Genetics and Genomics Academy

Interdisciplinary Programs

Works Published in 2010

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Displaying works 81 - 100 of 423 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2010 journal article

Correlating Aggregation Kinetics and Stationary Diffusion in Protein−Sodium Salt Systems Observed with Dynamic Light Scattering

The Journal of Physical Chemistry B, 114(12), 4383–4387.

MeSH headings : Kinetics; Light; Proteins / chemistry; Salts / chemistry; Scattering, Radiation
Sources: Crossref, ORCID
Added: August 28, 2020

2010 journal article

A Genetic Strategy for Graded and Dynamic Control of Cell-Matrix Mechanobiology

Biophysical Journal, 98(3), 730a.

By: J. MacKay*, A. Keung* & S. Kumar*

Source: Crossref
Added: August 28, 2020

2010 journal article

Mechanotransductive Engineering of Neural Stem Cell Behavior

Biophysical Journal, 98(3), 404a–405a.

By: A. Keung*, E. de Juan-Pardo*, D. Schaffer* & S. Kumar*

Source: Crossref
Added: August 28, 2020

2010 journal article

Biophysics and dynamics of natural and engineered stem cell microenvironments

Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2(1), 49–64.

MeSH headings : Adult; Animals; Biomechanical Phenomena / physiology; Biophysics / methods; Biophysics / trends; Cell Culture Techniques / methods; Environment; Humans; Kinetics; Models, Biological; Stem Cells / cytology; Stem Cells / metabolism; Stem Cells / physiology; Tissue Engineering / methods
Source: Crossref
Added: August 28, 2020

2010 journal article

Gestational exposure to bisphenol A and cross-fostering affect behaviors in juvenile mice

Hormones and Behavior, 58(5), 754–761.

By: K. Cox*, J. Gatewood*, C. Howeth* & E. Rissman*

author keywords: Endocrine disruptive compounds; Estrogens; Epigenetic; Environment; Methylation; Sex differences; Bisphenol A
MeSH headings : Air Pollutants / toxicity; Animal Husbandry; Animals; Animals, Newborn; Anxiety / chemically induced; Behavior, Animal / drug effects; Behavior, Animal / physiology; Benzhydryl Compounds; Exploratory Behavior / drug effects; Exploratory Behavior / physiology; Female; Male; Maternal Deprivation; Maternal Exposure / adverse effects; Maze Learning / drug effects; Maze Learning / physiology; Mice; Mice, Inbred C57BL; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / physiopathology; Prenatal Exposure Delayed Effects / psychology
Source: Crossref
Added: August 28, 2020

2010 journal article

Of mice and rats: Key species variations in the sexual differentiation of brain and behavior

Frontiers in Neuroendocrinology, 31(3), 341–358.

By: P. Bonthuis*, K. Cox*, B. Searcy*, P. Kumar*, S. Tobet* & E. Rissman*

author keywords: Hypothalamus; Calbindin D28k; Progestin receptor; Estrogen receptor; Nitric oxide; Sexual dimorphism
MeSH headings : Animals; Behavior, Animal / physiology; Brain / growth & development; Brain / physiology; Humans; Mice; Models, Animal; Rats; Sex Differentiation / physiology; Sexual Behavior, Animal / physiology; Species Specificity
Source: Crossref
Added: August 28, 2020

2010 journal article

Critical periods of susceptibility to short-term energy challenge during pregnancy: Impact on fertility and offspring development

Physiology & Behavior, 99(1), 100–108.

author keywords: Reproduction; Pregnancy; Fertility; Gestation; Delayed implantation; Energy balance; Food restriction; Sexual behavior; Development
MeSH headings : Analysis of Variance; Animals; Body Weight; Disease Susceptibility; Eating / physiology; Fasting / physiology; Female; Fertility / physiology; Fetal Development / physiology; Litter Size; Male; Nutritional Status; Pregnancy / physiology; Pregnancy Outcome; Pregnancy, Animal; Sexual Behavior, Animal; Shrews; Time Factors
Source: Crossref
Added: August 28, 2020

2010 journal article

Maternally-inherited Grb10 reduces placental size and efficiency

Developmental Biology, 337(1), 1–8.

