Center for Environmental and Health Effects of PFAS

Works Published in 2011

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Displaying works 61 - 80 of 94 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2011 journal article

Wood Biodegradation in Laboratory-Scale Landfills

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 45(16), 6864–6871.

By: X. Wang n, J. Padgett n, F. Cruz n & M. Barlaz n

TL;DR: Wood species have unique methane yields that should be considered in the development of national inventories of methane production and carbon storage and the current assumption of uniform biodegradability is not appropriate. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

What Is the Most Environmentally Beneficial Way to Treat Commercial Food Waste?

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 45(17), 7438–7444.

MeSH headings : Agriculture / methods; Air Pollutants / analysis; Bioreactors; Carbon Dioxide / analysis; Environment; Food; Global Warming; Humans; Methane / analysis; Models, Theoretical; Nitric Oxide / chemistry; Refuse Disposal / instrumentation; Refuse Disposal / methods; Soil / chemistry; Sulfur Dioxide / chemistry; Waste Management / methods
TL;DR: A traditional landfill with energy recovery was predicted to have lower emissions than any of the composting alternatives when a fertilizer offset was used, and the use of compost to offset peat has greater emission offsets than the value of compost as a fertilizer. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Two Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Paralogs are Required for Normal Development in Zebrafish

The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 294(9), 1511–1524.

By: L. Ott n, Z. Mcdowell n, P. Turner n, J. Law n, K. Adler n, J. Yoder n, S. Jones n

author keywords: MARCKS; zebrafish; development
MeSH headings : Amino Acid Sequence; Animals; Embryo, Nonmammalian / cytology; Embryo, Nonmammalian / metabolism; Intracellular Signaling Peptides and Proteins / antagonists & inhibitors; Intracellular Signaling Peptides and Proteins / genetics; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / antagonists & inhibitors; Membrane Proteins / genetics; Membrane Proteins / metabolism; Molecular Sequence Data; Morpholinos / pharmacology; Multigene Family; Myristoylated Alanine-Rich C Kinase Substrate; Phenotype; Phylogeny; Sequence Homology, Amino Acid; Zebrafish / genetics; Zebrafish / growth & development
TL;DR: It is demonstrated that Marcksa and Marcksb are required for normal zebrafish development and suggested that zebra fish are a suitable model to further study MARCKS function. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Transformation kinetics of biochemically active compounds in low-pressure UV Photolysis and UV/H2O2 advanced oxidation processes

WATER RESEARCH, 45(15), 4531–4543.

By: C. Baeza* & D. Knappe n

Contributors: C. Baeza* & D. Knappe n

author keywords: Antibiotics; Endocrine disrupting chemicals; Pharmaceuticals; Photooxidation; Quantum yield
MeSH headings : Diclofenac / chemistry; Hydrogen Peroxide / chemistry; Hydrogen-Ion Concentration; Hydroxyl Radical / chemistry; Kinetics; North Carolina; Oxidation-Reduction; Photolysis; Trimethoprim / chemistry; Ultraviolet Rays; Water Pollutants, Chemical / chemistry; Water Purification / methods; Water Supply / standards
TL;DR: Quantum yields and second order rate constants describing the reaction between the hydroxyl radical and BACs were determined and used together with background water quality data to predict fluence-based BAC transformation rate constants (k'). (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Stable-Isotope Labeled Hydrophobic Hydrazide Reagents for the Relative Quantification of N-Linked Glycans by Electrospray Ionization Mass Spectrometry

ANALYTICAL CHEMISTRY, 83(17), 6738–6745.

MeSH headings : Carbon Isotopes / chemistry; Glycopeptides / analysis; Glycosylation; Hydrazones / chemistry; Hydrophobic and Hydrophilic Interactions; Isotope Labeling; Polysaccharides / analysis; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR: It is shown that these reagents are capable of quantifying changes in glycosylation in simple mixtures, and the analytical variability of the reagents in pooled plasma samples is shown to be less than ±30%. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Logistic regression analysis to estimate contaminant sources in water distribution systems

JOURNAL OF HYDROINFORMATICS, 13(3), 545–557.

By: L. Liu*, A. Sankarasubramanian n & S. Ranjithan n

author keywords: contaminant source; logistic regression analysis; probabilistic characterization; water distribution systems
TL;DR: A rapid estimation methodology based on logistic regression (LR) analysis to estimate the likelihood of any given node as a potential source of contamination and can also serve as a prescreening step for simulation‐optimization methods by reducing the decision space and thus alleviating the computational burden. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Comparison of stable-isotope labeling with amino acids in cell culture and spectral counting for relative quantification of protein expression

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 25(17), 2524–2532.

