Works Published in 2010

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Displaying works 1 - 20 of 46 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2010 journal article

Organisation and expression of a cluster of yolk protein genes in the Australian sheep blowfly, Lucilia cuprina

Genetica, 139(1), 63–70.

By: M. Scott n, A. Atapattu*, A. Schiemann*, C. Concha*, R. Henry*, B. Carey*, E. Belikoff n, J. Heinrich*, A. Sarkar*

MeSH headings : Amino Acid Sequence; Animals; Animals, Genetically Modified / genetics; Australia; Diptera / genetics; Egg Proteins / genetics; Female; Gene Expression Regulation; Genes, Insect; Genetic Vectors; Germ Cells; Male; Molecular Sequence Data; Multigene Family; New Zealand; Sheep / parasitology; Transformation, Genetic; Transgenes
TL;DR: The sequence of a 14.2 kb genomic clone from L. cuprina that contains a cluster of three complete yp genes and one partial yp gene is reported, suggesting the LcypA promoter could be used to obtain female-specific expression of tTA in transgenic L.cuprina. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Crossref
Added: January 30, 2024

2010 journal article

Structural and biochemical studies on the chromo-barrel domain of male specific lethal 3 (MSL3) reveal a binding preference for mono-or dimethyllysine 20 on histone H4

Journal of Biological Chemistry, 285(52), 40879–40890.

By: S. Moore, Y. Ferhatoglu, Y. Jia, R. Al-Jiab & M. Scott

Source: ORCID
Added: January 29, 2024

2010 report

Power, sample size and confidence interval for quantitative trait loci mapping on multiple traits

By: L. E Silva, S. Chang & Z. Zeng

Source: NC State University Libraries
Added: August 16, 2021

2010 journal article

Proteomic and Bioinformatic Analysis of the Root-Knot Nematode Meloidogyne hapla: The Basis for Plant Parasitism

Journal of Proteome Research, 9(10), 5370–5381.

By: F. Mbeunkui n, E. Scholl n, C. Opperman n, M. Goshe n & D. Bird n

author keywords: LC/MSE; plant-parasite; nematode; data-independent acquisition; computational proteome
MeSH headings : Animals; Chromatography, Liquid; Computational Biology / methods; Databases, Protein; Genome, Helminth / genetics; Helminth Proteins / genetics; Helminth Proteins / metabolism; Humans; Internet; Plant Roots / parasitology; Proteomics / methods; Tandem Mass Spectrometry; Tylenchoidea / genetics; Tylenchoidea / metabolism
TL;DR: To experimentally confirm the HapPep3 assignments using proteomics, a data-independent LC/MS(E) analysis to M. hapla protein extracts fractionated by SDS-PAGE was applied, and it was concluded that the identified proteins reflect a true and unbiased sampling of Happep3. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Crossref
Added: November 26, 2020

2010 journal article

Altered Gene Expression and DNA Damage in Peripheral Blood Cells from Friedreich's Ataxia Patients: Cellular Model of Pathology

PLoS Genetics, 6(1), e1000812.

By: A. Haugen*, N. Di Prospero*, J. Parker, R. Fannin*, J. Chou*, J. Meyer*, C. Halweg*, J. Collins* ...

Ed(s): C. Pearson

MeSH headings : Adolescent; Adult; Cells, Cultured; Child; Cohort Studies; DNA Damage; Female; Friedreich Ataxia / genetics; Friedreich Ataxia / pathology; Gene Expression; Humans; Iron-Binding Proteins / genetics; Male; Middle Aged; RNA / blood; RNA / genetics; Young Adult
TL;DR: The data suggest that patients with prolonged frataxin deficiency undergo a systemic survival response to chronic genotoxic stress and consequent DNA damage detectable in blood, which may have predictive value in future clinical trials. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 28, 2019

2010 journal article

Glycine and a Glycine Dehydrogenase (GLDC) SNP as Citalopram/Escitalopram Response Biomarkers in Depression: Pharmacometabolomics-Informed Pharmacogenomics

Clinical Pharmacology & Therapeutics, 89(1), 97–104.

