Works Published in 2009
Displaying works 1 - 20 of 78 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2009 journal article
Sexual Development in <i>Lucilia cuprina</i> (Diptera, Calliphoridae) Is Controlled by the Transformer Gene
Genetics, 182(3), 785–798.
TL;DR:
The results suggest that an autoregulatory loop sustains female development and that expression of M inhibits LctraAutoregulation, switching its splicing to the male form, shows that this sex determination system is not confined to Tephritidae.
(via Semantic Scholar)
www.genetics.org (publisher PDF)
Source: Crossref
Added: February 2, 2024
2009 journal article
Sexual development in Lucilia cuprina (Diptera, Calliphoridae) is controlled by the transformer gene
Genetics, 182(3), 785–798.
Source: ORCID
Added: January 29, 2024
2009 journal article
Measuring and partitioning the high-order linkage disequilibrium by multiple order Markov chains
Genetic Epidemiology, 33(2), 181–181.
TL;DR:
Measuring and Partitioning the High-Order Linkage Disequilibrium by Multiple Order Markov Chains by Multiple order Markov chains and Zhao-Bang Zeng Bioinformatics Research Center.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
4. Quality Education
(OpenAlex)
Source: Crossref
Added: April 4, 2021
2009 journal article
Proceedings of the First International Conference on Toxicogenomics Integrated with Environmental Sciences (TIES-2007)
BMC Proceedings, 3(S2).
TL;DR:
A collection of articles as proceedings of the conference and an in-depth topical review of the utility of bioinformatics in the fields of toxicogenomics and environmental genomics are compiled.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 5, 2020
2009 chapter
Isolation of Peptide Aptamers to Target Protein Function
In Methods in Molecular Biology (pp. 333–360).
MeSH headings : Amino Acid Sequence; Aptamers, Peptide / chemistry; Aptamers, Peptide / genetics; Aptamers, Peptide / metabolism; Peptide Library; Protein Binding; Protein Interaction Domains and Motifs; Proteins / chemistry; Proteins / genetics; Proteins / metabolism; SELEX Aptamer Technique / methods; Two-Hybrid System Techniques
TL;DR:
High-throughput protocols that facilitate the selection and characterization of peptide aptamers from yeast dihybrid libraries are described, including the preparation and evaluation of the bait fusion and the peptideaptamer screen.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 13, 2020
2009 journal article
A combinatorial interplay among the 1-aminocyclopropane-1-carboxylate isoforms regulates ethylene biosynthesis in Arabidopsis thaliana
Genetics, 183(3), 979–1003.
Contributors: A. Tsuchisaka*, G. Yu*, H. Jin *, J. Alonso *, J. Ecker *, X. Zhang *, S. Gao *, A. Theologis*
MeSH headings : Amino Acids, Cyclic / metabolism; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Epistasis, Genetic; Ethylenes / biosynthesis; Flowers / genetics; Flowers / growth & development; Flowers / metabolism; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Complementation Test; Genome, Plant / genetics; Isoenzymes / genetics; Isoenzymes / metabolism; Lyases / genetics; Lyases / metabolism; Mutation; Plant Diseases / genetics; Plant Diseases / microbiology; Plants, Genetically Modified; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine / metabolism; Time Factors
TL;DR:
The lethality of the null ACS mutant contrasts with the viability of null mutations in key components of the ethylene signaling apparatus, strongly supporting the view that ACC, the precursor of ethylene, is a primary regulator of plant growth and development.
(via Semantic Scholar)
Source: ORCID
Added: December 19, 2019
2009 chapter
Plant Genome Engineering Using Zinc Finger Nucleases
In Molecular Techniques in Crop Improvement (pp. 579–590).
TL;DR:
ZFN-mediated gene targeting is likely to become a powerful technique for precise modification and directed mutagenesis of plant and mammalian genomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: March 2, 2019
2009 book
It takes a genome: How a clash between our genes and modern life is making us sick
Upper Saddle River, N.J. : Pearson Education.
Source: NC State University Libraries
Added: August 6, 2018
2009 journal article
Using association mapping in teosinte to investigate the function of maize selection-candidate genes
PLoS One, 4(12).
Source: NC State University Libraries
Added: August 6, 2018
2009 journal article
SIMULATION FROM ENDPOINT-CONDITIONED, CONTINUOUS-TIME MARKOV CHAINS ON A FINITE STATE SPACE, WITH APPLICATIONS TO MOLECULAR EVOLUTION
ANNALS OF APPLIED STATISTICS, 3(3), 1204–1231.
author keywords: Continuous-time Markov chains; simulation; molecular evolution
TL;DR:
This work considers the generation of sample paths, including intermediate states and times of transition, from a CTMC whose beginning and ending states are known across a time interval of length T, and introduces and compares three applications of CTMCs to demonstrate the pitfalls of choosing an inefficient sampler.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Pharmacogenetic association study of 30 genes with phenobarbital drug response in epileptic dogs
PHARMACOGENETICS AND GENOMICS, 19(12), 911–922.
author keywords: canine epilepsy; drug response; epoxide hydrolase; GABRA2; KCNQ3; pharmacogenetics; phenobarbital; SCN2A2
MeSH headings : Animals; Anticonvulsants / metabolism; Anticonvulsants / therapeutic use; Case-Control Studies; Dog Diseases / drug therapy; Dogs; Drug Resistance; Epilepsy / drug therapy; Epilepsy / veterinary; Pharmacogenetics; Phenobarbital / metabolism; Phenobarbital / therapeutic use; Polymorphism, Single Nucleotide
TL;DR:
Further replication and assessment of breed specificity is required before these markers can be considered as predictive of responsiveness to phenobarbital in dogs, but on functional grounds may tag strong candidate genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Epidermal Growth Factor Receptor Is Required for Colonic Tumor Promotion by Dietary Fat in the Azoxymethane/Dextran Sulfate Sodium Model: Roles of Transforming Growth Factor-alpha and PTGS2
CLINICAL CANCER RESEARCH, 15(22), 6780–6789.
