Works Published in 2017

search works

Displaying works 541 - 560 of 748 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2017 personal communication

Janus kinase inhibitors display broad anti-itch properties: A possible link through the TRPV1 receptor

Fukuyama, T., Ganchingco, J. R., Mishra, S. K., Olivry, T., Rzagalinski, I., Volmer, D. A., & Baeumer, W. (2017, July).

By: T. Fukuyama n, J. Ganchingco n, S. Mishra n, T. Olivry n, I. Rzagalinski*, D. Volmer*, W. Baeumer

MeSH headings : Animals; Antipruritics / chemistry; Antipruritics / pharmacology; Dopaminergic Neurons / drug effects; Dopaminergic Neurons / metabolism; Female; Humans; Janus Kinase Inhibitors / chemistry; Janus Kinase Inhibitors / pharmacology; Mice; Models, Molecular; Molecular Conformation; Molecular Imaging / methods; Protein Binding; Sensory Receptor Cells / drug effects; Sensory Receptor Cells / metabolism; Structure-Activity Relationship; TRPV Cation Channels / antagonists & inhibitors; TRPV Cation Channels / chemistry; TRPV Cation Channels / metabolism
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 article

Introduction to the special issue highlighting Anaerobe 2016

Cox, L. M., Theriot, C. M., & Fichorova, R. N. (2017, June). ANAEROBE, Vol. 45, pp. 1–2.

MeSH headings : Bacteria, Anaerobic / pathogenicity; Bacterial Infections / diagnosis; Bacterial Infections / epidemiology; Bacterial Infections / therapy; Biomedical Research / trends; Global Health; Microbiology / trends; Tennessee
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Intracoronary allogeneic cardiosphere-derived stem cells are safe for use in dogs with dilated cardiomyopathy

Journal of Cellular and Molecular Medicine, 21(8), 1503–1512.

By: M. Hensley n, J. Tang n, K. Woodruff n, T. DeFrancesco n, S. Tou n, C. Williams n, M. Breen n, K. Meurs n ...

author keywords: cardiosphere-derived cells; dogs; dilated cardiomyopathy; stem cell therapy; allogeneic
MeSH headings : Animals; Biomarkers / metabolism; Cardiomyopathy, Dilated / diagnostic imaging; Cardiomyopathy, Dilated / immunology; Cardiomyopathy, Dilated / pathology; Cardiomyopathy, Dilated / therapy; Coronary Vessels / cytology; Coronary Vessels / immunology; Dogs; Echocardiography; Endoglin / genetics; Endoglin / immunology; Female; Gene Expression; Humans; Male; Myocardium / immunology; Myocardium / pathology; Proto-Oncogene Proteins c-kit / genetics; Proto-Oncogene Proteins c-kit / immunology; Spheroids, Cellular / cytology; Spheroids, Cellular / immunology; Spheroids, Cellular / transplantation; Stem Cell Transplantation; Stem Cells / cytology; Stem Cells / immunology; Thy-1 Antigens / genetics; Thy-1 Antigens / immunology; Transplantation, Homologous
TL;DR: The safety and efficacy of allogeneic CDC in a large animal (canine) model of spontaneous DCM and Histology on dog hearts revealed no sign of immune rejection from the transplanted cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2017 journal article

Integrated immunohistochemical and DNA copy number profiling analysis provides insight into the molecular pathogenesis of canine follicular lymphoma

VETERINARY AND COMPARATIVE ONCOLOGY, 15(3), 852–867.

By: R. Thomas n, Z. Demeter*, K. Kennedy n, L. Borst n, K. Singh*, V. Valli, K. Le Boedec*, M. Breen n

author keywords: BCL2; canine; comparative genomic hybridization; fluorescence in situ hybridization; follicular lymphoma; immunohistochemistry
MeSH headings : Animals; DNA Copy Number Variations / genetics; DNA Fingerprinting / veterinary; Dog Diseases / etiology; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Genome-Wide Association Study / veterinary; Lymphoma, Follicular / etiology; Lymphoma, Follicular / genetics; Lymphoma, Follicular / pathology; Lymphoma, Follicular / veterinary; Male; Risk Factors
TL;DR: Parallel exploration of canine and human cases may reveal alternative tumour-initiating mechanisms other than BCL2 disruption, yielding a more complete definition of the molecular pathogenesis of FL. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 article

Inhibition of spore germination, growth, and toxin activity of clinically relevant C-difficile strains by gut microbiota derived secondary bile acids

Thanissery, R., Winston, J. A., & Theriot, C. M. (2017, June). ANAEROBE, Vol. 45, pp. 86–100.

