Center for Environmental and Health Effects of PFAS

Works Published in 2011

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Displaying works 81 - 94 of 94 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2011 journal article

Design, modeling, fabrication, and evaluation of the air amplifier for improved detection of biomolecules by electrospray ionization mass spectrometry

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 300(2-3), 99–107.

By: G. Robichaud*, R. Dixon, A. Potturi, D. Cassidy*, J. Edwards*, A. Sohn*, T. Dow*, D. Muddiman* 

author keywords: Air amplifier; Electrospray ionization; Modeling; Detection limits
TL;DR: A computer simulation that accurately portrays actual conditions and the results from these simulations are corroborated by the experimental data is developed, which can be used to predict outcomes from future designs resulting in a design process that is efficient in terms of financial cost and time. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Observations on the methane oxidation capacity of landfill soils

WASTE MANAGEMENT, 31(5), 914–925.

By: J. Chanton*, T. Abichou*, C. Langford*, K. Spokas *, G. Hater, R. Green, D. Goldsmith, M. Barlaz n 

MeSH headings : Air Pollutants / analysis; Air Pollutants / metabolism; Air Pollution / statistics & numerical data; Environmental Monitoring; Methane / analysis; Methane / metabolism; Oxidation-Reduction; Refuse Disposal / statistics & numerical data; Soil / chemistry; Soil Microbiology
TL;DR: The data indicate that an effective way to increase the % oxidation of a landfill cover is to limit the amount of CH(4) delivered to it, which should not be considered as a constant value. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Expression and function of triggering receptor expressed on myeloid cells-1 (TREM-1) on canine neutrophils

Developmental & Comparative Immunology, 35(8), 872–880.

By: J. Li, A. Birkenheuer* , H. Marr*, M. Levy*, J. Yoder*  & S. Nordone

author keywords: TREM-1; TLR; Neutrophils; Sepsis; Canine
MeSH headings : Amino Acid Sequence; Animals; Cells, Cultured; Cloning, Molecular; Conserved Sequence; Cytokines / immunology; Cytokines / metabolism; Dogs / genetics; Dogs / immunology; Humans; Lipopolysaccharides / immunology; Lipopolysaccharides / pharmacology; Membrane Glycoproteins / genetics; Membrane Glycoproteins / immunology; Membrane Glycoproteins / metabolism; Molecular Sequence Data; Neutrophils / immunology; Neutrophils / metabolism; Phylogeny; Receptors, Immunologic / genetics; Receptors, Immunologic / metabolism; Sequence Alignment; Teichoic Acids / immunology; Teichoic Acids / pharmacology; Toll-Like Receptors / agonists; Up-Regulation / drug effects
TL;DR: Functionally, canine TREM-1 synergistically enhances LPS-induced production of IL-8, TNF-α and a canine orthologue of CXCL1 and these data suggest that T REM-1 expression in dogs is an amplifier of pro-inflammatory responses to microbial products. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

C/EBP alpha Expression Is Downregulated in Human Nonmelanoma Skin Cancers and Inactivation of C/EBP alpha Confers Susceptibility to UVB-Induced Skin Squamous Cell Carcinomas

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 131(6), 1339–1346.

By: E. Thompson n, S. Zhu n, J. Hall n, J. House n , R. Ranjan n, J. Burr n, Y. He *, D. Owens *, R. Smart n 

MeSH headings : Animals; CCAAT-Enhancer-Binding Protein-alpha / analysis; CCAAT-Enhancer-Binding Protein-alpha / physiology; Carcinoma, Squamous Cell / chemistry; Carcinoma, Squamous Cell / etiology; Cell Cycle; Cells, Cultured; Genes, p53; Humans; Keratosis, Actinic / metabolism; Male; Mice; Mice, Hairless; Mice, Inbred C57BL; Mutation; Neoplasms, Radiation-Induced / etiology; Precancerous Conditions / chemistry; Skin / metabolism; Skin / radiation effects; Skin Neoplasms / chemistry; Skin Neoplasms / etiology; Ultraviolet Rays / adverse effects
TL;DR: It is observed that C/EBPα is induced in normal human epidermal keratinocytes and in the epidermis of human subjects exposed to UVB radiation, and loss of C/ EBPα confers susceptibility toUVB-induced skin SCCs involving defective cell cycle arrest in response to UVBs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Performance Characteristics of a New Hybrid Quadrupole Time-of-Flight Tandem Mass Spectrometer (TripleTOF 5600)

ANALYTICAL CHEMISTRY, 83(13), 5442–5446.

