Center for Environmental and Health Effects of PFAS

Works Published in 2011

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Displaying works 41 - 60 of 94 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2011 journal article

The curation paradigm and application tool used for manual curation of the scientific literature at the Comparative Toxicogenomics Database

Database, 2011(0), bar034โ€“bar034.

By: A. Davisโ€‰*, T. Wiegers*, C. Murphy* & C. Mattingly*โ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Database Management Systems; Databases, Factual; Disease; Humans; Internet; Pharmaceutical Preparations; Toxicogenetics; User-Computer Interface; Vocabulary, Controlled
Sources: Crossref, ORCID
Added: August 7, 2019

2011 journal article

DiseaseComps: a metric that discovers similar diseases based upon common toxicogenomic profiles at CTD

Bioinformation, 7(4), 154โ€“156.

By: A. Davis, M. Rosenstein, T. Wiegers & C. Mattingly*โ€‰

Sources: Crossref, ORCID
Added: August 7, 2019

2011 journal article

A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos

Development, 139(2), 437โ€“442.

By: A. Morckel n, H. Lusic n, L. Farzana n, J. Yoder nโ€‰, A. Deitersโ€‰ n & N. Nascone-Yoderโ€‰ n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Small-molecule inhibitor; Rho kinase; Photocaging; Xenopus
MeSH headings : Animals; Body Patterning / drug effects; Dioxoles / metabolism; Dioxoles / pharmacology; Embryo, Nonmammalian / metabolism; Immunohistochemistry; Indoles / metabolism; Indoles / pharmacology; Mice; NIH 3T3 Cells; Pyridines / metabolism; Pyridines / pharmacology; Ultraviolet Rays; Xenopus laevis / embryology; Xenopus laevis / metabolism; rho-Associated Kinases / antagonists & inhibitors; rho-Associated Kinases / metabolism
Sources: ORCID, Crossref
Added: May 17, 2019

2011 journal article

Using Nuclear Receptor Activity to Stratify Hepatocarcinogens

PLoS ONE, 6(2).

By: I. Shahโ€‰*, K. Houckโ€‰*, R. Judsonโ€‰*, R. Kavlock*, M. Martin*, D. Reif*โ€‰, J. Wambaughโ€‰*, D. Dix*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: I. Shahโ€‰*, K. Houckโ€‰*, R. Judsonโ€‰*, R. Kavlock*, M. Martin*, D. Reif*โ€‰, J. Wambaughโ€‰*, D. Dix*

Ed(s): S. Wรถlfl

MeSH headings : Animals; Carcinogens / classification; Carcinogens / toxicity; Carcinoma, Hepatocellular / chemically induced; Carcinoma, Hepatocellular / genetics; Carcinoma, Hepatocellular / metabolism; Cells, Cultured; Constitutive Androstane Receptor; Disease Progression; Drug Evaluation, Preclinical / methods; Gene Expression / drug effects; Gene Expression Profiling; Gene Regulatory Networks / drug effects; High-Throughput Screening Assays / methods; Humans; Liver / drug effects; Liver / metabolism; Liver / pathology; Liver Neoplasms / chemically induced; Liver Neoplasms / genetics; Liver Neoplasms / metabolism; Mice; Microarray Analysis; Rats; Receptors, Cytoplasmic and Nuclear / metabolism; Receptors, Cytoplasmic and Nuclear / physiology
Source: ORCID
Added: May 14, 2019

2011 journal article

Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data.

Toxicological Sciences, 124(1), 109โ€“127.

By: N. Sipesโ€‰*, M. Martin*, D. Reif*โ€‰, N. Kleinstreuerโ€‰*, R. Judsonโ€‰*, A. Singh*, K. Chandler*, D. Dix*, R. Kavlock*, T. Knudsenโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: N. Sipesโ€‰*, M. Martin*, D. Reif*โ€‰, N. Kleinstreuerโ€‰*, R. Judsonโ€‰*, A. Singh*, K. Chandler*, D. Dix*, R. Kavlock*, T. Knudsenโ€‰*

author keywords: developmental toxicity; ToxCast; ToxRefDB; high-throughput screening; predictive models; computational models predictive toxicology
MeSH headings : Animals; Congenital Abnormalities / etiology; Databases, Factual; Embryonic Development / drug effects; Endpoint Determination; Environmental Pollutants / classification; Environmental Pollutants / toxicity; Fetal Development / drug effects; High-Throughput Screening Assays; Models, Biological; Rabbits; Rats; Species Specificity; Teratogens / classification; Teratogens / toxicity; United States; United States Environmental Protection Agency
Source: ORCID
Added: May 14, 2019

2011 journal article

Predictive model of rat reproductive toxicity from ToxCast high throughput screening.

