Works Published in 2021

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Displaying works 41 - 60 of 770 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2021 journal article

A PtrLBD39-mediated transcriptional network regulates tension wood formation in <i>Populus trichocarpa</i>.

Plant Communications, 1.

MeSH headings : Biomechanical Phenomena; Gene Expression Regulation, Plant / physiology; Gene Regulatory Networks / physiology; Genes, Plant / genetics; Genes, Plant / physiology; Laser Capture Microdissection; Populus / genetics; Populus / physiology; Wood / genetics; Wood / physiology; Xylem
TL;DR: This work suggests that P trLBD39 and PtrLBD22 specifically control TW formation by mediating a TW-specific TRN in Populus by directly regulating 26 novel TW-responsive transcription factor genes. (via Semantic Scholar)
Source: ORCID
Added: August 9, 2023

2021 article

ZFP36L1 regulates <i>Fgf21</i> mRNA turnover and modulates alcoholic hepatic steatosis and inflammation in mice

Bathula, C. S., Chen, J., Blackshear, P. J., Saini, Y., & Patial, S. (2021, May).

TL;DR: The results demonstrate that ZFP36L1 inactivation protects against alcohol-induced hepatic steatosis and liver injury, possibly by stabilizing Fgf21 mRNA and suggest that the modulation of ZFP 36L1 may be beneficial in the prevention or treatment of human alcoholic liver disease. (via Semantic Scholar)
Source: ORCID
Added: August 2, 2023

2021 journal article

ZFP36L1 Regulates Fgf21 mRNA Turnover and Modulates Alcoholic Hepatic Steatosis and Inflammation in Mice.

The American Journal of Pathology, 2.

MeSH headings : 3' Untranslated Regions; Animals; Butyrate Response Factor 1 / genetics; Butyrate Response Factor 1 / metabolism; Fatty Liver, Alcoholic / genetics; Fatty Liver, Alcoholic / metabolism; Fatty Liver, Alcoholic / pathology; Fibroblast Growth Factors / genetics; Fibroblast Growth Factors / metabolism; Inflammation / genetics; Inflammation / metabolism; Inflammation / pathology; Liver / metabolism; Liver / pathology; Mice; Mice, Knockout; Mutation; RNA Stability
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: August 2, 2023

2021 journal article

Vesicular and extravesicular protein analyses from the airspaces of ozone-exposed mice revealed signatures associated with mucoinflammatory lung disease.

Scientific Reports, 12.

MeSH headings : Animals; Bronchoalveolar Lavage Fluid / chemistry; Cytokines / analysis; Female; Inflammation Mediators / analysis; Male; Mice; Mice, Inbred C57BL; Ozone / adverse effects; Pneumonia / diagnosis; Proteins / analysis
TL;DR: Exosomal, secretory, and cell-specific proteins and biological pathways following repetitive exposure of mice to ozone are identified and significantly enhanced intracellular localization of mucoinflammatory proteins including MUC5B and FIZZ1 in ozone-exposed mice is revealed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: August 2, 2023

2021 journal article

Postnatal Ozone Exposure Disrupts Alveolar Development, Exaggerates Mucoinflammatory Responses, and Suppresses Bacterial Clearance in Developing <i>Scnn1b</i>-Tg<sup>+</sup> Mice Lungs.

Journal of Immunology (Baltimore, Md. : 1950), 8.

By: I. Choudhary*, T. Vo*, K. Paudel*, R. Yadav*, Y. Mao*, S. Patial*, Y. Saini*

MeSH headings : Animals; Bacteria / immunology; Cystic Fibrosis / immunology; Disease Models, Animal; Epithelial Sodium Channels / immunology; Inflammation / immunology; Lung / immunology; Macrophages / immunology; Mice; Mice, Transgenic; Mucus / immunology; Ozone / adverse effects; Postnatal Care
TL;DR: Ozone exposure results in alveolar space remodeling during active phases of lung development and markedly exaggerates the mucoinflammatory outcomes of pediatric-onset lung disease, including bacterial infections, granulocytic inflammation, mucus obstruction, and alveolars space enlargement. (via Semantic Scholar)
Source: ORCID
Added: August 2, 2023

2021 journal article

Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs.

