Center for Environmental and Health Effects of PFAS

Works Published in 2009

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Displaying works 21 - 40 of 91 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2009 journal article

Within-person variability in urinary phthalate metabolite concentrations: measurements from specimens after long-term frozen storage

Journal of Exposure Science & Environmental Epidemiology, 20(2), 169–175.

By: D. Baird*, T. Saldana*, P. Nepomnaschy*, J. Hoppin*, M. Longnecker*, C. Weinberg*, A. Wilcox*

author keywords: biomarker; phthalate; reproducibility; menstrual cycle; temporal variability
MeSH headings : Cryopreservation; Female; Freezing; Humans; Menstrual Cycle; Phthalic Acids / urine; Reference Standards; Reproducibility of Results
TL;DR: Results suggest that the measurement of phthalate metabolites after long-term sample storage yield generally similar distributions and temporal reliability as those reported for recently collected specimens, and support the use of stored urine specimens collected during the relevant stage of human pregnancy to investigate the influence ofphthalate exposures on later outcomes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 2, 2020

2009 journal article

Assessment of a pesticide exposure intensity algorithm in the agricultural health study

Journal of Exposure Science & Environmental Epidemiology, 20(6), 559–569.

By: K. Thomas*, M. Dosemeci*, J. Coble*, J. Hoppin*, L. Sheldon*, G. Chapa*, C. Croghan*, P. Jones* ...

author keywords: 2,4-D; chlorpyrifos; exposure measurement; occupational exposure; Agricultural Health Study
MeSH headings : 2,4-Dichlorophenoxyacetic Acid / analysis; 2,4-Dichlorophenoxyacetic Acid / urine; Agriculture; Air Pollutants, Occupational / analysis; Air Pollutants, Occupational / urine; Algorithms; Biomarkers / urine; Chlorpyrifos / analysis; Chlorpyrifos / urine; Cohort Studies; Environmental Exposure / analysis; Environmental Monitoring / methods; Gas Chromatography-Mass Spectrometry; Humans; Iowa; Linear Models; North Carolina; Occupational Exposure / analysis; Pesticides / analysis; Pesticides / urine; Risk Assessment / methods; Skin Absorption; Surveys and Questionnaires
TL;DR: The results of the measurements support the use of the algorithm for estimating questionnaire-based exposure intensities in the AHS for liquid pesticide products and refine the algorithm may be possible using the results from this and other measurement studies. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 2, 2020

2009 journal article

Species-dependent hepatic metabolism of immunosuppressive agent tacrolimus (FK-506)

Xenobiotica, 39(10), 757–765.

By: P. Tata, N. Subbotina, G. Burckart, D. Muddiman*, A. Gusev, D. Hercules, T. Starzl, R. Venkataramanan

author keywords: Tacrolimus; species differences; liver microsomes; cytochrome P-450; secondary ion mass spectrometry (SIMS); matrix-assisted laser desorption ionization (MALDI)
MeSH headings : Animals; Chromatography, High Pressure Liquid; Cricetinae; Cytochrome P-450 Enzyme System / metabolism; Dogs; Guinea Pigs; Humans; Immunosuppressive Agents / chemistry; Immunosuppressive Agents / metabolism; Kinetics; Microsomes, Liver / enzymology; Papio; Rabbits; Rats; Species Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tacrolimus / chemistry; Tacrolimus / metabolism
TL;DR: From the current in-vitro metabolism studies, the pattern of tacroliums metabolism in baboons closely resembled that in humans and thus it is ideal for studying tacrolimus metabolism-related work of clinical relevance. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2009 journal article

Binding site on human immunoglobulin G for the affinity ligand HWRGWV

Journal of Molecular Recognition, n/a-n/a.

