Molecular Education, Technology and Research Innovation Center

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Sorted by most recent date added to the index first, which may not be the same as publication date order.

2025 journal article

A versatile and efficient method to quantify purity and degree of substitution in alginate derivatives

Carbohydrate Polymers.

By: M. Carpio, P. Thompson*, C. Moody, J. Pierce & Y. Brudno

topics (OpenAlex): 3D Printing in Biomedical Research; Hydrogels: synthesis, properties, applications; Biopolymer Synthesis and Applications
Source: ORCID
Added: September 2, 2025

2025 article

Detection and Quantitation of Per- and Polyfluoroalkyl Substances in North Carolina Sea Foam and the Corresponding Sea Water

Environmental Science & Technology.

By: J. Enders, R. Weed, E. Donovan, D. Phelps, G. Campbell, K. May, E. Baker

author keywords: PFAS contamination; sea foam accumulation; high-resolution mass spectrometry (HRMS); quantitative analysis; nontargeted analysis; per- and polyfluoroalkyl substances(PFAS); emerging PFAS compounds
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 27, 2025

2025 article

Characterization of an isobutylene epoxide hydrolase (IbcK) from the isobutylene-catabolizing bacterium <i>Mycolicibacterium</i> sp. ELW1

Faulkner, N. W., Joyce, J. B., Smith, C., Swartz, P., Rose, R. B., Miller, E. S., & Hyman, M. R. (2025, August 26). (M. Vives, Ed.). APPLIED AND ENVIRONMENTAL MICROBIOLOGY.

By: N. Faulkner, J. Joyce, C. Smith, P. Swartz, R. Rose, E. Miller, M. Hyman

Ed(s): M. Vives

author keywords: epoxide hydrolase; isobutylene; isobutylene oxide; MTBE; alkenes; bioremediation
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 26, 2025

2025 article

Mechanistic Insights into Visible-Light-Induced ATRA Reactions Powered by the Symbiotic Relationship between Cu(II)/Cu(I) Phenanthroline Complexes

Arteta, S., Deegbey, M., Durand, N., Kibbe, R., Floss, J., Barth, A. T., … Castellano, F. N. (2025, August 26). ACS CATALYSIS, Vol. 8.

author keywords: photochemistry; photocatalysts; charge transfer; copper phenanthrolines; ATRA reactions
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 26, 2025

2025 journal article

Injection of vocal fold lamina propria-derived hydrogels modulates fibrosis in injured vocal folds

BIOMATERIALS ADVANCES, 178.

By: C. Mora-Navarro n, E. Smith n, Z. Wang n, M. Ramos-Alamo*, L. Collins n, N. Awad*, D. Cruz*, T. Tollison n ...

co-author countries: Puerto Rico 🇵🇷
author keywords: Vocal fold lamina propria; Fibrosis; Extracellular matrix; Hydrogels; TGF-(31
topics (OpenAlex): Voice and Speech Disorders; Dysphagia Assessment and Management; Tissue Engineering and Regenerative Medicine
Sources: Web Of Science, NC State University Libraries
Added: August 25, 2025

2025 article

Temperature Programming Secondary Electrospray Ionization (TP-SESI): A Novel Approach for Mass Spectrometry Analysis of Plant Volatile Organic Compounds

Ashbacher, S. M., & Muddiman, D. C. (2025, July 30). ANALYTICAL CHEMISTRY, Vol. 7.

By: S. Ashbacher n & D. Muddiman n

topics (OpenAlex): Mass Spectrometry Techniques and Applications; Analytical Chemistry and Chromatography; Advanced Chemical Sensor Technologies
Sources: Web Of Science, NC State University Libraries
Added: August 11, 2025

2025 article

The Heme Oxygenase-Like Diiron Enzyme HrmI Reveals Altered Regulatory Mechanisms for Dioxygen Activation and Substrate N-Oxygenation

Skirboll, S. S., Gangopadhyay, M., Phan, H. N., Hartsell, J., Mudireddy, A., Hilovsky, D., … Makris, T. M. (2025, August 7). JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol. 8.

