Works Published in 2017

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Displaying works 501 - 520 of 748 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2017 journal article

Heat tolerance predicts the importance of species interaction effects as the climate changes

INTEGRATIVE AND COMPARATIVE BIOLOGY, 57(1), 112–120.

By: S. Diamond*, L. Chick*, C. Penick n, L. Nichols n, S. Cahan*, R. Dunn n, A. Ellison*, N. Sandersk, N. Gotelli*

MeSH headings : Animals; Ants / physiology; Climate Change; Ecosystem; Forests; Hot Temperature; North America; Species Specificity; Thermotolerance / physiology
TL;DR: Overall, mixed support is found for the importance of negative species interactions (competition), but it is found that the magnitude of these interaction effects was predictable based on the heat tolerance of the focal species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Genomic estimation of complex traits reveals ancient maize adaptation to temperate North America

SCIENCE, 357(6350), 512–515.

By: K. Swarts*, R. Gutaker*, B. Benz*, M. Blake*, R. Bukowski*, J. Holland n, M. Kruse-Peeples, N. Lepak* ...

Contributors: K. Swarts*, R. Gutaker*, B. Benz*, M. Blake*, R. Bukowski*, J. Holland n, M. Kruse-Peeples, N. Lepak* ...

MeSH headings : Acclimatization / genetics; Cold Temperature; Flowers / genetics; Flowers / physiology; Genome, Plant; Genomics; Multifactorial Inheritance; North America; Phenotype; Zea mays / genetics; Zea mays / physiology
TL;DR: Indirectly validated genomic models predicted that Turkey Pen maize was marginally adapted with respect to flowering, as well as short, tillering, and segregating for yellow kernel color, a characteristic of modern temperate maize. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Genetic Architecture of Natural Variation Underlying Adult Foraging Behavior That Is Essential for Survival of Drosophila melanogaster

GENOME BIOLOGY AND EVOLUTION, 9(5), 1357–1369.

By: Y. Lee*, Q. Yang*, W. Chi*, S. Turkson*, W. Du*, C. Kemkemer*, Z. Zeng n, M. Long*, X. Zhuang*

author keywords: genome-wide association study; foraging behavior; Drosophila melanogaster; inbreeding depression
TL;DR: It is found that adult foraging behavior has a strong genetic component and, unlike larval foragingbehavior, depends on multiple loci and shed light on the initial stage underlying the evolution of the behavior. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Gene Therapy in a Large Animal Model of PDE6A-Retinitis Pigmentosa

FRONTIERS IN NEUROSCIENCE, 11.

By: F. Mowat n, L. Occelli*, J. Bartoe*, K. Gervais*, A. Bruewer*, J. Querubin*, A. Dinculescu*, S. Boye*, W. Hauswirth*, S. Petersen-Jones*

author keywords: retinitis pigmentosa; Pde6 mutation; gene therapy; canine model; adeno-associated virus
TL;DR: This is the first description of successful gene augmentation for Pde6a retinitis pigmentosa in a large animal model and further studies will be necessary to optimize visual outcomes and minimize complications before translation to human studies. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Evaluating strategies for reversing CRISPR-Cas9 gene drives

Scientific Reports, 7(1).

By: M. Vella n, C. Gunning n, A. Lloyd n & F. Gould n

MeSH headings : CRISPR-Associated Protein 9 / metabolism; Clustered Regularly Interspaced Short Palindromic Repeats; Gene Drive Technology / methods; Genetics, Population / methods; Models, Statistical; Organisms, Genetically Modified / genetics; Time Factors
TL;DR: A discrete time model for population genetics of a drive and proposed genetic countermeasures is developed and predicts unexpected behavior including polymorphic equilibria and oscillatory dynamics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Escherichia coli O157:H7 Acid Sensitivity Correlates with Flocculation Phenotype during Nutrient Limitation

FRONTIERS IN MICROBIOLOGY, 8.