By: H. Yang n, P. Gurgel n, D. Williams n, B. Bobay n, J. Cavanagh n, D. Muddiman n, R. Carbonell n

author keywords: hexamer ligand; immunoglobulin G; glycosylation; mass spectrometry; computational docking; binding site
MeSH headings : Amino Acid Sequence; Animals; Binding Sites; Endopeptidases / metabolism; Humans; Immunoglobulin Fc Fragments / metabolism; Immunoglobulin G / chemistry; Immunoglobulin G / metabolism; Ligands; Models, Molecular; Molecular Sequence Data; Nerve Tissue Proteins / metabolism; Oligopeptides / chemistry; Oligopeptides / genetics; Oligopeptides / metabolism; Pepsin A / metabolism; Protein Binding; Protein Structure, Tertiary; Sequence Alignment; Staphylococcal Protein A / metabolism
TL;DR: The results support the fact that a peptide as small as a hexamer can have specific interactions with large proteins such as hIgG and the HWRGWV ligand. (via Semantic Scholar)
Source: Crossref
Added: February 24, 2020

2009 conference paper

Characterizing Reactive Contaminant Sources in a Water Distribution System

World Environmental and Water Resources Congress 2009. Presented at the World Environmental and Water Resources Congress 2009.

By: J. Kumar n, E. Brill n, G. Mahinthakumar n & R. Ranjithan n

Event: World Environmental and Water Resources Congress 2009

UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2009 conference paper

A Hybrid Heuristic Search Approach for Contaminant Source Characterization

World Environmental and Water Resources Congress 2009. Presented at the World Environmental and Water Resources Congress 2009.

By: L. Liu n, E. Brill n, G. Mahinthakumar n & S. Ranjithan n

Event: World Environmental and Water Resources Congress 2009

TL;DR: An investigation that builds upon the prior work by introducing a hybrid heuristic search method for the real-time characterization of a contaminant source by integrating the ES-based ADOPT with a logistic regression analysis and a local improvement method to expedite the convergence and possibly solve the problem quickly. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2009 journal article

DNA Hairpin, Pseudoknot, and Cruciform Stability in a Solvent-Free Environment

Journal of Physical Chemistry B, 113(6), 1722–1727.

By: E. Baker*, N. Dupuis* & M. Bowers*

Contributors: E. Baker*, N. Dupuis* & M. Bowers*

MeSH headings : Computer Simulation; DNA / chemistry; Models, Chemical; Nucleic Acid Conformation; Solvents; Spectrometry, Mass, Electrospray Ionization
TL;DR: To determine the stability of these structures, DNA sequences capable of forming each were analyzed with mass spectrometry, ion mobility, and molecular dynamics calculations and indicated that stoichiometries compatible with hairpin, pseudoknot, and cruciform structures were present. (via Semantic Scholar)
Source: ORCID
Added: December 5, 2019

2009 journal article

Biases in Ion Transmission Through an Electrospray Ionization-Mass Spectrometry Capillary Inlet

Journal of the American Society For Mass Spectrometry, 20(12), 2265–2272.

MeSH headings : Artifacts; Electrophoresis, Capillary / instrumentation; Electrophoresis, Capillary / methods; Equipment Design; Equipment Failure Analysis; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization / instrumentation; Spectrometry, Mass, Electrospray Ionization / methods
Source: ORCID
Added: December 5, 2019

2009 journal article

Aminoglycoside antibiotics: A-site specific binding to 16S

International Journal of Mass Spectrometry, 283(1-3), 105–111.

By: E. Baker*, N. Dupuis* & M. Bowers*

Contributors: E. Baker*, N. Dupuis* & M. Bowers*

author keywords: Ion mobility; 16S; Mass spectrometry
TL;DR: ESI-MS, ion mobility and molecular dynamics methods were utilized in this study to analyze the A-site of 16S27 before and after the addition of ribostamycin, paromomycin and lividomycin, and found 16S 27 in a hairpin conformation while (16S27)2 existed as a cruciform. (via Semantic Scholar)
Source: ORCID
Added: December 5, 2019

2009 journal article

Within-person variability in urinary bisphenol A concentrations: Measurements from specimens after long-term frozen storage

Environmental Research, 109(6), 734–737.

