Works Published in 2014
Displaying works 61 - 80 of 111 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 journal article
C/EBPα regulates CRL4Cdt2-mediated degradation of p21 in response to UVB-induced DNA damage to control the G1/S checkpoint
Cell Cycle, 13(22), 3602–3610.
author keywords: C/EBP alpha; CRL4(Cdt2); G(1)/S DNA damage checkpoint; keratinocytes; p21
MeSH headings : Animals; CCAAT-Enhancer-Binding Protein-alpha / genetics; CCAAT-Enhancer-Binding Protein-alpha / metabolism; Cell Cycle Checkpoints / genetics; Cell Cycle Checkpoints / radiation effects; Cyclin-Dependent Kinase Inhibitor p21 / metabolism; DNA Damage / genetics; DNA Damage / radiation effects; G1 Phase Cell Cycle Checkpoints / genetics; Keratinocytes / metabolism; Keratinocytes / radiation effects; Mice; Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Proteolysis; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism; Ultraviolet Rays; p21-Activated Kinases / genetics; p21-Activated Kinases / metabolism
TL;DR:
Findings reveal C/EBPα regulates G1/S cell cycle arrest in response to DNA damage via the control of CRL4Cdt2 mediated degradation of p21.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Is Helicobacter Pylori an endogenous source of diethyl phthalate in humans?
Environmental Research, 134, 402–404.
author keywords: Diethyl phthalate; Monoethyl phthalate; Helicobacter pylori; NHANES; Microbiome
MeSH headings : Adolescent; Adult; Female; Helicobacter pylori / metabolism; Humans; Male; Middle Aged; Phthalic Acids / metabolism; Young Adult
TL;DR:
Results suggest that HP may be an endogenous source of DEP in some populations, and MEP levels were higher in individuals with HP seropositivity, however the association differed by race.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Functional diversification of vitamin D receptor paralogs in teleost fish after a whole genome duplication event
Endocrinology, 155(12), 4641–4654.
MeSH headings : Animals; Calcitriol / metabolism; Evolution, Molecular; Fish Proteins / genetics; Fish Proteins / metabolism; Gene Duplication; Genome; Nuclear Receptor Coactivators / metabolism; Oryzias; Receptors, Calcitriol / genetics; Receptors, Calcitriol / metabolism; Retinoid X Receptors / metabolism; Zebrafish
TL;DR:
The results imply that functional differences between VDRα and VDRβ occurred early in teleost evolution because they are conserved between distantly related species, and suggest that the observed differences may be associated with differential protein-protein interactions between the VDR paralogs and coactivators.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2014 journal article
Accuracy of residential geocoding in the Agricultural Health Study
International Journal of Health Geographics, 13(1), 37.
author keywords: Geocoding; Positional error; Rural location; Environmental exposure assessment; Accuracy
MeSH headings : Agriculture / statistics & numerical data; Cohort Studies; Environmental Exposure / analysis; Environmental Exposure / statistics & numerical data; Female; Geographic Mapping; Health Status; Humans; Iowa / epidemiology; Male; North Carolina / epidemiology; Pesticides; Prospective Studies
TL;DR:
It is suggested that where E911 locations are available, they offer an improvement upon address-matched geocodes for rural addresses, and that exposure misclassification resulting from positional error can be minimized when known coordinates are available to test alternative data and methods.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Single-Nucleotide Polymorphism Data Support the General Unrelatedness of the Males in the Agricultural Health Study
Cancer Epidemiology Biomarkers & Prevention, 23(10), 2192–2195.
MeSH headings : Agriculture; Case-Control Studies; Cohort Studies; Consanguinity; Gene-Environment Interaction; Humans; Male; Occupational Exposure; Polymorphism, Single Nucleotide; Principal Component Analysis; Research Design
TL;DR:
This analysis rejects the hypothesis that individuals in the case–control study of prostate cancer exhibit cryptic relatedness, and these findings are important for all subsequent analyses of gene–environment interactions in the AHS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Pesticide use and incident diabetes among wives of farmers in the Agricultural Health Study
Occupational and Environmental Medicine, 71(9), 629–635.
Contributors: A. Starling *, D. Umbach *, F. Kamel*, S. Long*, D. Sandler * & J. Hoppin n
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Diabetes Mellitus / epidemiology; Diabetes Mellitus / etiology; Female; Humans; Incidence; Iowa / epidemiology; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Organophosphates / toxicity; Pesticides / toxicity; Proportional Hazards Models; Spouses; Young Adult
TL;DR:
Results are consistent with previous studies reporting an association between specific organochlorines and diabetes and add to growing evidence that certain organophosphates also may increase risk, though attenuated compared with separate models.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2014 article
Focus on Advancing High Performance Mass Spectrometry, Honoring Dr. Richard D. Smith, Recipient of the 2013 Award for a Distinguished Contribution in Mass Spectrometry
Baker, E. S., Muddiman, D. C., & Loo, J. A. (2014, December). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 25, pp. 1997–1999.
