Works Published in 2001
Displaying all 10 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2001 journal article
Proton affinity of deuterated acetonitrile estimated by the kinetic method with full entropy analysis
International Journal of Mass Spectrometry, 210(211), 133–146.
Contributors: T. Williams* , J. Denault* & R. Cooks *
author keywords: proton affinity; kinetic method; entropy analysis; kinetic isotope effect; nitrites
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: April 8, 2021
2001 journal article
Perspectives on the use of electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry for short tandem repeat genotyping in the post‐genome era
Journal of Mass Spectrometry (Special Feature), 36(6), 589–606.
author keywords: electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry; short tandem repeats; genotyping; DNA; human genome
MeSH headings : Alleles; Animals; Cyclotrons; Fourier Analysis; Genetic Markers; Genotype; Humans; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Mass, Electrospray Ionization; Tandem Repeat Sequences / genetics
TL;DR:
This perspective is intended to familiarize the mass spectrometry community with modern genomics and to report on the current state of mass Spectrometry, specifically electrospray ionization Fourier transform ion cyclotron resonance mass spectromaetry, for characterization of STRs.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: March 17, 2021
2001 journal article
Homogeneous Preparations of 3′-Phosphoglycolate-Terminated Oligodeoxynucleotides from Bleomycin-Treated DNA as Verified by Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Analytical Biochemistry, 289(2), 274–280.
MeSH headings : Alkaline Phosphatase / pharmacology; Antimetabolites, Antineoplastic / pharmacology; Bleomycin / pharmacology; Chromatography, High Pressure Liquid; DNA / drug effects; DNA Damage / drug effects; DNA Repair; Electrophoresis, Polyacrylamide Gel; Glycolates / metabolism; Mass Spectrometry; Oligonucleotides / metabolism; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Time Factors
TL;DR:
Single- and double-strand breaks bearing 3'-phosphoglycolate termini are among the most frequent lesions formed in DNA by ionizing radiation and other oxidative mutagens and could be relabeled with polynucleotide kinase to yield highly purified, high-specific-activity substrates for repair studies.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 27, 2021
2001 journal article
Genotyping of Simple and Compound Short Tandem Repeat Loci Using Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Analytical Chemistry, 73(18), 4514–4521.
MeSH headings : Cyclotrons; Genotype; Humans; Microsatellite Repeats; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR:
The utility of electrospray ionization Fourier transform ion cyclotron resonance (ESI-FIICR) mass spectrometry as a new approach for genotyping short tandem repeats (STRs) is demonstrated and is a powerful approach to characterize both simple and compound STRs beyond the capabilities of electrophoretic technologies.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021
2001 journal article
Selective, Sensitive, and Rapid Phosphopeptide Identification in Enzymatic Digests Using ESI-FTICR-MS with Infrared Multiphoton Dissociation
Analytical Chemistry, 73(14), 3305–3311.
MeSH headings : Amino Acid Sequence; Animals; Caseins / analysis; Cattle; Fourier Analysis; Infrared Rays; Molecular Sequence Data; Phosphopeptides / analysis; Receptor, Insulin / analysis; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR:
The sensitivity and selectivity of phosphopeptides is shown to greatly improve when the volatile base piperidine is used to adjust the pH of the digestion of naturally phosphorylated proteins bovine alpha- and beta-casein.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021
2001 journal article
Complete sequencing of mono—deprotonated peptide nucleic acids by sustained off-resonance irradiation collision—induced dissociation
Journal of the American Society for Mass Spectrometry, 12(7), 805–809.
MeSH headings : Calibration; Chemical Phenomena; Chemistry, Physical; Mass Spectrometry; Peptide Nucleic Acids / chemistry; Sequence Analysis, DNA
TL;DR:
Complete peptide nucleic acids (PNAs) sequence information is obtained from the unimolecular decomposition of singly-charged PNA oligomers in the negative-ion mode using electrospray ionization coupled with Fourier transform ion cyclotron resonance mass spectrometry and sustained off-resonance irradiation collision induced dissociation.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021
2001 journal article
High-Mass Accuracy of Product Ions Produced by SORI-CID Using a Dual Electrospray Ionization Source Coupled with FTICR Mass Spectrometry
Analytical Chemistry, 73(6), 1247–1251.
MeSH headings : Cyclotrons; Fourier Analysis; Oligonucleotides / analysis; Spectrometry, Mass, Electrospray Ionization
TL;DR:
This internal standardization method demonstrated significantly more consistent accurate mass measurements with average mass errors ranging from -1.2 to -3.2 ppm for the 15-mer oligonucleotide used in this study.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021
2001 journal article
Genotyping short tandem repeats using flow injection and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry
Rapid Communications in Mass Spectrometry, 15(5), 348–350.
MeSH headings : Alleles; Cyclotrons; Flow Injection Analysis; Fourier Analysis; Genotype; Homozygote; Polymerase Chain Reaction; Spectrometry, Mass, Electrospray Ionization; Tandem Repeat Sequences
TL;DR:
Characterizing polymerase chain reaction (PCR) amplicons has been accomplished for the first time using flow injection analysis coupled to electrospray ionization mass spectrometry (ESI-MS) to illustrate the compatibility of ESI-MS for genotyping short tandem repeat sequences and the potential for high-throughput genotypesing of large PCR amplicons.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021
2001 journal article
Detection of double-stranded PCR amplicons at the attomole level electrosprayed from low nanomolar solutions using FT-ICR mass spectrometry
Fresenius' Journal of Analytical Chemistry, 369(3-4), 246–251.
MeSH headings : Alleles; Cyclotrons; DNA / chemistry; DNA / genetics; Fourier Analysis; Homozygote; Humans; Mass Spectrometry / methods; Polymerase Chain Reaction / methods; Sensitivity and Specificity; Solutions; Spectrometry, Mass, Electrospray Ionization / methods; Spectrophotometry / methods
TL;DR:
A remarkable sensitivity for large PCR amplicons will dramatically improve the ability of electrospray ionization mass spectrometry to address important genetic questions for low copy number genes or when the amount of initial template is limited; the latter issue is commonly encountered in DNA forensics.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021
2001 journal article
Impact of ion cloud densities on the measurement of relative ion abundances in Fourier transform ion cyclotron resonance mass spectrometry: experimental observations of coulombically induced cyclotron radius perturbations and ion cloud dephasing rates
Journal of Mass Spectrometry, 36(2), 195–203.
author keywords: space-charge; ion cloud density; signal decay; proteomics; quantification
MeSH headings : Cyclosporine / chemistry; Ions; Spectroscopy, Fourier Transform Infrared
TL;DR:
Experimental evidence supports that it is the loss of cloud coherence that accounts for the signal loss over time, with the less dense cloud de-phasing more quickly, as the ion populations of the two investigated species near equivalence, so do their time constants.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021
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