Works Published in 2023
Displaying works 1 - 20 of 40 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2023 journal article
mTOR-dependent loss of PON1 secretion and antiphospholipid autoantibody production underlie autoimmunity-mediated cirrhosis in transaldolase deficiency
Journal of Autoimmunity.
TL;DR:
Glycosylation and secretion of PON1 and aPL production are identified as mTOR-dependent regulatory checkpoints of autoimmunity underlying liver cirrhosis in TAL deficiency.
(via Semantic Scholar)
Source: ORCID
Added: February 1, 2024
2023 journal article
Publisher Correction: Cytosolic aldose metabolism contributes to progression from cirrhosis to hepatocarcinogenesis
Nature Metabolism.
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: February 1, 2024
2023 journal article
Cytosolic aldose metabolism contributes to progression from cirrhosis to hepatocarcinogenesis
Nature Metabolism.
TL;DR:
It is shown that mitochondrial oxidative stress and progression from cirrhosis to HCC and acetaminophen-induced liver necrosis are critically dependent on NADPH depletion and polyol buildup by aldose reductase (AR), while this enzyme protects from carbon trapping in the PPP and growth restriction in TAL deficiency.
(via Semantic Scholar)
Source: ORCID
Added: February 1, 2024
2023 journal article
Excision of a Protein-Derived Amine for <i>p</i>-Aminobenzoate Assembly by the Self-Sacrificial Heterobimetallic Protein CADD
BIOCHEMISTRY, 62(22), 3276–3282.
TL;DR:
Turnover studies using limiting O2 have identified a para-aminobenzaldehyde metabolic intermediate that is formed on the path to pABA formation and use of pABCHO and other probe substrates shows that the heterobimetallic Fe/Mn form of the enzyme is capable of oxygen insertion to generate the pA BA-carboxylate.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 29, 2024
2023 journal article
Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing
Biotechnology and Bioengineering.
Contributors: T. Williams , Y. Oh, K. Mendola, L. Choe, L. Min, A. Lavoie, K. Lee, Y. Yigzaw
Ed(s): T. Williams
Source: ORCID
Added: January 28, 2024
2023 journal article
Achieving Cross-Ring Fragmentation of <i>N</i>-Linked Glycans by IR-MALDESI
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 35(1), 166–171.
author keywords: N-linked glycans; lithium doping; fragmentation; IR-MALDESI; cross-ring fragment
Sources: Web Of Science, ORCID
Added: January 16, 2024
2023 journal article
Identification and biosynthesis of plant papanridins, a group of novel oligomeric flavonoids
MOLECULAR PLANT, 16(11), 1773–1793.
author keywords: flavanol polymerase; papanridin; flavan-3-ol; flav-2-en-3-ol; flavan-; flaven
TL;DR:
A new polymerization pathway of a group of novel oligomeric flavonoids in plants is reported, termed 'papanridins', which will drive further investigations across plant science, nutrition, and animal sciences, seeking to unravel the significance of papanridin in both plants and food products.
(via Semantic Scholar)
Source: Web Of Science
Added: December 18, 2023
2023 article
Discovery of a Hybrid System for Photocatalytic CO<sub>2</sub> Reduction via Attachment of a Molecular Cobalt-Quaterpyridine Complex to a Crystalline Carbon Nitride
McGuigan, S., Tereniak, S. J., Donley, C. L., Smith, A., Jeon, S., Zhao, F., … Maggard, P. A. (2023, October 12). ACS APPLIED ENERGY MATERIALS, Vol. 10.
author keywords: hybrid materials; photocatalysis; carbon nitride; CO2 reduction
Sources: Web Of Science, NC State University Libraries
Added: November 20, 2023
2023 journal article
Synthesis, characterization, computational studies, and reactivity of platinum(II) complexes of alkyl phosphite ligands
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 999.
author keywords: Organoplatinum(II) complexes; Phosphite ligands; X-ray crystallography; Computational chemistry
Source: Web Of Science
Added: November 20, 2023
2023 article
Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing
Oh, Y. H., Mendola, K. M., Choe, L. H., Min, L., Lavoie, A. R., Sripada, S. A., … Lenhoff, A. M. (2023, October 25). BIOTECHNOLOGY AND BIOENGINEERING, Vol. 10.
author keywords: bioprocessing; Chinese hamster ovary cells; host-cell proteins; monoclonal antibodies; purification
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 6, 2023
2023 journal article
Using Multidimensional Separations to Distinguish Isomeric Amino Acid-Bile Acid Conjugates and Assess Their Presence and Perturbations in Model Systems
ANALYTICAL CHEMISTRY, 95(41), 15357–15366.
