Center for Environmental and Health Effects of PFAS

Recent Works

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Sorted by most recent date added to the index first, which may not be the same as publication date order.

2025 journal article

Comparative proteomic analysis of skin wound healing responses to biomaterial treatments identifies key pathways which govern differential regenerative outcomes

BIOMATERIALS, 326.

author keywords: Proteomics; Gene ontology; MAP scaffold; Chirality; Regeneration; Wound healing
topics (OpenAlex): Wound Healing and Treatments; Tendon Structure and Treatment; Periodontal Regeneration and Treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: September 29, 2025

2025 journal article

Techno-economics of hydrocarbon fuel production and recyclables recovery from landfill-destined municipal solid waste: AI-enhanced materials recovery facility design

Journal of Cleaner Production.

By: R. Thiyagarajan, R. Rao, M. Salas, N. Haque, A. Sarker, R. Kumar, A. Tripathy, V. Srinivasan ...

author keywords: Municipal solid waste; Intermediate chemicals and sugars; Sustainable aviation fuels; Artificial intelligence; Techno-economic analysis; Sustainability
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 16, 2025

2025 journal article

Per‐ and polyfluoroalkyl substances in agricultural systems: Human dietary exposure via beef raised on corn stover from a field with contaminated biosolids

Journal of Environmental Quality.

By: A. Bhattacharya, J. Tian, S. Choyke, J. Brown, P. Meng, G. Rhodes, A. Patterson, D. Knappe ...

topics (OpenAlex):
Source: ORCID
Added: September 9, 2025

2025 journal article

Embryonic Exposure to TPhP Elicits Osteotoxicity via Metabolic Disruption in <i>Oryzias latipes</i>

TOXICS, 13(8).

By: M. Gronske n, J. Cochran n, J. Foland n, D. Jima n, D. Buchwalter n, H. Stapleton*, S. Kullman n

author keywords: triphenyl phosphate; medaka; metabolic disruption; skeletal toxicity
topics (OpenAlex): Toxic Organic Pollutants Impact; Environmental Toxicology and Ecotoxicology; Effects and risks of endocrine disrupting chemicals
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 8, 2025

2025 article

Detection and Quantitation of Per- and Polyfluoroalkyl Substances in North Carolina Sea Foam and the Corresponding Sea Water

Enders, J. R., Weed, R. A., Donovan, E., Phelps, D., Campbell, G., May, K., & Baker, E. S. (2025, August 27). ENVIRONMENTAL SCIENCE & TECHNOLOGY, Vol. 8.

By: J. Enders, R. Weed, E. Donovan, D. Phelps, G. Campbell, K. May, E. Baker

author keywords: PFAS contamination; sea foam accumulation; high-resolution mass spectrometry (HRMS); quantitative analysis; nontargeted analysis; per- and polyfluoroalkyl substances(PFAS); emerging PFAS compounds
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 27, 2025

2025 article

Mechanistic Insights into Visible-Light-Induced ATRA Reactions Powered by the Symbiotic Relationship between Cu(II)/Cu(I) Phenanthroline Complexes

Arteta, S., Deegbey, M., Durand, N., Kibbe, R., Floss, J., Barth, A. T., … Castellano, F. N. (2025, August 26). ACS CATALYSIS, Vol. 8.

author keywords: photochemistry; photocatalysts; charge transfer; copper phenanthrolines; ATRA reactions
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 26, 2025

2025 article

Temperature Programming Secondary Electrospray Ionization (TP-SESI): A Novel Approach for Mass Spectrometry Analysis of Plant Volatile Organic Compounds

Ashbacher, S. M., & Muddiman, D. C. (2025, July 30). ANALYTICAL CHEMISTRY, Vol. 7.

By: S. Ashbacher n & D. Muddiman n

topics (OpenAlex): Mass Spectrometry Techniques and Applications; Analytical Chemistry and Chromatography; Advanced Chemical Sensor Technologies
Sources: Web Of Science, NC State University Libraries
Added: August 11, 2025

2025 journal article

Two-stage estimators for spatial confounding with point-referenced data

BIOMETRICS, 81(3).

