Center for Environmental and Health Effects of PFAS

Works Published in 2005

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Displaying works 1 - 20 of 67 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2005 conference paper

Effects of sorbent structure and chemistry on organic contaminant sorption: Activated carbon perspective

ACS, Division of Environmental Chemistry - Preprints of Extended Abstracts, 45(2), 426–432. http://www.scopus.com/inward/record.url?eid=2-s2.0-32244435339&partnerID=MN8TOARS

By: D. Knappe

Contributors: D. Knappe

Source: ORCID
Added: September 9, 2023

2005 book

Effectiveness of high-silica zeolites for the adsorption of methyl tertiary-butyl ether from natural water

In Water Science and Technology: Water Supply (Vol. 5, pp. 83–91). http://www.scopus.com/inward/record.url?eid=2-s2.0-31144448170&partnerID=MN8TOARS

By: D. Knappe & A. Campos

Contributors: D. Knappe & A. Campos

Source: ORCID
Added: September 9, 2023

2005 journal article

2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Induces Organ- Specific Differential Gene Expression in Male Japanese Medaka (Oryzias latipes)

Toxicological Sciences, 85(1), 572–584.

By: D. Volz*, D. Bencic, D. Hinton, J. Law & S. Kullman*

author keywords: Japanese medaka; TCDD; gene expression; brain; liver; testis
MeSH headings : Animals; Brain / drug effects; Brain / metabolism; Brain / pathology; Environmental Pollutants / toxicity; Gene Expression / drug effects; Gene Expression Profiling; Injections, Intraperitoneal; Liver / drug effects; Liver / metabolism; Liver / pathology; Male; Oligonucleotide Array Sequence Analysis; Organ Specificity; Oryzias / genetics; Polychlorinated Dibenzodioxins / toxicity; Reverse Transcriptase Polymerase Chain Reaction; Testis / drug effects; Testis / metabolism; Testis / pathology
TL;DR: In this study, suppression subtractive hybridization was exploited as a screening tool to assess qualitative gene expression changes in whole brain, liver, and testis of adult male Japanese medaka exposed for 48 h to a single intraperitoneal-injected dose of TCDD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, ORCID
Added: September 15, 2022

2005 conference paper

The Application of Life-Cycle Analysis to Integrated Solid Waste Management

Presented at the Association of Environmental Engineering and Science Professors (AEESP) Frontiers Conference, Potsdam, NY.

By: P. Kaplan, M. Barlaz & S. Ranjithan

Event: Association of Environmental Engineering and Science Professors (AEESP) Frontiers Conference at Potsdam, NY on July 25-27, 2005

Source: NC State University Libraries
Added: February 27, 2022

2005 conference paper

Assessment of the Behavior of Chemical Warfare Agents in Landfills

Presented at the Solid Waste Association of North America (SWANA) Landfill Symposium, Boulder, CO.

By: M. Barlaz, S. Bartelt-Hunt, D. Knappe & P. Kjeldsen

Event: Solid Waste Association of North America (SWANA) Landfill Symposium at Boulder, CO on June 6-9, 2005

Source: NC State University Libraries
Added: February 27, 2022

2005 journal article

Reproducibility of Retention Time using a Splitless nanoLC Coupled to an ESI-FTICR Mass Spectrometer

Journal of Biomolecular Techniques, 16, 4, 414–422.

By: D. Muddiman, C. Mason & K. Johnson

Source: NC State University Libraries
Added: March 17, 2021

2005 journal article

Rapid estrogenic regulation of extracellular signal-regulated kinase 1/2 signaling in cerebellar granule cells involves a G protein- and protein kinase A-dependent mechanism and intracellular activation of protein phosphatase 2A

Endocrinology, 146(12), 5397–5406.

