Works Published in 2020
Displaying works 101 - 120 of 304 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
Environmental stressors affect intestinal permeability and repair responses in a pig intestinal ischemia model
TISSUE BARRIERS, 8(4).
author keywords: Intestinal barrier; ischemia; stress; pig model; tight junctions
MeSH headings : Animals; Disease Models, Animal; Humans; Intestines / physiopathology; Ischemia / physiopathology; Permeability; Swine
TL;DR:
The effects of a period of environmental acclimation versus acute transport stress on mucosal barrier repair after intestinal ischemic injury and recovery are reported.
(via Semantic Scholar)
www.tandfonline.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 27, 2020
2020 journal article
Molecular Assessment of Chelonid Alphaherpesvirus 5 Infection in Tumor-Free Green (Chelonia mydas) and Loggerhead (Caretta caretta) Sea Turtles in North Carolina, USA, 2015–2019
Animals.
author keywords: antibodies; ChHV5; ELISA; qPCR; rehabilitation; subclinical infection
TL;DR:
This finding suggests that loggerheads infected with ChHV5 at some point in their life may be more able than green turtles to mount an effective immune response against recrudescent infection, pointing to species-specific genetic differences in the two species’ immune response to ChhV5 infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Source: ORCID
Added: October 27, 2020
2020 review
Current Approaches to the Management of Acute Thoracolumbar Disc Extrusion in Dogs
[Review of ]. FRONTIERS IN VETERINARY SCIENCE, 7.
author keywords: dog; interveterbral disc; intervertebral disc disease; hemilaminectomy; spinal cord injury; hansen type I
TL;DR:
There is no evidence to support treatment of the 48 h time point as a cut off beyond which it becomes impossible for dogs to achieve locomotor recovery, and recommendations for standard care can be made in some areas, particularly with respect to surgical decompression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: October 26, 2020
2020 journal article
Ehrlichia chaffeensis EplA Interaction With Host Cell Protein Disulfide Isomerase Promotes Infection
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 10.
author keywords: Ehrlichia; protein disulfide isomerase; Intracellular bacteria; bacterial invasion; adhesin; anaplamataceae
MeSH headings : Adhesins, Bacterial; Animals; Dogs; Ehrlichia chaffeensis; Ehrlichiosis; Monocytes; Protein Disulfide-Isomerases
TL;DR:
EplA contributes to E. chaffeensis infection of monocytic cells by engaging PDI and exploiting the enzyme's reduction of host cell surface disulfide bonds in an EplA C-terminus-dependent manner and is identified as a novel ehrlichial receptor binding domains.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: October 26, 2020
2020 journal article
Enhanced biodiversity of gut flora and feed efficiency in pond cultured tilapia under reduced frequency feeding strategies
PLOS ONE, 15(7).
MeSH headings : Animal Feed; Animals; Aquaculture; Biodiversity; Gastrointestinal Microbiome; Gene Expression Regulation; Membrane Transport Proteins / genetics; Nutrients / metabolism; Tilapia / genetics; Tilapia / growth & development; Tilapia / microbiology
TL;DR:
These studies indicate feeding Nile tilapia on alternate days along with weekly pond fertilization has no deleterious effects on growth, survivability, or production versus daily feeding regimes, but enhances feed efficiency by 76% and provides the greatest net return on investments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: October 26, 2020
2020 journal article
Perinatal androgens organize sex differences in mast cells and attenuate anaphylaxis severity into adulthood
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(38), 23751–23761.
author keywords: mast cell; sex differences; immune; inflammation; histamine
MeSH headings : Anaphylaxis; Androgens / pharmacology; Animals; Disease Models, Animal; Female; Inflammation; Male; Mast Cells / drug effects; Mast Cells / physiology; Mice; Mice, Transgenic; Sex Factors; Testis / cytology; Testis / drug effects
TL;DR:
It is shown that perinatal, but not adult gonadal, androgens play a protective role in MC-mediated anaphylaxis severity into adulthood, and proposed thatPerinatal androgens mediate their protective effects via programming of bone marrow MC precursors to exhibit reduced granule histamine and release.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: October 26, 2020
2020 journal article
Retrospective evaluation of the safety and tolerability of pimobendan in cats with obstructive vs nonobstructive cardiomyopathy
JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(6), 2211–2222.