By: N. Wiecha n, J. Hoppin n & B. Reich n

author keywords: bias reduction; double machine learning; Gaussian process; semiparametric regression
MeSH headings : Computer Simulation; Humans; Models, Statistical; Spatial Regression; Confounding Factors, Epidemiologic; Bias; Machine Learning; Biometry / methods; Data Interpretation, Statistical; Normal Distribution
topics (OpenAlex): Economic and Environmental Valuation; Spatial and Panel Data Analysis; Health Systems, Economic Evaluations, Quality of Life
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 24, 2025

2025 journal article

Variability of Mercury Concentrations Across Species, Brand, and Tissue Type in Processed Commercial Seafood Products

TOXICS, 13(6).

By: K. Rock n, S. Bhoothapuri n, E. Lassiter n, L. Segedie & S. Belcher n

author keywords: mercury; seafood; canned food; fish; tuna
topics (OpenAlex): Mercury impact and mitigation studies; Meat and Animal Product Quality; Toxic Organic Pollutants Impact
Sources: Web Of Science, NC State University Libraries
Added: June 30, 2025

2025 journal article

Conditional knockout of C/EBPβ in epidermis results in dysregulated lipid biosynthesis and a defect in skin barrier function

PLOS ONE, 20(6).

By: K. Mills n, M. Doyle n, J. House n, J. Witherspoon n, D. Krakko n, W. Stutts n, J. Chappel n, J. Hall n, E. Baker n, R. Smart n

Ed(s): S. Raza

MeSH headings : Animals; Epidermis / metabolism; Mice; Mice, Knockout; Lipid Metabolism / genetics; Lipids / biosynthesis; CCAAT-Enhancer-Binding Proteins / genetics; CCAAT-Enhancer-Binding Proteins / metabolism; Keratinocytes / metabolism; Lipogenesis / genetics; Lipidomics
topics (OpenAlex): melanin and skin pigmentation; Retinoids in leukemia and cellular processes; Plant Molecular Biology Research
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 25, 2025

2025 journal article

Short-chain per- and polyfluoroalkyl substances associate with elevated alanine aminotransferase: Cross-sectional analysis results from the STRIVE cohort

ENVIRONMENTAL RESEARCH, 283.

By: B. Seo*, H. Wang*, R. Maguire n, Y. Liu n, B. Smith n, K. Haller*, M. Riggan*, D. V. Conti* ...

author keywords: [MeSH]; Fluorocarbons; Liver cirrhosis; Liver diseases; Alanine transaminase
topics (OpenAlex): Per- and polyfluoroalkyl substances research; Atmospheric chemistry and aerosols; Carbon Dioxide Capture Technologies
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 17, 2025

2025 journal article

Mitochondrial Preparation from Microglia for Glycan Analysis

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 5(219).

By: M. Madabhushi, T. Palomino*, M. Patil, D. Muddiman*, D. Tyrrell & J. Samal

MeSH headings : Microglia / chemistry; Microglia / metabolism; Polysaccharides / analysis; Mitochondria / chemistry; Mitochondria / metabolism; Animals; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Mitochondrial Proteins / chemistry; Mitochondrial Proteins / analysis; Mitochondrial Proteins / isolation & purification; Mitochondrial Proteins / metabolism; Mice
topics (OpenAlex): Neuroinflammation and Neurodegeneration Mechanisms; Glycosylation and Glycoproteins Research; Neurological Disease Mechanisms and Treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 16, 2025

2025 journal article

Pressure Sensor Placement in Water Distribution Systems Using Leak Resolution-Specific Surrogates for Leak Localization

JOURNAL OF WATER RESOURCES PLANNING AND MANAGEMENT, 151(7).

By: L. Basnet n, D. Brill n, R. Ranjithan n & K. Mahinthakumar n

topics (OpenAlex): Water Systems and Optimization; Water Quality Monitoring Technologies; Intravenous Infusion Technology and Safety
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 27, 2025

2025 journal article

Profiling the Tox21 Compound Library for Their Inhibitory Effects on Cytochrome P450 Enzymes

International Journal of Molecular Sciences.