By: P. Nepomnaschy*, D. Baird*, C. Weinberg*, J. Hoppin*, M. Longnecker* & A. Wilcox*

Contributors: P. Nepomnaschy*, D. Baird*, C. Weinberg*, J. Hoppin*, M. Longnecker* & A. Wilcox*

author keywords: Bisphenol A; Temporal variability; Reproducibility; Menstrual cycle
MeSH headings : Benzhydryl Compounds; Data Interpretation, Statistical; Environmental Pollutants / urine; Female; Freezing; Humans; Menstrual Cycle / physiology; Phenols / urine; Physiological Phenomena; Premenopause / physiology; Specimen Handling / methods; Time Factors; Urinalysis / methods
TL;DR: The similar distribution to NHANES samples and correlation of BPA levels taken at 2-week intervals provide indirect evidence that BPA is relatively stable during long-term freezer storage and indicate generally stable exposures over periods of weeks. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: ORCID, Crossref
Added: September 13, 2019

2009 journal article

Meeting Report: Consensus Statement—Parkinson’s Disease and the Environment: Collaborative on Health and the Environment and Parkinson’s Action Network (CHE PAN) Conference 26–28 June 2007

Environmental Health Perspectives, 117(1), 117–121.

By: J. Bronstein*, P. Carvey*, H. Chen*, D. Cory-Slechta*, D. DiMonte*, J. Duda, P. English*, S. Goldman* ...

Contributors: J. Bronstein*, P. Carvey*, H. Chen*, D. Cory-Slechta*, D. DiMonte*, J. Duda, P. English*, S. Goldman* ...

author keywords: cholesterol; coffee; dairy products; diet; dopamine; fatty acids; metals; nonsteroidal anti-inflammatory drugs; Parkinson's disease; pesticides; polychlorinated biphenyls; smoking; statins; urate
MeSH headings : Cooperative Behavior; Environment; Environmental Pollutants / toxicity; Humans; Parkinson Disease / etiology; Research
TL;DR: A multidisciplinary group of experts gathered in Sunnyvale, California, USA, in June 2007 to assess what is known about the contribution of environmental factors to PD, and came to consensus with respect to environmental contributors to PD risk. (via Semantic Scholar)
Sources: ORCID, Crossref
Added: September 13, 2019

2009 journal article

Heterocyclic aromatic amine pesticide use and human cancer risk: Results from the U.S. Agricultural Health Study

International Journal of Cancer, 124(5), 1206–1212.

By: S. Koutros*, C. Lynch*, X. Ma*, W. Lee*, J. Hoppin*, C. Christensen*, G. Andreotti*, L. Freeman* ...

Contributors: S. Koutras, C. Lynch*, M. Xiaomei*, J. Won*, J. Hoppin*, C. Christensen*, G. Andreotti*, L. Freeman* ...

author keywords: pesticides; bladder; colon; occupational exposures
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Colonic Neoplasms / chemically induced; Female; Herbicides / adverse effects; Humans; Male; Middle Aged; Nicotinic Acids / adverse effects; Occupational Exposure / adverse effects; Risk Factors; Urinary Bladder Neoplasms / chemically induced
TL;DR: Exposure to aromatic amine pesticides may be an overlooked exposure in the etiology of bladder and colon cancer and the use of imazethapyr and other imidazolinone compounds should continue to be evaluated for potential risk to humans. (via Semantic Scholar)
Sources: ORCID, Crossref
Added: September 13, 2019

2009 journal article

Cancer Incidence among Pesticide Applicators Exposed to Permethrin in the Agricultural Health Study

Environmental Health Perspectives, 117(4), 581–586.

By: J. Rusiecki*, R. Patel*, S. Koutros*, L. Beane-Freeman*, O. Landgren*, M. Bonner*, J. Coble*, J. Lubin* ...

Contributors: J. Rusiecki*, R. Patel*, S. Koutros*, L. Beane-Freeman*, O. Landgren*, M. Bonner*, J. Coble*, J. Lubin* ...

author keywords: agriculture; cancer; multiple myeloma; occupation; permethrin; pesticide applicator; pesticides; pyrethroid
MeSH headings : Adult; Female; Humans; Incidence; Insecticides; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Permethrin
TL;DR: This study found no association with most cancers analyzed, but found elevated and statistically significant risks for multiple myeloma in the highest tertiles of both lifetime exposure-days and intensity-weighted lifetime exposure days. (via Semantic Scholar)
Sources: ORCID, Crossref
Added: September 13, 2019

2009 journal article

Occupational Exposure to Metribuzin and the Incidence of Cancer in the Agricultural Health Study

Annals of Epidemiology, 19(6), 388–395.

