Works Published in 2011
Displaying works 61 - 71 of 71 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
High-Confidence Discovery of Genetic Network Regulators in Expression Quantitative Trait Loci Data
GENETICS, 187(3), 955–964.
MeSH headings : Algorithms; Bayes Theorem; Chromosome Mapping; Computational Biology; Computer Simulation; Gene Expression Profiling / statistics & numerical data; Gene Regulatory Networks; Genes, Regulator / genetics; Genetic Markers / genetics; Models, Genetic; Quantitative Trait Loci / genetics; Saccharomyces cerevisiae / genetics
TL;DR:
This work introduces the concept of “shielding” in which a specific gene expression variable (the shielder) renders a set of other gene expression variables (the shielded genes) independent of the eQTL, and proposes a novel test for controlling the shielder false-positive rate at a predetermined level by requiring a threshold number of shielded genes per shielder.
(via Semantic Scholar)
www.genetics.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 article
A rendezvous with our microbes
Gordon, J. I., & Klaenhammer, T. R. (2011, March 15). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 108, pp. 4513–4515.
MeSH headings : Bacteria; Biological Evolution; Humans; Microbiology / trends; Symbiosis
TL;DR:
On November 2–3, 2009 an international group of scientists representing multiple disciplines gathered to consider the current state of the authors' understanding of the symbiotic and beneficial relationships between microbes and humans and to define the challenges, gaps in knowledge, and opportunities that this exciting field of study now offers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Interstrain Differences in the Liver Effects of Trichloroethylene in a Multistrain Panel of Inbred Mice
TOXICOLOGICAL SCIENCES, 120(1), 206–217.
author keywords: trichloroethylene; metabolism; genetics; peroxisome proliferator-activated receptor alpha; acute exposure; gene expression
MeSH headings : Animals; Environmental Pollutants / blood; Environmental Pollutants / metabolism; Environmental Pollutants / toxicity; Gene Expression / drug effects; Gene Expression Profiling; Liver / drug effects; Liver / metabolism; Liver / pathology; Male; Mice; Mice, Inbred Strains; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Trichloroethylene / blood; Trichloroethylene / metabolism; Trichloroethylene / toxicity
TL;DR:
These studies provide better understanding of the mechanisms of TCE-induced toxicity anchored on metabolism and genotype-phenotype correlations that may define susceptibility or resistance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Epiregulin-dependent amphiregulin expression and ERBB2 signaling are involved in luteinizing hormone-induced paracrine signaling pathways in mouse ovary
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 405(2), 319–324.
author keywords: Amphiregulin; Epiregulin; EGFR and ERBB2 phosphorylation; Oocyte maturation; Ovulation
MeSH headings : Amphiregulin; Animals; EGF Family of Proteins; Epidermal Growth Factor / genetics; Epidermal Growth Factor / metabolism; Epiregulin; ErbB Receptors / metabolism; Female; Glycoproteins / biosynthesis; Glycoproteins / genetics; Intercellular Signaling Peptides and Proteins / biosynthesis; Intercellular Signaling Peptides and Proteins / genetics; Luteinizing Hormone / metabolism; Meiosis; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Ovary / cytology; Ovary / metabolism; Ovary / physiology; Ovulation; Phosphorylation; RNA, Messenger / biosynthesis; Receptor, ErbB-2 / metabolism; Signal Transduction
TL;DR:
This study implicates that EREG mediates signals downstream of Areg mRNA expression and that EGFR-ERBB2 signals contributes to regulation of ovulation process.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
A population genetic approach to mapping neurological disorder genes using deep resequencing
PLoS Genetics, 7(2).
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Organisation and expression of a cluster of yolk protein genes in the Australian sheep blowfly, Lucilia cuprina
GENETICA, 139(1), 63–70.
author keywords: Yolk protein; Sterile insect technique; Lucilia cuprina
MeSH headings : Amino Acid Sequence; Animals; Animals, Genetically Modified / genetics; Australia; Diptera / genetics; Egg Proteins / genetics; Female; Gene Expression Regulation; Genes, Insect; Genetic Vectors; Germ Cells; Male; Molecular Sequence Data; Multigene Family; New Zealand; Sheep / parasitology; Transformation, Genetic; Transgenes
TL;DR:
The sequence of a 14.2 kb genomic clone from L. cuprina that contains a cluster of three complete yp genes and one partial yp gene is reported, suggesting the LcypA promoter could be used to obtain female-specific expression of tTA in transgenic L.cuprina.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
Glycine and a Glycine Dehydrogenase (GLDC) SNP as Citalopram/Escitalopram Response Biomarkers in Depression: Pharmacometabolomics-Informed Pharmacogenomics
CLINICAL PHARMACOLOGY & THERAPEUTICS, 89(1), 97–104.
