Center for Environmental and Health Effects of PFAS

Works Published in 2020

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Displaying works 81 - 99 of 99 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2020 journal article

CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity

ENVIRONMENTAL HEALTH PERSPECTIVES, 128(2).

By: K. Mansouri*, N. Kleinstreuer*, A. Abdelaziz*, D. Alberga*, V. Alves*, P. Andersson*, C. Andrade*, F. Bai* ...

MeSH headings : Androgens; Computer Simulation; Databases, Factual; Endocrine Disruptors; High-Throughput Screening Assays; Humans; Receptors, Androgen; United States; United States Environmental Protection Agency
TL;DR: The Collaborative Modeling Project for Androgen Receptor Activity (CoMPARA) efforts are described, which follows the steps of the Collaborative Estrogen Recept Activity Prediction Project (CERAPP). (via Semantic Scholar)
Source: Web Of Science
Added: March 30, 2020

2020 review

Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease

[Review of ]. NEUROPSYCHOPHARMACOLOGY, 45(7), 1086–1096.

By: J. Hollander*, D. Cory-Slechta*, F. Jacka*, S. Szabo*, T. Guilarte*, S. Bilbo*, C. Mattingly n, S. Moy* ...

MeSH headings : Environmental Exposure / adverse effects; Humans; Mental Disorders / etiology
Sources: Web Of Science, ORCID
Added: March 30, 2020

2020 journal article

Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function

ARCHIVES OF TOXICOLOGY, 94(2), 469–484.

By: M. Kosnik n, J. Strickland*, S. Marvel n, D. Wallis n, K. Wallace*, A. Richard*, D. Reif n, T. Shafer*

author keywords: Neurotoxicity; Screening; ToxCast
MeSH headings : Animals; Cell Culture Techniques / instrumentation; Cell Culture Techniques / methods; Databases, Chemical; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical / methods; Machine Learning; Microelectrodes; Nerve Net / drug effects; Neural Networks, Computer; Neurons / drug effects; Neurotoxicity Syndromes / pathology; Rats, Long-Evans; Toxicity Tests / methods
TL;DR: It is demonstrated that multivariate MEA activity patterns can efficiently screen for diverse chemical activities relevant to neurotoxicity, and that response patterns may have predictive value related to chemical structural features. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID
Added: March 30, 2020

2020 journal article

Hierarchical Quantitative Structure-Activity Relationship Modeling Approach for Integrating Binary, Multiclass, and Regression Models of Acute Oral Systemic Toxicity

CHEMICAL RESEARCH IN TOXICOLOGY, 33(2), 353–366.

MeSH headings : Administration, Oral; Algorithms; Animals; Models, Molecular; Molecular Structure; Organic Chemicals / administration & dosage; Organic Chemicals / toxicity; Quantitative Structure-Activity Relationship; Rats; Regression Analysis
TL;DR: A novel, dual-layer hierarchical modeling method to fully integrate regression and classification QSAR models for assessing rat acute oral systemic toxicity, with respect to regulatory classifications of concern is presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 30, 2020

2020 journal article

Assessing the Effectiveness of Point-of-Use Residential Drinking Water Filters for Perfluoroalkyl Substances (PFASs)

ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 7(3), 178–184.

By: N. Herkert*, J. Merrill n, C. Peters*, D. Bollinger*, S. Zhang*, K. Hoffman*, P. Ferguson*, D. Knappe n, H. Stapleton*

UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: March 30, 2020

2020 journal article

GAC to BAC: Does it make chloraminated drinking water safer?

WATER RESEARCH, 172.

By: A. Cuthbertson*, S. Kimura*, H. Liberatore*, D. Knappe n, B. Stanford*, R. Summers*, E. Dickenson*, J. Maness n ...

author keywords: Biological activated carbon; Drinking water; Disinfection by-products; GAC; Total organic halogen; Calculated cytotoxicity & genotoxicity
MeSH headings : Charcoal; Disinfectants; Disinfection; Drinking Water; Halogenation; Trihalomethanes; Water Pollutants, Chemical; Water Purification
TL;DR: While calculated genotoxicity decreased in all filters, decreases in overall DBP formation did not correlate with decreases in calculated cytotoxicity, highlighting that DBP concentration alone may not always provide an adequate basis for risk assessment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: March 23, 2020

2020 journal article

Rapid Characterization of Per- and Polyfluoroalkyl Substances (PFAS) by Ion Mobility Spectrometry-Mass Spectrometry (IMS-MS)

Analytical Chemistry, 92(6), 4427–4435.