By: Y. Ji*, S. Hebbring*, H. Zhu n, G. Jenkins*, J. Biernacka*, K. Snyder*, M. Drews*, O. Fiehn* ...

MeSH headings : Biomarkers, Pharmacological / blood; Cell Line; Chromosomes, Human, Pair 9 / genetics; Citalopram / therapeutic use; DNA-Binding Proteins / metabolism; Depressive Disorder, Major / blood; Depressive Disorder, Major / drug therapy; Depressive Disorder, Major / genetics; Drug Monitoring / methods; Female; Genetic Association Studies; Glycine / blood; Glycine / metabolism; Glycine Dehydrogenase (Decarboxylating) / genetics; Humans; Introns / genetics; Linkage Disequilibrium; Male; Metabolome / drug effects; Nuclear Proteins / metabolism; Polymorphism, Single Nucleotide; Selective Serotonin Reuptake Inhibitors / therapeutic use
TL;DR: A possible role for glycine in SSRI response is highlighted and the use of pharmacometabolomics‐informed pharmacogenomic research strategy to identify citalopram/escitaloprams treatment outcome biomarkers is illustrated to “inform” pharmacogenomics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Crossref
Added: July 28, 2019

2010 journal article

Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study

Metabolomics, 6(2), 191–201.

By: R. Kaddurah-Daouk*, R. Baillie*, H. Zhu n, Z. Zeng n, M. Wiest*, U. Nguyen*, S. Watkins*, R. Krauss

author keywords: Cardiovascular disease; Lipidomics; Metabolomics; Pharmacogenomics; Pharmacometabolomics; Simvastatin
TL;DR: There was no overlap of lipids whose changes correlated with LDL-C or CRP responses to simvastatin suggesting that distinct metabolic pathways govern statin effects on these two biomarkers. (via Semantic Scholar)
Source: Crossref
Added: July 20, 2019

2010 article

Floral Homeotic Gene Regulation

Franks, R. G., & Liu, Z. (2010, June). Horticultural Reviews, pp. 41–77.

By: R. Franks* & Z. Liu*

Source: ORCID
Added: January 22, 2019

2010 journal article

Sex-biased transcription enhancement by a 5' tethered Gal4-MOF histone acetyltransferase fusion protein in Drosophila

BMC Molecular Biology, 11(1).

MeSH headings : Acetylation; Amino Acid Sequence; Animals; DNA-Binding Proteins / analysis; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Drosophila / enzymology; Drosophila / genetics; Drosophila / metabolism; Drosophila Proteins / analysis; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Female; Genes, Reporter; Genes, X-Linked; Histone Acetyltransferases / analysis; Histone Acetyltransferases / genetics; Histone Acetyltransferases / metabolism; Histones / genetics; Histones / metabolism; Male; Models, Molecular; Molecular Sequence Data; Nuclear Proteins / analysis; Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Polytene Chromosomes / chemistry; Recombinant Fusion Proteins / analysis; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; Saccharomyces cerevisiae Proteins / analysis; Saccharomyces cerevisiae Proteins / genetics; Saccharomyces cerevisiae Proteins / metabolism; Sequence Alignment; Sex Factors; Transcription Factors / analysis; Transcription Factors / genetics; Transcription Factors / metabolism; Transcriptional Activation
TL;DR: Targeting MOF to reporter genes led to transcription enhancement and acetylation of histone H4 at lysine 16 and how association of Gal4-MOF with the MSL or NSL proteins could explain the results is discussed. (via Semantic Scholar)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2010 journal article

Factors associated with sow stayability in 6 genotypes

JOURNAL OF ANIMAL SCIENCE, 88(11), 3486–3492.