MeSH headings : Amino Acid Sequence; Amino Acids / chemistry; Amino Acids / metabolism; Animals; Cell Differentiation; Cell Line; Ectoderm; Embryonic Stem Cells / cytology; Embryonic Stem Cells / metabolism; Humans; Isotope Labeling / methods; Mass Spectrometry; Mice; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Proteins / analysis; Proteins / chemistry; Proteins / metabolism; Proteomics / methods; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors
TL;DR: The comparison of stable-isotope labeling of amino acids in cell culture (SILAC) with spectral counting for the quantification of human embryonic stem cells as they differentiate toward the trophectoderm at three time points is presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

CD34 antigen: Determination of specific sites of phosphorylation in vitro and in vivo

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 301(1-3), 12–21.

By: L. Deterding*, J. Williams*, M. Humble*, R. Petrovich*, S. Wei*, C. Trempus*, M. Gates*, F. Zhu n ...

author keywords: CD34; Phosphorylation; PKC kinase; AKT2 kinase; LC/MS/MS
TL;DR: The identification of the in vitro sites of phosphorylation on the intracellular domain of mouse CD34 following PKC treatment suggests that other kinases, as well as PKC, may have important signaling functions in CD34. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Increasing proteome coverage with offline RP HPLC coupled to online RP nanoLC-MS

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 879(9-10), 610–614.

By: E. Gokce n, G. Andrews n, R. Dean n & D. Muddiman n

author keywords: RP HPLC; Fractionation methods; Proteomics; Mass spectrometry
MeSH headings : Chromatography, High Pressure Liquid / methods; Chromatography, Reverse-Phase / methods; Mass Spectrometry / methods; Nanotechnology; Peptide Fragments / analysis; Peptide Fragments / metabolism; Proteome / analysis; Proteome / metabolism; Proteomics / methods; Saccharomyces cerevisiae Proteins / analysis; Saccharomyces cerevisiae Proteins / metabolism
TL;DR: The success of performing offline reversed phase high pressure liquid chromatography (HPLC) fractionation on a C18 2.0 mm×150 mm column at the peptide level with microliter per minute flow rates prior to online nano-flow reversed phase liquid Chromatography mass spectrometry (nanoLC-MS) using the well-studied fungus Saccharomyces cerevisiae is reported. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Improving Proteome Coverage on a LTQ-Orbitrap Using Design of Experiments

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 22(4), 773–783.

By: G. Andrews n, R. Dean n, A. Hawkridge n & D. Muddiman n

author keywords: LTQ-Orbitrap XL MS/MS instrument parameters; Design of experiments; Fractional-factorial design; Saccharomyces cerevisiae; Proteomics
MeSH headings : Peptide Fragments; Peptide Mapping; Proteome / chemistry; Proteomics / methods; Research Design; Saccharomyces cerevisiae Proteins / chemistry; Tandem Mass Spectrometry / methods; Temperature
TL;DR: The DOE approach represents a time- and cost-effective method for empirically optimizing MS-based proteomics workflows including sample preparation, LC conditions, and multiple instrument platforms. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Identification of alternative splice variants in Aspergillus flavus through comparison of multiple tandem MS search algorithms

BMC Genomics, 12.

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Hydrophobic Derivatization of N-linked Glycans for Increased Ion Abundance in Electrospray Ionization Mass Spectrometry

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 22(8), 1309–1317.

By: S. Walker n, L. Lilley*, M. Enamorado n, D. Comins n & D. Muddiman n

author keywords: Hydrophobic Derivatization; HILIC; nanoESI; N-Linked Glycans; Hydrazone Formation
MeSH headings : Blood Proteins / chemistry; Carbohydrate Sequence; Chromatography, Liquid; Glycoproteins / chemistry; Humans; Hydrazines / chemistry; Hydrophobic and Hydrophilic Interactions; Polysaccharides / chemistry; Small Molecule Libraries; Spectrometry, Mass, Electrospray Ionization / methods; Tandem Mass Spectrometry
TL;DR: The results of this study will direct the future synthesis of hydrophobic reagents for glycan analysis using the correlation between hydrophobicity and theoretical non-polar surface area calculation to facilitate the development of an optimum tag for gly can derivatization. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Facile Self-Assembly of Supramolecular Hexakisferrocenyl Triangles via Coordination-Driven Self-Assembly and Their Electrochemical Behavior

ORGANOMETALLICS, 30(13), 3637–3642.

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 review

Capitalizing on the hydrophobic bias of electrospray ionization through chemical modification in mass spectrometry-based proteomics

[Review of ]. EXPERT REVIEW OF PROTEOMICS, 8(3), 317–323.

By: C. Shuford n & D. Muddiman n

author keywords: ALiPHAT; electrospray ionization; hydrophobic tagging; mass spectrometry; quantification
MeSH headings : Humans; Hydrophobic and Hydrophilic Interactions; Proteomics / methods; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR: Improvements in targeted, mass spectrometry-based proteomic strategies are achieved by taking advantage of the mechanism of ESI through the use of hydrophobic chemical derivatization. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

A performance-based system for the long-term management of municipal waste landfills

WASTE MANAGEMENT, 31(4), 649–662.

