Molecular Education, Technology and Research Innovation Center

Recent Works

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Sorted by most recent date added to the index first, which may not be the same as publication date order.

2025 journal article

Historical Blood Serum Samples from Wilmington, North Carolina: The Importance of Ultrashort-Chain Per- and Polyfluoroalkyl Substances

Environmental Science & Technology.

By: L. Cheng, S. Teagle, J. Enders, R. Weed, H. Nichols, D. Knappe, J. Hoppin

topics (OpenAlex):
Source: ORCID
Added: October 27, 2025

2025 journal article

Phosphorylation of UDP-glucose dehydrogenase increases glycosaminoglycan biosynthesis and promotes tumor cell motility, spheroid growth, and therapeutic resistance

Matrix Biology.

By: A. Utz, L. Ma, D. Hilovsky, B. Zimmer, E. Allego, J. Fluharty, P. Narasimhan, J. Enders ...

topics (OpenAlex):
Source: ORCID
Added: October 17, 2025

2025 journal article

A Strategy to Achieve Sub-Parts-per-Million Mass Measurement Accuracy of <i>N</i>-Linked Glycans Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

JOURNAL OF MASS SPECTROMETRY, 60(10).

author keywords: custom calibration; IR-MALDESI; mass calibration; mass measurement accuracy; N-linked glycans
MeSH headings : Polysaccharides / chemistry; Polysaccharides / analysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Animals; Cattle; Calibration; Spectrometry, Mass, Electrospray Ionization / methods; Fetuins / chemistry
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Glycosylation and Glycoproteins Research; Analytical Chemistry and Chromatography
Source: Web Of Science
Added: October 13, 2025

2025 article

Demonstrating voxel-by-voxel (V x V) single-point calibration in liver tissue by IR-MALDESI quantitative MSI

Bruce, E. R., Kibbe, R. R., Opperman, L. J., & Muddiman, D. C. (2025, September 29). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 9.

author keywords: IR-MALDESI; Quantitative mass spectrometry imaging; Single-point calibration; Quantitative sampling
topics (OpenAlex):
Sources: Web Of Science, NC State University Libraries
Added: October 7, 2025

2025 journal article

Trophic transfer of per- and polyfluoroalkyl acids in a periphyton-mayfly-zebrafish food chain

AQUATIC TOXICOLOGY, 287.

By: M. Farrell n, D. Buchwalter n, R. Weed n, J. Enders n & A. Planchart n

author keywords: PFAS; Trophic; Bioaccumulation; Zebrafish; Invertebrate; Biofilm; Freshwater
MeSH headings : Animals; Food Chain; Water Pollutants, Chemical / metabolism; Water Pollutants, Chemical / analysis; Zebrafish / metabolism; Larva / metabolism; Fluorocarbons / metabolism; Fluorocarbons / analysis; Periphyton; Ephemeroptera / metabolism
topics (OpenAlex): Per- and polyfluoroalkyl substances research; Toxic Organic Pollutants Impact; Atmospheric chemistry and aerosols
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 7, 2025

2025 journal article

Comparative proteomic analysis of skin wound healing responses to biomaterial treatments identifies key pathways which govern differential regenerative outcomes

BIOMATERIALS, 326.

author keywords: Proteomics; Gene ontology; MAP scaffold; Chirality; Regeneration; Wound healing
topics (OpenAlex): Wound Healing and Treatments; Tendon Structure and Treatment; Periodontal Regeneration and Treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 29, 2025

2025 article

Structural features of 11 synthetic bacteriochlorins - comparisons with chlorins and porphyrins

Tran, V.-P., Taniguchi, M., Sommer, R. D., Boyle, P. D., Nalaoh, P., & Lindsey, J. S. (2025, September 9). JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, Vol. 9.

author keywords: bacteriochlorin; distortion; hydroporphyrin; space group; unit cell; X-ray diffraction
topics (OpenAlex): Porphyrin and Phthalocyanine Chemistry; Photodynamic Therapy Research Studies; Porphyrin Metabolism and Disorders
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 15, 2025

2025 journal article

A versatile and efficient method to quantify purity and degree of substitution in alginate derivatives

Carbohydrate Polymers.

topics (OpenAlex): 3D Printing in Biomedical Research; Hydrogels: synthesis, properties, applications; Biopolymer Synthesis and Applications
Source: ORCID
Added: September 2, 2025

2025 article

Recent insights into the implications of UGDH mutations for human developmental disease

Harwood, H., Zimmer, B. M., Utz, A. R., Barycki, J. J., & Simpson, M. A. (2025, August 28). BIOCHEMICAL SOCIETY TRANSACTIONS, Vol. 8.

By: H. Harwood, B. Zimmer, A. Utz, J. Barycki & M. Simpson

MeSH headings : Humans; Mutation; Uridine Diphosphate Glucose Dehydrogenase / genetics; Uridine Diphosphate Glucose Dehydrogenase / metabolism; Animals; Congenital Disorders of Glycosylation / genetics
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 29, 2025

2025 article

Detection and Quantitation of Per- and Polyfluoroalkyl Substances in North Carolina Sea Foam and the Corresponding Sea Water

Enders, J. R., Weed, R. A., Donovan, E., Phelps, D., Campbell, G., May, K., & Baker, E. S. (2025, August 27). ENVIRONMENTAL SCIENCE & TECHNOLOGY, Vol. 8.

