Genetics
College of Sciences
Works Published in 2012
Displaying works 1 - 20 of 58 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2012 journal article
Epistasis dominates the genetic architecture of Drosophila quantitative traits
Proceedings of the National Academy of Sciences, 109(39), 15553–15559.
author keywords: chill coma recovery; genetic interaction networks; genome-wide association studies; startle response; starvation resistance
MeSH headings : Animals; Drosophila melanogaster; Epistasis, Genetic / physiology; Genes, Insect / physiology; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable
www.pnas.org (publisher PDF)
Source: Crossref
Added: August 28, 2020
2012 journal article
The Drosophila melanogaster Genetic Reference Panel
Nature, 482(7384), 173–178.
MeSH headings : Alleles; Animals; Centromere / genetics; Chromosomes, Insect / genetics; Drosophila melanogaster / genetics; Genome-Wide Association Study; Genomics; Genotype; Phenotype; Polymorphism, Single Nucleotide / genetics; Quantitative Trait Loci / genetics; Selection, Genetic / genetics; Starvation / genetics; Telomere / genetics; X Chromosome / genetics
Source: Crossref
Added: August 28, 2020
2012 journal article
The interface of protein structure, protein biophysics, and molecular evolution
Protein Science, 21(6), 769–785.
author keywords: evolutionary modeling; domain evolution; sequence-structure-function relationships; protein dynamics; protein thermodynamics; gene duplication; protein expression; ancestral sequence reconstruction
MeSH headings : Amino Acid Sequence; Animals; Evolution, Molecular; Humans; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Folding; Proteins / chemistry; Proteins / genetics; RNA, Messenger / genetics; Sequence Alignment
Source: Crossref
Added: August 28, 2020
2012 journal article
AUX/LAX genes encode a family of auxin influx transporters that perform distinct functions during Arabidopsis development
The Plant Cell Online, 24(7), 2874–2885.
MeSH headings : Arabidopsis / cytology; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Biological Transport; Body Patterning; Cotyledon / cytology; Cotyledon / genetics; Cotyledon / growth & development; Cotyledon / metabolism; Gene Knockout Techniques; Indoleacetic Acids / metabolism; Membrane Transport Proteins / genetics; Membrane Transport Proteins / metabolism; Multigene Family; Mutagenesis, Insertional; Phenotype; Plant Roots / cytology; Plant Roots / genetics; Plant Roots / growth & development; Plant Roots / metabolism; Plant Vascular Bundle / cytology; Plant Vascular Bundle / genetics; Plant Vascular Bundle / growth & development; Plant Vascular Bundle / metabolism; Plants, Genetically Modified; Seedlings / cytology; Seedlings / genetics; Seedlings / growth & development; Seedlings / metabolism
Source: ORCID
Added: December 19, 2019
2012 journal article
Differential effects of poly(ADP-ribose) polymerase inhibition on DNA break repair in human cells are revealed with Epstein-Barr virus
Proceedings of the National Academy of Sciences, 109(17), 6590–6595.
author keywords: base excision repair; BRCA
MeSH headings : Blotting, Western; Cell Cycle; DNA Damage; DNA Repair; Enzyme Inhibitors / pharmacology; Herpesvirus 4, Human / physiology; Humans; Infrared Rays; Plasmids / physiology; Poly(ADP-ribose) Polymerase Inhibitors; Polymerase Chain Reaction; Tumor Suppressor Protein p53 / physiology
Sources: Crossref, ORCID
Added: September 28, 2019
2012 chapter
Composite Interval Mapping and Multiple Interval Mapping: Procedures and Guidelines for Using Windows QTL Cartographer
In Methods in Molecular Biology (pp. 75–119).
MeSH headings : Animals; Drosophila melanogaster / genetics; Inbreeding; Models, Statistical; Quantitative Trait Loci / genetics; Software
Source: Crossref
Added: July 20, 2019
2012 journal article
Metabolomics Reveals Amino Acids Contribute to Variation in Response to Simvastatin Treatment
PLoS ONE, 7(7), e38386.
Ed(s): M. Oresic
MeSH headings : Adult; Amino Acids, Essential / blood; Biomarkers, Pharmacological / blood; Cholesterol, LDL / blood; Citrulline / blood; Cystine / blood; Female; Fructose / blood; Gas Chromatography-Mass Spectrometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacology; Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use; Lauric Acids / blood; Male; Metabolomics; Nitric Oxide Synthase / blood; Ornithine / blood; Simvastatin / pharmacology; Simvastatin / therapeutic use; Stearic Acids / blood; Succinic Acid / blood; Xanthine / blood; alpha-Tocopherol / blood
Source: Crossref
Added: July 20, 2019
2012 journal article
Evolution of bract development and B-class MADS box gene expression in petaloid bracts of cornus s. l. (cornaceae)
New Phytologist, 196(2), 631–643.
author keywords: APETALA3; B-class gene expression; Cornus; development; Evo-Devo; evolution of petaloid bracts; heterotopic petaloidy; PISTILLATA
MeSH headings : Biological Evolution; Cell Shape; Cornaceae / anatomy & histology; Cornaceae / genetics; Cornaceae / growth & development; Cornaceae / ultrastructure; Flowers / cytology; Flowers / genetics; Flowers / growth & development; Flowers / ultrastructure; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genes, Plant / genetics; Inflorescence / growth & development; MADS Domain Proteins / genetics; MADS Domain Proteins / metabolism; Phylogeny; Plant Epidermis / cytology; Plant Epidermis / ultrastructure; Plant Leaves / cytology; Plant Leaves / genetics; Plant Leaves / growth & development; Plant Leaves / ultrastructure; Plant Proteins / genetics; Plant Proteins / metabolism; Seasons; Time Factors
Source: ORCID
Added: January 22, 2019
2012 journal article
Photoreceptor Differentiation following Transplantation of Allogeneic Retinal Progenitor Cells to the Dystrophic Rhodopsin Pro347Leu Transgenic Pig
STEM CELLS INTERNATIONAL, 2012.