By: S. Belcher*, H. Le*, L. Spurling* & J. Wong*

Contributors: S. Belcher*, H. Le*, L. Spurling* & J. Wong*

MeSH headings : Animals; Cells, Cultured; Cerebellum / cytology; Cerebellum / metabolism; Cyclic AMP-Dependent Protein Kinases / physiology; Enzyme Activation / physiology; Estradiol / pharmacology; Estrogens / physiology; Extracellular Signal-Regulated MAP Kinases / metabolism; Female; GTP-Binding Proteins / physiology; Intracellular Membranes / enzymology; Male; Mitogen-Activated Protein Kinase 1 / metabolism; Mitogen-Activated Protein Kinase 3 / metabolism; Neurons / metabolism; Pertussis Toxin / pharmacology; Phosphoprotein Phosphatases / metabolism; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Signal Transduction / drug effects; Signal Transduction / physiology; Time Factors
TL;DR: The presented evidence indicates that the rapid effects of estrogens on ERK signaling in cerebellar granule cells are induced through a novel G protein-coupled receptor mechanism that requires PKA and Src-kinase activity to link E(2) to the ERK/MAPK signaling module. (via Semantic Scholar)
Source: ORCID
Added: March 5, 2021

2005 journal article

Ontogeny of rapid estrogen-mediated extracellular signal-regulated kinase signaling in the rat cerebellar cortex: Potent nongenomic agonist and endocrine disrupting activity of the xenoestrogen bisphenol A

Endocrinology, 146(12), 5388–5396.

By: A. Zsarnovszky*, H. Le*, H. Wang* & S. Belcher*

Contributors: A. Zsarnovszky*, H. Le*, H. Wang* & S. Belcher*

MeSH headings : Aging / metabolism; Animals; Animals, Newborn; Benzhydryl Compounds; Cerebellar Cortex / enzymology; Dose-Response Relationship, Drug; Drug Combinations; Endocrine System / drug effects; Estradiol / administration & dosage; Estradiol / pharmacology; Estrogens, Non-Steroidal / administration & dosage; Estrogens, Non-Steroidal / pharmacology; Extracellular Signal-Regulated MAP Kinases / metabolism; Female; Immunohistochemistry; Male; Phenols / administration & dosage; Phenols / pharmacology; Rats; Rats, Sprague-Dawley; Signal Transduction / drug effects
TL;DR: It is shown that ERK1/2 signaling in the cerebellum of neonatal and mature rats was rapidly responsive to E(2) and during development to the environmental estrogen bisphenol A (BPA) and the ability of BPA to act as a highly potent E( 2) mimetic and to also disrupt the rapid actions of E(3) at very low concentrations during cerebellar development highlights the potential low-dose impact of xenoestrogens on the developing (via Semantic Scholar)
Source: ORCID
Added: March 5, 2021

2005 journal article

Nucleic Acid Analysis by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry at the Beginning of the Twenty-First Century

Current Pharmaceutical Design, 11(20), 2593–2613.

By: J. Frahm & D. Muddiman*

author keywords: FT-ICR; Fourier transform ion cyclotron resonance; mass spectrometry; DNA; RNA; PNA
MeSH headings : Nucleic Acids / analysis; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Electrospray Ionization / trends; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / trends; Spectroscopy, Fourier Transform Infrared / methods; Spectroscopy, Fourier Transform Infrared / trends; Spectrum Analysis / methods; Spectrum Analysis / trends; Technology, Pharmaceutical / instrumentation; Technology, Pharmaceutical / methods; Technology, Pharmaceutical / trends
TL;DR: A diverse range of studies including fundamental studies of nucleic acid properties, improvements in sample clean up and preparation, better methods to obtain higher mass measurement accuracy, analysis of noncovalent complexes, tandem mass spectrometry, and characterization of peptide nucleic acids are presented. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021

2005 journal article

Primary Trabecular Meshwork Cells Incubated in Human Aqueous Humor Differ from Cells Incubated in Serum Supplements

Investigative Opthalmology & Visual Science, 46(8), 2848.

By: M. Fautsch, K. Howell, A. Vrabel, M. Charlesworth*, D. Muddiman* & D. Johnson

MeSH headings : Adult; Aged; Aged, 80 and over; Aqueous Humor / physiology; Ascorbic Acid / metabolism; Ascorbic Acid / pharmacology; Blotting, Western; Cell Culture Techniques; Cell Proliferation; Culture Media; Cytoskeletal Proteins / metabolism; Dexamethasone / pharmacology; Electrophoresis, Gel, Two-Dimensional; Eye Proteins / metabolism; Female; Glycoproteins / metabolism; Humans; Infant; Male; Middle Aged; Serum; Tissue Inhibitor of Metalloproteinase-1 / metabolism; Trabecular Meshwork / cytology; Trabecular Meshwork / drug effects; Trabecular Meshwork / metabolism
TL;DR: Addition of human aqueous humor rather than FBS to trabecular monolayer cell cultures triggers significant changes in cellular and molecular characteristics. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021

2005 journal article

Impact of urine preservation methods and duration of storage on measured levels of environmental contaminants

Journal of Exposure Science & Environmental Epidemiology, 16(1), 39–48.