Scientific Reports, 7.

By: S. Patial*, B. Lewis*, T. Vo*, I. Choudhary*, K. Paudel*, Y. Mao*, D. Singamsetty*, F. Brombacher*, Y. Saini*

MeSH headings : Alleles; Animals; Bronchoalveolar Lavage Fluid; Eosinophils / metabolism; Immunity, Innate; Interleukin-13 / metabolism; Interleukin-33 / metabolism; Ligands; Lung / metabolism; Lymphocytes / cytology; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myeloid Cells / metabolism; Pulmonary Eosinophilia; Receptors, Cell Surface / metabolism
TL;DR: It is established that myeloid-IL4Rα is an indispensable component of the IL-33-ILCsIL-13-IL 4Rα axis of eosinophil recruitment. (via Semantic Scholar)
Source: ORCID
Added: August 2, 2023

2021 article

Identifying C. elegans Lifespan Mutants by Screening for Early-Onset Protein Aggregation

Midkiff, D. F., & San-Miguel, A. (2021, December 16).

By: D. Midkiff n & A. San-Miguel n

Source: ORCID
Added: May 31, 2023

2021 article

Endogenous DAF-16 Spatiotemporal Activity Quantitatively Predicts Lifespan Extension Induced by Dietary Restriction

Huayta, J., & San-Miguel, A. (2021, December 21).

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: May 31, 2023

2021 journal article

Antagonistic effects of chemical mixtures on the oxidative stress response are silenced by heat stress and reversed under dietary restriction

Exposome, 1(1).

Source: ORCID
Added: May 31, 2023

2021 article

Antagonistic effects of chemical mixtures on the oxidative stress response are silenced by heat stress and reversed under dietary restriction

Arulalan, K. S., Huayta, J., Stallrich, J. W., & San-Miguel, A. (2021, March 19).

TL;DR: It is indicated that mixtures drive responses differently than individual components, and that altering environmental conditions, such as increased heat and reduced food availability, result in dramatically different oxidative stress responses mounted by C. elegans. (via Semantic Scholar)
Source: ORCID
Added: May 31, 2023

2021 chapter

Microfluidic devices for imaging and manipulation of C. elegans

In Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms (pp. 295–321).

Source: ORCID
Added: May 31, 2023

2021 chapter

5 Risk screening tools for engineered nanomaterials

In Ethics in Nanotechnology (pp. 89–108).

By: K. Grieger*, P. Isigonis, R. Franken, H. Wigger, N. Bossa, G. Janer, T. Rycroft, A. Kennedy, S. Hansen

Sources: Crossref, NC State University Libraries
Added: May 22, 2023

2021 article

Wastewater-Based Epidemiology and Whole-Genome Sequencing for Community-Level Surveillance of SARS-CoV-2 in Selected Urban Communities of Davao City, Philippines: A Pilot Study

Otero, M. C. B., Murao, L. A. E., Limen, M. A. G., Gaite, P. L. A., Bacus, M. G., Acaso, J. T., … Mundo, D. M. N. D. (2021, September 3).

By: M. Otero*, L. Murao*, M. Limen*, P. Gaite*, M. Bacus*, J. Acaso*, K. Corazo*, I. Knot* ...

TL;DR: WBE and WGS as approaches for COVID-19 surveillance in low-resource and low-sanitation communities in Davao City, Philippines were piloted and genomic surveillance in wastewater confirmed the presence of previously reported mutations while identifying mutations not yet registered in clinical surveillance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: April 19, 2023

2021 journal article

Images carried before the fire: The power, promise, and responsibility of latent phenotyping in plants

The Plant Phenome Journal, 4(1).

By: M. Feldmann*, J. Gage*, S. Turner-Hissong & J. Ubbens*

Contributors: J. Gage*

TL;DR: The differences between, and challenges of, both traditional and latent phenotyping are discussed. (via Semantic Scholar)
Source: ORCID
Added: April 18, 2023

2021 journal article

Rapid assessment of T-cell receptor specificity of the immune repertoire

Nature Computational Science, 1(5), 362–373.