MeSH headings : Animals; Azoxymethane / pharmacology; Blood Glucose / metabolism; Colonic Neoplasms / metabolism; Cyclooxygenase 2 / metabolism; Dextran Sulfate / pharmacology; ErbB Receptors / metabolism; Gene Expression Regulation, Neoplastic; Insulin / blood; Insulin Resistance; Ligands; Mice; Mice, Inbred C57BL; Point Mutation; Transforming Growth Factor alpha / metabolism
TL;DR:
Egfrwt mice gained significantly more weight and had exaggerated insulin resistance compared with Egfrwa2 mice on high-fat diet, and EGFR-dependent increases in receptor ligands and PTGS2 likely drive diet-related tumor promotion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Association of orthodenticle with Natural Variation for Early Embryonic Patterning in Drosophila melanogaster
JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION, 312B(8), 841–854.
MeSH headings : Animals; Animals, Genetically Modified; Base Sequence; Body Patterning; DNA Primers; Drosophila Proteins / genetics; Drosophila melanogaster / embryology; Drosophila melanogaster / genetics; Enhancer Elements, Genetic; Female; Gene Expression; Haplotypes; Homeodomain Proteins / genetics; In Situ Hybridization; Molecular Sequence Data; Polymorphism, Genetic; Sequence Homology, Nucleic Acid
TL;DR:
It is demonstrated that even a process as robust as early developmental patterning is affected by standing genetic variation, intriguingly involving otd, whose morphogenetic function bicoid is thought to have displaced during dipteran evolution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Age, but not experience, affects courtship gene expression in male Drosophila melanogaster
PLoS One, 4(7).
Source: NC State University Libraries
Added: August 6, 2018
2009 article
Toll-like receptor activation profiles of wild-type, recombinant, and mutant Lactobacillus: implications for vaccine design
RETROVIROLOGY, Vol. 6.
TL;DR:
This work is investigating the use of Lactobacillus spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Quantitative Trait Loci for Aggressive Behavior in Drosophila melanogaster
GENETICS, 182(3), 889–897.
MeSH headings : Aggression; Analysis of Variance; Animals; Chromosome Mapping; Crosses, Genetic; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Female; Genes, Insect / genetics; Genetic Complementation Test; Genetic Variation; Genome, Insect / genetics; Male; Mutation; Quantitative Trait Loci / genetics
TL;DR:
QTL affecting variation in aggression between two wild-type Drosophila strains is mapped and extensive epistasis poses a serious challenge for understanding the genetic basis of complex traits.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Plant cell calcium-rich environment enhances thermostability of recombinantly produced alpha-amylase from the hyperthermophilic bacterium Thermotoga maritime
Biotechnology and Bioengineering, 104(5), 947–956.
author keywords: hyperthermophilic enzymes; starch processing; transgenic plants; tobacco NT1 Cell cultures; biofuel
MeSH headings : Calcium / pharmacology; Coenzymes / pharmacology; Enzyme Stability; Escherichia coli / enzymology; Escherichia coli / genetics; Hot Temperature; Plants, Genetically Modified / enzymology; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Thermotoga maritima / enzymology; Thermotoga maritima / genetics; Tobacco / enzymology; Tobacco / genetics; alpha-Amylases / chemistry; alpha-Amylases / genetics; alpha-Amylases / metabolism
TL;DR:
In a proof of concept study, tobacco cell cultures were used as model system to test in planta production of a hyperthermophilic α‐amylase from Thermotoga maritima, demonstrating the importance of a calcium‐rich environment for thermostability, as well as the advantage of producing this enzyme directly in plant cells where calcium is readily available.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2009 journal article
Placental and Embryonic Growth Restriction in Mice With Reduced Function Epidermal Growth Factor Receptor Alleles
GENETICS, 183(1), 207–218.
MeSH headings : Alleles; Animals; Animals, Newborn; Embryo, Mammalian; Female; Fetal Growth Retardation / genetics; Fetal Growth Retardation / mortality; Fetal Growth Retardation / pathology; Genes, erbB-1 / physiology; Homozygote; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Organ Size / genetics; Placenta / pathology; Placenta Diseases / genetics; Placenta Diseases / mortality; Placenta Diseases / pathology; Placentation; Pregnancy; Species Specificity
TL;DR:
It is suggested that Egfrwa2 homozygous embryos model EGFR-mediated intrauterine growth restriction in humans and differential expression in the placenta of Glut3, a glucose transporter essential for normal embryonic growth, may contribute to strain-dependent differences in intrauterne growth restriction caused by reduced EGFR activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 article
Immunogenicity of Lactobacillus gasseri-FliC as an oral mucosal vaccine adjuvant for HIV
RETROVIROLOGY, Vol. 6.
TL;DR:
The immunogenicity of a novel Lactobacillus gasseri mucosal vaccine vector for use in oral delivery of HIV antigens is investigated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Candidate Gene Association Mapping of Arabidopsis Flowering Time
GENETICS, 183(1), 325–335.
MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Chromosome Mapping; Crosses, Genetic; Flowers / genetics; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Gene Regulatory Networks; Genes, Plant / physiology; Genetic Linkage; Genotype; Polymorphism, Single Nucleotide; Time Factors
TL;DR:
Using structured association techniques, it is found that haplotype-tagging SNPs in 27 flowering time genes show significant associations in various trait/environment combinations, and it is conservatively estimated that ∼4–14% of known floweringTime genes may harbor common alleles that contribute to natural variation in this life history trait.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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