By: J. Hoppin*, R. Ulmer*, A. Calafat*, D. Barr*, S. Baker*, H. Meltzer*, K. Rønningen*

author keywords: sample storage and shipment; cohort studies; analytical chemistry; urine
MeSH headings : Environmental Exposure; Environmental Pollutants / urine; Humans; Mass Spectrometry; Reproducibility of Results; Specimen Handling; Temperature; Time Factors; Urinalysis / methods
TL;DR: In general, most analytes were stable under all conditions with changes in mean concentration over time, temperature, and preservative being generally less than 20%, with the exception of the OP metabolites in the presence of boric acid. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 21, 2021

2005 journal article

Quantitative Protein Expression Analysis Of CLL B Cells from Mutated and Unmutated IgVHSubgroups Using Acid-Cleavable Isotope-Coded Affinity Tag Reagents

Journal of Proteome Research, 4(4), 1310–1317.

By: D. Barnidge*, D. Jelinek*, D. Muddiman* & N. Kay*

author keywords: CLL; B cell; quantitative comparison; clCAT; UM-CLL; M-CLL; linear ion trap mass spectrometer
MeSH headings : B-Lymphocytes / chemistry; B-Lymphocytes / immunology; Cell Fractionation; Genes, Immunoglobulin; Humans; Immunoglobulin Heavy Chains / genetics; Immunoglobulin Heavy Chains / immunology; Immunoglobulin Variable Region / genetics; Immunoglobulin Variable Region / immunology; Isotope Labeling / methods; Leukemia, Lymphocytic, Chronic, B-Cell / immunology; Mass Spectrometry / methods; Mutation; Proteome / analysis
TL;DR: Stable isotope labeling and mass spectrometry can complement 2D gel electrophoresis and gene microarray technologies for identifying putative and perhaps unique prognostic markers in CLL. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 18, 2021

2005 journal article

Feasibility of using subject-collected dust samples in epidemiological and clinical studies of indoor allergens

Journal of Allergy and Clinical Immunology, 115(2), S97.

By: M. Sever*, S. Arbes*, B. Vaughn*, J. Mehta*, J. Lynch*, H. Mitchell*, J. Hoppin*, H. Spencer*, D. Sandler*, D. Zeldin*

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: September 10, 2020

2005 journal article

Substructural fragments: an universal language to encode reactions, molecular and supramolecular structures

Journal of Computer-Aided Molecular Design, 19(9-10), 693–703.

author keywords: chemical reactions; clustering; condensed graphs of reactions; exchange of information; hydrogen bonds; QSPR; similarity; solubility; substructural fragments
MeSH headings : Computer Simulation; Hydrogen Bonding; Macromolecular Substances; Models, Chemical; Molecular Structure; Quantitative Structure-Activity Relationship; Solubility; Thermodynamics; Water
TL;DR: Substructural fragments are proposed as a simple and safe way to encode molecular structures in a matrix containing the occurrence of fragments of a given type and the knowledge retrieved from QSPR modelling can also be stored in that matrix in addition to the information about fragments. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2005 journal article

Mutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortion

Proceedings of the National Academy of Sciences, 102(9), 3342–3347.

MeSH headings : Animals; Base Sequence; Chromosomes, Artificial, Bacterial; DNA; Haplotypes; Infertility, Male / genetics; Male; Mice; Molecular Sequence Data; Mutation; Nerve Tissue Proteins / genetics; Phosphoric Monoester Hydrolases / genetics; Reverse Transcriptase Polymerase Chain Reaction
TL;DR: Results uncouple the proximal t haplotype sterility locus, S1, from TRD, demonstrating that S1 and the proximate distorter loci, D1, are not the same gene. (via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020

2005 journal article

Resolving mechanisms of toxicity while pursuing ecotoxicological relevance?

Marine Pollution Bulletin, 51(8-12), 635–648.