By: K. Kay n, F. Breidt n, P. Fratamico*, G. Baranzoni*, G. Kim*, A. Grunden n, D. Oh*

author keywords: STEC; acid resistance; nutrient limitation; curli; GcvB
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Dietary prebiotics and arachidonic acid alter intestinal phospholipid composition and time-dependently change fecal microbiome in formula-fed piglets

FASEB Journal, 31.

By: M. Thorpe, L. Xi, C. Maltecca, K. Walters, A. Smith, J. Odle, S. Jacobi

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

CpG and methylation-dependent DNA binding and dynamics of the methylcytosine binding domain 2 protein at the single-molecule level

NUCLEIC ACIDS RESEARCH, 45(15), 9164–9177.

By: H. Pan n, S. Bilinovich*, P. Kaur n, R. Riehn n, H. Wang n & D. Williams*

MeSH headings : 5-Methylcytosine / chemistry; 5-Methylcytosine / metabolism; Animals; Binding Sites; Chickens; Cloning, Molecular; CpG Islands; DNA / chemistry; DNA / metabolism; DNA Methylation; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Escherichia coli / genetics; Escherichia coli / metabolism; Fluorescence Polarization; Gene Expression; Humans; Magnetic Resonance Spectroscopy; Mi-2 Nucleosome Remodeling and Deacetylase Complex / metabolism; Mi-2 Nucleosome Remodeling and Deacetylase Complex / ultrastructure; Nucleic Acid Conformation; Nucleosomes / metabolism; Nucleosomes / ultrastructure; Protein Binding; Protein Isoforms / chemistry; Protein Isoforms / genetics; Protein Isoforms / metabolism; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Single Molecule Imaging
TL;DR: The results suggest that MBD2 targets NuRD to unmethylated or methylated CpG islands where its distinct dynamic binding modes help maintain open or closed chromatin, respectively. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Bioavailability of Carbohydrate Content in Natural and Transgenic Switchgrasses for the Extreme Thermophile Caldicellulosiruptor bescii

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 83(17).

By: J. Zurawski n, P. Khatibi n, H. Akinosho*, C. Straub n, S. Compton n, J. Conway n, L. Lee n, A. Ragauskas* ...

author keywords: Caldicellulosiruptor; switchgrass; lignocellulose deconstruction and conversion; extreme thermophiles; lignocellulose
MeSH headings : Biomass; Fermentation; Gram-Positive Bacteria / genetics; Gram-Positive Bacteria / metabolism; Hot Temperature; Lignin / chemistry; Lignin / metabolism; Panicum / chemistry; Panicum / genetics; Panicum / metabolism; Panicum / microbiology; Plants, Genetically Modified / chemistry; Plants, Genetically Modified / genetics; Plants, Genetically Modified / metabolism; Plants, Genetically Modified / microbiology; Polysaccharides / chemistry; Polysaccharides / metabolism
TL;DR: While C. bescii could significantly solubilize the transgenic switchgrass lines and natural variant tested here, additional or alternative strategies (physical, chemical, enzymatic, and/or genetic) are needed to eliminate recalcitrance. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Adrenal-derived stress hormones modulate ozone-induced lung injury and inflammation

TOXICOLOGY AND APPLIED PHARMACOLOGY, 329, 249–258.

By: A. Henriquez*, J. House n, D. Miller*, S. Snow*, A. Fisher*, H. Ren*, M. Schladweiler*, A. Ledbetter*, F. Wright n, U. Kodavanti*