Biology of Reproduction, 85(2), 327โ€“339.

By: M. Martin*, T. Knudsenโ€‰*, D. Reif*โ€‰, K. Houckโ€‰*, R. Judsonโ€‰*, R. Kavlock*, D. Dix*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: M. Martin*, T. Knudsenโ€‰*, D. Reif*โ€‰, K. Houckโ€‰*, R. Judsonโ€‰*, R. Kavlock*, D. Dix*

author keywords: female reproductive tract; fertility; male reproductive tract; predictive toxicology; reproductive toxicity; toxicology
MeSH headings : Animals; Environmental Pollutants / toxicity; Gene Expression Regulation / drug effects; Male; Predictive Value of Tests; Rats; Reproduction / drug effects; Risk Assessment; Small Molecule Libraries; Toxicity Tests / methods; United States; United States Environmental Protection Agency
Source: ORCID
Added: May 14, 2019

2011 conference paper

Optimization of grammatical evolution decision trees

Proceedings of the 13th annual conference companion on Genetic and evolutionary computation - GECCO '11, 35โ€“36.

By: K. Hoover n, R. Marceau n, T. Harris n, N. Hardison n, D. Reif nโ€‰ & A. Motsinger-Reifโ€‰ n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: K. Hoover n, R. Marceau n, T. Harris n, N. Hardison n, D. Reif nโ€‰ & A. Motsinger-Reifโ€‰ n

Source: ORCID
Added: May 14, 2019

2011 journal article

Mechanistic indicators of childhood asthma (MICA) study: piloting an integrative design for evaluating environmental health.

BMC Public Health, 11, 344.

By: J. Gallagher*, E. Hudgens*, A. Williamsโ€‰*, J. Inmon*, S. Rhoney*, G. Andrews*, D. Reif*โ€‰, B. Heidenfelder* ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: J. Gallagher*, E. Hudgens*, A. Williamsโ€‰*, J. Inmon*, S. Rhoney*, G. Andrews*, D. Reif*โ€‰, B. Heidenfelder* ...

MeSH headings : Adolescent; Asthma / diagnosis; Asthma / etiology; Biomarkers / blood; Child; Disease Susceptibility; Environmental Health; Environmental Monitoring / methods; Female; Genetic Predisposition to Disease / genetics; Humans; Male; Michigan; Risk Factors
Source: ORCID
Added: May 14, 2019

2011 journal article

Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population.

BMC Medical Genetics, 12, 25.

By: B. Joubertโ€‰*, D. Reif*โ€‰, S. Edwards*, K. Leiner*, E. Hudgens*, P. Egeghyโ€‰*, J. Gallagher*, E. Hubal

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: B. Joubertโ€‰*, D. Reif*โ€‰, S. Edwards*, K. Leiner*, E. Hudgens*, P. Egeghyโ€‰*, J. Gallagher*, E. Hubal

MeSH headings : Adolescent; Black or African American / genetics; Asthma / genetics; Child; Chromosomes, Human, Pair 11 / genetics; Cross-Sectional Studies; Female; Food Hypersensitivity / genetics; Genetic Predisposition to Disease; Glutathione S-Transferase pi / genetics; Glutathione Transferase / genetics; Haplotypes; Humans; Hypersensitivity / genetics; Hypersensitivity, Immediate / genetics; Linkage Disequilibrium; Male; Michigan; Odds Ratio; Polymorphism, Single Nucleotide; Receptors, IgE / genetics; Risk Factors; Sequence Deletion; Urban Population
Source: ORCID
Added: May 14, 2019

2011 journal article

Evaluation of 309 Environmental Chemicals Using a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity Assay

PLoS ONE, 6(6), e18540.

