-specific humoral responses against antigens orally delivered using a recombinant Lactobacillus vaccine platform
PLOS ONE, 13(5).
MeSH headings : Administration, Oral; Animals; Antigens / administration & dosage; Caspase 1 / genetics; Caspase 1 / immunology; Genes, gag / genetics; HIV-1 / immunology; HIV-1 / pathogenicity; Humans; Immunity, Humoral / genetics; Immunity, Humoral / immunology; Inflammasomes / genetics; Inflammasomes / immunology; Interleukin-1beta / genetics; Interleukin-1beta / immunology; Lactobacillus acidophilus / immunology; Lipopolysaccharides / immunology; Lipopolysaccharides / metabolism; Macrophages / immunology; Macrophages / microbiology; Mice; Nod2 Signaling Adaptor Protein / genetics; Nod2 Signaling Adaptor Protein / immunology; Teichoic Acids / immunology; Teichoic Acids / metabolism; Toll-Like Receptor 2 / genetics; Toll-Like Receptor 2 / immunology; Vaccines / administration & dosage; Vaccines / immunology
TL;DR:
It is demonstrated that NOD2 signaling is required for antigen-specific mucosal and systemic humoral responses to a NCFM-based mucosal vaccine platform with surface expression of human immunodeficiency virus type 1 (HIV-1) Gag or membrane proximal external region (MPER).
(via Semantic Scholar)
journals.plos.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Effect of genetic architecture on the prediction accuracy of quantitative traits in samples of unrelated individuals
HEREDITY, 120(6), 500–514.
MeSH headings : Algorithms; Alleles; Animals; Computer Simulation; Data Interpretation, Statistical; Databases, Genetic; Drosophila melanogaster / genetics; Epistasis, Genetic; Gene Frequency; Genetic Association Studies; Genetic Variation; Genetics, Population; Genome-Wide Association Study / methods; Genotype; Linkage Disequilibrium; Models, Genetic; Quantitative Trait Loci; Quantitative Trait, Heritable; Reproducibility of Results
TL;DR:
The results indicate that accounting for genetic architecture can improve prediction accuracy for quantitative traits, especially when predictions are informed by the genetic architecture inferred from mapping the top variants affecting main effects and interactions in the training data, provided there is sufficient power for mapping.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Towards next generation maggot debridement therapy: Transgenic Lucilia sericata larvae that produce and secrete a human growth factor
Wound Repair and Regeneration, 26(1), A27–27.
Source: NC State University Libraries
Added: August 6, 2018
2018 journal article
Supplementation of Maternal Diets with Docosahexaenoic Acid and Methylating Vitamins Impacts Growth and Development of Fetuses from Malnourished Gilts
CURRENT DEVELOPMENTS IN NUTRITION, 2(3).
author keywords: choline; B-vitamins; epigenetics; intrauterine growth restriction; nutrient restriction; low birth weight
TL;DR:
Despite the mobilization of maternal stores, malnourished litters displayed reduced brain development that was fully mitigated by micronutrient supplementation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Phenotypic and genotypic diversity of Lactobacillus buchneri strains isolated from spoiled, fermented cucumber
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 280, 46–56.
author keywords: Lactic acid bacteria; Pickled vegetables; Spoilage organisms; Lactobacillus buchneri; Strain diversity
MeSH headings : Acetic Acid / metabolism; Bioreactors; Cucumis sativus / microbiology; Fermentation; Genotype; Lactic Acid / metabolism; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / isolation & purification; Lactobacillus / metabolism; Propylene Glycol / metabolism; RNA, Ribosomal, 16S / genetics
TL;DR:
Describing isolates of L. buchneri purified from both industrial and experimental fermented cucumber after the onset of secondary fermentation provided the basis for further analysis of metabolic and genomic capabilities of this species to enable control of lactic acid degradation in fermented plant materials.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
High mobility group A2 (HMGA2) deficiency in pigs leads to dwarfism, abnormal fetal resource allocation, and cryptorchidism
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(21), 5420–5425.
author keywords: HMGA2; dwarfism; swine; gene editing; organ size
MeSH headings : Animals; Cryptorchidism / etiology; Cryptorchidism / pathology; Dwarfism / etiology; Dwarfism / pathology; Female; Fetal Diseases / etiology; Fetal Diseases / pathology; Genotype; HMGA2 Protein / deficiency; HMGA2 Protein / genetics; Litter Size; Male; Nuclear Transfer Techniques / veterinary; Pregnancy; Reproduction; Swine; Swine Diseases / etiology; Swine Diseases / pathology
TL;DR:
The results show that the effect of HMGA2 with respect to growth regulation is highly conserved among mammals and opens up the possibility of regulating body and organ size in a variety of mammalian species including food and companion animals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 review
A Plant Biologist's Toolbox to Study Translation
[Review of ]. FRONTIERS IN PLANT SCIENCE, 9.