MeSH headings : Cytochrome P-450 Enzyme Inhibitors / pharmacology; Cytochrome P-450 Enzyme Inhibitors / chemistry; Humans; Cytochrome P-450 Enzyme System / metabolism; Cytochrome P-450 Enzyme System / chemistry; Small Molecule Libraries / pharmacology; Small Molecule Libraries / chemistry
topics (OpenAlex): Pharmacogenetics and Drug Metabolism; Cancer Treatment and Pharmacology; Computational Drug Discovery Methods
Source: ORCID
Added: May 22, 2025

2025 article

Unraveling the molecular dynamics of wound healing: integrating spatially resolved lipidomics and temporally resolved proteomics

Bai, H., Arnedo, A. S., Liu, Y., Segura, T., & Muddiman, D. (2025, April 24). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 4.

By: H. Bai n, A. Arnedo*, Y. Liu*, T. Segura* & D. Muddiman n

author keywords: Wound healing; Mass spectrometry imaging; 3D; IR-MALDESI; Multi-omics
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Forensic Entomology and Diptera Studies; Spectroscopy Techniques in Biomedical and Chemical Research
Sources: Web Of Science, NC State University Libraries
Added: May 6, 2025

2025 journal article

Feasibility of IR-MALDESI Mass Spectrometry Imaging of PFAS

JOURNAL OF MASS SPECTROMETRY, 60(2).

author keywords: IR-MALDESI; LC-MS/MS; mass spectrometry imaging; PFAS; zebrafish
MeSH headings : Fluorocarbons / analysis; Animals; Mice; Limit of Detection; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Liver / chemistry; Liver / metabolism; Alkanesulfonic Acids / analysis; Caprylates / analysis; Feasibility Studies; Environmental Pollutants / analysis; Tandem Mass Spectrometry / methods; Zebrafish / metabolism
topics (OpenAlex): Per- and polyfluoroalkyl substances research; Lanthanide and Transition Metal Complexes; Mass Spectrometry Techniques and Applications
Sources: Web Of Science, NC State University Libraries
Added: April 28, 2025

2025 article

Distinguishing the Metabolic Effect of Fetal and Adult Fibrinogen on Human Fibroblast Cell Culture by IR-MALDESI Mass Spectrometry Imaging

Joignant, A. N., Sheridan, A., Brown, A. C., & Muddiman, D. C. (2025, April 7). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 4.

author keywords: IR-MALDESI; mass spectrometry imaging; fibroblast; fibrinogen
topics (OpenAlex): Blood properties and coagulation; Erythrocyte Function and Pathophysiology; Adipokines, Inflammation, and Metabolic Diseases
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 21, 2025

2025 article

Trophic Transfer of Perfluoroalkyl Acids in a Periphyton-Mayfly-Zebrafish Food Chain

Farrell, M. R., Buchwalter, D. B., Weed, R. A., Enders, J. R., & Planchart, A. J. (2025, April 15).

By: M. Farrell, D. Buchwalter*, R. Weed, J. Enders* & A. Planchart

topics (OpenAlex): Per- and polyfluoroalkyl substances research
Source: ORCID
Added: April 15, 2025

2025 journal article

Per- and Polyfluoroalkyl Ether Acid (PFEA) Concentrations in Indoor Dust are Higher in Homes Closer to a Fluorochemical Manufacturing Facility

Environmental Science & Technology.

By: S. Proctor n, J. Hoppin n, S. Zhang*, H. Stapleton*, D. Knappe n & N. Kotlarz n

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
MeSH headings : Dust / analysis; Air Pollution, Indoor / analysis; Fluorocarbons / analysis; Humans; Housing; Environmental Monitoring; North Carolina; Chemical Industry
topics (OpenAlex): Per- and polyfluoroalkyl substances research; Air Quality and Health Impacts; Atmospheric chemistry and aerosols
Source: ORCID
Added: March 31, 2025

2025 article

Topographic imaging with automatic z-axis correction of <i>Brassica oleracea</i> var. <i>viridis</i> leaves by IR-MALDESI mass spectrometry imaging

Mills, Q., Ashbacher, S. M., Sohn, A. L., & Muddiman, D. C. (2025, March 15). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 3.

