Works Published in 2014
Displaying works 1 - 20 of 47 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 speech
Quantitative Analysis using Rapid Technologies
(2014, October). In Rapid Urine Drug Testing by Mass Spectrometry. Workshop presented at the Society of Forensic Toxicology (SOFT) Annual Meeting, Grand Rapids, MI.
Event: Society of Forensic Toxicology (SOFT) Annual Meeting at Grand Rapids, MI
Source: NC State University Libraries
Added: March 12, 2022
2014 conference paper
Oral Fluid Testing for Opiates by Dilute and Shoot LC-MS/MS
Presented at the Society of Forensic Toxicology (SOFT) Annual Meeting, Grand Rapids, MI.
Event: Society of Forensic Toxicology (SOFT) Annual Meeting at Grand Rapids, MI
Source: NC State University Libraries
Added: March 12, 2022
2014 conference paper
Cross-Platform Comparison of Rapid Benzodiazepine Analyses
Presented at the Society of Forensic Toxicology (SOFT) Annual Meeting, Grand Rapids, MI.
Event: Society of Forensic Toxicology (SOFT) Annual Meeting at Grand Rapids, MI
Source: NC State University Libraries
Added: March 12, 2022
2014 conference paper
Oral Fluid Testing for Buprenorphine and THC by "Dilute and Shoot LC-MS/MS
Presented at the 62nd American Society for Mass Spectrometry (ASMS) Annual Conference, Baltimore, MD.
Event: 62nd American Society for Mass Spectrometry (ASMS) Annual Conference at Baltimore, MD
Source: NC State University Libraries
Added: March 12, 2022
2014 conference paper
Rapid Analysis of Selected Benzodiazepines by Automated SPE/MS/MS
Presented at the Association for Mass Spectrometry Applications to the Clinical Lab (MSACL) Annual Conference, San Diego, CA.
Event: Association for Mass Spectrometry Applications to the Clinical Lab (MSACL) Annual Conference at San Diego, CA
Source: NC State University Libraries
Added: March 12, 2022
2014 conference paper
Easy to Automate Extraction of THC Metabolites for LC-MS/MS Analysis
Presented at the Association for Mass Spectrometry Applications to the Clinical Lab (MSACL) Annual Conference, San Diego, CA.
Event: Association for Mass Spectrometry Applications to the Clinical Lab (MSACL) Annual Conference at San Diego, CA
Source: NC State University Libraries
Added: March 12, 2022
2014 conference paper
Oral Fluid Pain Management Panel by "Dilute and Shoot" LC-MS/MS
Presented at the Association for Mass Spectrometry Applications to the Clinical Lab (MSACL) Annual Conference, San Diego, CA.
Event: Association for Mass Spectrometry Applications to the Clinical Lab (MSACL) Annual Conference at San Diego, CA
Source: NC State University Libraries
Added: March 12, 2022
2014 journal article
Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication
Scientific Reports, 4(1).
MeSH headings : 5-Methylcytosine / metabolism; Base Pairing / genetics; Cell Proliferation / genetics; Cytosine / analogs & derivatives; Cytosine / metabolism; DNA / genetics; DNA Mismatch Repair / genetics; DNA Replication / genetics; Epigenesis, Genetic / genetics; Guanine / metabolism; Humans; Thymine DNA Glycosylase / metabolism
TL;DR:
It is shown that although 5caC pairs with guanine during DNA replication in vitro, G·5caC Pair stimulated DNA polymerase exonuclease activity and were recognized by the mismatch repair (MMR) proteins, indicating MMR is a novel reader for 5CAC.
(via Semantic Scholar)
www.nature.com (publisher PDF)
Sources: Crossref, NC State University Libraries
Added: September 5, 2021
2014 journal article
Molecular Dosimetry of Endogenous and Exogenous O6-Methyl-dG and N7-Methyl-G Adducts Following Low Dose [D3]-Methylnitrosourea Exposures in Cultured Human Cells
Chemical Research in Toxicology, 27(4), 480–482.