Contributors: S. Mazzoni-Putman n & A. Stepanova n
author keywords: translation; ribosome; Ribo-seq; TRAP; polysome profiling; toeprinting; reporter; amino acid tagging
TL;DR:
A review of translational methods in plant biology covering a broad range of methods to measure changes in global translation, with a particular note of how applications from other model systems might be extended for use in plants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2018 journal article
Lanai: A small, fast growing tomato variety is an excellent model system for studying geminiviruses
JOURNAL OF VIROLOGICAL METHODS, 256, 89–99.
author keywords: Florida lanai; Tomato; Geminiviruses; Symptoms; qPCR; Ploidy; Seed transmission
MeSH headings : Analysis of Variance; Geminiviridae / genetics; Genome, Viral; Solanum lycopersicum / virology; Phenotype; Plant Diseases / virology; Ploidies
TL;DR:
Florida Lanai is a tomato variety suitable for virus-host interaction studies and an excellent choice for comparing geminivirus infections.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Agricultural production: assessment of the potential use of Cas9-mediated gene drive systems for agricultural pest control
JOURNAL OF RESPONSIBLE INNOVATION, 5(sup1), S98–S120.
author keywords: Gene drive; Cas9; sterile insect technique; agricultural pest insect
TL;DR:
To highlight how gene drives could be useful for control of agricultural insect pests, species that are pests of animals, plants, and animals are selected.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Development and use of a piggyBac-based jumpstarter system in Drosophila suzukii
ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY, 97(3).
author keywords: germline transformation; Minos; mutagenesis; piggyBac; transgenesis
MeSH headings : Animals; Animals, Genetically Modified; DNA Transposable Elements; Drosophila / genetics; Genetic Engineering / methods; Mutagenesis; Transposases
TL;DR:
It is demonstrated that there is a dramatic increase in transformation rates when germline transformation is performed in a transposase-expressing background, and it is shown that these jumpstarter strains could be used in conjunction with a piggyBac-based donor strain for genome-wide mutagenesis of D. suzukii.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Genome-Wide Analysis of the Arabidopsis Replication Timing Program
PLANT PHYSIOLOGY, 176(3), 2166–2185.
MeSH headings : Arabidopsis / genetics; Chromatin / genetics; Chromatin / metabolism; Chromosomes, Plant; DNA Replication Timing; DNA Transposable Elements; Flow Cytometry; Genome, Plant; Genome-Wide Association Study; S Phase / genetics; Sequence Analysis, DNA / methods
TL;DR:
The thymidine analog, 5-ethynyl-2′-deoxyuridine, is used in combination with flow sorting and Repli-Seq to describe the genome-wide replication timing program for Arabidopsis (Arabidopsis thaliana) Col-0 suspension cells, and genomic regions that replicate predominantly during early, mid, and late S phase are identified.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Evaluation of genes associated with human myxomatous mitral valve disease in dogs with familial myxomatous mitral valve degeneration
VETERINARY JOURNAL, 232, 16–19.
author keywords: Canine; Cavalier King Charles spaniel; Dachshund; Genetic; Mitral valve; Myxomatous valve
MeSH headings : Animals; DNA / blood; Dog Diseases / genetics; Dogs; Heart Valve Diseases / genetics; Heart Valve Diseases / veterinary; Humans; Mitral Valve; Mitral Valve Prolapse / genetics; Mutation; Species Specificity; Whole Genome Sequencing / veterinary
TL;DR:
Although mitral valve disease in the CKCS and Dachshund is a familial disease, it was hypothesized that a genetic mutation associated with the development of the human form of MMVD was associated withthe development of canine MMVD and this work identified genetic cause in the genes responsible for the human disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Estimating Realized Heritability in Panmictic Populations
GENETICS, 208(1), 89–95.
author keywords: quantitative genetics; Hardy-Weinberg equilibrium; panmictic population
MeSH headings : Algorithms; Body Height; Computer Simulation; Genetics, Population; Humans; Inheritance Patterns; Models, Genetic; Pedigree; Phenotype; Quantitative Trait, Heritable; Selection, Genetic
TL;DR:
This work presents a method for estimating realized h2 based on a simple assessment of a random-mating population with no artificial manipulation of the population structure, and derives unbiased estimates of h2 from the mathematical derivation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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