Contributors: E. Baker* , D. Muddiman n & J. Loo *
TL;DR:
This special focus issue of the Journal of the American Society for Mass spectrometry celebrates the accomplishments of Dr. Richard D. Smith, the recipient of the 2013ASMS Award for a Distinguished Contribution in Mass Spectrometry.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Fertilization of Radishes, Tomatoes, and Marigolds Using a Large-Volume Atmospheric Glow Discharge
PLASMA CHEMISTRY AND PLASMA PROCESSING, 34(6), 1271–1290.
Contributors: A. Lindsay n, B. Byrns n, W. King n, A. Andhvarapou n, J. Fields n, D. Knappe n , W. Fonteno n, S. Shannon n
author keywords: Large-volume glow; Atmospheric pressure plasma; Fertilization; Reactive nitrogen and oxygen species
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Evaluating nonpolar surface area and liquid chromatography/mass spectrometry response: an application for site occupancy measurements for enzyme intermediates in polyketide biosynthesis
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 28(23), 2511–2522.
MeSH headings : Acyltransferases / metabolism; Chromatography, Liquid / methods; Filtration; Hydrophobic and Hydrophilic Interactions; Mass Spectrometry / methods; Oligopeptides / chemistry; Oligopeptides / metabolism; Peptide Fragments / chemistry; Peptide Fragments / metabolism; Polyketides / chemistry; Polyketides / metabolism
TL;DR:
The MS signal as a function of nonpolar surface area (NPSA) is explored in order to better understand this bias in electrospray response and to determine relative LC/MS response for peptides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Establishing ion ratio thresholds based on absolute peak area for absolute protein quantification using protein cleavage isotope dilution mass spectrometry
ANALYST, 139(21), 5439–5450.
MeSH headings : Chromatography, Liquid; Isotopes / chemistry; Proteins / analysis; Tandem Mass Spectrometry / methods
TL;DR:
It is suggested that evaluation of the absolute ion abundance for any given transition is necessary in order to effectively implement RA thresholds, and these RA values should be assessed as close as possible to the time at which data is collected for quantification.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
2,4-D adsorption to biochars: Effect of preparation conditions on equilibrium adsorption capacity and comparison with commercial activated carbon literature data
WATER RESEARCH, 62, 20–28.
Contributors: J. Kearns *, L. Wellborn*, R. Summers * & D. Knappe n
author keywords: Pesticide; Herbicide; Water treatment; Charcoal; Low-cost adsorbent
TL;DR:
Economic analysis showed that high temperature chars can be a cost-effective alternative to ACs for water treatment applications and increase pyrolysis intensity by increasing temperature and duration was found to positively influence adsorption capacity yield.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Synthetic organic water contaminants in developing communities: an overlooked challenge addressed by adsorption with locally generated char
JOURNAL OF WATER SANITATION AND HYGIENE FOR DEVELOPMENT, 4(3), 422–436.
Contributors: J. Kearns *, D. Knappe n & R. Summers *
author keywords: biochar; charcoal; drinking water; herbicide; pesticide; Thailand
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Mapping Antiretroviral Drugs in Tissue by IR-MALDESI MSI Coupled to the Q Exactive and Comparison with LC-MS/MS SRM Assay
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 25(12), 2038–2047.
author keywords: IR-MALDESI; Mass spectrometry imaging; LC-MS/MS; Drug distribution
MeSH headings : Adenine / analogs & derivatives; Adenine / analysis; Adenine / chemistry; Adenine / pharmacokinetics; Anti-Retroviral Agents / analysis; Anti-Retroviral Agents / chemistry; Anti-Retroviral Agents / pharmacokinetics; Cervix Uteri / chemistry; Cervix Uteri / metabolism; Chromatography, Liquid / methods; Deoxycytidine / analogs & derivatives; Deoxycytidine / analysis; Deoxycytidine / chemistry; Deoxycytidine / pharmacokinetics; Emtricitabine; Female; Histocytochemistry; Humans; Molecular Imaging / methods; Organophosphonates / analysis; Organophosphonates / chemistry; Organophosphonates / pharmacokinetics; Pyrrolidinones / analysis; Pyrrolidinones / chemistry; Pyrrolidinones / pharmacokinetics; Raltegravir Potassium; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Tandem Mass Spectrometry / methods; Tenofovir; Tissue Distribution
TL;DR:
An agreement between the average intensities from the imaging experiment and the absolute quantities for each drug was observed and this correlation between these two techniques serves as a prerequisite to quantitative IR-MALDESI MSI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Peptidoglycan recognition protein genes and risk of Parkinson's disease
Movement Disorders, 29(9), 1171–1180.