MeSH headings : Cells, Cultured; Deoxyguanosine / analogs & derivatives; Deoxyguanosine / metabolism; Dose-Response Relationship, Drug; Guanine / analogs & derivatives; Guanine / metabolism; Humans; Methylnitrosourea / administration & dosage; Methylnitrosourea / pharmacology
TL;DR:
The data show that O6-methyl-dG adducts ≥1.8/108 dG correlated with published studies that demonstrated significant increases of mutations under these conditions, but the combined results do not support linear extrapolations to zero when data are available for science-based regulations.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 5, 2021
2014 journal article
The endogenous exposome
DNA Repair, 19, 3–13.
author keywords: Endogenous exposome; DNA damage; Stable isotopes; Mutagenesis; Risk assessment
MeSH headings : Animals; Antioxidant Response Elements / genetics; DNA Adducts / drug effects; DNA Adducts / genetics; DNA Damage / drug effects; DNA Damage / genetics; Dose-Response Relationship, Drug; Isotope Labeling; Mutagenesis / drug effects; Mutagenesis / genetics
TL;DR:
This review has focused on the endogenous exposome, the DNA damage that arises from the production of endogenous electrophilic molecules in the authors' cells, and provides quantitative data on endogenous DNA damage and its relationship to mutagenesis, with emphasis on when exogenous chemical exposures that produce identical DNA adducts to those arising from normal metabolism cause significant increases in total identical DNAAdducts.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 5, 2021
2014 journal article
A Gnotobiotic Mouse Model Demonstrates That Dietary Fiber Protects against Colorectal Tumorigenesis in a Microbiota- and Butyrate-Dependent Manner
Cancer Discovery, 4(12), 1387–1397.
MeSH headings : Animals; Butyrates / metabolism; Carcinogens / administration & dosage; Cell Transformation, Neoplastic; Colorectal Neoplasms / etiology; Colorectal Neoplasms / pathology; Dietary Fiber; Disease Models, Animal; Germ-Free Life; Humans; Intestinal Mucosa / pathology; Mice; Microbiota; Neoplasm Grading
TL;DR:
The results, which link diet and microbiota to a tumor-suppressive metabolite, provide insight into conflicting epidemiologic findings and suggest that probiotic/prebiotic strategies can modulate an endogenous HDAC inhibitor for anticancer chemoprevention without the adverse effects associated with synthetic HDAC inhibitors used in chemotherapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 5, 2021
2014 journal article
Comparative Analysis of the Relationship Between Trichloroethylene Metabolism and Tissue-Specific Toxicity Among Inbred Mouse Strains: Kidney Effects
Journal of Toxicology and Environmental Health, Part A, 78(1), 32–49.
MeSH headings : Animals; Carcinogens / pharmacokinetics; Carcinogens / toxicity; Cell Proliferation / drug effects; Cysteine / analogs & derivatives; Cysteine / metabolism; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Dichloroacetic Acid / metabolism; Ethylene Chlorohydrin / analogs & derivatives; Ethylene Chlorohydrin / metabolism; Glutathione / analogs & derivatives; Glutathione / metabolism; Hepatitis A Virus Cellular Receptor 1; Kidney / cytology; Kidney / drug effects; Kidney / metabolism; Male; Membrane Proteins / genetics; Membrane Proteins / metabolism; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction / drug effects; PPAR alpha / genetics; PPAR alpha / metabolism; Trichloroacetic Acid / metabolism; Trichloroethylene / pharmacokinetics; Trichloroethylene / toxicity
TL;DR:
Overall, data demonstrated that renal TCE metabolite levels are associated with kidney-specific toxicity and that these effects are strain dependent.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 5, 2021
2014 journal article
Comparative Analysis of the Relationship Between Trichloroethylene Metabolism and Tissue-Specific Toxicity Among Inbred Mouse Strains: Liver Effects
Journal of Toxicology and Environmental Health, Part A, 78(1), 15–31.
MeSH headings : Administration, Oral; Animals; Carcinogens / pharmacokinetics; Carcinogens / toxicity; Cell Proliferation; Cysteine / analogs & derivatives; Cysteine / blood; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Dichloroacetic Acid / blood; Dose-Response Relationship, Drug; Ethylene Chlorohydrin / analogs & derivatives; Ethylene Chlorohydrin / metabolism; Gene Expression; Glutathione / analogs & derivatives; Glutathione / blood; Hepatocytes / drug effects; Hepatocytes / metabolism; Liver / cytology; Liver / drug effects; Liver / metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction / drug effects; Oxidative Stress / drug effects; Real-Time Polymerase Chain Reaction; Solvents / pharmacokinetics; Solvents / toxicity; Trichloroacetic Acid / blood; Trichloroethylene / pharmacokinetics; Trichloroethylene / toxicity
TL;DR:
A hypothesis was tested that amounts of oxidative metabolites of TCE in mouse liver are associated with hepatic-specific toxicity, and the magnitude of induction of peroxisome proliferator-marker genes declined, but hepatocellular proliferation increased.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 5, 2021
2014 chapter
Atmospheric Pressure Mass Spectrometry Imaging
In R. A. Meyers (Ed.), Encyclopedia of Analytical Chemistry: Applications, Theory and Instrumentation (pp. 1–44).
