Works Published in 2012

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Displaying works 81 - 100 of 613 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2012 report

Genetically Modified Foods: Policy Context and Safety

(Policy Brief No. 1). Food Policy Research Center.

By: J. Kuzma & R. Haase

Source: NC State University Libraries
Added: February 9, 2021

2012 journal article

Physiological studies on the sex-linked dwarfism of the fowl: A review on the search for the gene's primary effect.

Asian Journal of Animal and Veterinary Advances, 11(9), 1785–1794.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2012 article

Global Gene Expression Analysis of Long and Short Day 15 Bovine Conceptuses Produced In Vivo.

Oxford University Press.

By: C. Barnwell, C. Ashwell, P. Farin, W. Farmer & C. Farin

Source: ORCID
Added: February 4, 2021

2012 conference paper

Genome-wide methylation analysis of chicken primordial germ cells

Plant and Animal Genome XX Conference, January, 14–18.

By: C. Ashwell

Source: ORCID
Added: February 4, 2021

2012 journal article

Direct fed microbial supplementation repartitions host energy to the immune system

Journal of Animal Science, 90(8), 2639–2651.

Chris Ashwell

Source: ORCID
Added: February 4, 2021

2012 journal article

Actigen Influence on the Gene Expression of Heat Shock Proteins in Ross 708 Broiler Chickens.

By: Z. Lowman & others

Source: ORCID
Added: February 4, 2021

2012 journal article

N-(pyridin-4-yl)benzo[d]thiazole-6-carboxamide inhibits E. coli UT189 bacterial capsule biogenesis

Probe Reports from the NIH Molecular Libraries Program. https://www.ncbi.nlm.nih.gov/books/NBK148500/

By: J. Noah, S. Ananthan, C. Evans, N. Nebane, L. Rasmussen, M. Sosa, N. Tower, E. White ...

Source: NC State University Libraries
Added: January 30, 2021

2012 journal article

UDP-glucose Dehydrogenase Polymorphisms from Patients with Congenital Heart Valve Defects Disrupt Enzyme Stability and Quaternary Assembly

Journal of Biological Chemistry, 287(39), 32708–32716.

By: A. Hyde*, E. Farmer*, K. Easley*, K. van Lammeren*, V. Christoffels*, J. Barycki*, J. Bakkers*, M. Simpson*

MeSH headings : Amino Acid Substitution; Animals; Animals, Genetically Modified / embryology; Animals, Genetically Modified / genetics; Enzyme Stability / genetics; Escherichia coli; Heart Defects, Congenital / embryology; Heart Defects, Congenital / enzymology; Heart Defects, Congenital / genetics; Heart Valve Diseases / embryology; Heart Valve Diseases / enzymology; Heart Valve Diseases / genetics; Heart Valves / embryology; Heart Valves / enzymology; Muscle Proteins / genetics; Muscle Proteins / metabolism; Mutation, Missense; Polymorphism, Genetic; Protein Structure, Quaternary; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Uridine Diphosphate Glucose Dehydrogenase; Zebrafish / embryology; Zebrafish / genetics; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
TL;DR: UGDH loss of function mutations result in a subset of human congenital cardiac valve defects caused by reduced enzyme activity during morphogenesis, consistent with the reduced function of both missense mutations significantly reducing the ability of UGDH to provide precursors for cardiac cushion formation, which is essential to subsequent valve formation. (via Semantic Scholar)
Source: Crossref
Added: January 30, 2021

2012 journal article

Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves

Pathology - Research and Practice, 208(11), 642–650.