By: R. Thanissery n, J. Winston n & C. Theriot n

author keywords: C. difficile; Bile acids; Gut microbiota; Metabolome; Germination; Growth; Toxin
MeSH headings : Animals; Anti-Bacterial Agents / metabolism; Antibiosis; Bacterial Toxins / metabolism; Bile Acids and Salts / metabolism; Clostridioides difficile / drug effects; Clostridioides difficile / growth & development; Gastrointestinal Microbiome; Gastrointestinal Tract / microbiology; Humans; Mice; Spores, Bacterial / drug effects; Spores, Bacterial / growth & development
TL;DR: It is shown how clinically relevant C. difficile strains can have different responses when exposed to SBAs present in the gastrointestinal tract, and how these responses vary across all strains and ribotypes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Identification of a Campylobacter coli methyltransferase targeting adenines at GATC sites

FEMS Microbiology Letters, 364(7).

MeSH headings : Adenine / metabolism; Animals; Campylobacter coli / enzymology; Campylobacter coli / genetics; Cattle; DNA Methylation; Genome, Bacterial; Humans; Methyltransferases / genetics; Methyltransferases / isolation & purification; Methyltransferases / metabolism; Nucleotide Motifs; Open Reading Frames; Sequence Analysis / methods
TL;DR: To determine whether ORF0059 mediated MboI resistance and hence encoded a putative N6‐adenine DNA methyltransferase, the gene was cloned immediately upstream of a chloramphenicol resistance cassette (cat) and a PCR fragment harboring ORF 0059‐cat was transformed into C. coli 11601, suggesting a direct role of this gene in methylation of adenines at GATC sites. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Hybrid modeling and prediction of dynamical systems

PLOS Computational Biology, 13(7), e1005655.

By: F. Hamilton n, A. Lloyd n & K. Flores n

Ed(s): J. Saucerman

MeSH headings : Models, Biological; Models, Statistical; Neurons; Statistics, Nonparametric; Systems Biology
TL;DR: A hybrid approach to modeling and prediction which merges recent advancements in nonparametric analysis with standard parametric methods is considered, finding that this hybrid approach allows for more robust parameter estimation and improved short-term prediction in situations where there is a large uncertainty in model parameters. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Germline transformation of the western corn rootworm, Diabrotica virgifera virgifera

Insect Molecular Biology, 26(4), 440–452.

author keywords: Minos; piggyBac; small-scale rearing; embryonic microinjection
MeSH headings : Animals; Coleoptera / genetics; Female; Gene Transfer Techniques; Luminescent Proteins; Male; Transposases
TL;DR: Establishing transgenic technologies for this beetle is the first step towards bringing a wide range of transformation‐based tools to bear on understanding WCR biology. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Genetic Architecture and Molecular Networks Underlying Leaf Thickness in Desert-Adapted Tomato Solanum pennellii

PLANT PHYSIOLOGY, 175(1), 376–391.

By: V. Coneva*, M. Frank*, M. Balaguer n, M. Li*, R. Sozzani n & D. Chitwood*

MeSH headings : Adaptation, Physiological / genetics; Bayes Theorem; Desert Climate; Gene Regulatory Networks; Organ Specificity; Phenotype; Plant Leaves / anatomy & histology; Plant Leaves / genetics; Plant Leaves / growth & development; Plant Leaves / physiology; Quantitative Trait Loci / genetics; Sequence Analysis, RNA; Solanum / anatomy & histology; Solanum / genetics; Solanum / growth & development; Solanum / physiology
TL;DR: A custom-built confocal profilometer was used to directly measure leaf thickness in a set of introgression lines (ILs) derived from the desert tomato Solanum pennellii and identified quantitative trait loci to establish a framework of genetic, anatomical, and molecular mechanisms that pattern leaf thicknessIn desert-adapted tomato. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Foraging strategy predicts foraging economy in a facultative secondary nectar robber

Oikos, 126(9), 1250–1257.

