Works Published in 2021
Displaying works 21 - 40 of 74 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2021 article
Utilizing ion mobility spectrometry-mass spectrometry for the characterization and detection of persistent organic pollutants and their metabolites
Aly, N. A., Dodds, J. N., Luo, Y.-S., Grimm, F. A., Foster, M. K., Rusyn, I., & Baker, E. S. (2021, October 20). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 10.
author keywords: Ion Mobility Spectrometry; Pesticides; Pharmaceuticals; PFAS
MeSH headings : Environmental Monitoring / methods; Humans; Ion Mobility Spectrometry / methods; Mass Spectrometry / methods; Persistent Organic Pollutants / chemistry; Persistent Organic Pollutants / metabolism; Pesticides / analysis; Pesticides / metabolism; Pharmaceutical Preparations / analysis; Pharmaceutical Preparations / metabolism; Polychlorinated Biphenyls / analysis; Polychlorinated Biphenyls / metabolism
TL;DR:
This study characterized 64 compounds including parent per- and polyfluoroalkyl substances, pesticides, polychlorinated biphenyls, industrial chemicals, and pharmaceuticals and personal care products, in addition to their metabolites and/or degradants, using ion mobility spectrometry coupled with MS (IMS-MS) as a potential rapid screening technique.
(via Semantic Scholar)
www.ncbi.nlm.nih.gov (repository)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, ORCID
Added: November 1, 2021
2021 journal article
A Zebrafish Model of Metastatic Colonization Pinpoints Cellular Mechanisms of Circulating Tumor Cell Extravasation
FRONTIERS IN ONCOLOGY, 11.
author keywords: angiopellosis; circulating tumor cell cluster; tumor cell extravasation; cancer exodus hypothesis; metastasis; osteosarcoma
TL;DR:
Together, the results provide a novel experimental framework to study discrete steps in the metastatic process and identify the versican/ECM network dysregulation as a potential contributor to osteosarcoma circulating tumor cell metastasis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: October 26, 2021
2021 article
ToxPi*GIS Toolkit: Creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS
Fleming, J., Marvel, S. W., Motsinger-Reif, A. A., & Reif, D. M. (2021, October 11). (Vol. 10). Vol. 10.
TL;DR:
An actively developed suite of software for creating, viewing, sharing, and analyzing interactive ToxPi figures in ArcGIS, and a collection of Python routines for useful data manipulation and preprocessing for both novice and advanced users looking for additional customizability are proposed.
(via Semantic Scholar)
Source: ORCID
Added: October 13, 2021
2021 journal article
Life-Cycle Assessment of a Regulatory Compliant US Municipal Solid Waste Landfill
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 55(20), 13583–13592.
author keywords: landfill; life-cycle assessment; solid waste management; greenhouse gases; capital goods
MeSH headings : Methane; Refuse Disposal; Solid Waste; Waste Disposal Facilities
TL;DR:
This study develops an LCA model for a representative U.S. MSW landfill that is responsive to landfill size, regulatory thresholds for landfill gas (LFG) collection and control, practices for LFG management (i.e., passive venting, flare, combustion for energy recovery), and four alternative schedules for L FG collection well installation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: ORCID, Web Of Science
Added: October 2, 2021
2021 journal article
Single-minded 2 is required for left-right asymmetric stomach morphogenesis
DEVELOPMENT, 148(17).
author keywords: right asymmetry; Stomach; Morphogenesis; Pitx2; Sim2; Down syndrome; Frog
MeSH headings : Animals; Anura; Basic Helix-Loop-Helix Transcription Factors / genetics; Basic Helix-Loop-Helix Transcription Factors / metabolism; Body Patterning; Embryo, Nonmammalian; Endoderm / embryology; Endoderm / metabolism; Gene Expression Regulation, Developmental; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Morphogenesis; Stomach / embryology; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR:
It is demonstrated that sim2 functions downstream of LR patterning cues to regulate key cellular properties and behaviors in the left stomach epithelium that drive asymmetric curvature, and has implications for dose-dependent roles of laterality factors in non-laterality-related birth defects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: September 27, 2021
2021 journal article
Influence of natural organic matter and pH on phosphate removal by and filterable lanthanum release from lanthanum-modified bentonite
WATER RESEARCH, 202.
author keywords: Eutrophication; Lake restoration; Lanthanum release; Humic and fulvic acid; Phosphate management
MeSH headings : Bentonite; Hydrogen-Ion Concentration; Lakes; Lanthanum; Phosphates; Phosphorus
TL;DR:
The results indicate that the PO4-binding ability of LMB is decreased in the presence of NOM, and the decrease is more pronounced at pH 8.5 than at 6.5, which provides an important basis for management of P in lakes and eutrophication control that relies on LMB applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Sources: Web Of Science, ORCID
Added: September 20, 2021
2021 journal article
Holosteans contextualize the role of the teleost genome duplication in promoting the rise of evolutionary novelties in the ray-finned fish innate immune system
Immunogenetics.