author keywords: Ozone; Lung; Stress hormones; Adrenalectomy; RNAseq
MeSH headings : Adrenal Cortex / metabolism; Adrenal Cortex / surgery; Adrenal Medulla / metabolism; Adrenal Medulla / surgery; Adrenalectomy; Animals; Corticosterone / blood; Cytokines / metabolism; Disease Models, Animal; Epinephrine / blood; Gene Expression Regulation; Inflammation Mediators / metabolism; Lung / metabolism; Lung / pathology; Lung Injury / blood; Lung Injury / chemically induced; Lung Injury / genetics; Lung Injury / prevention & control; Male; Neutrophils / metabolism; Oxidative Stress; Ozone; Pneumonia / blood; Pneumonia / chemically induced; Pneumonia / genetics; Pneumonia / pathology; Pneumonia / prevention & control; RNA, Messenger / genetics; RNA, Messenger / metabolism; Rats, Inbred WKY; Signal Transduction; Stress, Physiological / genetics; Transcription, Genetic
TL;DR: It is demonstrated that ozone‐induced lung injury and neutrophilic inflammation require the presence of circulating epinephrine and corticosterone, which transcriptionally regulates signaling mechanisms involved in this response. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Acetylcholinesterase plays a non-neuronal, non-esterase role in organogenesis

DEVELOPMENT, 144(15), 2764–2770.

author keywords: Acetylcholinesterase; Morphogenesis; Gut; Intestine; Fibronectin; Xenopus laevis
MeSH headings : Acetylcholine / metabolism; Acetylcholinesterase / genetics; Acetylcholinesterase / metabolism; Animals; Cell Adhesion / physiology; Embryo, Nonmammalian / metabolism; Endoderm / cytology; Endoderm / metabolism; Fibronectins / genetics; Fibronectins / metabolism; Immunohistochemistry; Nervous System / embryology; Nervous System / metabolism; Organogenesis / genetics; Organogenesis / physiology; RNA, Messenger / genetics; Xenopus laevis / embryology; Xenopus laevis / genetics; Xenopus laevis / metabolism
TL;DR: A non-classical function of acetylcholinesterase in the polarization, rearrangement and adhesion of endoderm cells during Xenopus gut morphogenesis is identified and has wide-reaching implications for development and toxicology. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

A novel plant DNA extraction method using filter paper-based 96-well spin plate

Planta, 246(3), 579–584.

By: R. Shi n & D. Panthee n

author keywords: Filter paper; DNA extraction; Inexpensive; Safe; High throughput; Solanum lycopersicum; Ph-3 gene
MeSH headings : Centrifugation / instrumentation; Centrifugation / methods; DNA, Plant / isolation & purification; Electrophoresis / methods; Genetic Markers; Polymerase Chain Reaction; Reproducibility of Results
TL;DR: It was confirmed that filter paper is an efficient solid-phase DNA binding material and comparable to silicon-based glass fiber filters adopted in commercial DNA extraction kits, and that plant DNA extracted by this method can be readily used as template for PCR. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

VapC toxins drive cellular dormancy under uranium stress for the extreme thermoacidophile Metallosphaera prunae

ENVIRONMENTAL MICROBIOLOGY, 19(7), 2831–2842.

MeSH headings : Archaeal Proteins / genetics; Archaeal Proteins / metabolism; Bacterial Toxins / genetics; Bacterial Toxins / metabolism; Gene Expression Regulation, Bacterial / physiology; RNA Stability / physiology; Sulfolobaceae / genetics; Sulfolobaceae / growth & development; Sulfolobaceae / metabolism; Transcriptome; Uranium / metabolism
TL;DR: M. prunae utilizes VapC toxins for post-transcriptional regulation under uranium stress to enter a cellular dormant state, thereby providing an adaptive response to what would otherwise be a deleterious environmental perturbation. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 article

Transcriptomic Analysis in Strawberry Fruits Reveals Active Auxin Biosynthesis and Signaling in the Ripe Receptacle (vol 8, pg 889, 2017)

Estrada-Johnson, E., Csukasi, F., Pizarro, C. M., Vallarino, J. G., Kiryakova, Y., Vioque, A., … Valpuesta, V. (2017, July 24). FRONTIERS IN PLANT SCIENCE, Vol. 8.