By: G. Andrews n, B. Simons, J. Young, A. Hawkridge  n & D. Muddiman n 

MeSH headings : Fungal Proteins / metabolism; Proteome; Saccharomyces cerevisiae / metabolism; Tandem Mass Spectrometry / instrumentation; Trypsin / metabolism
TL;DR: The TripleTOF 5600 System, a hybrid quadrupole time-of-flight mass spectrometer, was evaluated to explore the key figures of merit in generating peptide and protein identifications that included spectral acquisition rates, data quality, proteome coverage, and biological depth. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Characterization of natural organic matter adsorption in granular activated carbon adsorbers

WATER RESEARCH, 45(13), 3951–3959.

By: S. Velten*, D. Knappe n , J. Traber*, H. Kaiser*, U. Gunten *, M. Boller *, S. Meylan*

Contributors: S. Velten*, D. Knappe  n, J. Traber*, H. Kaiser*, U. Gunten *, M. Boller *, S. Meylan*

author keywords: Adsorption; Granular activated carbon; Natural organic matter (NOM); NOM characterization; Size exclusion chromatography
MeSH headings : Adsorption; Charcoal / chemistry; Chromatography, Gel; Organic Chemicals / chemistry; Organic Chemicals / isolation & purification; Water Pollutants, Chemical / chemistry; Water Pollutants, Chemical / isolation & purification; Water Purification / methods
TL;DR: In both GAC adsorbers, adsorbability of the remaining NOM fractions, compared on the basis of partition coefficients, increased with decreasing molecular size, suggesting that increasingly larger portions of the internal GAC surface area could be accessed as the size of NOM decreased. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 article

John Bennett Fenn (1917-2010)

Muddiman, D. C. (2011, January 14). SCIENCE, Vol. 331, pp. 160–160.

By: D. Muddiman n 

MeSH headings : Chemistry / history; History, 20th Century; History, 21st Century; Nobel Prize; Spectrometry, Mass, Electrospray Ionization / history; United States
TL;DR: The Nobel Prize in Chemistry did not define John Fenn, nor did it change him; he was the same man before and after, always showing a strong sense of humility. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species

BMC BIOCHEMISTRY, 12.

By: M. Krasowski *, N. Ai, L. Hagey*, E. Kollitz n, S. Kullman n , E. Reschly*, S. Ekins *

MeSH headings : Animals; Bile Acids and Salts / metabolism; Evolution, Molecular; Humans; Ligands; Mice; Models, Molecular; Pregnane X Receptor; Protein Interaction Domains and Motifs; Rats; Receptors, Calcitriol / genetics; Receptors, Calcitriol / metabolism; Receptors, Cytoplasmic and Nuclear / genetics; Receptors, Cytoplasmic and Nuclear / metabolism; Receptors, Steroid / genetics; Receptors, Steroid / metabolism; Species Specificity; Structure-Activity Relationship; Tetraodontiformes; Zebrafish
TL;DR: These studies provide further evidence of the relationship between both FXR, PXR, and VDR ligand selectivity and cross-species variation in bile salt profiles and suggest a ligand-binding pocket architecture more similar to human and rat FXRs than to lamprey or zebrafish FXRs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Quantitative determination of fluorochemicals in municipal landfill leachates

CHEMOSPHERE, 82(10), 1380–1386.