author keywords: Bowfin and gar; Multigene families; Diverse immunoglobulin domain-containing proteins (DICPs); Novel immune-type receptors (NITRs); V(D)J recombination; MHC
MeSH headings : Animals; Evolution, Molecular; Exons; Fish Proteins / genetics; Gene Duplication; Genetic Linkage; Genome; Immunity, Innate / genetics; Immunogenetics; Immunoglobulin Domains; Major Histocompatibility Complex / genetics; Multigene Family; Phylogeny; Skates, Fish / genetics; Skates, Fish / immunology; Transcriptome
TL;DR:
The receptor diversity of two clustered innate immune gene families in the teleost sister lineage: Holostei and gars is described and characterized, revealing an ancient linkage of DICPs to the major histocompatibility complex (MHC) and an evolutionary origin of NITR variable-joining exons that predate the TGD by at least 50 million years.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: September 13, 2021
2021 journal article
Rapid Characterization of Human Serum Albumin Binding for Per- and Polyfluoroalkyl Substances Using Differential Scanning Fluorimetry
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 55(18), 12291–12301.
author keywords: alcohols; carboxylic acids; fluorocarbons; perfluorocarbons; protein; sulfonic acids; telomer; thermal stability; toxicokinetic
MeSH headings : Alkanesulfonic Acids; Carboxylic Acids; Fluorocarbons; Fluorometry; Humans; Serum Albumin, Human; Sulfonic Acids
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: ORCID, Web Of Science
Added: September 9, 2021
2021 article
The bowfin genome illuminates the developmental evolution of ray-finned fishes
Thompson, A. W., Hawkins, M. B., Parey, E., Wcisel, D. J., Ota, T., Kawasaki, K., … Braasch, I. (2021, August 30). NATURE GENETICS, Vol. 8.
MeSH headings : Animals; Biological Evolution; Chromatin / genetics; Evolution, Molecular; Fishes; Genome / genetics; Skates, Fish / genetics; Skates, Fish / immunology; Skates, Fish / physiology; Whole Genome Sequencing
TL;DR:
A chromosome-level genome assembly for bowfin is presented that enables gene-order analyses, settling long-debated neopterygian phylogenetic relationships and investigates the evolution of immune, scale, respiratory and fin skeletal systems and identifies hundreds of gene-regulatory loci conserved across vertebrates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID
Added: September 7, 2021
2021 journal article
In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases
COMMUNICATIONS BIOLOGY, 4(1).
MeSH headings : Animals; Cyclooxygenase 1 / genetics; Cyclooxygenase 1 / metabolism; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Embryo, Mammalian; Mass Spectrometry; Mice; Prostaglandin-Endoperoxide Synthases / metabolism; Prostaglandins / metabolism
TL;DR:
A novel mass spectrometry imaging method is applied for direct in situ tissue localization of prostaglandin D2, its precursors, and downstream synthases and reveals that the abundance of COX and prostag landins D2 synthases in cellular regions does not mirror the regional abundance of prostags.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 30, 2021
2021 article
Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances
Kirkwood, K. I., Fleming, J., Nguyen, H., Reif, D. M., Baker, E. S., & Belcher, S. M. (2021, August 26). (Vol. 8). Vol. 8.
TL;DR:
Over 70 PFAS were detected in the pine needles from this study, providing information from the last six decades related to PFAS exposure, contamination, and reduction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: August 27, 2021
2021 journal article
High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs
PLOS GENETICS, 17(8).
Ed(s): F. Vazquez
MeSH headings : Antineoplastic Agents / pharmacology; Biomarkers, Pharmacological / analysis; Cell Line, Tumor; Genome-Wide Association Study / methods; High-Throughput Screening Assays / methods; Humans; NAD(P)H Dehydrogenase (Quinone) / drug effects; NAD(P)H Dehydrogenase (Quinone) / genetics; NAD(P)H Dehydrogenase (Quinone) / metabolism
TL;DR:
The NAD(P)H quinone dehydrogenase 1 (NQO1) gene was found to be associated with the dose-response of arsenic trioxide, erlotinib, tramet inib, and a combination treatment of paclitaxel + epirubicin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science
Added: August 27, 2021
2021 article
Utilizing liquid chromatography, ion mobility spectrometry, and mass spectrometry to assess INLIGHT (TM) derivatized N-linked glycans in biological samples
Butler, K. E., Kalmar, J. G., Muddiman, D. C., & Baker, E. S. (2021, August 4). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 8.