By: Q. Mills n, S. Ashbacher n, A. Sohn n & D. Muddiman n

author keywords: IR-MALDESI; Mass spectrometry imaging; Plant imaging; Plant metabolomics; Plant biology; <italic>Brassica oleracea</italic> var. <italic>viridis</italic>
MeSH headings : Brassica / chemistry; Plant Leaves / chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Spectrometry, Mass, Electrospray Ionization / methods
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Metabolomics and Mass Spectrometry Studies; Analytical Chemistry and Chromatography
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 19, 2025

2025 article

Glycosaminoglycan Mass Spectrometry Imaging by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

Palomino, T. V., & Muddiman, D. C. (2025, March 4). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 3.

By: T. Palomino n & D. Muddiman n

author keywords: Chondroitin Sulfate; Glycosaminoglycans; MassSpectrometry Imaging; IR-MALDESI
MeSH headings : Animals; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Chondroitin Sulfates / analysis; Chondroitin Sulfates / chemistry; Spectrometry, Mass, Electrospray Ionization / methods; Brain Chemistry; Glycosaminoglycans / analysis; Glycosaminoglycans / chemistry; Rats; Disaccharides / analysis; Disaccharides / chemistry; Male; Mice; Brain / diagnostic imaging; Brain / metabolism
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Proteoglycans and glycosaminoglycans research; Analytical Chemistry and Chromatography
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: March 17, 2025

2025 journal article

Integrating AI-powered text mining from PubTator into the manual curation workflow at the Comparative Toxicogenomics Database

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION, 2025.

MeSH headings : Toxicogenetics; Data Mining / methods; Data Curation / methods; Humans; Databases, Factual; Workflow; Databases, Genetic
topics (OpenAlex): Biomedical Text Mining and Ontologies; Genetics, Bioinformatics, and Biomedical Research; Bioinformatics and Genomic Networks
Sources: Web Of Science, NC State University Libraries
Added: March 10, 2025

2025 article

Release of Per- and Polyfluoroalkyl Substances from Municipal and Construction and Demolition Waste Landfills and Wastewater Treatment Plants in North Carolina

ACS ES&T Water.

By: J. Thelusmond n, M. Sardarmehni n, N. Destefano n, R. Weed n, D. Knappe n & M. Barlaz n

author keywords: landfill leachate; domesticwastewater; municipalsolid waste; perfluoroalkyl sulfonic acids; perfluoroalkylcarboxylic acids; fluorotelomer acids; per- andpolyfluoroalkyl ether acids
topics (OpenAlex): Per- and polyfluoroalkyl substances research; Toxic Organic Pollutants Impact; Atmospheric chemistry and aerosols
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 6, 2025

2025 journal article

Part A: Implementing an Analyte Panel and Sampling Protocol for Quality Control in Mass Spectrometry Imaging

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 39(8).

By: Q. Mills n, R. Kibbe n, A. Sohn n, A. Percy*, K. Backiel* & D. Muddiman n

author keywords: IR-MALDESI; mass spectrometry imaging; quality control; stable isotope labeled; system suitability testing
topics (OpenAlex): Mass Spectrometry Techniques and Applications; Metabolomics and Mass Spectrometry Studies; Analytical Chemistry and Chromatography
Sources: Web Of Science, NC State University Libraries
Added: March 3, 2025

2025 journal article

Part B: SLICE-MSI-A Machine Learning Interface for System Suitability Testing of Mass Spectrometry Imaging Platforms

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 39(8).

By: R. Kibbe n, Q. Mills n, A. Sohn n & D. Muddiman n

author keywords: graphical user interface; machine learning; mass spectrometry imaging; quality control; system suitability testing
topics (OpenAlex): Machine Learning in Materials Science; Metabolomics and Mass Spectrometry Studies; Mass Spectrometry Techniques and Applications
Sources: Web Of Science, NC State University Libraries
Added: March 3, 2025

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