By: E. Stephens*, J. Saltarrelli Jr, L. Balaoing*, L. Baggett*, I. Nandi*, K. Anderson*, J. Morrisett*, M. Reardon* ...

author keywords: Brown adipocytes; Hyaluronan; Hypoxia; Calcification; Aortic valve
MeSH headings : Adipocytes, Brown / metabolism; Adipocytes, Brown / pathology; Aged; Aortic Valve / metabolism; Aortic Valve / pathology; Aortic Valve / surgery; Aortic Valve Stenosis / metabolism; Aortic Valve Stenosis / pathology; Biomarkers / metabolism; Calcinosis / etiology; Calcinosis / metabolism; Calcinosis / pathology; Cell Adhesion Molecules / metabolism; Cell Differentiation; Female; Glucuronosyltransferase / metabolism; Homeostasis / physiology; Humans; Hyaluronan Synthases; Hyaluronic Acid / metabolism; Hyaluronoglucosaminidase / metabolism; Hypoxia / metabolism; Male; Ossification, Heterotopic / metabolism; Ossification, Heterotopic / pathology
TL;DR: Roles for hyaluronan homeostasis and the promotion of hypoxia by cells demonstrating brown fat markers in calcific aortic valve disease are suggested. (via Semantic Scholar)
Source: Crossref
Added: January 30, 2021

2012 journal article

Systemic blockade of the hyaluronan receptor for endocytosis prevents lymph node metastasis of prostate cancer

International Journal of Cancer, 131(5), E836–E840.

By: M. Simpson*, J. Weigel* & P. Weigel*

author keywords: prostate cancer; hyaluronan; metastasis; HARE; Stab2; Stabilin 2; mouse orthotopic model
MeSH headings : Adenocarcinoma / immunology; Adenocarcinoma / prevention & control; Adenocarcinoma / secondary; Animals; Antibodies, Monoclonal / therapeutic use; Cell Adhesion Molecules, Neuronal / antagonists & inhibitors; Cell Adhesion Molecules, Neuronal / immunology; Endocytosis; Humans; Hyaluronic Acid / metabolism; Lymph Nodes / drug effects; Lymph Nodes / metabolism; Lymph Nodes / pathology; Lymphatic Metastasis; Male; Mice; Mice, Inbred NOD; Mice, SCID; Prostatic Neoplasms / immunology; Prostatic Neoplasms / pathology; Prostatic Neoplasms / prevention & control; Tumor Cells, Cultured
TL;DR: The results implicate HARE for the first time in potentiation of tumor metastasis and suggest a novel mechanism by which tumor cell‐associated HA could promote tissue‐specific dissemination. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: January 30, 2021

2012 report

3-(2,6-difluorobenzamido)-5-(4-ethoxyphenyl) thiophene-2-carboxylic acid inhibits E.coli UT189 bacterial capsule biogenesis

In Probe Reports from the NIH Molecular Libraries Program. https://www.ncbi.nlm.nih.gov/books/NBK143534/

By: J. Noah, S. Ananthan, C. Evans, N. Nebane, L. Rasmussen, M. Sosa, N. Tower, E. White ...

Source: NC State University Libraries
Added: January 28, 2021

2012 journal article

CIRCADIAN CLOCK-ASSOCIATED 1 regulates ROS homeostasis and oxidative stress responses.

Proceedings of the National Academy of Sciences of the United States of America.

Colleen Doherty

author keywords: redox homeostasis; transcriptional coordination
MeSH headings : Arabidopsis / physiology; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Arabidopsis Proteins / physiology; Chromatin Immunoprecipitation; Computational Biology; Gene Expression Regulation, Plant / genetics; Gene Expression Regulation, Plant / physiology; Homeostasis / genetics; Homeostasis / physiology; Luminescent Measurements; Mutation / genetics; Oxidative Stress / physiology; Polymerase Chain Reaction; Reactive Oxygen Species / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism; Transcription Factors / physiology
TL;DR: This work proposes CCA1 as a master regulator of ROS homeostasis through association with the Evening Element in promoters of ROS genes in vivo to coordinate time-dependent responses to oxidative stress. (via Semantic Scholar)
Source: ORCID
Added: January 25, 2021

2012 journal article

Circadian surprise--it's not all about transcription.

Science (New York, N.Y.).