TL;DR: Foraging strategy was a major predictor of foraging efficiency, with legitimate foraging being significantly more efficient than secondary robbing, and the need for deeper investigations into why bees adopt secondary robbing as a foraging strategy, specifically, the environmental contexts that promote the behavior. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018

2017 journal article

Experimental winter warming modifies thermal performance and primes acorn ants for warm weather

Journal of Insect Physiology, 100, 77–81.

Contributors: H. MacLean*, C. Penick n, R. Dunn n & S. Diamond*

author keywords: Climate change; Experimental climate warming; Running speed; Ants; Phenotypic plasticity
MeSH headings : Animals; Ants / physiology; Climate Change; Hot Temperature; Motor Activity; Random Allocation; Seasons; Weather
TL;DR: Evidence that overwintering temperatures can substantially influence organismal performance is provided, and it is suggested that organismal responses to environmental changes in temperature cannot be ignored when forecasting organismal behaviours. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Evolutionary divergence of the vertebrate TNFAIP8 gene family: Applying the spotted gar orthology bridge to understand ohnolog loss in teleosts

PLOS ONE, 12(6), e0179517.

By: C. Sullivan*, C. Lage*, J. Yoder n, J. Postlethwait* & C. Kim*

Ed(s): P. Boudinot

TL;DR: It is determined that teleost orthologs to human TNFAIP8 genes were likely lost in a genome inversion event after their divergence from their common ancestor with spotted gar, demonstrating the value of this enhanced approach to gene history analysis and support the development of teleost models to study complex questions related to an array of biomedical issues. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Context-dependent medicinal effects of anabasine and infection-dependent toxicity in bumble bees

PLOS ONE, 12(8), e0183729.

By: E. Palmer-Young*, A. Hogeboom*, A. Kaye*, D. Donnelly*, J. Andicoechea*, S. Connon n, I. Weston*, K. Skyrm*, R. Irwin n, L. Adler*

Ed(s): J. Hull

MeSH headings : Anabasine / toxicity; Animals; Bees / drug effects; Bees / parasitology; Host-Parasite Interactions / drug effects; Infections / drug therapy
TL;DR: Variation in the effect of anabasine on infection suggests potential modulation of tritrophic interactions by both host genotype and environmental variables, and suggests that the medicinal effects and toxicity of an abasine may be context dependent. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018

2017 journal article

Cheminformatics modeling of amine solutions for assessing their CO2 absorption properties

Molecular Informatics, 36(7).

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Characterizing the Chemical Space of ERK2 Kinase Inhibitors Using Descriptors Computed from Molecular Dynamics Trajectories

JOURNAL OF CHEMICAL INFORMATION AND MODELING, 57(6), 1286–1299.

By: J. Ash n & D. Fourches n

MeSH headings : Ligands; Mitogen-Activated Protein Kinase 1 / antagonists & inhibitors; Mitogen-Activated Protein Kinase 1 / chemistry; Mitogen-Activated Protein Kinase 1 / metabolism; Molecular Dynamics Simulation; Protein Conformation; Protein Kinase Inhibitors / chemistry; Protein Kinase Inhibitors / metabolism; Protein Kinase Inhibitors / pharmacology; Quantitative Structure-Activity Relationship; Solvents / chemistry; Temperature
TL;DR: This study represents the largest attempt to utilize MD-extracted chemical descriptors to characterize and model a series of bioactive molecules and showed that MD descriptors had little correlation with conventionally used 2D/3D descriptors, and were able to distinguish the most active ERK2 inhibitors from the moderate/weak actives and inactives. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Canine acute leukaemia: 50 cases (1989-2014)

VETERINARY AND COMPARATIVE ONCOLOGY, 15(3), 1101–1114.