By: J. Delancey*, M. Alavanja*, J. Coble*, A. Blair*, J. Hoppin*, H. Austin*, L. Beane Freeman*

Contributors: J. Delancey*, M. Alavanja*, J. Coble*, A. Blair*, J. Hoppin*, H. Austin*, L. Beane Freeman*

author keywords: Pesticides; Cancer; Occupation; Metribuzin; Agricultural Health Study
MeSH headings : Adult; Aged; Agriculture; Carcinogens / toxicity; Cohort Studies; Female; Hematologic Neoplasms / epidemiology; Herbicides / toxicity; Humans; Iowa / epidemiology; Leukemia / epidemiology; Lymphoma / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / analysis; Risk Factors; Surveys and Questionnaires; Triazines / toxicity
TL;DR: A potential association between metribuzin use and certain lymphohematopoietic malignancies is suggested, however, having not been observed previously, caution should be used in interpretation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Crossref
Added: September 13, 2019

2009 journal article

Levels of metabolites of organophosphate pesticides, phthalates, and bisphenol A in pooled urine specimens from pregnant women participating in the Norwegian Mother and Child Cohort Study (MoBa)

International Journal of Hygiene and Environmental Health, 212(5), 481–491.

By: X. Ye*, F. Pierik*, J. Angerer*, H. Meltzer*, V. Jaddoe*, H. Tiemeier*, J. Hoppin*, M. Longnecker*

Contributors: X. Ye*, F. Pierik*, J. Angerer*, H. Meltzer*, V. Jaddoe*, H. Tiemeier*, J. Hoppin*, M. Longnecker*

author keywords: Organophosphate (OP) pesticides; Bisphenol A (BPA); Phthalates; Biological monitoring; Environmental exposure
MeSH headings : Adolescent; Adult; Benzhydryl Compounds; Cohort Studies; Environmental Exposure / analysis; Female; Humans; Middle Aged; Norway; Organophosphates / urine; Pesticides / urine; Phenols / urine; Phthalic Acids / urine; Pregnancy
TL;DR: The higher levels of metabolites in the MoBa participants may have been from intake via pesticide residues in food, consumption of canned food, especially fish/seafood (BPA), and use of personal care products (selected phthalates). (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: ORCID, Crossref
Added: September 13, 2019

2009 journal article

Pesticide Exposure and Hypertensive Disorders During Pregnancy

Environmental Health Perspectives, 117(9), 1393–1396.

By: T. Saldana*, O. Basso, D. Baird, J. Hoppin*, C. Weinberg*, A. Blair*, M. Alavanja*, D. Sandler

Contributors: T. Saldana*, O. Basso, D. Baírd, J. Hoppin*, C. Weinberg*, A. Blair*, M. Alavanja*, D. Sandler

author keywords: pesticide exposure; preeclampsia; pregnancy-induced hypertension
MeSH headings : Adolescent; Adult; Environmental Exposure; Female; Humans; Hypertension / chemically induced; Hypertension / complications; Middle Aged; Pesticides / toxicity; Pregnancy; Pregnancy Complications, Cardiovascular / chemically induced
TL;DR: Exposure to pesticides during pregnancy may increase the risk of hypertensive disorders of pregnancy, including pregnancy-induced hypertension (PIH) and preeclampsia (PE). (via Semantic Scholar)
Sources: ORCID, Crossref
Added: September 13, 2019

2009 journal article

Pesticides and Myocardial Infarction Incidence and Mortality Among Male Pesticide Applicators in the Agricultural Health Study

American Journal of Epidemiology, 170(7), 892–900.