TL;DR: RACER applies supervised machine learning to efficiently and accurately resolve strong TCR–peptide binding pairs from weak ones and accurately estimates recognition rates for tumor-associated neoantigens and foreign peptides, thus demonstrating its utility in helping address the computational challenge of reliably identifying properties of tumor antigen-specific T-cells at the level of an individual patient’s immune repertoire. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: April 7, 2023

2021 article

Isolating and growing fibroblast cells from threespine stickleback (Gasterosteus aculeatus) v2

Le, G. Q., Steinel, N., Fuess, L., Rodgers, M., & Bolnick, D. (2021, December 13). (Vol. 12). Vol. 12.

TL;DR: This protocol goes through the process of isolating and growing fibroblast cells from threespine stickleback and shows the importance of knowing the carrier and removal status of canine coronavirus. (via Semantic Scholar)
Source: ORCID
Added: April 6, 2023

2021 journal article

The impact of salinity and dissolved oxygen regimes on transcriptomic immune responses to oil in early life stage Fundulus grandis

Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics, 37.

By: M. Rodgers*, J. Serafin*, M. Sepúlveda* & R. Griffitt*

Contributors: M. Rodgers*, J. Serafin*, M. Sepúlveda* & R. Griffitt*

MeSH headings : Animals; Fundulidae / genetics; Fundulidae / growth & development; Fundulidae / immunology; Gene Expression Regulation, Developmental / drug effects; Immunity / drug effects; Larva / drug effects; Larva / genetics; Larva / growth & development; Larva / immunology; Oxygen / immunology; Oxygen / metabolism; Petroleum Pollution / adverse effects; Salinity; Transcriptome / drug effects; Water Pollutants, Chemical / adverse effects
TL;DR: Examination of transcriptional patterns of immune genes and pathways in Fundulus grandis larvae to various oil, salinity, and DO regimes suggests that oil under certain environmental conditions has the potential to further modulate immune-related genes, pathways, and responses in fish. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: April 6, 2023

2021 journal article

Isolating and growing fibroblast cells from threespine stickleback (Gasterosteus aculeatus)

Protocols.io.

By: M. Rodgers*, L. Fuess & D. Bolnick

Source: ORCID
Added: April 6, 2023

2021 journal article

Characterizing transcriptomic responses of southern flounder (Paralichthys lethostigma) chronically exposed to Deepwater Horizon oiled sediments

Aquatic Toxicology, 230.

By: M. Rodgers*, T. Sherwood*, A. Tarnecki*, R. Griffitt* & D. Wetzel*

Contributors: M. Rodgers*, T. Sherwood*, A. Tarnecki*, R. Griffitt* & D. Wetzel*

MeSH headings : Animals; Computational Biology; Flounder / genetics; Geologic Sediments / chemistry; Gills / chemistry; Gills / drug effects; Gulf of Mexico; Liver / chemistry; Liver / drug effects; Petroleum / toxicity; Petroleum Pollution / adverse effects; Transcriptome / drug effects; Water Pollutants, Chemical / toxicity
TL;DR: It is demonstrated that liver and gill tissues from southern flounder were differentially altered by Deepwater Horizon oiled sediment exposure and that a 30-day recovery period after exposure substantially shifted gene expression and canonical pathway profiles. (via Semantic Scholar)
Source: ORCID
Added: April 6, 2023

2021 journal article

Galaxolide and tonalide modulate neuroendocrine activity in marine species from two taxonomic groups

Environmental Research.

By: F. Ehiguese*, M. Rodgers*, C. Araújo*, R. Griffitt* & M. Martin-Diaz*

MeSH headings : Adult; Benzopyrans; Ecosystem; Humans; Tetrahydronaphthalenes / analysis; Tetrahydronaphthalenes / toxicity; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / toxicity
TL;DR: The results of this study demonstrate that HHCB and AHTN might pose neurotoxic and endocrine disrupting effects in coastal ecosystems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: April 6, 2023

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