By: C. Huset*, M. Barlaz n , D. Barofsky * & J. Field *

author keywords: Fluorochemicals; Perfluorochemicals; Landfill leachate; PFOA; PFBA; PFOS
MeSH headings : Alkanesulfonic Acids / analysis; Caprylates / analysis; Chromatography, Liquid; Environmental Monitoring / methods; Fluorocarbons / analysis; Fluorocarbons / chemistry; Refuse Disposal; Solid Phase Extraction; Tandem Mass Spectrometry; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / chemistry; Water Pollution, Chemical / statistics & numerical data
TL;DR: Twenty-four fluorochemicals were quantified in landfill leachates recovered from municipal refuse using an analytical method based on solid-phase extraction, dispersive-carbon sorbent cleanup, and liquid chromatography/tandem mass spectrometry, finding that short-chain carboxylates or sulfonates were greater in abundance than their respective longer-chain homologs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Contamination Source Identification in Water Distribution Systems Using an Adaptive Dynamic Optimization Procedure

JOURNAL OF WATER RESOURCES PLANNING AND MANAGEMENT, 137(2), 183–192.

By: L. Liu  n, S. Ranjithan n & G. Mahinthakumar n

author keywords: Identification; Water distribution systems; Contamination; Algorithms
TL;DR: An adaptive dynamic optimization technique (ADOPT) is proposed for providing a real-time response to a contamination event and a new multiple population–based search that uses an evolutionary algorithm (EA) is investigated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 review

The phylogenetic origins of natural killer receptors and recognition: relationships, possibilities, and realities

[Review of ]. IMMUNOGENETICS, 63(3), 123–141.

By: J. Yoder n  & G. Litman*

author keywords: Marsupial; Monotreme; Chicken; Xenopus; Zebrafish; Innate immunity; Cytotoxicity
MeSH headings : Animals; Evolution, Molecular; Humans; Immunity, Innate; Killer Cells, Natural / immunology; Mammals / genetics; Mammals / immunology; Phylogeny; Receptors, Natural Killer Cell / genetics; Receptors, Natural Killer Cell / immunology; Receptors, Natural Killer Cell / metabolism; Vertebrates / genetics; Vertebrates / immunology
TL;DR: Several lines of evidence suggest that NK-type function or its equivalent has sustained a long evolutionary history throughout vertebrate species and likely reflects the influence of pathogens on their evolution. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Critical evaluation of solid waste sample processing for DNA-based microbial community analysis

BIODEGRADATION, 22(1), 189–204.

By: B. Staley*, P. Saikaly *, F. Reyes n & M. Barlaz n 

author keywords: Landfill; Solid waste; Refuse; T-RFLP; Sample processing; Bias
MeSH headings : Archaea / genetics; Archaea / metabolism; Bacteria / genetics; Bacteria / metabolism; Biodegradation, Environmental; DNA, Archaeal / genetics; DNA, Archaeal / isolation & purification; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Polymorphism, Restriction Fragment Length; Refuse Disposal / methods
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Toward identifying the next generation of superfund and hazardous waste site contaminants

Environmental Health Perspectives, 119(1), 6–10.

By: W. Ela, D. Sedlak, M. Barlaz , H. Henry, D. Muir, D. Swackhamer, E. Weber, R. Arnold ...

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Top-down control analysis of the cadmium effects on molluscan mitochondria and the mechanisms of cadmium-induced mitochondrial dysfunction

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 300(1), R21–R31.

By: I. Kurochkin*, M. Etzkorn *, D. Buchwalter n, L. Leamy* & I. Sokolova *

author keywords: cadmium; reactive oxygen species; proton leak; substrate oxidation; mitovite
MeSH headings : Adenosine Triphosphate / metabolism; Adenosine Triphosphate / pharmacology; Animals; Antioxidants / pharmacology; Cadmium / pharmacology; Crassostrea / physiology; Mitochondria / drug effects; Mitochondria / physiology; Models, Animal; Organophosphorus Compounds / pharmacology; Phosphorylation / drug effects; Reactive Oxygen Species / metabolism; Ubiquinone / pharmacology
TL;DR: Data suggest that Cd-induced decrease of mitochondrial efficiency and ATP production are predominantly driven by the high sensitivity of substrate oxidation and proton leak subsystems to this metal. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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