By: S. Skirboll n, M. Gangopadhyay*, H. Phan n, J. Hartsell n, A. Mudireddy n, D. Hilovsky n, P. Swartz n, X. Liu n, Y. Guo*, T. Makris n

topics (OpenAlex): Metal-Catalyzed Oxygenation Mechanisms; Porphyrin and Phthalocyanine Chemistry; Radioactive element chemistry and processing
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 8, 2025

2025 book

Preface

In Methods in Molecular Biology (Vol. 2884, pp. v-vii). http://www.scopus.com/inward/record.url?eid=2-s2.0-85217540581&partnerID=MN8TOARS

By: T. Williams

Contributors: T. Williams

Source: ORCID
Added: July 14, 2025

2025 journal article

Conditional knockout of C/EBPβ in epidermis results in dysregulated lipid biosynthesis and a defect in skin barrier function

PLOS ONE, 20(6).

By: K. Mills n, M. Doyle n, J. House n, J. Witherspoon n, D. Krakko n, W. Stutts n, J. Chappel n, J. Hall n, E. Baker n, R. Smart n

Ed(s): S. Raza

MeSH headings : Animals; Epidermis / metabolism; Mice; Mice, Knockout; Lipid Metabolism / genetics; Lipids / biosynthesis; CCAAT-Enhancer-Binding Proteins / genetics; CCAAT-Enhancer-Binding Proteins / metabolism; Keratinocytes / metabolism; Lipogenesis / genetics; Lipidomics
topics (OpenAlex): melanin and skin pigmentation; Retinoids in leukemia and cellular processes; Plant Molecular Biology Research
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 25, 2025

2025 article

Illuminating the mechanistic impacts of an Fe-quaterpyridine functionalized crystalline poly(triazine imide) semiconductor for photocatalytic CO<sub>2</sub> reduction

McGuigan, S., Tereniak, S. J., Smith, A., Jana, S., Donley, C. L., Collins, L., … Maggard, P. A. (2025, June 17). INORGANIC CHEMISTRY FRONTIERS, Vol. 6.

By: S. McGuigan*, S. Tereniak, A. Smith, S. Jana*, C. Donley, L. Collins*, N. Ghorai, Y. Xu ...

topics (OpenAlex): Covalent Organic Framework Applications; Advanced Photocatalysis Techniques; CO2 Reduction Techniques and Catalysts
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 25, 2025

2025 journal article

Mitochondrial Preparation from Microglia for Glycan Analysis

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 5(219).

By: M. Madabhushi, T. Palomino*, M. Patil, D. Muddiman*, D. Tyrrell & J. Samal

MeSH headings : Microglia / chemistry; Microglia / metabolism; Polysaccharides / analysis; Mitochondria / chemistry; Mitochondria / metabolism; Animals; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Mitochondrial Proteins / chemistry; Mitochondrial Proteins / analysis; Mitochondrial Proteins / isolation & purification; Mitochondrial Proteins / metabolism; Mice
topics (OpenAlex): Neuroinflammation and Neurodegeneration Mechanisms; Glycosylation and Glycoproteins Research; Neurological Disease Mechanisms and Treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 16, 2025

2025 article

Rab4a Drives Proinflammatory CD4+ T Cell Signaling via CD38-Dependent NAD+ Metabolism

Perl, A., Park, J., Krakko, D., Nolan, J., Wyman, B., & Sadeghzadeh, M. (2025, June 12).

topics (OpenAlex): Calcium signaling and nucleotide metabolism; Cellular transport and secretion; Adenosine and Purinergic Signaling
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: June 12, 2025

2025 article

Unraveling the molecular dynamics of wound healing: integrating spatially resolved lipidomics and temporally resolved proteomics

Bai, H., Arnedo, A. S., Liu, Y., Segura, T., & Muddiman, D. (2025, April 24). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 4.