By: K. Chandler*, M. Barrier*, S. Jeffay*, H. Nichols*, N. Kleinstreuerโ€‰*, A. Singh*, D. Reif*โ€‰, N. Sipesโ€‰* ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: K. Chandler*, M. Barrier*, S. Jeffay*, H. Nichols*, N. Kleinstreuerโ€‰*, A. Singh*, D. Reif*โ€‰, N. Sipesโ€‰* ...

Ed(s): A. Cooney

MeSH headings : Animals; Biological Assay; Cell Adhesion / drug effects; Cell Death / drug effects; Cell Differentiation / drug effects; Cell Line; Embryonic Stem Cells / cytology; Embryonic Stem Cells / drug effects; Endpoint Determination; Environmental Pollutants / toxicity; Male; Mice; Models, Biological; Multivariate Analysis; Toxicity Tests / methods
Source: ORCID
Added: May 14, 2019

2011 journal article

Environmental Impact on Vascular Development Predicted by High-Throughput Screening

Environ Health Perspect, 119(11), 1596รขย€ย“1603.

By: N. Kleinstreuerโ€‰*, R. Judsonโ€‰*, D. Reif*โ€‰, N. Sipesโ€‰*, A. Singh*, K. Chandler*, R. DeWoskin*, D. Dix*, R. Kavlock*, T. Knudsenโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: N. Kleinstreuerโ€‰*, R. Judsonโ€‰*, D. Reif*โ€‰, N. Sipesโ€‰*, A. Singh*, K. Chandler*, R. DeWoskin*, D. Dix*, R. Kavlock*, T. Knudsenโ€‰*

author keywords: angiogenesis; developmental toxicity; high-throughput screening (HTS); thalidomide; vascular development
MeSH headings : Animals; Cardiovascular System / drug effects; Cardiovascular System / embryology; Computational Biology; Databases, Factual; Environmental Pollutants / analysis; Environmental Pollutants / classification; Environmental Pollutants / immunology; Environmental Pollutants / toxicity; Female; High-Throughput Screening Assays; Humans; Male; Maternal Exposure; Mice; Models, Animal; Multivariate Analysis; Pregnancy; Rabbits; Rats; Risk Assessment; Small Molecule Libraries / analysis; Small Molecule Libraries / classification; Small Molecule Libraries / toxicity; Species Specificity; Toxicology / methods; United States; United States Environmental Protection Agency
Source: ORCID
Added: May 14, 2019

2011 journal article

Activity profiles of 309 ToxCastโ„ข chemicals evaluated across 292 biochemical targets

Toxicology, 282(1-2), 1รขย€ย“15.

By: T. Knudsenโ€‰*, K. Houckโ€‰*, N. Sipesโ€‰*, A. Singh*, R. Judsonโ€‰*, M. Martin*, A. Weissman*, N. Kleinstreuerโ€‰* ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: T. Knudsenโ€‰*, K. Houckโ€‰*, N. Sipesโ€‰*, A. Singh*, R. Judsonโ€‰*, M. Martin*, A. Weissman*, N. Kleinstreuerโ€‰* ...

author keywords: High-throughput screening; Computational toxicology; ToxCast; Environmental chemicals
MeSH headings : Animal Use Alternatives; Animals; Automation, Laboratory; Cell-Free System; Data Interpretation, Statistical; Databases, Factual; Environmental Pollutants / classification; Environmental Pollutants / toxicity; Enzyme Inhibitors / toxicity; High-Throughput Screening Assays; Humans; Ligands; Models, Biological; Osmolar Concentration; Pesticide Residues / toxicity; Rats; Reproducibility of Results; Toxicity Tests; United States; United States Environmental Protection Agency
Source: ORCID
Added: May 14, 2019

2011 journal article

Food rationing affects dietary selenium bioaccumulation and life cycle performance in the mayfly Centroptilum triangulifer

ECOTOXICOLOGY, 20(8), 1840โ€“1851.

By: J. Conley n, D. Funk*, N. Cariello* & D. Buchwalter n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Selenium; Mayfly; Periphyton; Toxicity; Maternal transfer; Fecundity; Trophic transfer; Chronic; Bioconcentration
MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Body Weight; Female; Fertility; Food Chain; Insecta / growth & development; Insecta / metabolism; Insecta / physiology; Life Cycle Stages; Ovum; Selenium / pharmacokinetics
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Membrane protein complexes catalyze both 4-and 3-hydroxylation of cinnamic acid derivatives in monolignol biosynthesis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(52), 21253โ€“21258.

