Works Published in 1995

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Displaying works 121 - 127 of 127 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

1995 journal article

Piroxicam: Evidence for local delivery following topical application

European Journal of Pharmaceutics and Biopharmaceutics, 41, 175–183.

By: M. Francoeur, N. Monteiro-Riviere & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

Isolated perfused porcine skin flap as an in vitro model for predicting transdermal pharmacokinetics

European Journal of Pharmaceutics and Biopharmaceutics, 41, 152–162.

By: J. Riviere, N. Monteiro-Riviere & P. Williams

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

INDIRECT IMMUNOHISTOCHEMISTRY AND IMMUNOELECTRON MICROSCOPY DISTRIBUTION OF 8 EPIDERMAL-DERMAL JUNCTION EPITOPES IN THE PIG AND IN ISOLATED-PERFUSED SKIN TREATED WITH BIS (2-CHLOROETHYL) SULFIDE

TOXICOLOGIC PATHOLOGY, 23(3), 313–325.

Contributors: N. Monteiroriviere n & A. Inman n

author keywords: PIG SKIN; IPPSF; DERMATOTOXICOLOGY; SULFUR MUSTARD; MORPHOLOGY; EPIDERMAL DERMAL JUNCTION; LAMININ; TYPE IV COLLAGEN; FIBRONECTIN; GB3; BULLOUS PEMPHIGOID; EPIDERMOLYSIS BULLOSA ACQUISITA; L3D; 19-DEJ-1
MeSH headings : Animals; Antibodies, Monoclonal / immunology; Basement Membrane / chemistry; Basement Membrane / drug effects; Basement Membrane / ultrastructure; Collagen / analysis; Epidermolysis Bullosa Acquisita / immunology; Epitopes / analysis; Female; Fibronectins / analysis; Immunohistochemistry; In Vitro Techniques; Laminin / analysis; Microscopy, Immunoelectron; Mustard Gas / toxicity; Skin / chemistry; Skin / drug effects; Skin / ultrastructure; Swine; Trihexosylceramides / analysis
TL;DR: P pig skin and the IPPSF may be used to study HD-induced vesication and blistering diseases and the conservation of human epitopes in the EDJ of the pig further emphasizes the similarities between human skin and pig skin. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

1995 journal article

EVALUATION OF PROTECTIVE EFFECTS OF SODIUM THIOSULFATE, CYSTEINE, NIACINAMIDE AND INDOMETHACIN ON SULFUR MUSTARD-TREATED ISOLATED-PERFUSED PORCINE SKIN

CHEMICO-BIOLOGICAL INTERACTIONS, 96(3), 249–262.

author keywords: SULFUR MUSTARD; SODIUM THIOSULFATE; CYSTEINE; NIACINAMIDE; INDOMETHACIN; ISOLATED PERFUSED SKIN; TOXICOLOGY
MeSH headings : Animals; Cysteine / pharmacology; Dinoprostone / metabolism; Female; Indomethacin / pharmacology; Mustard Gas / toxicity; Niacinamide / pharmacology; Skin / blood supply; Skin Diseases / chemically induced; Skin Diseases / pathology; Swine; Thiosulfates / pharmacology
TL;DR: Data suggest that none of these agents alone would be successful antivesicant agents and different mechanisms are involved in production of HD-induced dark basal cells, microvesicles and the vascular response; unfortunately, blocking of the cellular toxicity as evidenced by dark basal cell formation did not prevent vesication, suggesting that other mechanisms must be operative and that there is a multistep, biochemical process that leads to a final lesion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

1995 journal article

ENHANCING OR BLOCKING EFFECT OF FENVALERATE ON THE SUBSEQUENT PERCUTANEOUS-ABSORPTION OF PESTICIDES IN-VITRO

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 51(3), 214–219.

TL;DR: The total absorption of these pesticides, both ethanol control and fenvalerate or parathion pretreated, increased proportionally with the dose; however, the absorption efficiency (fraction of applied dose absorbed) decreased as the dose increased. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1995 journal article

DETECTION OF SULFUR MUSTARD BIS(2-CHLOROETHYL) SULFIDE AND METABOLITES AFTER TOPICAL APPLICATION IN THE ISOLATED-PERFUSED PORCINE SKIN FLAP

LIFE SCIENCES, 56(17), 1385–1394.

author keywords: PIG SKIN; IPPSF; SULFUR MUSTARD; THIODIGLYCOL
TL;DR: Experiments showed that little, if any, HD appears in the venous perfusate intact after percutaneous absorption and that epidermal metabolism of HD does occur to a significant degree in the IPPSF. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

1995 journal article

ASSESSMENT OF SULFUR MUSTARD INTERACTION WITH BASEMENT-MEMBRANE COMPONENTS

CELL BIOLOGY AND TOXICOLOGY, 11(2), 89–101.

author keywords: ADHESION; ALKYLATION; BASEMENT MEMBRANE; KERATINOCYTE; SULFUR MUSTARD; VESICATION
MeSH headings : Alkylating Agents / toxicity; Basement Membrane / drug effects; Basement Membrane / metabolism; Blister / chemically induced; Cell Adhesion / drug effects; Cells, Cultured; Cross-Linking Reagents / toxicity; Cysteine / pharmacology; Dermatologic Agents / antagonists & inhibitors; Dermatologic Agents / toxicity; Fibronectins / chemistry; Fibronectins / drug effects; Fibronectins / metabolism; Heparan Sulfate Proteoglycans; Heparitin Sulfate / chemistry; Heparitin Sulfate / metabolism; Heparitin Sulfate / physiology; Humans; Keratinocytes / drug effects; Keratinocytes / metabolism; Laminin / chemistry; Laminin / drug effects; Laminin / metabolism; Mustard Gas / toxicity; Proteoglycans / chemistry; Proteoglycans / metabolism; Proteoglycans / physiology; Thiosulfates / pharmacology
TL;DR: The hypothesis that the alkylation of basement membrane components by HD destabilizes the epidermal-dermal junction in the process of HD-induced vesication is supported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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