Center for Environmental and Health Effects of PFAS

Works Published in 2021

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Displaying works 1 - 20 of 74 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2021 journal article

Response to “Comment on Scientific Basis for Managing PFAS as a Chemical Class”

Response to “Comment on Scientific Basis for Managing PFAS as a Chemical Class.” Environmental Science & Technology Letters, 8(2), 195–197.

Source: ORCID
Added: September 9, 2023

2021 journal article

Longitudinal assessment of point‐of‐use carbon filters for removal of per‐ and polyfluoroalkyl substances from private well water

AWWA Water Science, 3(6).

By: R. Mulhern*, N. Bynum*, C. Liyanapatirana*, N. DeStefano n, D. Knappe n & J. Gibson*

UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: September 9, 2023

2021 journal article

Gestational Phthalate Exposure and Preschool Attention Deficit Hyperactivity Disorder in Norway

ENVIRONMENTAL EPIDEMIOLOGY, 5(4).

By: E. Kamai*, G. Villanger*, R. Nethery*, C. Thomsen*, A. Sakhi*, S. Drover*, J. Hoppin n, G. Knudsen* ...

author keywords: phthalates; ADHD; Attention Deficit Hyperactivity Disorder; biomarkers; prenatal; gestational; MoBa; The Norwegian Mother; Father and Child Cohort Study
TL;DR: Results suggest gestational phthalate exposure may impact the behavior of children as young as 3 years, and boys, but not girls, mono-n-butyl phthalates exposure was associated with increased odds of ADHD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID
Added: May 16, 2022

2021 journal article

Improving the Speed and Selectivity of Newborn Screening Using Ion Mobility Spectrometry-Mass Spectrometry

ANALYTICAL CHEMISTRY, 93(51), 17094–17102.

By: J. Dodds n & E. Baker n

MeSH headings : Biomarkers; High-Throughput Screening Assays; Humans; Infant, Newborn; Ion Mobility Spectrometry; Mass Spectrometry; Neonatal Screening
TL;DR: The utility of ion mobility spectrometry (IMS) to enhance the accuracy of MS assays for primary (tier 1) screening is explored and the results suggest that ∼400 IMS resolving power would be required to confidently assess most NBS biomarkers of interest in dried blood spots (DBSs) that currently require follow-up testing. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 7, 2022

2021 review

Recommendations for good practice in MS-based lipidomics

[Review of ]. JOURNAL OF LIPID RESEARCH, 62.

author keywords:   lipidomics; metabolomics; MS; chromatography; ion mobility spectrometry; phospholipids; sphingolipids; LC-MS; lipid identification
MeSH headings : Humans; Lipidomics / standards; Lipids / analysis; Mass Spectrometry
TL;DR: It is the intention of this review to highlight the most quality-relevant aspects of the lipidomics workflow, including preanalytics, sample preparation, MS, and lipid species identification and quantitation. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 7, 2022

2021 journal article

Vitamin D deficiency promotes accumulation of bioactive lipids and increased endocannabinoid tone in zebrafish

JOURNAL OF LIPID RESEARCH, 62.

author keywords: MS; metabolomics; lipidomics; lipids; nutrition; endocannabinoid biosynthesis; MSI; IR-MALDESI; anandamide
MeSH headings : Animals; Endocannabinoids / metabolism; Lipid Metabolism; Lipids / chemistry; Vitamin D Deficiency / metabolism; Zebrafish
TL;DR: Investigation of putative linkages between vitamin D deficiency and metabolic disruption of bioactive lipids by MS imaging and expression of genes involved in EC biosynthesis, metabolism, and receptor signaling in adipose tissue and liver suggest that VDD may promote accumulation of bio active lipids and increased EC tone in zebrafish. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 7, 2022

2021 journal article

TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA

NUCLEIC ACIDS RESEARCH, 49(22), 13000–13018.

By: P. Kaur n, R. Barnes*, H. Pan n, A. Detwiler*, M. Liu n, C. Mahn n, J. Hall n, Z. Messenger n ...

MeSH headings : Animals; DNA / chemistry; DNA / genetics; DNA / metabolism; HeLa Cells; Humans; Mice, Inbred C57BL; Microscopy, Atomic Force; Nucleic Acid Conformation; Protein Binding; Shelterin Complex / genetics; Shelterin Complex / metabolism; Telomere / genetics; Telomere / metabolism; Telomere-Binding Proteins / genetics; Telomere-Binding Proteins / metabolism; Telomeric Repeat Binding Protein 2 / genetics; Telomeric Repeat Binding Protein 2 / metabolism
TL;DR: A molecular model in which TIN2 functions as an architectural protein to promote TRF2-mediated trans and cis higher-order nucleic acid structures at telomeres is proposed. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: January 18, 2022

2021 journal article

Enhancing Metabolomic Coverage in Positive Ionization Mode Using Dicationic Reagents by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

METABOLITES, 11(12).