By: J. Enders, R. Weed, E. Donovan, D. Phelps, G. Campbell, K. May, E. Baker

author keywords: PFAS contamination; sea foam accumulation; high-resolution mass spectrometry (HRMS); quantitative analysis; nontargeted analysis; per- and polyfluoroalkyl substances(PFAS); emerging PFAS compounds
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 27, 2025

2025 article

Characterization of an isobutylene epoxide hydrolase (IbcK) from the isobutylene-catabolizing bacterium <i>Mycolicibacterium</i> sp. ELW1

Faulkner, N. W., Joyce, J. B., Smith, C., Swartz, P., Rose, R. B., Miller, E. S., & Hyman, M. R. (2025, August 26). (M. Vives, Ed.). APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol. 8.

By: N. Faulkner, J. Joyce, C. Smith, P. Swartz, R. Rose, E. Miller, M. Hyman

Ed(s): M. Vives

author keywords: epoxide hydrolase; isobutylene; isobutylene oxide; MTBE; alkenes; bioremediation
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 26, 2025

2025 article

Mechanistic Insights into Visible-Light-Induced ATRA Reactions Powered by the Symbiotic Relationship between Cu(II)/Cu(I) Phenanthroline Complexes

Arteta, S., Deegbey, M., Durand, N., Kibbe, R., Floss, J., Barth, A. T., … Castellano, F. N. (2025, August 26). ACS CATALYSIS, Vol. 8.

author keywords: photochemistry; photocatalysts; charge transfer; copper phenanthrolines; ATRA reactions
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 26, 2025

2025 journal article

Injection of vocal fold lamina propria-derived hydrogels modulates fibrosis in injured vocal folds

BIOMATERIALS ADVANCES, 178.

By: C. Mora-Navarro n, E. Smith n, Z. Wang n, M. Ramos-Alamo*, L. Collins n, N. Awad*, D. Cruz*, T. Tollison n ...

co-author countries: Puerto Rico 🇵🇷
author keywords: Vocal fold lamina propria; Fibrosis; Extracellular matrix; Hydrogels; TGF-(31
topics (OpenAlex): Voice and Speech Disorders; Dysphagia Assessment and Management; Tissue Engineering and Regenerative Medicine
Sources: Web Of Science, NC State University Libraries
Added: August 25, 2025

2025 article

Temperature Programming Secondary Electrospray Ionization (TP-SESI): A Novel Approach for Mass Spectrometry Analysis of Plant Volatile Organic Compounds

Ashbacher, S. M., & Muddiman, D. C. (2025, July 30). ANALYTICAL CHEMISTRY, Vol. 7.

By: S. Ashbacher n & D. Muddiman n

topics (OpenAlex): Mass Spectrometry Techniques and Applications; Analytical Chemistry and Chromatography; Advanced Chemical Sensor Technologies
Sources: Web Of Science, NC State University Libraries
Added: August 11, 2025

2025 article

The Heme Oxygenase-Like Diiron Enzyme HrmI Reveals Altered Regulatory Mechanisms for Dioxygen Activation and Substrate N-Oxygenation

Skirboll, S. S., Gangopadhyay, M., Phan, H. N., Hartsell, J., Mudireddy, A., Hilovsky, D., … Makris, T. M. (2025, August 7). JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol. 8.

By: S. Skirboll n, M. Gangopadhyay*, H. Phan n, J. Hartsell n, A. Mudireddy n, D. Hilovsky n, P. Swartz n, X. Liu n, Y. Guo*, T. Makris n

topics (OpenAlex): Metal-Catalyzed Oxygenation Mechanisms; Porphyrin and Phthalocyanine Chemistry; Radioactive element chemistry and processing
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 8, 2025

2025 book

Preface

In Methods in Molecular Biology (Vol. 2884, pp. v-vii). http://www.scopus.com/inward/record.url?eid=2-s2.0-85217540581&partnerID=MN8TOARS

By: T. Williams

Contributors: T. Williams

Source: ORCID
Added: July 14, 2025

2025 journal article

Conditional knockout of C/EBPβ in epidermis results in dysregulated lipid biosynthesis and a defect in skin barrier function

PLOS ONE, 20(6).

By: K. Mills n, M. Doyle n, J. House n, J. Witherspoon n, D. Krakko n, W. Stutts n, J. Chappel n, J. Hall n, E. Baker n, R. Smart n

Ed(s): S. Raza

MeSH headings : Animals; Epidermis / metabolism; Mice; Mice, Knockout; Lipid Metabolism / genetics; Lipids / biosynthesis; CCAAT-Enhancer-Binding Proteins / genetics; CCAAT-Enhancer-Binding Proteins / metabolism; Keratinocytes / metabolism; Lipogenesis / genetics; Lipidomics
topics (OpenAlex): melanin and skin pigmentation; Retinoids in leukemia and cellular processes; Plant Molecular Biology Research
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 25, 2025

2025 article

Illuminating the mechanistic impacts of an Fe-quaterpyridine functionalized crystalline poly(triazine imide) semiconductor for photocatalytic CO<sub>2</sub> reduction

McGuigan, S., Tereniak, S. J., Smith, A., Jana, S., Donley, C. L., Collins, L., … Maggard, P. A. (2025, June 17). INORGANIC CHEMISTRY FRONTIERS, Vol. 6.