By: M. Knauer*, K. Stalder*, T. Serenius*, T. Baas*, P. Berger*, L. Karriker*, R. Goodwin*, R. Johnson* ...

author keywords: genetic; longevity; sow; stayability
MeSH headings : Adipose Tissue; Animals; Female; Fertility / genetics; Genetic Variation; Genotype; Longevity / genetics; Reproduction / genetics; Swine / genetics; Swine / physiology
TL;DR: Association of production factors with stayability to parity 4 (STAY4) under controlled experimental conditions included farm, entry date, age at first farrowing, ADG, gilt backfat, and lactation before removal effects, as well as feed intake, number born alive, and breastfeeding length. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

The phylogenetic position of the bumble bee inquiline Bombus inexspectatus and implications for the evolution of social parasitism

Insectes Sociaux, 57(4), 379–383.

By: H. Hines & S. Cameron

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

The importance of location and orientation of male specific lethal complex binding sites of differing affinities on reporter gene dosage compensation in Drosophila

Biochemical and Biophysical Research Communications, 402(4), 699–704.

By: A. Schiemann, V. Weake, F. Li, C. Laverty, E. Belikoff & M. Scott*

author keywords: Dosage compensation; Epigenetics; MSL complex; Transcription
MeSH headings : 3' Untranslated Regions; Animals; Binding Sites; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Dosage Compensation, Genetic; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / genetics; Genes, Reporter; Male; Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Promoter Regions, Genetic; Transcription Factors / genetics; Transcription Factors / metabolism; Transgenes; beta-Galactosidase / genetics
TL;DR: The results suggest that MSL complex binding to weaker sites and transcription enhancement is influenced by gene transcription, binding site orientation and the local chromatin environment, while strong binding sites do not need to be transcribed to recruit sufficient complex to cause transcription elevation of nearby genes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2010 journal article

Identification of a Promoter for the Human C1q-Tumor Necrosis Factor-Related Protein-5 Gene Associated with Late-Onset Retinal Degeneration

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 51(11), 5499–5507.

By: V. Chavali*, J. Sommer n, R. Petters n & R. Ayyagari*

MeSH headings : 3' Untranslated Regions / genetics; Animals; Base Sequence; Blotting, Western; Cell Line; Collagen / genetics; Fluorescent Antibody Technique, Indirect; Gene Amplification; Gene Expression Regulation / physiology; Humans; Membrane Proteins / genetics; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic / genetics; Retinal Degeneration / genetics; Retinal Pigment Epithelium / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Transfection
TL;DR: This study revealed the presence of a functional promoter for the CTRP5 gene located 5' of its start site, and the predicted hCTRP5 promoter was found to control the expression of V5-tagged pCT RP5 and nuclear GFP, indicating that the promoter was functional. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Genetic mapping and developmental timing of transmission ratio distortion in a mouse interspecific backcross

BMC GENETICS, 11.

By: C. Eversley*, T. Clark*, Y. Xie*, J. Steigerwalt*, T. Bell*, F. Villena*, D. Threadgill n

MeSH headings : Alleles; Animals; Chromosome Mapping; Female; Genotype; Hybridization, Genetic; Inheritance Patterns; Male; Mice / genetics; Mice, Inbred A; Microsatellite Repeats; Models, Genetic
TL;DR: The results are consistent with the TRD mechanism being deviation from Mendelian inheritance rather than meiotic drive or segregation distortion, and the underlying causes for the interspecific TRD events are the differential post-natal survival of pups with specific genotypes. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Functional and phenotypic characterization of a protein from Lactobacillus acidophilus involved in cell morphology, stress tolerance and adherence to intestinal cells

MICROBIOLOGY-SGM, 156, 3360–3367.