TL;DR:
This work analyzed 8 core bile acids synthetically conjugated with 22 proteinogenic and nonproteogenic amino acids totaling 176 MCBAs and created an in-house extended bile acid library that was applied to healthy mice dosed with antibiotics and humans having fecal microbiota transplantation (FMT) to assess the MCBA presence and changes in the gut before and after each perturbation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: October 30, 2023
2023 journal article
Evaluating the optimal tissue thickness for mass spectrometry imaging using infrared matrix-assisted laser desorption electrospray ionization
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 37(22).
TL;DR:
This work defines an optimal sample thickness for IR-MALDESI-MSI and demonstrates the utility of optimizing tissue thickness for MSI platforms of comparable Z resolution.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 30, 2023
2023 journal article
Pseudo-affinity capture of <i>K. phaffii</i> host cell proteins in flow-through mode: Purification of protein therapeutics and proteomic study
SEPARATION AND PURIFICATION TECHNOLOGY, 326.
Contributors: S. Sripada n, D. Elhanafi*, L. Collins n , T. Williams n , M. Linova*, J. Woodley *, C. Boi, S. Menegatti n
author keywords: Komagataella phaffii; Chromatography; Protein purification; Monoclonal antibodies; Antibody fragment; Proteomics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 23, 2023
2023 journal article
Multiplex CRISPR editing of wood for sustainable fiber production
SCIENCE, 381(6654), 216-+.
TL;DR:
This work demonstrates that genome editing can be harnessed for breeding more efficient trees, which will provide timely opportunities for sustainable forestry and a more efficient bioeconomy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: October 16, 2023
2023 article
Comparative analysis of sucrose-embedding for whole-body zebrafish MSI by IR-MALDESI
Wang, M. F., Ritter, M. M., Kullman, S. W., & Muddiman, D. C. (2023, August 29). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 8.
author keywords: IR-MALDESI; Mass spectrometry imaging; Sucrose; PFA; Zebrafish
TL;DR:
Danio rerio, or zebrafish, are model organisms for various disease states and can be imaged as a multi-organ sample to analyze morphological and metabolomic preservation as a result of sample preparation to compare sucrose-embedding with paraformaldehyde fixation against conventional fresh-frozen sample preparation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: September 25, 2023
2023 journal article
A Ferric-Superoxide Intermediate Initiates P450-Catalyzed Cyclic Dipeptide Dimerization
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.
Source: Web Of Science
Added: September 11, 2023
2023 article
Metabolite Annotation Confidence Score (MACS): A Novel MSI Identification Scoring Tool
Eisenberg, S. M., Knizner, K. T., & Muddiman, D. C. (2023, August 22). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 8.
author keywords: IR-MALDESI; annotation scoring; mass measurementaccuracy; spectral accuracy; SSIM; MATLAB
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: September 5, 2023
2023 article
Maximized Spatial Information and Minimized Acquisition Time of Top-Hat IR-MALDESI-MSI of Zebrafish Using Nested Regions of Interest (nROIs)
Joignant, A. N., Ritter, M. M., Knizner, K. T., Garrard, K. P., Kullman, S. W., & Muddiman, D. C. (2023, August 1). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 8.
author keywords: IR-MALDESI; mass spectrometry imaging; spatialresolution; nested region of interest; zebrafish
TL;DR:
The nROI method was characterized on mouse liver and applied to top-hat MSI of zebrafish using a novel optical train, which resulted in a significant improvement in both acquisition time and spatial detail of the zebra fish.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 21, 2023
2023 journal article
Characterization of protein concentrates obtained by defatting cricket, locust, and silkworm powders using one-step organic solvent extraction
LWT-FOOD SCIENCE AND TECHNOLOGY, 182.
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 21, 2023
2023 journal article
Enhanced Detection of Charged N-Glycans in the Brain by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometric Imaging
ANALYTICAL CHEMISTRY, 95(29), 10913–10920.
TL;DR:
This work demonstrates the first application of IR-MALDESI in N-linked glycan imaging of the brain tissue, leading to a 2.5-fold increase in the in situ total brain N-glycan detection compared to the current gold standard of positive-mode matrix-assisted laser desorption/ionization mass spectrometry imaging.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 31, 2023
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