By: D. Hinton*, S. Kullman*, R. Hardman*, D. Volz*, P. Chen*, M. Carney*, D. Bencic*

MeSH headings : Animals; Animals, Genetically Modified / metabolism; Carcinogenicity Tests / methods; Ecology / methods; Endocrine Disruptors / metabolism; Environmental Pollutants / metabolism; Models, Animal; Oligonucleotide Array Sequence Analysis / methods; Toxicology / methods; Toxicology / trends
TL;DR: Studies resolving mechanisms of toxicity are reviewed and ways to address biocomplexity, mixtures of contaminants, and the need to relate individual level responses to populations and communities are discussed. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020

2005 journal article

Functional characterization of medaka CYP3A38 and CYP3A40: Kinetics and catalysis by expression in a recombinant baculovirus system

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 141(4), 338–348.

By: S. Kashiwada*, D. Hinton* & S. Kullman*

author keywords: medaka; CYP3A; baculovirus; cytochrome P450; kinetics; testosterone; BFC; metabolism
MeSH headings : Amino Acid Sequence; Animals; Baculoviridae / genetics; Catalysis; Cytochrome P-450 CYP3A / chemistry; Cytochrome P-450 CYP3A / metabolism; Kinetics; Molecular Sequence Data; Oryzias / metabolism; Oxazines / metabolism; Recombinant Proteins / metabolism; Testosterone / metabolism
TL;DR: Describing the catalytic and kinetic activities of two medaka CYP3A paralogs with benzyloxyresorufin (BFC), a fluorescent 3A-selective substrate, and testosterone suggests that differences in kinetics and catalytic activities are a result of amino acid substitutions in SRS regions 1, 3 and 5 within the CYP1A38 and CYP2A40 protein sequence. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020

2005 journal article

Differences in Dissolved Cadmium and Zinc Uptake among Stream Insects:  Mechanistic Explanations

Environmental Science & Technology, 39(2), 498–504.

MeSH headings : Animals; Biological Availability; Cadmium / pharmacokinetics; Insecta; Kinetics; Solubility; Tissue Distribution; Water Pollutants / pharmacokinetics; Zinc / pharmacokinetics
TL;DR: Comparing dissolved Cd and Zn uptake rates in several aquatic insect species demonstrated that species vary widely in these processes, suggesting that these metals are transported by similar mechanisms. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2005 journal article

Mapping Sites of Protein Phosphorylation by Mass Spectrometry Utilizing a Chemical-Enzymatic Approach:  Characterization of Products from α-S1Casein Phosphopeptides

Journal of Proteome Research, 4(2), 424–434.

author keywords: chemical-enzymatic; phosphorylation; 2-aminoethanethiol; isotope dilution mass spectrometry; phosphoproteins; phosphopeptides; quantification
MeSH headings : Amino Acid Sequence; Animals; Caseins / metabolism; Cattle; Molecular Sequence Data; Peptide Fragments / metabolism; Phosphopeptides / metabolism; Phosphorylation; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR: ESI-TOF mass spectrometry was used to characterize products from the chemical-enzymatic cleavage of specific phosphorylation sites in bovine alpha-S1 casein and synthetic phosphopeptides containing substitutions at a single phosphorylated site. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 28, 2020

2005 journal article

Protein expression profiling of CLL B cells using replicate off-line strong cation exchange chromatography and LC–MS/MS

Journal of Chromatography B, 819(1), 33–39.

By: D. Barnidge*, R. Tschumper*, D. Jelinek*, D. Muddiman* & N. Kay*

author keywords: CLL; 2D-LC-MS/MS; B cell; expression profiling; off-line SCX; reproducibility
MeSH headings : Antigens, CD / isolation & purification; B-Lymphocytes / metabolism; Blood Proteins / isolation & purification; Cell Fractionation; Cell Membrane / chemistry; Chromatography, Ion Exchange / methods; Chromatography, Liquid / methods; Gene Expression Profiling / methods; Humans; Leukemia, Lymphocytic, Chronic, B-Cell / metabolism; Mass Spectrometry / methods; Neoplasm Proteins / blood
TL;DR: Examination of crude membranes from B cells derived from a patient with chronic lymphocytic leukemia to examine the protein expression profile of CLL B cells shows an overlap of 64% between proteins identified in replicate runs was achieved for this system. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 28, 2020

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