By: M. Charalambous*, M. Cowley*, F. Geoghegan*, F. Smith*, E. Radford*, B. Marlow*, C. Graham*, L. Hurst*, A. Ward*

author keywords: Adapter protein; Cell signalling; Epigenetics; Genomic imprinting; Growth factor receptor-bound protein; Growth regulation; IGF; Insulin-like growth factor; Mouse; Placenta
MeSH headings : Alleles; Animals; Endothelium / metabolism; Female; GRB10 Adaptor Protein / analysis; GRB10 Adaptor Protein / genetics; GRB10 Adaptor Protein / physiology; Genomic Imprinting; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Placenta / pathology; Placenta / physiology; Pregnancy
Sources: Crossref, ORCID
Added: August 28, 2020

2010 journal article

Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species

Chemical Research in Toxicology, 23(1), 171–183.

By: D. Fourches*, J. Barnes*, N. Day*, P. Bradley*, J. Reed* & A. Tropsha*

MeSH headings : Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship
Source: Crossref
Added: August 28, 2020

2010 journal article

Quantitative Nanostructure−Activity Relationship Modeling

ACS Nano, 4(10), 5703–5712.

By: D. Fourches*, D. Pu*, C. Tassa*, R. Weissleder*, S. Shaw*, R. Mumper*, A. Tropsha*

author keywords: nanoparticles; QSAR; cheminformatics; nanotoxicity; modeling
MeSH headings : Animals; Cell Line, Tumor; Humans; Metal Nanoparticles / chemistry; Microscopy, Atomic Force / methods; Models, Statistical; Models, Theoretical; Nanotechnology / methods; Oxides / chemistry; Quantitative Structure-Activity Relationship; Rats; Regression Analysis; Surface Properties; U937 Cells
Source: Crossref
Added: August 28, 2020

2010 journal article

Applicability Domains for Classification Problems: Benchmarking of Distance to Models for Ames Mutagenicity Set

Journal of Chemical Information and Modeling, 50(12), 2094–2111.

By: I. Sushko*, S. Novotarskyi*, R. Körner*, A. Pandey*, A. Cherkasov*, J. Li*, P. Gramatica*, K. Hansen* ...

MeSH headings : Benchmarking / methods; Classification / methods; Mutagenicity Tests / methods; Mutagenicity Tests / standards; Principal Component Analysis; Quantitative Structure-Activity Relationship
Source: Crossref
Added: August 28, 2020

2010 journal article

Trust, But Verify: On the Importance of Chemical Structure Curation in Cheminformatics and QSAR Modeling Research

Journal of Chemical Information and Modeling, 50(7), 1189–1204.

By: D. Fourches*, E. Muratov & A. Tropsha

MeSH headings : Animals; Models, Chemical; Molecular Structure; Organometallic Compounds / chemistry; Quantitative Structure-Activity Relationship
Source: Crossref
Added: August 28, 2020

2010 journal article

Interactome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus

Proceedings of the National Academy of Sciences, 107(10), 4693–4698.

By: P. Shea*, K. Virtaneva*, J. Kupko*, S. Porcella*, W. Barry*, F. Wright*, S. Kobayashi, A. Carmody* ...

author keywords: epithelial growth factor receptor; host pathogen; microarray; Streptococcus pyogenes; transcriptome
MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Clathrin-Coated Vesicles / metabolism; Cytokines / metabolism; GTP Phosphohydrolases / genetics; GTP Phosphohydrolases / metabolism; Gene Expression Profiling; Host-Pathogen Interactions; Hyaluronic Acid / metabolism; Macaca fascicularis / genetics; Macaca fascicularis / metabolism; Macaca fascicularis / microbiology; Neutrophils / metabolism; Neutrophils / microbiology; Neutrophils / pathology; Oligonucleotide Array Sequence Analysis; Pharyngitis / genetics; Pharyngitis / microbiology; Pharynx / metabolism; Pharynx / microbiology; Pharynx / pathology; Reverse Transcriptase Polymerase Chain Reaction; Streptococcus pyogenes / genetics; Streptococcus pyogenes / metabolism; Streptococcus pyogenes / physiology
Source: Crossref
Added: August 28, 2020

2010 journal article

Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans

Clinical Pharmacology & Therapeutics, 88(1), 45–51.