MeSH headings : Cities; Conservation of Natural Resources / economics; Conservation of Natural Resources / methods; Humans; Refuse Disposal / economics; Refuse Disposal / methods; Time Factors; Waste Products / analysis; Waste Products / classification; Waste Products / economics
TL;DR: A hypothetical case study showed that using the methodology to evaluate site-specific PCC requirements could result in increased environmental protection at comparable cost by spending available funds where they are most needed. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Quantifying the Greenhouse Gas Emission Reductions Associated with Recycling Hot Mix Asphalt

ROAD MATERIALS AND PAVEMENT DESIGN, 12(1), 57–77.

By: J. Levis, M. Barlaz*, A. Tayebali & S. Ranjithan

author keywords: Life-Cycle Assessment; Recycling; Rap; Waste Asphalt Concrete; Global Warming
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

PTEN Positively Regulates UVB-Induced DNA Damage Repair

CANCER RESEARCH, 71(15), 5287–5295.

By: M. Ming n, L. Feng n, C. Shea n, K. Soltani n, B. Zhao n, W. Han n, R. Smart n, C. Trempus n, Y. He n

MeSH headings : Animals; Carcinoma, Squamous Cell / etiology; Carcinoma, Squamous Cell / genetics; Carcinoma, Squamous Cell / pathology; Cell Line / metabolism; Cell Line / pathology; Cell Line / radiation effects; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA Damage; DNA Repair / genetics; DNA Repair / physiology; DNA-Binding Proteins / physiology; Down-Regulation; Humans; Keratinocytes / metabolism; Keratinocytes / pathology; Keratinocytes / radiation effects; Keratosis, Actinic / genetics; Keratosis, Actinic / pathology; Mice; Neoplasms, Radiation-Induced / genetics; Neoplasms, Radiation-Induced / pathology; PTEN Phosphohydrolase / antagonists & inhibitors; PTEN Phosphohydrolase / deficiency; PTEN Phosphohydrolase / genetics; PTEN Phosphohydrolase / physiology; Papilloma / etiology; Papilloma / genetics; Papilloma / pathology; Precancerous Conditions / etiology; Precancerous Conditions / genetics; Protein Kinases / physiology; Protein Serine-Threonine Kinases / physiology; Proto-Oncogene Proteins c-akt / physiology; RNA, Small Interfering / pharmacology; Skin Neoplasms / etiology; Skin Neoplasms / genetics; Skin Neoplasms / pathology; Ultraviolet Rays / adverse effects; p38 Mitogen-Activated Protein Kinases / antagonists & inhibitors
TL;DR: This work shows that attenuating PTEN in epidermal keratinocytes is a predisposing factor for UVB-induced skin carcinogenesis in mice, and defines PTEN as an essential genomic gatekeeper in the skin through its ability to positively regulate XPC-dependent GG-NER following DNA damage. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

John B. Fenn special issue recognizing the science of Professor John B. Fenn foreword

International Journal of Mass Spectrometry, 300(2-3), 72–73.

By: M. El-Shall & D. Muddiman

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Is Biodegradability a Desirable Attribute for Discarded Solid Waste? Perspectives from a National Landfill Greenhouse Gas Inventory Model

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 45(13), 5470–5476.

MeSH headings : Biodegradation, Environmental; Carbon Dioxide / analysis; Computer Simulation; Garbage; Greenhouse Effect; Methane / analysis; Models, Theoretical; Paper; Polyesters; Refuse Disposal / standards
TL;DR: A landfill life-cycle model was developed to represent the behavior of MSW components and new materials disposed in a landfill representative of the U.S. average with respect to gas collection and utilization over a range of environmental conditions and Poly(3-hydroxybutyrate-co-3-Hydroxyoctanoate) (PHBO) was selected as illustrative for an emerging biodegradable polymer. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Effect of Spatial Differences in Microbial Activity, pH, and Substrate Levels on Methanogenesis Initiation in Refuse

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 77(7), 2381–2391.

By: B. Staley n, F. Reyes n & M. Barlaz n

MeSH headings : Archaea / classification; Archaea / genetics; Archaea / growth & development; Archaea / metabolism; Bacteria / classification; Bacteria / genetics; Bacteria / growth & development; Bacteria / metabolism; Cluster Analysis; DNA, Archaeal / chemistry; DNA, Archaeal / genetics; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; Fatty Acids, Volatile / metabolism; Genes, rRNA; Hydrogen-Ion Concentration; Methane / metabolism; Molecular Sequence Data; Phylogeny; Polymorphism, Restriction Fragment Length; RNA, Archaeal / genetics; RNA, Bacterial / genetics; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Waste Products
TL;DR: This study suggests that methanogens tolerant to low pH, such as M. barkeri, are required to overcome the low-pH, high-VFA conditions present during the anaerobic acid phase of refuse decomposition. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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