author keywords: cardiac; cardiomyopathy; feline; hypertrophic; positive inotrope
MeSH headings : Animals; Cardiomyopathies / drug therapy; Cardiomyopathies / veterinary; Cardiotonic Agents / adverse effects; Cat Diseases / drug therapy; Cats; Heart Failure / drug therapy; Heart Failure / veterinary; Pyridazines / adverse effects; Retrospective Studies
TL;DR:
Pimobendan is well tolerated in cats with cardiomyopathy and CHF, regardless of the presence of OTO, and was discontinued due to adverse effects in 4/260 cats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 26, 2020
2020 journal article
Pathologic Lesions of the Budgett Frog (Lepidobatrachus laevis), an Emerging Laboratory Animal Model
COMPARATIVE MEDICINE, 70(3), 239–247.
MeSH headings : Animal Experimentation; Animals; Anura; Developmental Biology; Female; Male; Models, Animal; Retrospective Studies
TL;DR:
This retrospective analysis is the first description of histologic lesions identified in captive L. laevis populations, providing new insight into spontaneous disease processes occurring in this species for use in disease diagnosis and clinical management.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, ORCID
Added: October 26, 2020
2020 chapter
Tumors of the Endocrine System
In D. M. Vail, D. H. Thamm, & J. M. Liptak (Eds.), Withrow and MacEwen's Small Animal Clinical Oncology (6th edition, pp. 565–596).
Ed(s): D. Vail, D. Thamm & J. Liptak
Sources: Crossref, NC State University Libraries
Added: October 23, 2020
2020 journal article
Sustained treatment of retinal vascular diseases with self-aggregating sunitinib microparticles
Nature Communications, 11(1), 694.
MeSH headings : Animals; Choroidal Neovascularization / drug therapy; Choroidal Neovascularization / genetics; Choroidal Neovascularization / metabolism; Female; Humans; Male; Mice; Mice, Inbred C57BL; Rabbits; Receptors, Vascular Endothelial Growth Factor / antagonists & inhibitors; Receptors, Vascular Endothelial Growth Factor / genetics; Receptors, Vascular Endothelial Growth Factor / metabolism; Retinal Diseases / drug therapy; Retinal Diseases / genetics; Retinal Diseases / metabolism; Sunitinib / administration & dosage; Sunitinib / chemistry; Sunitinib / pharmacokinetics; Swine; Swine, Miniature; Vascular Endothelial Growth Factor A / genetics; Vascular Endothelial Growth Factor A / metabolism
TL;DR:
A microparticle-loaded tyrosine kinase inhibitor therapy is developed, which is effective for six months after a single injection in preclinical models, and provides a promising approach to achieve sustained suppression of VEGF signaling and improve outcomes in patients with retinal vascular diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, ORCID, Crossref
Added: October 20, 2020
2020 chapter
Ocular diseases of the Order Perissodactyla: Wild horses, Zebras, Tapirs, Rhinoceros
In K. N. Gelatt (Ed.), Veterinary Ophthalmology (6th edition). Hoboken, NJ: Wiley-Blackwell.
Ed(s): K. Gelatt
Source: NC State University Libraries
Added: October 20, 2020
2020 journal article
Lyophilized platelets versus cryopreserved platelets for management of bleeding in thrombocytopenic dogs: A multicenter randomized clinical trial
JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(6), 2384–2397.
author keywords: canine; hemorrhage; immune thrombocytopenia; transfusion; trehalose
MeSH headings : Animals; Blood Platelets; Dog Diseases / therapy; Dogs; Hemorrhage / therapy; Hemorrhage / veterinary; Platelet Count / veterinary; Platelet Transfusion / veterinary; Thrombocytopenia / therapy; Thrombocytopenia / veterinary
TL;DR:
A novel trehalose‐stabilized canine LP product appears to be logistically superior and is clinically non‐inferior to DMSO‐st stabilized canine CPP for management of bleeding in thrombocytopenic dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 19, 2020
2020 article
Modelling marine diseases
MARINE DISEASE ECOLOGY, pp. 233–255.