MeSH headings : Hydrocarbons, Fluorinated / analysis; Ion Mobility Spectrometry; Mass Spectrometry; Molecular Structure; Polymers / analysis
TL;DR: Results from this study show that the IMS separation provides novel information to support traditional LC-MS PFAS analyses and will greatly benefit the evaluation of unknown pollutants in future environmental studies. (via Semantic Scholar)
Sources: ORCID, Web Of Science
Added: March 23, 2020

2020 journal article

Coupling IR-MALDESI with Drift Tube Ion Mobility-Mass Spectrometry for High-Throughput Screening and Imaging Applications

Journal of the American Society for Mass Spectrometry, 31(3), 642–650.

By: M. Ekelöf n, J. Dodds n, S. Khodjaniyazova n, K. Garrard n, E. Baker n & D. Muddiman n

author keywords: mass spectrometry imaging; ion mobility spectrometry; IR-MALDESI; high-throughput; isomer resolution
TL;DR: To increase a range of detectable features in IR-MALDESI experiments, the home-built ion source was integrated with a commercially available drift tube ion mobility spec-trometer-mass spectrometer (IMS-MS) and analyzed small polar molecules, lipids, carbohydrates as well as intact proteins. (via Semantic Scholar)
Sources: Crossref, ORCID, Web Of Science
Added: March 23, 2020

2020 journal article

Degradation Model for the Tensile Strength of PVC and Rubber Gasket Materials Exposed to Benzene and PCE-Saturated Aqueous Solutions

TRANSPORTATION RESEARCH RECORD, 2674(2), 274–283.

By: P. Hosseini n, S. Alhomair n, Z. Faeli n, M. Pour-Ghaz n, M. Gabr n, D. Knappe n, C. Parker

UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID
Added: March 10, 2020

2020 journal article

Three-Dimensional Imaging with Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 31(2), 292–297.

By: H. Bai n, S. Khodjaniyazova n, K. Garrard n & D. Muddiman n

author keywords: mass spectrometry imaging; 3D; IR-MALDESI; MUPS; HRAM
MeSH headings : Anti-Ulcer Agents / analysis; Citrates / analysis; Imaging, Three-Dimensional / methods; Omeprazole / analysis; Pharmaceutical Preparations / chemistry; Proton Pump Inhibitors / analysis; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Starch / analysis; Tablets, Enteric-Coated / chemistry
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID
Added: March 10, 2020

2020 journal article

Determination of Optimal Electrospray Parameters for Lipidomics in Infrared-Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 31(2), 319–325.

By: M. Bagley n, M. Ekelof n & D. Muddiman n

author keywords: IR-MALDESI; mass spectrometry imaging: electrospray ionization; metabolites; lipids
MeSH headings : Animals; Lipidomics / methods; Lipids / analysis; Liver / chemistry; Liver / diagnostic imaging; Molecular Imaging / methods; Rats; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: Using these defined parameters, IR-MALDESI positive polarity lipidomics studies can increase lipid abundances 3-fold, with 15% greater coverage, while an abundance increase of 1.5-fold and 10% more coverage can be achieved relative to commonly used parameters in negative polarity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID
Added: March 10, 2020

2020 journal article

Development of a relative quantification method for infrared matrix-assisted laser desorption electrospray ionization mass spectrometry imaging of Arabidopsis seedlings

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 34(6).

By: M. Bagley n, A. Stepanova n, M. Ekelof n, J. Alonso n & D. Muddiman n

MeSH headings : Arabidopsis / chemistry; Arabidopsis / genetics; Arabidopsis Proteins / genetics; Indoleacetic Acids / analysis; Indoles / analysis; Mutation; Oximes / analysis; Oxygenases / genetics; Seedlings / chemistry; Seedlings / genetics; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: IAA doping of agarose was demonstrated as a viable technique for relative quantification of metabolites in live seedlings or tissues with similar biological considerations and was shown to be an appropriate sampling surface for IR-MALDESI mass spectrometry imaging of Arabidopsis seedlings. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: March 10, 2020

2020 journal article

Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxatilis) are associated with biomarkers of altered immune and liver function

ENVIRONMENT INTERNATIONAL, 136.

By: T. Guillette n, J. McCord*, M. Guillette n, M. Polera n, K. Rachels*, C. Morgeson*, N. Kotlarz n, D. Knappe n ...