By: . Sarah J. O'Flaherty & T. Klaenhammer n

MeSH headings : Bacterial Adhesion; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Caco-2 Cells; Cell Wall / metabolism; Gene Deletion; Humans; Intestines / microbiology; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / growth & development; Lactobacillus acidophilus / metabolism; Membrane Proteins / genetics; Membrane Proteins / metabolism; Mutation; Stress, Physiological
TL;DR: Results indicate a role for LBA649 in stress tolerance, cell wall division and adherence to Caco-2 cells in L. acidophilus NCFM. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Conservation and sex-specific splicing of the doublesex gene in the economically important pest species Lucilia cuprina

Journal of Genetics, 89(3), 279–285.

author keywords: doublesex; sex determination; alternative splicing; Lucilia cuprina
MeSH headings : 3' Untranslated Regions / genetics; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Conserved Sequence / genetics; Diptera / genetics; Exons / genetics; Female; Genes, Insect / genetics; Insect Proteins / chemistry; Insect Proteins / genetics; Male; Molecular Sequence Data; RNA Splicing / genetics; Sequence Alignment; Sex Characteristics
TL;DR: The dsx gene (Lcdsx) is isolated from the Australian sheep blowfly and it is found that the LcdsX transcripts are sex-specifically spliced in a similar manner as their counterparts in D. melanogaster, housefly and tephritids. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2010 journal article

Synergistic disruptions in seuss cyp85A2 double mutants reveal a role for brassinolide synthesis during gynoecium and ovule development

BMC PLANT BIOLOGY, 10.

Contributors: S. Nole-Wilson n, E. Rueschhoff n, H. Bhatti n & R. Franks n

MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Brassinosteroids; Cholestanols / metabolism; Chromosome Mapping; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; DNA, Plant / genetics; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genetic Complementation Test; Genotype; Mutagenesis, Insertional; Mutation; Ovule / growth & development; Plant Growth Regulators / biosynthesis; Steroids, Heterocyclic / metabolism
TL;DR: The identification of mutations in CYP85A2 as enhancers of the seuss mutant phenotype suggests a previously unrecognized role for brassinolide synthesis in gynoecial and ovule outer integument development and suggests that seuss mutants may be more sensitive to the loss or reduction of brassinlide synthesis than are wild type plants. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Polar auxin transport together with AINTEGUMENTA and REVOLUTA coordinate early Arabidopsis gynoecium development

DEVELOPMENTAL BIOLOGY, 346(2), 181–195.

By: S. Note-Wilson, S. Azhakanandam n & R. Franks n

Contributors: S. Nole-Wilson n, S. Azhakanandam n & R. Franks n

author keywords: NPA; Replum; Carpel margin meristem; TAA1; PHABULOSA; Homeodomain-leucine zipper
MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Biological Transport / physiology; Flowers / growth & development; Gene Expression Regulation, Plant; Indoleacetic Acids / metabolism; Mutation; Phenotype; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: It is demonstrated that auxin transport is required for the development of the medial ovary domain that contains the carpel margin meristem, a vital female reproductive structure, and suggested that an auxin-mediated positional cue is important for the differential specification ofThe medial and lateral ovary domains. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

HYBRIDIZATION AND INTROGRESSION IN NEW WORLD RED MANGROVES, RHIZOPHORA (RHIZOPHORACEAE)

AMERICAN JOURNAL OF BOTANY, 97(6), 945–957.

By: I. Ceron-Souza*, E. Rivera-Ocasio*, E. Medina*, J. Jimenez, W. McMillan n & E. Bermingham*

author keywords: Central American Isthmus; evolutionary history; hybridiation; introgression; Rhizophora harrisonii; Rhizophora mangle; Rhizophora racemosa; Rhizophoraceae
TL;DR: The data support ancient and persistent introgressive hybridization among new world Rhizophora and argue for a full revision of the systematic relationships of the group based on much finer morphological, ecological, and genetic analyses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Genomic hotspots for adaptation: The population genetics of Mullerian mimicry in the Heliconius melpomene Clade

PLoS Genetics, 6(4).

By: S. Baxter, N. Nadeau, L. Maroja, P. Wilkinson, B. Counterman, A. Dawson, M. Beltran, S. Perez-Espona ...

Source: NC State University Libraries
Added: August 6, 2018

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