By: E. Estrada-Johnson*, F. Csukasi*, C. Pizarro*, J. Vallarino*, Y. Kiryakova*, A. Vioque*, C. Merchante*, J. Brumos n ...

author keywords: auxin; fruit; strawberry; transcriptome regulation; ripening
TL;DR: This paper presents a meta-analyses of the determinants of infectious disease in eight operation theatres of the immune system and three of them are confirmed to be immune-to-inflammatory bowel diseases. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

The relationship between different measures of feed efficiency and feeding behavior traits in Duroc pigs

Journal of Animal Science, 95(8), 3370–3380.

By: D. Lu, S. Jiao*, F. Tiezzi, M. Knauer*, Y. Huang, K. Gray, maltecca

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: NC State University Libraries, NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Overexpression of a type-I isopentenyl pyrophosphate isomerase of Artemisia annua in the cytosol leads to high arteannuinB production and artemisinin increase

Plant Journal, 91(3), 466–479.

MeSH headings : Artemisia annua / enzymology; Artemisia annua / genetics; Artemisia annua / metabolism; Artemisinins / metabolism; Carbon-Carbon Double Bond Isomerases / genetics; Carbon-Carbon Double Bond Isomerases / metabolism; Cytosol / enzymology; Cytosol / metabolism; Hemiterpenes; Plant Proteins / genetics; Plant Proteins / metabolism; Plants, Genetically Modified / enzymology; Plants, Genetically Modified / genetics; Plants, Genetically Modified / metabolism
TL;DR: Evidence is provided that overexpression of AaIPPI1 in the cytosol can lead to metabolic alterations of terpenoid biosynthesis, and it is shown that transgenic plants have the potential to yield high production levels of arteannuin B as a new precursor source for artemisinin. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2017 journal article

Oral transmucosal detomidine gel in New Zealand white rabbits (Oryctolagus cuniculus)

Journal of the American Association for Laboratory Animal Science, 56(4), 436–442.

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Nest-site selection and nest survival of Bachman's Sparrows in two longleaf pine communities

CONDOR, 119(3), 361–374.

author keywords: Bachman's Sparrow; fire; landscape; longleaf pine; nest survival; nest-site selection; Peucaea aestivalis; physiographic region
TL;DR: Results indicate that creating and maintaining community-specific vegetation characteristics through the application of frequent prescribed fire should increase the amount of nesting cover for Bachman's Sparrows. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Macro-scale assessment of demographic and environmental variation within genetically derived evolutionary lineages of eastern hemlock (Tsuga canadensis), an imperiled conifer of the eastern United States

Biodiversity and Conservation, 26(9), 2223–2249.

author keywords: Genetic variation; Environmental variation; Intraspecific variation; Genetic zones; Evolutionary lineages; Climate change
TL;DR: Results show that future habitats under climate change will markedly decline for eastern hemlock, pointing to the need to focus conservation efforts on this ecologically and genetically important region. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2017 journal article

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling

Development, 144(16), 2925–2939.

By: Y. Chernyavskaya*, R. Mudbhary*, C. Zhang n, D. Tokarz*, V. Jacob*, S. Gopinath*, X. Sun*, S. Wang* ...

author keywords: Transposon; DNA methylation; Uhrf1; Interferon; Antiviral
MeSH headings : Animals; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases / genetics; DNA (Cytosine-5-)-Methyltransferases / metabolism; DNA Methylation / genetics; DNA Methylation / physiology; Retroelements / genetics; Signal Transduction / genetics; Signal Transduction / physiology; Trans-Activators / genetics; Trans-Activators / metabolism; Zebrafish / embryology; Zebrafish / metabolism; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
TL;DR: Activation of transposons in cells with global DNA hypomethylation mimics a viral infection by activating cytoplasmic DNA viral sensors suggests that antiviral pathways serve as surveillance of cells that have derepressed intragenomic parasites due to DNA hypometrichylations. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

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