By: J. Winnike*, Z. Li*, F. Wright*, J. Macdonald*, T. O'Connell* & P. Watkins*

MeSH headings : Acetaminophen / adverse effects; Acetaminophen / metabolism; Acetaminophen / pharmacology; Adolescent; Adult; Alanine Transaminase / blood; Analgesics, Non-Narcotic / adverse effects; Analgesics, Non-Narcotic / metabolism; Analgesics, Non-Narcotic / pharmacology; Biotransformation; Chemical and Drug Induced Liver Injury / diagnosis; Chemical and Drug Induced Liver Injury / genetics; Chemical and Drug Induced Liver Injury / urine; Cohort Studies; Data Interpretation, Statistical; Female; Humans; Least-Squares Analysis; Liver Function Tests; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Young Adult
Source: Crossref
Added: August 28, 2020

2010 journal article

An approximate Bayesian approach for quantitative trait loci estimation

Computational Statistics & Data Analysis, 54(2), 565–574.

By: Y. Chang*, F. Zou* & F. Wright*

Source: Crossref
Added: August 28, 2020

2010 journal article

Heterotaxin: A novel TGF-beta signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos

Developmental Biology, 344(1), 526.

By: N. Nascone-Yoder*, M. Dush, A. McIver n, M. Parr, D. Young n, J. Fisher, M. Hauck, A. Deiters n

Source: Crossref
Added: August 28, 2020

2010 journal article

Differential response in foliar chemistry of three ash species to emerald ash borer adult feeding.

Journal of Chemical Ecology, 1.

author keywords: Agrilus planipennis; Fraxinus; Plant defense; Phenolics; Volatile organic compounds; VOCs; Coleoptera; Buprestidae
MeSH headings : Animals; Chromatography, High Pressure Liquid; Coleoptera / physiology; Feeding Behavior; Female; Fraxinus / chemistry; Fraxinus / parasitology; Plant Leaves / chemistry; Plant Leaves / parasitology; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Volatile Organic Compounds / analysis
Source: ORCID
Added: August 24, 2020

2010 journal article

W1250 Genome-Wide Association Scan Reveals Polymorphisms in the P67phox Subunit (Ncf2) of the NADPH Oxidase Complex in Boxer Dogs With Adherent and Invasive E.Coli-Associated Granulomatous Colitis: A Potential Model of Chronic Granulomatous Disease

Gastroenterology, 138(5), S-683.

By: M. Craven, G. Acland, J. Mezey, A. Boyko, W. Wang, K. Meurs*, S. McDonough, K. Simpson

Sources: Crossref, ORCID
Added: March 8, 2020

2010 journal article

Genetics of Cardiac Disease in the Small Animal Patient

Veterinary Clinics of North America: Small Animal Practice, 40(4), 701–715.

By: K. Meurs*

author keywords: Familial; Mutation; Cardiomyopathy; Congenital heart disease
MeSH headings : Animals; Breeding; Cat Diseases / genetics; Cat Diseases / prevention & control; Cats; Dog Diseases / genetics; Dog Diseases / prevention & control; Dogs; Female; Genetic Diseases, Inborn / prevention & control; Genetic Diseases, Inborn / veterinary; Genetic Predisposition to Disease; Heart Diseases / genetics; Heart Diseases / prevention & control; Heart Diseases / veterinary; Male; Selection, Genetic
Sources: Crossref, ORCID
Added: March 8, 2020

2010 journal article

Spatiotemporal regulation of cell-cycle genes by SHORTROOT links patterning and growth

Nature, 466(7302), 128–132.

MeSH headings : Arabidopsis / cytology; Arabidopsis / embryology; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Body Patterning / genetics; Body Patterning / physiology; Cell Cycle / genetics; Cell Cycle / physiology; Cell Division / genetics; Cyclin D / genetics; Cyclin D / metabolism; Cyclin-Dependent Kinases / metabolism; Gene Expression Regulation, Plant; Genes, cdc / physiology; Organogenesis / genetics; Organogenesis / physiology; Plant Roots / cytology; Plant Roots / embryology; Plant Roots / genetics; Plant Roots / growth & development; Time Factors; Transcription Factors / genetics; Transcription Factors / metabolism
Sources: Crossref, ORCID
Added: March 5, 2020