author keywords: Glycomics; Ion mobility spectrometry; INLIGHT (TM); N-Linked glycans; LC-IMS-MS
TL;DR:
The combination of IMS and the natural (NAT) and stable-isotope label (SIL) in the INLIGHT™ strategy provided additional confidence for each glycan identification due to the mobility aligned NAT- and SIL-labeled glycans and further capabilities for isomer examinations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 16, 2021
2021 journal article
Spatially resolved metabolomic characterization of muscle invasive bladder cancer by mass spectrometry imaging
METABOLOMICS, 17(8).
author keywords: Bladder cancer; IR-MALDESI mass spectrometry imaging; Metabolomics; Lipidomics; Intratumor heterogeneity
MeSH headings : Feasibility Studies; Humans; Metabolomics / methods; Muscle, Smooth / metabolism; Muscle, Smooth / pathology; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Urinary Bladder Neoplasms / diagnostic imaging; Urinary Bladder Neoplasms / metabolism; Urinary Bladder Neoplasms / pathology
TL;DR:
Great promise is demonstrated of IR-MALDESI MSI to identify molecular changes derived from cancer and unveil tumor heterogeneity, which can potentially promote the discovery of clinically relevant biomarkers and allow for applications in precision medicine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 2, 2021
2021 article
Understanding the electrospray ionization response factors of per- and poly-fluoroalkyl substances (PFAS)
Enders, J. R., Grace M. O'Neill, Whitten, J. L., & Muddiman, D. C. (2021, July 21). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 7.
author keywords: Electrospray ionization; PFAS; logP; Surface activity
TL;DR:
A method for predicting the behavior of individual PFAS compounds, including relative retention order in chromatography, is presented which is simply based on the number of fluorine atoms in the molecule as well as the class of the compound.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 2, 2021
2021 article
A critical overview of computational approaches employed for COVID-19 drug discovery
Muratov, E. N., Amaro, R., Andrade, C. H., Brown, N., Ekins, S., Fourches, D., … Tropsha, A. (2021, July 2). CHEMICAL SOCIETY REVIEWS.
MeSH headings : Antiviral Agents / therapeutic use; COVID-19 / virology; Clinical Trials as Topic; Computer Simulation; Drug Design; Drug Discovery / methods; Drug Repositioning; Humans; Pandemics; SARS-CoV-2 / drug effects; COVID-19 Drug Treatment
TL;DR:
It is proposed that truly impactful computational tools must deliver actionable, experimentally testable hypotheses enabling the discovery of novel drugs and drug combinations, and that open science and rapid sharing of research results are critical to accelerate the development of novel, much needed therapeutics for COVID-19.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 26, 2021
2021 journal article
Investigations of beta-carotene radical cation formation in infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI)
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 35(16).
MeSH headings : Cations / analysis; Cations / chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Tandem Mass Spectrometry; beta Carotene / analysis; beta Carotene / chemistry
TL;DR:
There are several potential mechanisms for β-carotene radical cationization prior to IR-MALDESI analysis with multiphoton-ionization, thermal degradation, and/or reaction with oxygen, but changing certain aspects of sample conditions can result in significant mixed-mode ionization with competing protonation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID
Added: July 26, 2021
2021 journal article
Data Processing Workflow to Identify Structurally Related Compounds in Petroleum Substances Using Ion Mobility Spectrometry-Mass Spectrometry
ENERGY & FUELS, 35(13), 10529–10539.
TL;DR:
This work demonstrates how rapid untargeted IMS-MS analysis and the proposed data processing workflow can be used to provide confident compositional characterization of hydrocarbon-containing substances.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: July 26, 2021
2021 journal article
Multiomic Big Data Analysis Challenges: Increasing Confidence in the Interpretation of Artificial Intelligence Assessments
ANALYTICAL CHEMISTRY, 93(22), 7763–7773.
MeSH headings : Artificial Intelligence; Big Data; Data Analysis
TL;DR:
The present and future capabilities of AI techniques in multiomic studies are discussed while introducing analytical checks and balances to validate the computational conclusions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 19, 2021
2021 journal article
In situ detection of fatty acid C=C positional isomers by coupling on-tissue mCPBA epoxidation with infrared matrix-assisted laser desorption electrospray ionization mass spectrometry
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 35(13).
TL;DR:
The on-tissue mCPBA epoxidation was implemented into an ambient MS imaging workflow to offer a rapid and simple way for in situ identification and relative quantification of double bond positional isomers without the requirement for instrument modification.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: July 6, 2021
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