By: K. Mills*, A. Blair*, L. Freeman, D. Sandler* & J. Hoppin*

Contributors: K. Mills*, A. Blair*, L. Freeman, D. Sandler* & J. Hoppin*

author keywords: agriculture; cardiovascular diseases; myocardial infarction; occupational exposure; pesticides
MeSH headings : Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / mortality; Follow-Up Studies; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Myocardial Infarction / chemically induced; Myocardial Infarction / epidemiology; Myocardial Infarction / mortality; North Carolina / epidemiology; Pesticides / adverse effects; Proportional Hazards Models; Risk
TL;DR: In a population with low risk for myocardial infarction, the authors observed little evidence of increased risk of myocardioinfarction mortality or nonfatal myocardia infarctions associated with the occupational use of pesticides. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref
Added: September 13, 2019

2009 journal article

Rhinitis associated with pesticide exposure among commercial pesticide applicators in the Agricultural Health Study

Occupational and Environmental Medicine, 66(11), 718–724.

By: R. Slager*, J. Poole*, T. LeVan*, D. Sandler*, M. Alavanja* & J. Hoppin*

Contributors: R. Slager*, J. Poole*, T. LeVan*, D. Sandler*, M. Alavanja* & J. Hoppin*

MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Benomyl / toxicity; Diazinon / toxicity; Epidemiologic Methods; Glycine / analogs & derivatives; Glycine / toxicity; Humans; Male; Middle Aged; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Oxygenases / toxicity; Pesticides / toxicity; Petroleum / toxicity; Quebec / epidemiology; Rhinitis / chemically induced; Rhinitis / epidemiology; Young Adult
TL;DR: Exposure to pesticides may increase the risk of rhinitis, based on both current use and exposure–response models, and both petroleum oil and diazinon showed consistent evidence of an association with rhInitis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Crossref
Added: September 13, 2019

2009 journal article

Pesticide exposure and risk of monoclonal gammopathy of undetermined significance in the Agricultural Health Study

Blood, 113(25), 6386–6391.

By: O. Landgren*, R. Kyle*, J. Hoppin*, L. Beane Freeman*, J. Cerhan*, J. Katzmann*, S. Rajkumar*, M. Alavanja*

Contributors: O. Landgren*, R. Kyle*, J. Hoppin*, L. Beane Freeman*, J. Cerhan*, J. Katzmann*, S. Rajkumar*, M. Alavanja*

MeSH headings : Adult; Age Factors; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Blood Protein Electrophoresis; Carbon Disulfide / adverse effects; Carbon Tetrachloride / adverse effects; Cohort Studies; Dieldrin / adverse effects; Electrophoresis, Agar Gel; Humans; Iowa / epidemiology; Male; Middle Aged; Nitriles / adverse effects; North Carolina / epidemiology; Occupational Exposure; Paraproteinemias / chemically induced; Paraproteinemias / epidemiology; Pesticides / adverse effects; Prevalence; Prospective Studies; Sampling Studies
TL;DR: The prevalence of MGUS among pesticide applicators was twice that in a population-based sample of men from Minnesota, adding support to the hypothesis that specific pesticides are causatively linked to myelomagenesis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Crossref
Added: September 13, 2019

2009 journal article

Pesticide use and adult-onset asthma among male farmers in the Agricultural Health Study

European Respiratory Journal, 34(6), 1296–1303.

By: J. Hoppin*, D. Umbach, S. London, P. Henneberger, G. Kullman, J. Coble, M. Alavanja, L. Beane Freeman, D. Sandler

Contributors: J. Hoppin*, D. Umbach, S. London, P. Henneberger, G. Kullman, J. Coble, M. Alavanja, L. Beane Freeman, D. Sandler

author keywords: Allergy; farming; occupational exposure; pesticides; respiratory disease
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / etiology; Agriculture; Asthma / chemically induced; Asthma / etiology; Carbon Disulfide / toxicity; Carbon Tetrachloride / toxicity; DDT / toxicity; Ethylene Dibromide / toxicity; Humans; Iowa; Male; Middle Aged; North Carolina; Occupational Exposure; Parathion / toxicity; Pesticides / toxicity; Prospective Studies; Smoking; Surveys and Questionnaires
TL;DR: Pesticide use may be an overlooked contributor to asthma risk among farmers and there was little evidence that allergy alone was driving these associations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref
Added: September 13, 2019

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