Contributors: T. Guillette n, J. McCord*, M. Guillette n, M. Polera n, K. Rachels*, C. Morgeson*, N. Kotlarz n, D. Knappe n ...

MeSH headings : Animals; Bass; Biomarkers; Fluorocarbons / toxicity; Liver; Rivers; Water Pollutants, Chemical / toxicity
TL;DR: The elevated PFAS concentrations found in the Cape Fear River Striped Bass were associated with biomarkers of alterations in the liver and immune system, and correlations betweenPFAS concentrations and health-related serum biomarkers were evaluated. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: March 2, 2020

2020 journal article

HGBEnviroScreen: Enabling Community Action through Data Integration in the Houston–Galveston–Brazoria Region

International Journal of Environmental Research and Public Health, 17(4), 1130.

By: S. Bhandari*, P. Lewis*, E. Craft*, S. Marvel n, D. Reif n & W. Chiu*

author keywords: environmental justice; geographic information systems; vulnerable populations; community; public health; data; screening; enviroscreen
MeSH headings : Accidents, Occupational; Community Participation; Disasters; Environmental Exposure; Floods; Humans; Public Health; Risk Assessment; Risk Factors; Vulnerable Populations
TL;DR: HGBEnviroScreen is not only helping identify communities of greatest overall vulnerability but is also providing insights into which domains would most benefit from improved planning, policy, and action in order to reduce future vulnerability. (via Semantic Scholar)
Source: ORCID
Added: February 15, 2020

2020 chapter

Chapter 19 - Immunology

In The Zebrafish in Biomedical Research.

Jeff Yoder

UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: December 20, 2019

2020 journal article

Investigating host-pathogen meta-metabolic interactions of Magnaporthe oryzae infected barley using infrared matrix-assisted laser desorption electrospray ionization mass spectrometry

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 412(1), 139–147.

By: J. Kalmar n, Y. Oh n, R. Dean n & D. Muddiman n

author keywords: IR-MALDESI; Mass spectrometry imaging; Orbitrap; Magnaporthe oryzae; Image recognition; Polarity switching
MeSH headings : Hordeum / metabolism; Hordeum / microbiology; Host-Pathogen Interactions; Infrared Rays; Magnaporthe / metabolism; Magnaporthe / physiology; Metabolomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: Serotonin, a barley defense metabolite, was a compound identified in both positive and negative modes, and metabolites in the melanin pathway, important for infection development of M. oryzae were identified but were unable to be confirmed with MS/MS due to their low abundances. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: December 9, 2019

2020 article

Utilizing Drift Tube Ion Mobility Spectrometry for the Evaluation of Metabolites and Xenobiotics

ION MOBILITY-MASS SPECTROMETRY: METHODS AND PROTOCOLS, Vol. 2084, pp. 35–54.

By: M. Odenkirk n & E. Baker n

Contributors: M. Odenkirk n & E. Baker n

author keywords: Ion mobility spectrometry (IMS); Drift tube ion mobility spectrometry (DTIMS); Metabolomics; Exposomics; Collision cross section (CCS)
MeSH headings : Ion Mobility Spectrometry / methods; Metabolome; Metabolomics / methods; Xenobiotics / analysis
TL;DR: A review of relevant parameter considerations for DTIMS application with emphasis on xenobiotics and metabolomics isomer separations is presented. (via Semantic Scholar)
Sources: ORCID, Web Of Science
Added: December 5, 2019

2020 journal article

Inappropriate Citation of Vaccine Article

The Journal of Infectious Diseases, 222(8), 1413–1414.

By: D. Reif n, S. Chanock*, K. Edwards* & J. Crowe*

MeSH headings : Humans; Smallpox; Vaccination; Vaccines / adverse effects
UN Sustainable Development Goal Categories
Source: ORCID
Added: July 9, 2019

2020 journal article

Water temperature interacts with the insecticide imidacloprid to alter acute lethal and sublethal toxicity to mayfly larvae

NEW ZEALAND JOURNAL OF MARINE AND FRESHWATER RESEARCH, 54(1), 115–130.

author keywords: Neonicotinoids; pesticides; freshwater; synergism; ecotoxicology; climate change
TL;DR: Investigating the individual and interactive effects of water temperature and imidacloprid on larvae of two New Zealand mayflies suggests that developing a more thorough understanding of temperature-contaminant interactions may be important to allow better protection of aquatic ecosystems. (via Semantic Scholar)
Source: Web Of Science
Added: June 17, 2019

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