By: Y. Xi n & D. Muddiman n

author keywords: metabolites; dicationic reagent; ambient ionization; IR-MALDESI; mass spectrometry imaging
Sources: Web Of Science, ORCID
Added: January 10, 2022

2021 personal communication

From IgZ to IgT: A Call for a Common Nomenclature for Immunoglobulin Heavy Chain Genes of Ray-Finned Fish

Dornburg, A., Ota, T., Criscitiello, M. F., Salinas, I., Sunyer, J. O., Magadan, S., … Yoder, J. A. (2021, December 1).

By: A. Dornburg*, T. Ota*, M. Criscitiello*, I. Salinas*, J. Sunyer*, S. Magadan*, P. Boudinot*, Z. Xu* ...

MeSH headings : Animals; Fish Proteins / genetics; Fishes / genetics; Genes, Immunoglobulin Heavy Chain; Phylogeny; Terminology as Topic; Zebrafish / genetics
TL;DR: Ray-finned fishes comprise more than half the *60,000 known vertebrate species, and are pivotal to the functionality of aquatic ecosystems and success of global multibillion dollar industries, necessitates that immunology and translational medicine research groups investigating the immune system in one or a number of species employ a common language for describing homologous immune components. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: January 10, 2022

2021 article

Environmental exposures contribute to respiratory and allergic symptoms among women living in the banana growing regions of Costa Rica

Alhanti, B., Joode, B. van W., Martinez, M. S., Mora, A. M., Gamboa, L. C., Reich, B., … Hoppin, J. A. (2021, December 30). OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, Vol. 12.

By: B. Alhanti n, B. Joode*, M. Martinez*, A. Mora*, L. Gamboa*, B. Reich n, C. Lindh*, M. Lepiz*, J. Hoppin n

author keywords: asthma; respiratory disease; allergy; pesticide; agriculture
MeSH headings : Asthma / epidemiology; Cohort Studies; Costa Rica / epidemiology; Eczema / epidemiology; Environmental Exposure / adverse effects; Exanthema / epidemiology; Female; Humans; Hypersensitivity / epidemiology; Musa; Pesticides / adverse effects; Respiratory Tract Diseases / epidemiology; Rhinitis / epidemiology; Smoke / adverse effects
TL;DR: Findings suggest that environmental exposure to both pesticides and smoke may impact respiratory and skin-related allergic outcomes in women. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: January 10, 2022

2021 article

The evolution of innate immune receptors: investigating the diversity, distribution, and phylogeny of immune recognition across eukaryotes

Buckley, K. M., & Yoder, J. A. (2021, December 15). IMMUNOGENETICS, Vol. 12.

MeSH headings : Eukaryota; Evolution, Molecular; Immunity, Innate / genetics; Phylogeny; Receptors, Immunologic
TL;DR: The diversity of IIRs from plants, vertebrates, invertebrate deuterostomes, a range of protostome invertebrates and basal metazoans is explored, and it is suggested that, to fully understand eukaryotic immune systems, further investigations of these proteins are warranted. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: January 3, 2022

2021 journal article

Regulatory status of pesticide residues in cannabis: Implications to medical use in neurological diseases

CURRENT RESEARCH IN TOXICOLOGY, 2, 140–148.

By: D. Pinkhasova*, L. Jameson*, K. Conrow*, M. Simeone*, A. Davis n, T. Wiegers n, C. Mattingly n, M. Leung*

author keywords: Cannabis; Pesticide; Database; Regulation; Seizure; Contaminant
TL;DR: Network analysis reveals potential interactions of insecticides, cannabinoids, and seizure at a functional level in cannabis. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: January 3, 2022

2021 journal article

Predicting molecular mechanisms, pathways, and health outcomes induced by Juul e-cigarette aerosol chemicals using the Comparative Toxicogenomics Database

CURRENT RESEARCH IN TOXICOLOGY, 2, 272–281.

author keywords: E-cigarettes; Vaping; Juul; Respiratory disease; Database; Environmental exposure
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: January 3, 2022

2021 journal article

CTD anatomy: Analyzing chemical-induced phenotypes and exposures from an anatomical perspective, with implications for environmental health studies

CURRENT RESEARCH IN TOXICOLOGY, 2, 128–139.

author keywords: Anatomy; Chemical; Phenotype; Disease; Environmental health; Database
Sources: Web Of Science, ORCID
Added: January 3, 2022

2021 article

Development and Application of Multidimensional Lipid Libraries to Investigate Lipidomic Dysregulation Related to Smoke Inhalation Injury Severity

Kirkwood, K. I., Christopher, M. W., Burgess, J. L., Littau, S. R., Foster, K., Richey, K., … Baker, E. S. (2021, December 7). JOURNAL OF PROTEOME RESEARCH, Vol. 12.