By: H. Chen*, Q. Li*, C. Shuford n, J. Liu, D. Muddiman nโ€‰, R. Sederoff*, V. Chiang*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Carboxylic Ester Hydrolases / chemistry; Carboxylic Ester Hydrolases / metabolism; Chromatography, Liquid; Coumaric Acids; DNA Primers / genetics; Hydroxylation; Immunoprecipitation; Kinetics; Lignin / biosynthesis; Mass Spectrometry; Membrane Proteins / chemistry; Membrane Proteins / metabolism; Microscopy, Confocal; Molecular Structure; Multiprotein Complexes / chemistry; Multiprotein Complexes / metabolism; Phenols; Phenylpropionates; Plasmids / genetics; Populus / metabolism; Propionates; Trans-Cinnamate 4-Monooxygenase / chemistry; Trans-Cinnamate 4-Monooxygenase / metabolism; Xylem / metabolism; Yeasts
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Global optimization of the infrared matrix-assisted laser desorption electrospray ionization (IR MALDESI) source for mass spectrometry using statistical design of experiments

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 25(23), 3527โ€“3536.

By: J. Barry n & D. Muddiman nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Cattle; Cytochromes c / analysis; Cytochromes c / chemistry; Horses; Limit of Detection; Research Design; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Subsurface characterization using a D-optimality based pilot point method

JOURNAL OF HYDROINFORMATICS, 13(4), 775โ€“793.

By: Y. Jungโ€‰*, R. Ranjithan n & G. Mahinthakumar n

co-author countries: Korea (Republic of) ๐Ÿ‡ฐ๐Ÿ‡ท United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: characterization; groundwater inverse modeling; hydraulic conductivity; pilot point method
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Evaluation of Normalization Methods on GeLC-MS/MS Label-Free Spectral Counting Data to Correct for Variation during Proteomic Workflows

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 22(12), 2199โ€“2208.

By: E. Gokce n, C. Shuford n, W. Franck n, R. Dean nโ€‰ & D. Muddiman nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Label-free; Proteomics; Mass spectrometry; Total spectral count normalization; Normalized spectral abundance factor; Quantification; Spectral counting; Significance test; Fold-change; GeLC-MS/MS; nanoLC-MS; Orbitrap XL
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Cadmium exposure route affects antioxidant responses in the mayfly Centroptilum triangulifer

AQUATIC TOXICOLOGY, 105(3-4), 199โ€“205.

By: L. Xie n & D. Buchwalter n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Cadmium; Exposure route; Antioxidant enzymes; Glutathione; Periphyton; Mayfly
MeSH headings : Animals; Antioxidants / metabolism; Cadmium / analysis; Cadmium / toxicity; Catalase / metabolism; Dose-Response Relationship, Drug; Environmental Exposure / adverse effects; Food Contamination; Glutathione Transferase / metabolism; Insecta / chemistry; Insecta / drug effects; Insecta / enzymology; Larva / chemistry; Larva / drug effects; Larva / enzymology; Random Allocation; Superoxide Dismutase / metabolism; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / toxicity
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Spectral Accuracy and Sulfur Counting Capabilities of the LTQ-FT-ICR and the LTQ-Orbitrap XL for Small Molecule Analysis

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 22(12), 2269โ€“2275.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Electrospray ionization; FT-ICR-MS; Orbitrap-MS; Forensic analysis; Textiles; Trace evidence
MeSH headings : Chi-Square Distribution; Coloring Agents / chemistry; Forensic Sciences; Fourier Analysis; Mass Spectrometry / methods; Polyesters / chemistry; Sensitivity and Specificity; Sulfur / analysis; Textiles / analysis
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

One-year plasma N-linked glycome intra-individual and inter-individual variability in the chicken model of spontaneous ovarian adenocarcinoma

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 305(2-3), 79โ€“86.

By: R. Dixon n, M. Bereman n, J. Petitte nโ€‰, A. Hawkridge n & D. Muddiman nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: N-linked glycans; HILIC; FTMS; Longitudinal sampling
Sources: Web Of Science, ORCID
Added: August 6, 2018

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