By: H. Bai n, A. Arnedo*, Y. Liu*, T. Segura* & D. Muddiman n

author keywords: Wound healing; Mass spectrometry imaging; 3D; IR-MALDESI; Multi-omics
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Forensic Entomology and Diptera Studies; Spectroscopy Techniques in Biomedical and Chemical Research
Sources: Web Of Science, NC State University Libraries
Added: May 6, 2025

2025 journal article

Feasibility of IR-MALDESI Mass Spectrometry Imaging of PFAS

JOURNAL OF MASS SPECTROMETRY, 60(2).

author keywords: IR-MALDESI; LC-MS/MS; mass spectrometry imaging; PFAS; zebrafish
MeSH headings : Fluorocarbons / analysis; Animals; Mice; Limit of Detection; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Liver / chemistry; Liver / metabolism; Alkanesulfonic Acids / analysis; Caprylates / analysis; Feasibility Studies; Environmental Pollutants / analysis; Tandem Mass Spectrometry / methods; Zebrafish / metabolism
topics (OpenAlex): Per- and polyfluoroalkyl substances research; Lanthanide and Transition Metal Complexes; Mass Spectrometry Techniques and Applications
Sources: Web Of Science, NC State University Libraries
Added: April 28, 2025

2025 article

Distinguishing the Metabolic Effect of Fetal and Adult Fibrinogen on Human Fibroblast Cell Culture by IR-MALDESI Mass Spectrometry Imaging

Joignant, A. N., Sheridan, A., Brown, A. C., & Muddiman, D. C. (2025, April 7). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 4.

author keywords: IR-MALDESI; mass spectrometry imaging; fibroblast; fibrinogen
topics (OpenAlex): Blood properties and coagulation; Erythrocyte Function and Pathophysiology; Adipokines, Inflammation, and Metabolic Diseases
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 21, 2025

2025 article

Trophic Transfer of Perfluoroalkyl Acids in a Periphyton-Mayfly-Zebrafish Food Chain

Farrell, M. R., Buchwalter, D. B., Weed, R. A., Enders, J. R., & Planchart, A. J. (2025, April 15).

By: M. Farrell, D. Buchwalter*, R. Weed, J. Enders* & A. Planchart

topics (OpenAlex): Per- and polyfluoroalkyl substances research
Source: ORCID
Added: April 15, 2025

2025 article

Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Mass Spectrometry Imaging of Per- and Polyfluoroalkyl Substances (PFAS) in Stabilized Soil Cores

Guillette, T., Stutts, W., Baumeister, A., Liles, D., Olechiw, T., & Lang, J. (2025, March 18). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY.

By: T. Guillette*, W. Stutts n, A. Baumeister*, D. Liles*, T. Olechiw* & J. Lang*

topics (OpenAlex): Mass Spectrometry Techniques and Applications; Per- and polyfluoroalkyl substances research; Analytical Chemistry and Chromatography
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: March 31, 2025

2025 article

Detection and Quantitation of Per- and Polyfluoroalkyl Substances in Sea Foam and the Corresponding Sea Water

Enders, J., Weed, R., Donovan, E., Phelps, D., Campbell, G., May, K., & Baker, E. (2025, March 27).

By: J. Enders n, R. Weed n, E. Donovan, D. Phelps n, G. Campbell n, K. May n, E. Baker*

topics (OpenAlex): Per- and polyfluoroalkyl substances research; Toxic Organic Pollutants Impact
Source: ORCID
Added: March 27, 2025

2025 article

Topographic imaging with automatic z-axis correction of <i>Brassica oleracea</i> var. <i>viridis</i> leaves by IR-MALDESI mass spectrometry imaging

Mills, Q., Ashbacher, S. M., Sohn, A. L., & Muddiman, D. C. (2025, March 15). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 3.

By: Q. Mills n, S. Ashbacher n, A. Sohn n & D. Muddiman n

author keywords: IR-MALDESI; Mass spectrometry imaging; Plant imaging; Plant metabolomics; Plant biology; <italic>Brassica oleracea</italic> var. <italic>viridis</italic>
MeSH headings : Brassica / chemistry; Plant Leaves / chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Spectrometry, Mass, Electrospray Ionization / methods
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Metabolomics and Mass Spectrometry Studies; Analytical Chemistry and Chromatography
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 19, 2025

2025 article

Glycosaminoglycan Mass Spectrometry Imaging by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

Palomino, T. V., & Muddiman, D. C. (2025, March 4). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 3.

