Works Published in 2008
Displaying works 81 - 100 of 473 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2008 journal article
Roles of pgaABCD Genes in Synthesis, Modification, and Export of the Escherichia coli Biofilm Adhesin Poly-β-1,6-N-Acetyl-d-Glucosamine
Journal of Bacteriology, 190(10), 3670–3680.
MeSH headings : Adhesins, Escherichia coli / biosynthesis; Adhesins, Escherichia coli / metabolism; Amidohydrolases / physiology; Biofilms; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli / physiology; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Escherichia coli Proteins / physiology; Gene Expression Regulation, Bacterial; Microscopy, Immunoelectron; Operon / genetics; Polysaccharides / biosynthesis; beta-N-Acetylhexosaminidases / physiology
TL;DR:
Covalent modification of beta-1,6-GlcNAc by N-deacetylation serves distinct biological functions in gram-negative and gram-positive species, dictated by cell envelope differences.
(via Semantic Scholar)
jb.asm.org (publisher PDF)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 30, 2020
2008 journal article
Environmental influences on biofilm development.
Current Topics in Microbiology and Immunology.
MeSH headings : Bacterial Adhesion / physiology; Bacterial Physiological Phenomena; Biofilms / growth & development; Chemotaxis / physiology; Ecosystem; Humans; Polysaccharides, Bacterial / physiology; Surface Properties
TL;DR:
This chapter will present examples of how environmental conditions affect biofilm development, most of which come from studies of species that have mammalian hosts.
(via Semantic Scholar)
Source: ORCID
Added: December 30, 2020
2008 journal article
Genomic targeting and mapping of tiller inhibition gene (tin3) of wheat using ESTs and synteny with rice
Functional & Integrative Genomics, 8(1), 33–42.
author keywords: comparative genomics; genome mapping; wheat; tillering; synteny; Triticum monococcum
MeSH headings : Chromosomes, Artificial, Bacterial / genetics; Expressed Sequence Tags; Genes, Plant / genetics; Genetic Markers; Genomics; Oryza / genetics; Physical Chromosome Mapping / methods; Polymorphism, Restriction Fragment Length; Sequence Tagged Sites; Synteny / genetics; Triticum / genetics
Sources: Crossref, NC State University Libraries
Added: December 28, 2020
2008 journal article
Synthesis of Hydroxylated Bicyclic Amino Acids from l-Tyrosine: Octahydro-1 H-indole Carboxylates
The Journal of Organic Chemistry, 73(19), 7807–7810.
MeSH headings : Amino Acids / chemical synthesis; Amino Acids / chemistry; Bridged Bicyclo Compounds / chemical synthesis; Carboxylic Acids / chemistry; Hydroxylation; Indoles / chemistry; Stereoisomerism; Tyrosine / chemistry
TL;DR:
A stereoselective approach to polyhydroxylated L-Choi derivatives has been developed and the oxidative cyclization of L-tyrosine was optimized to avoid partial racemization and to allow a more efficient scale-up.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 22, 2020
2008 journal article
A high-throughput fluorescence-based glycosyltransferase screen and its application in directed evolution
Nature Protocols, 3(3), 357–362.
MeSH headings : Bacterial Proteins / genetics; Biomedical Engineering / methods; Directed Molecular Evolution / methods; Escherichia coli / genetics; Fluorescence; Gene Library; Glucosyltransferases / genetics; Glycosylation; Glycosyltransferases / analysis; Glycosyltransferases / metabolism; Mutagenesis / genetics; Mutation / genetics; Streptomyces antibioticus / enzymology
TL;DR:
This protocol details the application of a high-throughput fluorescence-based screen, in conjunction with error-prone PCR/saturation mutagenesis, for altering the proficiency and/or promiscuity of a secondary metabolite glycosyltransferase (GT) via directed evolution.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 22, 2020
2008 journal article
Optimizing Glycosyltransferase Specificity via “Hot Spot” Saturation Mutagenesis Presents a Catalyst for Novobiocin Glycorandomization
Chemistry & Biology, 15(4), 393–401.