By: A. Bennett n, L. Williams n, M. Ferguson n, M. Hauck n, S. Suter n, C. Lanier n, P. Hess n

author keywords: acute leukaemia; canine; chemotherapy; CHOP; immunophenotype
MeSH headings : Acute Disease; Animals; Antineoplastic Agents / adverse effects; Antineoplastic Agents / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / mortality; Dogs; Leukemia / drug therapy; Leukemia / mortality; Leukemia / veterinary; Retrospective Studies; Survival Analysis; Treatment Outcome
TL;DR: Most dogs developed chemoresistance within weeks of initiating treatment, and consequently, survival times for AL remain disappointingly short. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Auxin minimum triggers the developmental switch from cell division to cell differentiation in the Arabidopsis root

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(36), E7641–E7649.

By: R. Di Mambro, M. De Ruvo*, E. Pacifici, E. Salvi, R. Sozzani n, P. Benfey*, W. Busch*, O. Novak* ...

author keywords: plant hormones; cell differentiation; root meristem; computational modeling
MeSH headings : Arabidopsis / metabolism; Arabidopsis / physiology; Arabidopsis Proteins / metabolism; Biological Transport / physiology; Cell Differentiation / physiology; Cell Division / physiology; Cytokinins / metabolism; Gene Expression Regulation, Plant / physiology; Indoleacetic Acids / metabolism; Meristem / metabolism; Meristem / physiology; Plant Growth Regulators / metabolism; Plant Roots / metabolism; Plant Roots / physiology; Signal Transduction / physiology
TL;DR: Computational modeling and molecular genetics show that boundary formation is dependent on cytokinin’s control on auxin polar transport and degradation, and the regulation of both processes shapes the auxin profile in a well-defined auxin minimum. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Association of breed and histopathological grade in canine mast cell tumours

VETERINARY AND COMPARATIVE ONCOLOGY, 15(3), 829–839.

By: H. Mochizuki n, A. Motsinger-Reif n, C. Bettini, S. Moroff & M. Breen n

author keywords: Boxer; dog; epidemiology; genetics; MCT; Pug
MeSH headings : Age Factors; Animals; Dog Diseases / etiology; Dog Diseases / pathology; Dogs; Female; Male; Mastocytosis, Cutaneous / etiology; Mastocytosis, Cutaneous / pathology; Mastocytosis, Cutaneous / veterinary; Retrospective Studies; Risk Factors; Sex Factors; Skin Neoplasms / etiology; Skin Neoplasms / pathology; Skin Neoplasms / veterinary; Species Specificity
TL;DR: The data indicate that the proportion of high-grade tumours increases with advancing age, and that male and intact dogs have increased odds of developing high- grade tumours, and a genetic association for the development ofhigh-grade MCTs is suggested. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Arrhythmogenic Right Ventricular Cardiomyopathy in the Boxer Dog: An Update

VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE, 47(5), 1103-+.

By: K. Meurs n

author keywords: Boxer; ARVC; Cardiomyopathy; Arrhythmia
MeSH headings : Animals; Arrhythmogenic Right Ventricular Dysplasia / genetics; Arrhythmogenic Right Ventricular Dysplasia / veterinary; Dog Diseases / genetics; Dogs; Mutation; Pedigree; Prognosis
TL;DR: Arrhythmogenic right ventricular cardiomyopathy is an inheritable form of myocardial disease characterized most commonly by ventricular tachycardias, syncope, and sometimes systolic dysfunction and heart failure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

An improved and explicit surrogate variable analysis procedure by coefficient adjustment

BIOMETRIKA, 104(2), 303–316.

author keywords: Batch effect; High-dimensional data; Principal component analysis; Surrogate variable analysis
TL;DR: This paper proposes an improved surrogate variable analysis, using all measured features, that has anatural connection with restricted least squares, which allows for study of its theoretical properties and shows that the method is competitive with state‐of‐the‐art methods. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.