By: T. Palomino n & D. Muddiman n

author keywords: Chondroitin Sulfate; Glycosaminoglycans; MassSpectrometry Imaging; IR-MALDESI
MeSH headings : Animals; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Chondroitin Sulfates / analysis; Chondroitin Sulfates / chemistry; Spectrometry, Mass, Electrospray Ionization / methods; Brain Chemistry; Glycosaminoglycans / analysis; Glycosaminoglycans / chemistry; Rats; Disaccharides / analysis; Disaccharides / chemistry; Male; Mice; Brain / diagnostic imaging; Brain / metabolism
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Proteoglycans and glycosaminoglycans research; Analytical Chemistry and Chromatography
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: March 17, 2025

2025 article

Release of Per- and Polyfluoroalkyl Substances from Municipal and Construction and Demolition Waste Landfills and Wastewater Treatment Plants in North Carolina

Thelusmond, J.-R., Sardarmehni, M., Destefano, N., Weed, R., Knappe, D. R. U., & Barlaz, M. A. (2025, March 6). ACS ES&T WATER, Vol. 3.

By: J. Thelusmond n, M. Sardarmehni n, N. Destefano n, R. Weed n, D. Knappe n & M. Barlaz n

author keywords: landfill leachate; domesticwastewater; municipalsolid waste; perfluoroalkyl sulfonic acids; perfluoroalkylcarboxylic acids; fluorotelomer acids; per- andpolyfluoroalkyl ether acids
topics (OpenAlex): Per- and polyfluoroalkyl substances research; Toxic Organic Pollutants Impact; Atmospheric chemistry and aerosols
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 6, 2025

2025 journal article

Part A: Implementing an Analyte Panel and Sampling Protocol for Quality Control in Mass Spectrometry Imaging

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 39(8).

By: Q. Mills n, R. Kibbe n, A. Sohn n, A. Percy*, K. Backiel* & D. Muddiman n

author keywords: IR-MALDESI; mass spectrometry imaging; quality control; stable isotope labeled; system suitability testing
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Metabolomics and Mass Spectrometry Studies; Analytical Chemistry and Chromatography
Sources: Web Of Science, NC State University Libraries
Added: March 3, 2025

2025 journal article

Part B: SLICE-MSI-A Machine Learning Interface for System Suitability Testing of Mass Spectrometry Imaging Platforms

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 39(8).

By: R. Kibbe n, Q. Mills n, A. Sohn n & D. Muddiman n

author keywords: graphical user interface; machine learning; mass spectrometry imaging; quality control; system suitability testing
topics (OpenAlex): Machine Learning in Materials Science; Metabolomics and Mass Spectrometry Studies; Mass Spectrometry Techniques and Applications
Sources: Web Of Science, NC State University Libraries
Added: March 3, 2025

2025 journal article

Comparison of Mid-Infrared and Ultraviolet Lasers Coupled to the MALDESI Source for the Detection of Secondary Metabolites and Structural Lipids in <i>Arabidopsis thaliana</i>

JOURNAL OF MASS SPECTROMETRY, 60(3).

By: S. Ashbacher n, J. Manni & D. Muddiman n

author keywords: MALDESI; mass spectrometry imaging; mid-infrared; plants; ultraviolet
MeSH headings : Arabidopsis / chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Lasers; Ultraviolet Rays; Secondary Metabolism; Lipids / analysis; Lipids / chemistry; Flavonoids / analysis; Flavonoids / chemistry; Infrared Rays; Glucosinolates / analysis; Glucosinolates / chemistry; Plant Leaves / chemistry; Galactolipids / analysis; Galactolipids / chemistry; Fatty Acids / analysis; Fatty Acids / chemistry
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Analytical Chemistry and Chromatography; Metabolomics and Mass Spectrometry Studies
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 28, 2025

2025 article

Three-dimensional mass spectrometry imaging (3D MSI): incorporating top-hat IR-MALDESI and automatic <i>z</i>-axis correction

Sohn, A. L., Witherspoon, J. G., Smart, R. C., & Muddiman, D. C. (2025, February 3). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 2.

By: A. Sohn n, J. Witherspoon n, R. Smart n & D. Muddiman n

author keywords: 3D; Mass spectrometry imaging; Lipids; Automatic <italic>z</italic>-axis correction; Top-hat
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Analytical Chemistry and Chromatography; Metabolomics and Mass Spectrometry Studies
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 3, 2025

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