Ed(s): R. Meyers
Sources: NC State University Libraries, NC State University Libraries
Added: March 8, 2021
2014 journal article
C/EBPα regulates CRL4Cdt2-mediated degradation of p21 in response to UVB-induced DNA damage to control the G1/S checkpoint
Cell Cycle, 13(22), 3602–3610.
author keywords: C/EBP alpha; CRL4(Cdt2); G(1)/S DNA damage checkpoint; keratinocytes; p21
MeSH headings : Animals; CCAAT-Enhancer-Binding Protein-alpha / genetics; CCAAT-Enhancer-Binding Protein-alpha / metabolism; Cell Cycle Checkpoints / genetics; Cell Cycle Checkpoints / radiation effects; Cyclin-Dependent Kinase Inhibitor p21 / metabolism; DNA Damage / genetics; DNA Damage / radiation effects; G1 Phase Cell Cycle Checkpoints / genetics; Keratinocytes / metabolism; Keratinocytes / radiation effects; Mice; Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Proteolysis; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism; Ultraviolet Rays; p21-Activated Kinases / genetics; p21-Activated Kinases / metabolism
TL;DR:
Findings reveal C/EBPα regulates G1/S cell cycle arrest in response to DNA damage via the control of CRL4Cdt2 mediated degradation of p21.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 27, 2021
2014 journal article
Systems Biology of Lignin Biosynthesis in Populus trichocarpa: Heteromeric 4-Coumaric Acid:Coenzyme A Ligase Protein Complex Formation, Regulation, and Numerical Modeling
The Plant Cell, 26(3), 876–893.
MeSH headings : Coenzyme A Ligases / genetics; Coenzyme A Ligases / metabolism; Coumaric Acids / metabolism; Immunoprecipitation; Lignin / biosynthesis; Mass Spectrometry; Models, Biological; Populus / metabolism; Propionates; RNA, Messenger / genetics; Substrate Specificity; Systems Biology
TL;DR:
This work shows that 4CL, an enzyme in monolignol biosynthesis, is found as a heterotetrameric complex of two isoforms in Populus trichocarpa, where the two 4-coumaric acid:CoA ligase (4CL) isoforms, 4CL3 and 4CL5, interact in vivo and in vitro to form a heterosymmetric protein complex.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 12, 2021
2014 journal article
An unsupported metal hydroxide for the design of molecular μ-oxo bridged heterobimetallic complexes [Erratum to document cited in CA160:321591]
Chemical Communications, 50(67), 9608.
Source: NC State University Libraries
Added: December 24, 2020
2014 journal article
Superexchange Contributions to Distance Dependence of Electron Transfer/Transport: Exchange and Electronic Coupling in Oligo(para-Phenylene)- and Oligo(2,5-Thiophene)-Bridged Donor-Bridge-Acceptor Biradical Complexes [Erratum to document cited in CA159:719548]
Journal of American Chemical Society, 136(10), 4089.
Sources: Web Of Science, NC State University Libraries
Added: December 24, 2020
2014 journal article
Screening Analysis of Heroin Samples for Possible Cutting Agents and Adulterants
ToxTalk, 38(3), 12–16. https://www.soft-tox.org/files/toxtalk/SOFT_ToxTalk_v38-3.pdf
Source: NC State University Libraries
Added: November 16, 2020
2014 journal article
SketchBio: a scientist’s 3D interface for molecular modeling and animation
BMC Bioinformatics, 15(1).
author keywords: Molecular modelling; Animation; Collision detection
MeSH headings : Computer Simulation; Humans; Models, Molecular; Molecular Conformation; Software
TL;DR:
SketchBio is presented, a tool that incorporates state-of-the-art bimanual interaction and drop shadows to enable rapid construction of molecular structures and animations and includes three novel features: crystal-by-example, pose-mode physics, and spring-based layout that accelerate operations common in the formation of molecular models.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 4, 2020
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