Contributors: S. Goldman*, F. Kamel*, G. Ross*, S. Jewell*, C. Marras *, J. Hoppin n , D. Umbach *, G. Bhudhikanok*
author keywords: Parkinson's disease; peptidoglycan; PGLYRP; microbiome; gut
MeSH headings : Adult; Aged; Aged, 80 and over; Carrier Proteins / genetics; Case-Control Studies; Female; Genetic Association Studies; Genetic Predisposition to Disease / genetics; Genotype; Humans; Logistic Models; Male; Microbiota / genetics; Middle Aged; Odds Ratio; Parkinson Disease / genetics; Polymorphism, Single Nucleotide / genetics
TL;DR:
Common variants in PGLYRP genes are associated with PD risk in two independent studies and are consistent with hypotheses of a causative role for the gut microbiota and gastrointestinal immune response in PD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: August 6, 2018
2014 journal article
Orthogonal zirconium diol/C18 liquid chromatography-tandem mass spectrometry analysis of poly and perfluoroalkyl substances in landfill leachate
JOURNAL OF CHROMATOGRAPHY A, 1359, 202–211.
author keywords: Landfill leachates; LVI; LC-MS/MS; PFAS
MeSH headings : Chromatography, Liquid / instrumentation; Chromatography, Liquid / methods; Fluorocarbons / chemistry; Fluorocarbons / isolation & purification; Humans; Liquid Phase Microextraction; Molecular Structure; Tandem Mass Spectrometry / instrumentation; Tandem Mass Spectrometry / methods; Waste Disposal Facilities; Water Pollutants, Chemical / chemistry; Water Pollutants, Chemical / isolation & purification; Zirconium / chemistry
TL;DR:
The 3-perfluoropentyl propanoate (5:3 FTCA) was the most concentrated analyte in most samples and constitutes a previously unreported but significant component of landfill leachate.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Hierarchical Self-Assembly of Supramolecular Hydrophobic Metallacycles into Ordered Nanostructures
CHEMISTRY-AN ASIAN JOURNAL, 9(10), 2928–2936.
author keywords: metallacycles; noncovalent interactions; nanostructures; self-assembly; supramolecular chemistry
TL;DR:
A new series of well-defined metallacycles decorated with long alkyl chains were obtained through metal-ligand interactions, which were capable of aggregating into ordered fibroid or spherical nanostructures on the surface, mostly driven by hydrophobic interactions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
A stressful shortness of breath: molting disrupts breathing in the mayfly Cloeon dipterum
FRESHWATER SCIENCE, 33(3), 695–699.
author keywords: respirometry; temperature; thermal biology; molting; oxygen consumption; Ephemeroptera
TL;DR:
The insect molt appears to be a previously unappreciated route by which warming conditions may affect aquatic insects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
A Bayesian Network Model for Assessing Natural Estrogen Fate and Transport in a Swine Waste Lagoon
INTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT, 10(4), 511–521.
MeSH headings : Animals; Bayes Theorem; Estrogens / chemistry; Models, Theoretical; Sewage / chemistry; Swine; Waste Disposal, Fluid; Water Pollutants, Chemical / chemistry
TL;DR:
Management scenario evaluations demonstrated that the best possible management options to reduce estrogen levels in the lagoon are either to adjust the estrogen input loading from swine barn facilities or to effectively enhance estrogen bonding with suspended solids through the use of organic polymers or inorganic coagulants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Transport of Steroid Hormones, Phytoestrogens, and Estrogenic Activity across a Swine Lagoon/Sprayfield System
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 48(19), 11600–11609.
MeSH headings : Agriculture / methods; Androgens / chemistry; Androstenedione / chemistry; Animals; Diet / veterinary; Environmental Monitoring / methods; Equol / chemistry; Estrogens / chemistry; Estrone / chemistry; Feces / chemistry; Genistein / chemistry; Hormones / chemistry; Isoflavones / chemistry; Phytoestrogens / chemistry; Progesterone / chemistry; Steroids / chemistry; Swine; Urine / chemistry
TL;DR:
This investigation encompasses the most comprehensive suite of natural hormone and phytoestrogen analytes examined to date across a livestock lagoon/sprayfield and provides global insight into the fate of these analytes in this widely used waste management system.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Silver dopants for targeted and untargeted direct analysis of unsaturated lipids via infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI)
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 28(22), 2461–2470.
MeSH headings : Alkenes / chemistry; Dried Blood Spot Testing; Fats, Unsaturated / analysis; Fats, Unsaturated / chemistry; Humans; Male; Silver / chemistry; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR:
Silver cationization has been shown to enhance IR-MALDESI sensitivity and selectivity for unsaturated lipids, even when applied to complex samples, and developed tools for peak assignment and mapping of isotopic patterns will clearly benefit future mass spectrometry imaging studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
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