Works Published in 2019

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2019 journal article

NMDA Receptor-Dependent Cholinergic Modulation of Mesolimbic Dopamine Cell Bodies: Neurochemical and Behavioral Studies


By: M. Spanos n, X. Xie n, J. Gras-Najjar n, S. White n & L. Sombers n

author keywords: Glutamate; acetylcholine; dopamine; sensory stimuli; ventral tegmental area
MeSH headings : Animals; Cell Body / drug effects; Cell Body / metabolism; Cholinergic Agonists / administration & dosage; Dopamine / metabolism; Male; Microinjections / methods; N-Methylaspartate / administration & dosage; Photic Stimulation / methods; Psychomotor Performance / drug effects; Psychomotor Performance / physiology; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate / agonists; Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors; Receptors, N-Methyl-D-Aspartate / metabolism; Ventral Tegmental Area / drug effects; Ventral Tegmental Area / metabolism
TL;DR: It is suggested that acetylcholine and glutamate synergistically act at dopamine cells in the VTA to modulate VTA-NAc shell dopaminergic output, and this underlies motivation to lever press for a motivationally neutral visual stimulus. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 9, 2019

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