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Multiple trait multiple interval mapping of quantitative trait loci from inbred line crosses
BMC Genetics, 13.
Source: NC State University Libraries
Added: August 6, 2018
2012 journal article
Influence of Exposure Time on Gene Expression by Human Intestinal Epithelial Cells Exposed to Lactobacillus acidophilus
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78(14), 5028–5032.
MeSH headings : Caco-2 Cells; Epithelial Cells / immunology; Epithelial Cells / metabolism; Epithelial Cells / microbiology; Flagellin / metabolism; Flagellin / pharmacology; Gene Expression Profiling; Gene Expression Regulation; Humans; Intestinal Mucosa / metabolism; Intestines / cytology; Intestines / immunology; Intestines / microbiology; Lactobacillus acidophilus / immunology; Molecular Sequence Data; NF-kappa B / genetics; NF-kappa B / metabolism; Probiotics / pharmacology; Recombinant Proteins / metabolism; Recombinant Proteins / pharmacology; Time Factors
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Construction and Immunological Evaluation of Dual Cell Surface Display of HIV-1 Gag and Salmonella enterica Serovar Typhimurium FliC in Lactobacillus acidophilus for Vaccine Delivery
CLINICAL AND VACCINE IMMUNOLOGY, 19(9), 1374–1381.
MeSH headings : AIDS Vaccines / administration & dosage; AIDS Vaccines / genetics; AIDS Vaccines / immunology; Administration, Oral; Animals; Bacterial Vaccines / administration & dosage; Bacterial Vaccines / genetics; Bacterial Vaccines / immunology; Cell Surface Display Techniques / methods; Cells, Cultured; Dendritic Cells / immunology; Female; Flagellin / genetics; Flagellin / immunology; HIV-1 / genetics; HIV-1 / immunology; Humans; Intestinal Mucosa / immunology; Lactobacillus acidophilus / genetics; Leukocytes, Mononuclear / immunology; Mice; Mice, Inbred BALB C; Salmonella typhimurium / genetics; Salmonella typhimurium / immunology; Vaccines, Synthetic / administration & dosage; Vaccines, Synthetic / genetics; Vaccines, Synthetic / immunology; gag Gene Products, Human Immunodeficiency Virus / genetics; gag Gene Products, Human Immunodeficiency Virus / immunology
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Characterization of the fecal microbiota using high-throughput sequencing reveals a stable microbial community during storage
PLoS One, 7(10).
MeSH headings : Bacteria / classification; Bacteria / genetics; Bacteria / growth & development; Biodiversity; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Feces / microbiology; Freezing; Genetic Variation; Humans; Intestines / microbiology; Irritable Bowel Syndrome / microbiology; Metagenome / genetics; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA / methods; Specimen Handling / methods; Time Factors
Source: NC State University Libraries
Added: August 6, 2018
2012 journal article
AUX/LAX genes encode a family of auxin influx transporters that perform distinct functions during arabidopsis development
Plant Cell, 24(7), 2874–2885.
Source: NC State University Libraries
Added: August 6, 2018
2012 journal article
The impact of probiotics and prebiotics on the immune system
NATURE REVIEWS IMMUNOLOGY, 12(10), 728–734.
MeSH headings : Animals; Humans; Immune System; Immunomodulation; Prebiotics; Probiotics
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Impact of Genetic Architecture on the Relative Rates of X versus Autosomal Adaptive Substitution
MOLECULAR BIOLOGY AND EVOLUTION, 29(8), 1933–1942.
author keywords: dominance; epistasis; genetics of adaptation; soft sweeps; molecular evolution
MeSH headings : Adaptation, Physiological / genetics; Animals; Chromosomes, Human, X / genetics; Evolution, Molecular; Genes / genetics; Humans; Models, Genetic; Mutation / genetics; Phylogeny; Population Density; X Chromosome / genetics
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Fitting nonstationary general-time-reversible models to obtain edge-lengths and frequencies for the barry-hartigan model
Systematic Biology, 61(6), 927–940.
Source: NC State University Libraries
Added: August 6, 2018
2012 journal article
Efficacy of EGFR Inhibition Is Modulated by Model, Sex, Genetic Background and Diet: Implications for Preclinical Cancer Prevention and Therapy Trials
PLOS ONE, 7(6).
MeSH headings : Animals; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Azoxymethane / toxicity; Colorectal Neoplasms / chemically induced; Colorectal Neoplasms / drug therapy; Colorectal Neoplasms / genetics; Diet; Disease Models, Animal; ErbB Receptors / antagonists & inhibitors; ErbB Receptors / metabolism; Female; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Quinazolines / pharmacology; Quinazolines / therapeutic use; Sex Factors; Tyrphostins / pharmacology; Tyrphostins / therapeutic use
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Developmental plasticity and the evolution of parasitism in an unusual nematode, Parastrongyloides trichosuri
EVODEVO, 3.
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Age-specific variation in immune response in drosophila melanogaster has a genetic basis
Genetics, 191(3), 989–584.
Source: NC State University Libraries
Added: August 6, 2018