Colleen Doherty

MeSH headings : Animals; CLOCK Proteins / genetics; Chromatin / metabolism; Circadian Clocks / genetics; Circadian Rhythm / genetics; Cryptochromes / genetics; Epigenesis, Genetic; Gene Expression Regulation; Liver / physiology; Male; RNA-Binding Proteins / metabolism; Transcription, Genetic; Transcriptional Activation
TL;DR: This issue focuses on the importance of posttranscriptional regulation of messenger RNA levels on the clock, and investigates this problem from opposite ends of the spectrum—a genome-wide discovery approach and the functional characterization of a specific factor. (via Semantic Scholar)
Source: ORCID
Added: January 25, 2021

2012 journal article

Ileocecal resection (ICR)-driven crypt fission requires intestinal epithelial IGF-1 receptor, is increased with delayed IGF-1 therapy, and results in sustained adaptive increases in body weight and intestinal length

Journal of the American College of Surgeons, 215(3), S77.

By: M. Stevenson*, J. Hawkins*, N. Sundaram*, P. Lund*, L. Van Landeghem* & M. Helmrath*

TL;DR: Obese patients were more likely older, black or Hispanic, living in lower income neighborhoods, and using Medicaid, and more likely to undergo laparoscopic appendectomy than non-obese patients. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Crossref
Added: January 21, 2021

2012 journal article

Integration of GC-MS Based Non-Targeted Metabolic Profiling with Headspace Solid Phase Microextraction Enhances the Understanding of Volatile Differentiation in Tobacco Leaves from North Carolina, India and Brazil

American Journal of Plant Sciences, 03(12), 1759–1769.

By: D. Ma n, S. Gandra*, N. Sharma* & D. Xie n

TL;DR: Gas chromatography-mass spectrometry based non-targeted metabolomics is used to develop appropriate headspace solid phase microextractions (HS-SPME) to enhance the understanding of volatile complexity of flue-cured tobacco leaves. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: January 21, 2021

2012 journal article

Human Intestinal Transporter Database: QSAR Modeling and Virtual Profiling of Drug Uptake, Efflux and Interactions

Pharmaceutical Research, 30(4), 996–1007.

By: A. Sedykh*, D. Fourches*, J. Duan*, O. Hucke*, M. Garneau*, H. Zhu*, P. Bonneau*, A. Tropsha*

author keywords: ADMET; drug transport; efflux; membrane transport proteins; permeability
MeSH headings : Artificial Intelligence; Biological Transport, Active; Computer Simulation; Databases, Pharmaceutical; Databases, Protein; Humans; Intestinal Mucosa / metabolism; Membrane Transport Proteins / chemistry; Membrane Transport Proteins / metabolism; Models, Biological; Pharmaceutical Preparations / chemistry; Pharmaceutical Preparations / metabolism; Pharmacokinetics; Quantitative Structure-Activity Relationship
TL;DR: The compendium of predictive QSAR models developed in this study can be used for virtual profiling of drug candidates and/or environmental agents with the optimal transporter profiles with high prediction accuracies in the virtual screening of DrugBank compounds. (via Semantic Scholar)
Source: Crossref
Added: January 21, 2021

2012 journal article

Small mammal use of field borders planted as beneficial insect habitat

Wildlife Society Bulletin, 37(1), 209–215.

By: C. Moorman n, C. Plush n, D. Orr n, C. Reberg-Horton n & B. Gardner n

author keywords: agriculture; beneficial insects; field borders; Mus musculus; Sigmodon hispidus; small mammals
TL;DR: Lower abundance of cotton rats and house mice in mowed borders emphasizes the importance of structurally complex non-crop vegetation for supporting small-mammal communities in agricultural landscapes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Crossref
Added: January 21, 2021

2012 report

Renaming the dollar spot fungus

Golf Course Management Current Research.

By: L. Beirn, B. Clarke, L. Tredway, I. Carbone, M. Boehm, A. Orshinsky, J. Crouch

Source: NC State University Libraries
Added: January 17, 2021

2012 journal article

Why an old foe simply won't go away

New Scientist, 215(2874), 52.

By: R. Dunn*

Sources: Crossref, ORCID
Added: January 5, 2021

2012 chapter

Engineering Glycosyltransferases

In S. Lutz & U. T. Bornscheuer (Eds.), The Protein Engineering Handbook (Vol. 3, pp. 303–326). Weinheim: Wiley-HCH.

By: J. McArthur & G. Williams

Ed(s): S. Lutz & U. Bornscheuer

Source: NC State University Libraries
Added: December 30, 2020

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