TL;DR:
Examining epidemiological models that consider transmission processes and parasite life histories unique to marine systems, and then incorporates disease processes in fisheries assessment models, concludes by overviewing ocean circulation models and their use in understanding parasite dispersal and spread in marine ecosystems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 19, 2020
2020 review
Ambulation in Dogs With Absent Pain Perception After Acute Thoracolumbar Spinal Cord Injury
[Review of ]. FRONTIERS IN VETERINARY SCIENCE, 7.
author keywords: spinal walking; deep pain negative; intervertebral disc herniation; canine; locomotion; gait generation
TL;DR:
Improved understanding of the mechanisms of gait generation and plasticity of the surviving tissue after injury might pave the way for further treatment options and enhanced outcomes in severely injured dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: October 19, 2020
2020 journal article
Echocardiographic reference intervals with allometric scaling of 823 clinically healthy rhesus macaques (Macaca mulatta)
BMC VETERINARY RESEARCH, 16(1).
author keywords: Heart; Cardiac; Cardiovascular; Ultrasound; Non-human primate; Cardiomyopathy; Hypertrophic cardiomyopathy; Left ventricular hypertrophy
MeSH headings : Age Factors; Animals; Body Weight; Echocardiography / veterinary; Female; Heart Rate; Hypnotics and Sedatives / administration & dosage; Ketamine / administration & dosage; Macaca mulatta / physiology; Male; Reference Values
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 19, 2020
2020 chapter
Surgical disorders of the large intestine
In B. P. Smith, D. C. Van Metre, & N. Pusterla (Eds.), Large Animal Internal Medicine (6th edition). St. Louis, MO: Elsevier.
Ed(s): B. Smith, D. Van Metre & N. Pusterla
Source: NC State University Libraries
Added: October 18, 2020
2020 chapter
Surgical disorders of the small intestine
In B. P. Smith, D. C. Van Metre, & N. Pusterla (Eds.), Large Animal Internal Medicine (6th edition). St. Louis: Elsevier.
Ed(s): B. Smith, D. Van Metre & N. Pusterla
Source: NC State University Libraries
Added: October 18, 2020
2020 content posted
Gold Nanoparticles Induce Cell Stress by Interfering with the Cellular Protein Quality Control System
TL;DR:
This study for the first time shows that NPs can interfere with the cellular PQC system by impairing ERAD activity, which in turn initiates a cascade of events leading to cell death and inflammation.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: October 16, 2020
2020 article
Revisiting the use of hydroxyethyl starch solutions in equine fluid therapy
EQUINE VETERINARY EDUCATION.
author keywords: horse; hydroxyethyl starch; colloid osmotic pressure; oncotic pressure; colloid
TL;DR:
The information presented here serves to review the physiology of oncotic pressure and the rationale behind colloid use, specifically HES solutions and the foundation of arguments against the use of HES are summarized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: October 14, 2020
2020 article
Whole-genome sequencing identifies missense mutation inGRM6as the likely cause of congenital stationary night blindness in a Tennessee Walking Horse
EQUINE VETERINARY JOURNAL.
author keywords: horse; congenital stationary night blindness (CSNB); genetics; genomics; Tennessee Walking Horse; GRM6
MeSH headings : Animals; Eye Diseases, Hereditary / genetics; Eye Diseases, Hereditary / veterinary; Genetic Diseases, X-Linked; Horse Diseases / genetics; Horses; Mutation, Missense; Myopia; Night Blindness / genetics; Night Blindness / veterinary; Receptors, Glutamate / genetics; Tennessee
TL;DR:
A likely causal recessive missense variant in metabotropic glutamate receptor 6 (GRM6) is identified, which alters GRM6 binding, and thus signaling from the retinal rod cell to the ON-bipolar cell, impairing vision in low light conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: October 14, 2020
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