Works Published in 1999
Displaying all 7 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
1999 journal article
Quantification of singly charged biomolecules by electrospray ionization fourier transform ion cyclotron resonance mass spectrometry utilizing an internal standard
Rapid Communications in Mass Spectrometry, 13(3), 164–171.
Sources: Crossref, ORCID
Added: February 27, 2021
1999 journal article
Hemoglobinase Activity of the Lysine Gingipain Protease (Kgp) of Porphyromonas gingivalis W83
Journal of Bacteriology, 181(16), 4905–4913.
MeSH headings : Adhesins, Bacterial; Agar; Amino Acid Sequence; Blood; Chromatography; Chromosome Mapping; Cysteine Endopeptidases / genetics; Cysteine Endopeptidases / isolation & purification; Cysteine Endopeptidases / metabolism; Enzyme Activation / drug effects; Enzyme Inhibitors / pharmacology; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Gingipain Cysteine Endopeptidases; Helminth Proteins; Hemagglutinins / genetics; Hemagglutinins / isolation & purification; Hemagglutinins / metabolism; Heme / metabolism; Hemin / pharmacology; Hemoglobins / analysis; Hemoglobins / chemistry; Hemolysis; Humans; Imidazoles / pharmacology; Iron / metabolism; Mass Spectrometry; Membrane Proteins / metabolism; Molecular Sequence Data; Mutagenesis; Peptide Fragments / analysis; Peptide Fragments / chemistry; Porphyromonas gingivalis / enzymology; Porphyromonas gingivalis / genetics; Porphyromonas gingivalis / growth & development
TL;DR:
The ability of the Lys-gingipain to cleave human hemoglobin at Lys residues was confirmed by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry of hemoglobin fragments resulting from digestion with the purified protease, and several of the predicted Hemoglobin fragments rendered by digestion with purified Lys-gesipain were detected.
(via Semantic Scholar)
jb.asm.org (publisher PDF)
Sources: Crossref, ORCID
Added: February 12, 2021
1999 journal article
Consequences of Nucleic Acid Conformation on the Binding of a Trinuclear Platinum Drug†
Biochemistry, 38(45), 14731–14737.
MeSH headings : Antineoplastic Agents / metabolism; DNA / metabolism; DNA, Single-Stranded / metabolism; Mass Spectrometry; Nucleic Acid Conformation; Organoplatinum Compounds / metabolism; RNA / metabolism; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship
TL;DR:
BBR3464 binding to different nucleic acid conformations raises the possibility that the adducts of single-stranded DNA and RNA may play a role in the different antitumor efficacies of this novel drug as compared with cisplatin.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021
1999 journal article
Hydropathic influences on the quantification of equine heart cytochromec using relative ion abundance measurements by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry
Journal of Mass Spectrometry, 34(10), 1055–1062.
author keywords: proteomics; quantification; hydropathy; electrospray ionization; Fourier transform ion cyclotron resonance mass spectrometry
TL;DR:
The results present significant considerations when choosing internal standards for the quantification of large proteins by ESI-FTICR-MS and demonstrate that relative molecular ion signals in FTICR can be used to quantify macromolecular species in the nanomolar regime.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021
1999 journal article
Precise mass measurement of a double-stranded 500 base-pair (309 kDa) polymerase chain reaction product by negative ion electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry
Rapid Communications in Mass Spectrometry, 13(12), 1201–1204.
TL;DR:
It is demonstrated that precise mass measurements of PCR products up to 309 kDa (500 bp) can be routinely obtained by ESI-FTICR requiring low femtomole amounts.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021
1999 journal article
Accurate characterization of the tyrosine hydroxylase forensic allele 9.3 through development of electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry
Rapid Communications in Mass Spectrometry, 13(10), 954–962.
TL;DR:
The results indicate that ESI-FTICR-MS is a powerful approach to rapidly and accurately characterize tandem repeating sequences which will ultimately lead towards the understanding of a complex class of diseases and in human identity determination.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021
1999 journal article
Characterization of a microdialysis approach to prepare polymerase chain reaction products for electrospray ionization mass spectrometry using on-line ultraviolet absorbance measurements and inductively coupled plasma-atomic emission spectroscopy
Rapid Communications in Mass Spectrometry, 13(5), 323–330.
TL;DR:
The desalting efficiencies for microdialysis have been quantitatively determined using inductively coupled plasma atomic emission spectroscopy (ICP-AES) by analyzing samples which mimic polymerase chain reaction (PCR) conditions and revealed an insensitivity to molecular weight over a broad range.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, ORCID
Added: February 12, 2021
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