MeSH headings : Amino Acid Substitution; Amino Acids; Binding Sites; Catalysis; Directed Molecular Evolution; Fluorescence; Glycosylation; Glycosyltransferases / chemistry; Glycosyltransferases / genetics; Glycosyltransferases / metabolism; Kinetics; Mutagenesis, Site-Directed / methods; Novobiocin / metabolism; Oleandomycin / metabolism; Substrate Specificity
TL;DR:
A comprehensive two-phase "hot spot" saturation mutagenesis strategy for the rapid evolution of glycosyltransferase (GT) specificity for nonnatural acceptors is described, which rapidly led to improvements in the desired catalytic activity of several hundred-fold.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 22, 2020
2008 journal article
The impact of enzyme engineering upon natural product glycodiversification
Current Opinion in Chemical Biology, 12(5), 556–564.
MeSH headings : Biological Products / chemical synthesis; Biological Products / chemistry; Biological Products / metabolism; Directed Molecular Evolution; Glycosylation; Glycosyltransferases / chemistry; Glycosyltransferases / metabolism; Humans; Protein Engineering / methods; Substrate Specificity
TL;DR:
This review highlights recent progress in the engineering/evolution of enzymes relevant to natural product glycodiversification with a particular focus upon GTs.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 22, 2020
2008 journal article
Probing the Aglycon Promiscuity of an Engineered Glycosyltransferase
Angewandte Chemie International Edition, 47(46), 8889–8892.
author keywords: carbohydrates; enzymes; glycosides; glycosylation; natural products
MeSH headings : Carbohydrate Metabolism; Carbohydrates / chemistry; Catalysis; Glycosyltransferases / metabolism; Molecular Structure; Protein Engineering; Streptomyces antibioticus / enzymology
TL;DR:
This study highlights the ability of OleD variants to glucosylate a total of 71 diverse acceptors, catalyze iterative glycosylation with numerous substrates, and establishes OleD as the first multifunctional GT capable of generating O-, S- and N-glycosides.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 22, 2020
2008 book
Theoretical and Biological Foundations of Plant Breeding
In Plant Breeding: The Arnel R. Hallauer International Symposium (pp. 127–140).
Contributors: J. Holland n
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: December 8, 2020
2008 journal article
Genetic design and statistical power of nested association mapping in maize
Genetics, 178(1), 539–551.
Contributors: J. Yu *, J. Holland n , M. McMullen* & E. Buckler *
MeSH headings : Chromosome Mapping; Genetic Markers; Genome, Plant / genetics; Genotype; Inbreeding; Models, Genetic; Polymorphism, Genetic; Quantitative Trait Loci / genetics; Zea mays / genetics
TL;DR:
The genetic and statistical properties of the nested association mapping (NAM) design currently being implemented in maize is investigated to dissect the genetic basis of complex quantitative traits.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: ORCID
Added: December 8, 2020
2008 journal article
Climatic adaptation and ecological descriptors of 42 Mexican maize races
Crop Science, 48(4), 1502–1512.
Contributors: J. Ruiz Corral *, N. Durán Puga, J. Sánchez González, J. Ron Parra, D. González Eguiarte, J. Holland n , G. Medina García *
TL;DR:
These climatic ranges of maize surpass those from its closest relative, teosinte (Z. mays ssp. parviglumis Iltis and Doebley), indicating that maize has evolved adaptability beyond the environmental range in which ancestral maize was first domesticated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Source: ORCID
Added: December 8, 2020
2008 journal article
A comparison of leaf appearance rates among teosinte, maize landraces and modern maize
Maydica, 53(2), 117–123. http://www.scopus.com/inward/record.url?eid=2-s2.0-57849127135&partnerID=MN8TOARS
Contributors: G. Van Esbroeck, J. Ruiz Corral, J. Sanchez Gonzalez & J. Holland
Source: ORCID
Added: December 8, 2020
2008 journal article
Interactions between nectar robbers and seed predators mediated by a shared host plant, Ipomopsis aggregata
Oecologia, 155(1), 75–84.
author keywords: scarlet gilia; multispecies interactions; nectar robbing; plant-animal interactions; pollination
MeSH headings : Animals; Bees / physiology; Diptera / physiology; Flowers / parasitology; Fruit / parasitology; Host-Parasite Interactions / physiology; Magnoliopsida / parasitology; Magnoliopsida / physiology; Predatory Behavior; Seeds / parasitology
TL;DR:
The results suggest that seed predation is not independent of nectar robbing, and accounting for the interactions among species is crucial to predicting their ecological effects and plant evolutionary response.
(via Semantic Scholar)
Source: Crossref
Added: October 29, 2020
2008 journal article
Plasma fatty acid concentrations in Boxers and Doberman Pinschers
American Journal of Veterinary Research, 69(2), 195–198.