MeSH headings : Biomarkers, Pharmacological / blood; Cell Line; Chromosomes, Human, Pair 9 / genetics; Citalopram / therapeutic use; DNA-Binding Proteins / metabolism; Depressive Disorder, Major / blood; Depressive Disorder, Major / drug therapy; Depressive Disorder, Major / genetics; Drug Monitoring / methods; Female; Genetic Association Studies; Glycine / blood; Glycine / metabolism; Glycine Dehydrogenase (Decarboxylating) / genetics; Humans; Introns / genetics; Linkage Disequilibrium; Male; Metabolome / drug effects; Nuclear Proteins / metabolism; Polymorphism, Single Nucleotide; Selective Serotonin Reuptake Inhibitors / therapeutic use
TL;DR:
A possible role for glycine in SSRI response is highlighted and the use of pharmacometabolomics‐informed pharmacogenomic research strategy to identify citalopram/escitaloprams treatment outcome biomarkers is illustrated to “inform” pharmacogenomics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Genome-wide association study of leaf architecture in the maize nested association mapping population
NATURE GENETICS, 43(2), 159–U113.
MeSH headings : Chromosome Mapping; Chromosomes, Plant; Epistasis, Genetic; Genes, Plant; Genetic Linkage; Genetic Variation; Genome-Wide Association Study; Plant Leaves / metabolism; Quantitative Trait Loci; Zea mays / genetics
TL;DR:
Overall, GWAS results show that variations at the liguleless genes have contributed to more upright leaves, and the use of GWAS with specially designed mapping populations is effective in uncovering the basis of key agronomic traits.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Fur Negatively Regulates hns and Is Required for the Expression of HilA and Virulence in Salmonella enterica Serovar Typhimurium
JOURNAL OF BACTERIOLOGY, 193(2), 497–505.
MeSH headings : Animals; Bacterial Proteins / biosynthesis; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Chromatin Immunoprecipitation; DNA, Bacterial / metabolism; DNA-Binding Proteins / biosynthesis; DNA-Binding Proteins / metabolism; Disease Models, Animal; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Genes, Bacterial; Genomic Islands; Mice; Mice, Inbred C3H; Operon; Protein Binding; Repressor Proteins / genetics; Repressor Proteins / metabolism; Salmonella Infections, Animal / microbiology; Salmonella typhimurium / pathogenicity; Salmonella typhimurium / physiology; Survival Analysis; Trans-Activators / biosynthesis; Transcription Factors / biosynthesis; Virulence; Virulence Factors / biosynthesis
TL;DR:
Fur is required for virulence in Salmonella enterica serovar Typhimurium and that Fur is necessary for the activation of hilA, as well as of other HilA-dependent genes, invF and sipC, and chromatin immunoprecipitation was used to show that Fur bound to the upstream region of hns in a metal-dependent fashion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Functional Analysis of a Novel Motif Conserved across Geminivirus Rep Proteins
JOURNAL OF VIROLOGY, 85(3), 1182–1192.
MeSH headings : Amino Acid Motifs; Amino Acid Sequence; Conserved Sequence; DNA Helicases / genetics; DNA Helicases / metabolism; DNA, Viral / metabolism; Geminiviridae / enzymology; Geminiviridae / genetics; Geminiviridae / physiology; Molecular Sequence Data; Mutation, Missense; Plant Diseases / virology; Protein Binding; Sequence Alignment; Tobacco / virology; Trans-Activators / genetics; Trans-Activators / metabolism; Viral Proteins / genetics; Viral Proteins / metabolism; Virulence; Virus Replication
TL;DR:
It is established that the GRS is a conserved, essential motif characteristic of an ancient lineage of rolling-circle initiators and support the idea that geminiviruses may have evolved from plasmids associated with phytoplasma or algae.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
A new technique using metal tags to track small seeds over short distances
Ecological Research, 26(1), 233–236.
Source: NC State University Libraries
Added: August 6, 2018
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