By: S. McGuigan*, S. Tereniak, A. Smith, S. Jana*, C. Donley, L. Collins*, N. Ghorai, Y. Xu ...

topics (OpenAlex): Covalent Organic Framework Applications; Advanced Photocatalysis Techniques; CO2 Reduction Techniques and Catalysts
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 25, 2025

2025 journal article

Mitochondrial Preparation from Microglia for Glycan Analysis

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 5(219).

MeSH headings : Microglia / chemistry; Microglia / metabolism; Polysaccharides / analysis; Mitochondria / chemistry; Mitochondria / metabolism; Animals; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Mitochondrial Proteins / chemistry; Mitochondrial Proteins / analysis; Mitochondrial Proteins / isolation & purification; Mitochondrial Proteins / metabolism; Mice
topics (OpenAlex): Neuroinflammation and Neurodegeneration Mechanisms; Glycosylation and Glycoproteins Research; Neurological Disease Mechanisms and Treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 16, 2025

2025 article

Rab4a Drives Proinflammatory CD4+ T Cell Signaling via CD38-Dependent NAD+ Metabolism

Perl, A., Park, J., Krakko, D., Nolan, J., Wyman, B., & Sadeghzadeh, M. (2025, June 12).

topics (OpenAlex): Calcium signaling and nucleotide metabolism; Cellular transport and secretion; Adenosine and Purinergic Signaling
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: June 12, 2025

2025 article

Unraveling the molecular dynamics of wound healing: integrating spatially resolved lipidomics and temporally resolved proteomics

Bai, H., Arnedo, A. S., Liu, Y., Segura, T., & Muddiman, D. (2025, April 24). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 4.

By: H. Bai n, A. Arnedo*, Y. Liu*, T. Segura* & D. Muddiman n

author keywords: Wound healing; Mass spectrometry imaging; 3D; IR-MALDESI; Multi-omics
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Forensic Entomology and Diptera Studies; Spectroscopy Techniques in Biomedical and Chemical Research
Sources: Web Of Science, NC State University Libraries
Added: May 6, 2025

2025 journal article

Feasibility of IR-MALDESI Mass Spectrometry Imaging of PFAS

JOURNAL OF MASS SPECTROMETRY, 60(2).

author keywords: IR-MALDESI; LC-MS/MS; mass spectrometry imaging; PFAS; zebrafish
MeSH headings : Fluorocarbons / analysis; Animals; Mice; Limit of Detection; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Liver / chemistry; Liver / metabolism; Alkanesulfonic Acids / analysis; Caprylates / analysis; Feasibility Studies; Environmental Pollutants / analysis; Tandem Mass Spectrometry / methods; Zebrafish / metabolism
topics (OpenAlex): Per- and polyfluoroalkyl substances research; Lanthanide and Transition Metal Complexes; Mass Spectrometry Techniques and Applications
Sources: Web Of Science, NC State University Libraries
Added: April 28, 2025

2025 article

Distinguishing the Metabolic Effect of Fetal and Adult Fibrinogen on Human Fibroblast Cell Culture by IR-MALDESI Mass Spectrometry Imaging

Joignant, A. N., Sheridan, A., Brown, A. C., & Muddiman, D. C. (2025, April 7). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 4.

author keywords: IR-MALDESI; mass spectrometry imaging; fibroblast; fibrinogen
topics (OpenAlex): Blood properties and coagulation; Erythrocyte Function and Pathophysiology; Adipokines, Inflammation, and Metabolic Diseases
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 21, 2025

2025 article

Trophic Transfer of Perfluoroalkyl Acids in a Periphyton-Mayfly-Zebrafish Food Chain

Farrell, M. R., Buchwalter, D. B., Weed, R. A., Enders, J. R., & Planchart, A. J. (2025, April 15).

By: M. Farrell, D. Buchwalter*, R. Weed, J. Enders* & A. Planchart

topics (OpenAlex): Per- and polyfluoroalkyl substances research
Source: ORCID
Added: April 15, 2025

2025 article

Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Mass Spectrometry Imaging of Per- and Polyfluoroalkyl Substances (PFAS) in Stabilized Soil Cores

Guillette, T., Stutts, W., Baumeister, A., Liles, D., Olechiw, T., & Lang, J. (2025, March 18). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY.

By: T. Guillette*, W. Stutts n, A. Baumeister*, D. Liles*, T. Olechiw* & J. Lang*

topics (OpenAlex): Mass Spectrometry Techniques and Applications; Per- and polyfluoroalkyl substances research; Analytical Chemistry and Chromatography
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: March 31, 2025

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