MeSH headings : Animals; Arrhythmias, Cardiac / blood; Arrhythmias, Cardiac / veterinary; Dog Diseases / blood; Dogs / blood; Dogs / genetics; Fatty Acids / blood; Female; Male
TL;DR:
It is suggested that plasma fatty acid concentrations may differ between Boxers and Doberman Pinschers and that the relationship between fatty Acid concentrations and VPCs may be different between these 2 breeds.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: October 18, 2020
2008 journal article
Alien genetic resources for wheat leaf rust resistance, cytogenetic transfer, and molecular analysis
Australian Journal of Agricultural Research, 59(3), 197.
TL;DR:
The objective of this review is to document research on the evaluation, transfer, and molecular analysis of alien resistance to wheat leaf rust especially in Aegilops tauschii, the diploid D-genome donor of common wheat.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020
2008 journal article
Evidence for Positive Selection in Putative Virulence Factors within the Paracoccidioides brasiliensis Species Complex
PLoS Negl Trop Dis, 2(9), e296.
Ed(s): J. Taylor
MeSH headings : DNA Mutational Analysis; DNA, Fungal / genetics; DNA, Fungal / isolation & purification; Genes, Fungal; Genetic Variation; Genome, Fungal; Humans; Latin America / epidemiology; Likelihood Functions; Models, Genetic; Paracoccidioides / classification; Paracoccidioides / genetics; Paracoccidioides / pathogenicity; Paracoccidioidomycosis / epidemiology; Paracoccidioidomycosis / prevention & control; Phylogeny; Selection, Genetic; Virulence / genetics
Source: ORCID
Added: September 8, 2020
2008 journal article
Does strong linkage disequilibrium guarantee redundant association results?
Genetic Epidemiology, 32(6), 546–552.
author keywords: linkage disequilibrium; association mapping; negative correlation; case control; transmission disequilibrium
MeSH headings : Computer Simulation; Gene Frequency; Genetic Markers; Genome, Human; Haplotypes; Humans; Linkage Disequilibrium; Models, Genetic; Models, Statistical; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable
TL;DR:
This work finds that in the null hypothesis situation, where there is no association between the markers and the phenotype, the relationship between LD and the correlation between association test outcomes is clear, though it is not always ideal.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, ORCID
Added: September 5, 2020
2008 journal article
DNA-Templated Polymerization of Side-Chain-Functionalized Peptide Nucleic Acid Aldehydes
Journal of the American Chemical Society, 130(14), 4646–4659.
MeSH headings : Aldehydes / chemical synthesis; Aldehydes / chemistry; DNA / chemical synthesis; DNA / chemistry; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Nucleic Acid Conformation; Peptide Nucleic Acids / chemistry; Polymers / chemical synthesis; Spectrometry, Mass, Electrospray Ionization
TL;DR:
The findings represent a significant step toward the evolution of sequence-defined synthetic polymers and also demonstrate that enzyme-free nucleic acid-templated polymerization can occur efficiently using substrates with a wide range of side-chain structures, functionalization positions within each building block, and functionalization densities.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 28, 2020
2008 journal article
Septate junctions are required for ommatidial integrity and blood–eye barrier function in Drosophila
Developmental Biology, 317(2), 585–599.
author keywords: ommatidium; photoreceptors; cone cells; pigment cells; neurexin IV
MeSH headings : Animals; Blood-Retinal Barrier / physiology; Cell Adhesion Molecules, Neuronal / deficiency; Cell Adhesion Molecules, Neuronal / genetics; Cell Adhesion Molecules, Neuronal / metabolism; Compound Eye, Arthropod / physiology; Compound Eye, Arthropod / ultrastructure; DNA Primers / genetics; Drosophila / physiology; Drosophila Proteins / deficiency; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Gene Components; Immunohistochemistry; Microscopy, Electron; Mutation / genetics; Photoreceptor Cells, Invertebrate / physiology; Photoreceptor Cells, Invertebrate / ultrastructure; Sequence Analysis, DNA; Tight Junctions / metabolism; Tight Junctions / physiology; Tight Junctions / ultrastructure
TL;DR:
It is established that septate junctions (SJs), the vertebrate analogs of TJs, are present in the adult ommatidia and are formed between and among the cone and pigment cells.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
T1820 Enteric Glial Cells Promote Wound Healing of Intestinal Epithelial Barrier in Part Via a FAK-Dependent Pathway
Gastroenterology, 134(4), A-570.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Crossref
Added: August 28, 2020
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