By: K. Kirkwood n, M. Christopher n, J. Burgess*, S. Littau*, K. Foster*, K. Richey*, B. Pratt*, N. Shulman* ...

author keywords: lipidomics; ion mobility spectrometry; spectral libraries; data annotation; smoke inhalation
MeSH headings : Chromatography, Liquid; Humans; Ion Mobility Spectrometry; Lipidomics; Lipids; Smoke Inhalation Injury
Sources: Web Of Science, NC State University Libraries
Added: December 20, 2021

2021 article

Per- and polyfluoroalkyl substances (PFAS)-contaminants of emerging concern

Baker, E. S., & Knappe, D. R. U. (2021, December 2). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 12.

By: E. Baker n & D. Knappe*

MeSH headings : Anthropogenic Effects; Environmental Pollutants / analysis; Environmental Pollutants / pharmacokinetics; Fluorocarbons / analysis; Fluorocarbons / pharmacokinetics; Humans; Tissue Distribution; United States; United States Environmental Protection Agency
TL;DR: It was imperative to assemble this PFAS topical collection to be a critical resource as Published in the topical collection Perand Polyfluoroalkyl Substances (PFAS) – Contaminants of Emerging Concern with guest editors Erin Baker and Detlef Knappe. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 13, 2021

2021 journal article

Enzyme Complexes of Ptr4CL and PtrHCT Modulate Co-enzyme A Ligation of Hydroxycinnamic Acids for Monolignol Biosynthesis in Populus trichocarpa

FRONTIERS IN PLANT SCIENCE, 12.

By: C. Lin n, Y. Sun*, J. Song n, H. Chen n, R. Shi n, C. Yang n, J. Liu n, S. Tunlaya-Anukit n ...

author keywords: protein interaction; monolignol biosynthesis; wood formation; Populus trichocarpa; BiFC; metabolic flux
TL;DR: It is proposed that Ptr4CL/PtrHCT complexes modulate the metabolic flux of CoA ligation for monolignol biosynthesis during wood formation in P. trichocarpa. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: November 8, 2021

2021 journal article

Key Characteristics of Cardiovascular Toxicants

ENVIRONMENTAL HEALTH PERSPECTIVES, 129(9).

By: L. Lind, J. Araujo*, A. Barchowsky*, S. Belcher n, B. Berridge*, N. Chiamvimonvat*, W. Chiu*, V. Cogliano* ...

MeSH headings : Air Pollutants / analysis; Air Pollution / analysis; Carcinogens; Environmental Pollutants / toxicity; Hazardous Substances / toxicity; Particulate Matter / analysis
TL;DR: The KCs could be used to identify potential CV toxicants and to define a set of test methods to evaluate CV toxicity in a more comprehensive and standardized manner than current approaches. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: November 8, 2021

2021 article

Gestational Cd Exposure in the CD-1 Mouse Sex-Specifically Disrupts Essential Metal Ion Homeostasis

Jackson, T. W., Baars, O., & Belcher, S. M. (2021, November 7). (Vol. 11). Vol. 11.

TL;DR: It is demonstrated that Cd can preferentially cross the female placenta, accumulate in the liver, and cause lifelong dysregulation of metal ion concentrations associated with metabolic disruption. (via Semantic Scholar)
Source: ORCID
Added: November 8, 2021

2021 review

Critical review on PFOA, kidney cancer, and testicular cancer

[Review of ]. JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION, 71(10), 1265–1276.

By: E. Stevenson*, M. Kleinman*, X. Bai*, M. Barlaz n, M. Abraczinskas*, V. Guidry*, J. Watson*, J. Chow*

MeSH headings : Caprylates / toxicity; Fluorocarbons / toxicity; Humans; Kidney Neoplasms; Male; Neoplasms, Germ Cell and Embryonal; Testicular Neoplasms
TL;DR: Department of Meteorology and Measurement, Bay Area Air Quality Management District, San Francisco, CA, USA; Air Pollution Health Effects Laboratory, Department of Environmental and Occupational Health, University of California, Irvine, CA; Division of Hydrologic Sciences, Desert Research Institute, Las Vegas, NV, USA. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: November 1, 2021

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