Works Published in 2008
Displaying works 101 - 120 of 473 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2008 journal article
Evaluation of the field impact of an adventitious herbivore on an invasive plant, yellow toadflax, in Colorado, USA
Plant Ecology, 199(1), 99–114.
author keywords: biological Control; Brachypterolus pulicarius; herbivory; insect behavior; invasive; Linaria vulgaris
TL;DR:
The effects of an accidentally introduced beetle Brachypterolus pulicarius on the growth and reproduction of its host, the invasive plant Linaria vulgaris, growing under field conditions across multiple years and sites in western Colorado, USA are studied.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2008 journal article
Aggressive behaviors in adult SF-1 knockout mice that are not exposed to gonadal steroids during development.
Behavioral Neuroscience, 122(4), 876–884.
author keywords: sexual differentiation; VMH; steroidogenic factor 1; sex steroids; aggression
MeSH headings : Adrenal Cortex Hormones / pharmacology; Adrenal Glands / transplantation; Age Factors; Aggression / drug effects; Aggression / physiology; Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal / drug effects; Behavior, Animal / physiology; Castration / methods; Female; Male; Mice; Mice, Knockout; Sex Differentiation / drug effects; Sex Differentiation / physiology; Steroidogenic Factor 1 / deficiency
TL;DR:
In the absence of sex steroid replacement, adult SF-1 KO mice were significantly more aggressive than control mice in tests with stimulus females, and after testosterone treatment, control males displayed significantly more aggression towards male intruders than control female mice.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2008 journal article
Sex chromosome complement affects social interactions in mice
Hormones and Behavior, 54(4), 565–570.
author keywords: affective disorders; autism; depression; anxiety; sexual differentiation; X inactivation; cognition; pain
MeSH headings : Animals; Anxiety / genetics; Anxiety / physiopathology; Behavior, Animal / physiology; Disorders of Sex Development / genetics; Disorders of Sex Development / physiopathology; Disorders of Sex Development / veterinary; Feeding Behavior / physiology; Female; Genes, sry / physiology; Male; Mice; Mice, Inbred C57BL; Motor Activity / genetics; Motor Activity / physiology; Psychomotor Performance / physiology; Sex Chromosome Aberrations; Social Behavior; Y Chromosome
TL;DR:
Data show that sex chromosome complement affects social interaction style in mice, and differences in circulating levels of gonadal steroids cannot account for these effects.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Neuropeptide Y influences acute food intake and energy status affects NPY immunoreactivity in the female musk shrew (Suncus murinus)
Hormones and Behavior, 53(2), 342–350.
author keywords: obesity; anorexia; orexins; energy; feeding disorder; mating behavior; reproduction; gonadotropin releasing hormone; GnRH II
MeSH headings : Animals; Appetite Regulation / physiology; Brain / metabolism; Dose-Response Relationship, Drug; Energy Metabolism / physiology; Feeding Behavior / physiology; Female; Food Deprivation / physiology; Gonadotropin-Releasing Hormone / analogs & derivatives; Gonadotropin-Releasing Hormone / metabolism; Immunohistochemistry; Injections, Intraventricular; Neuropeptide Y / administration & dosage; Neuropeptide Y / physiology; Sexual Behavior, Animal / physiology; Shrews / metabolism; Tissue Distribution
TL;DR:
It is hypothesize that interactions between NPY and GnRH II maintain energy homeostasis and reproduction in the musk shrew.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Diversity of actions of GnRHs mediated by ligand-induced selective signaling
Frontiers in Neuroendocrinology, 29(1), 17–35.
author keywords: GnRH; GnRH receptor; ligand-induced selective-signaling; reproduction; antiproliferation; GPCR; signal trafficking; cancer
MeSH headings : Amino Acid Sequence; Animals; Apoptosis / drug effects; Cell Proliferation / drug effects; Gene Silencing; Gonadotropin-Releasing Hormone / analogs & derivatives; Gonadotropin-Releasing Hormone / chemistry; Gonadotropin-Releasing Hormone / pharmacology; Gonadotropin-Releasing Hormone / physiology; Humans; Ligands; Models, Biological; Models, Molecular; Molecular Sequence Data; Neoplasms / pathology; Protein Isoforms / chemistry; Protein Isoforms / physiology; Receptors, LHRH / agonists; Receptors, LHRH / physiology; Reproductive Behavior / drug effects; Reproductive Behavior / physiology; Sequence Homology, Amino Acid; Sexual Behavior, Animal / drug effects; Sexual Behavior, Animal / physiology; Signal Transduction / drug effects; Signal Transduction / physiology; Structure-Activity Relationship; Substrate Specificity
TL;DR:
It is proposed that the GnRH receptor can assume different conformations which have different selectivity for GnRH analogs and intracellular signaling proteins complexes and this ligand-induced selective-signaling recruits certain pathways while by-passing others and has implications in developing more selective Gn RH analogs for highly specific therapeutic intervention.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2008 journal article
Regulation of food intake by gonadotropin releasing hormone II in an animal model of binge eating disorder
Appetite, 51(2), 398.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2008 journal article
Critical Assessment of QSAR Models of Environmental Toxicity against Tetrahymena pyriformis: Focusing on Applicability Domain and Overfitting by Variable Selection
Journal of Chemical Information and Modeling, 48(9), 1733–1746.
MeSH headings : Animals; Computer Simulation; Databases, Factual; Environmental Pollutants / chemistry; Environmental Pollutants / toxicity; Models, Biological; Models, Statistical; Normal Distribution; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Reproducibility of Results; Tetrahymena pyriformis / drug effects; Toxicity Tests / standards
TL;DR:
It is shown that incorrect validation of a model may result in the wrong estimation of its performance and suggested how this problem could be circumvented and the distance to model metric could also be used to augment mechanistic QSAR models by estimating their prediction errors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2008 journal article
Combinatorial QSAR Modeling of Chemical Toxicants Tested against Tetrahymena pyriformis
Journal of Chemical Information and Modeling, 48(4), 766–784.
MeSH headings : Animals; Combinatorial Chemistry Techniques; Quantitative Structure-Activity Relationship; Tetrahymena pyriformis / drug effects; Toxicity Tests
TL;DR:
An international virtual collaboratory consisting of six independent groups with shared interests in computational chemical toxicology develops 15 different types of QSAR models of aquatic toxicity and finds that consensus models afford higher prediction accuracy for the external validation data sets with the highest space coverage as compared to individual constituent models.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Estimating Odds Ratios in Genome Scans: An Approximate Conditional Likelihood Approach
The American Journal of Human Genetics, 82(5), 1224.
Source: Crossref
Added: August 28, 2020
2008 journal article
Estimating Odds Ratios in Genome Scans: An Approximate Conditional Likelihood Approach
The American Journal of Human Genetics, 82(5), 1064–1074.
MeSH headings : Genome, Human; Haplotypes; Humans; Likelihood Functions; Models, Genetic; Odds Ratio; Software
TL;DR:
This work introduces a method, based on the estimate of genetic effect and its standard error as reported by standard statistical software, to correct for this bias in case-control association studies and develops a principled method to construct confidence intervals for the genetic effect that acknowledges the conditioning on statistical significance.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Comment on a Simple and Improved Correction for Population Stratification
The American Journal of Human Genetics, 82(2), 524–526.
MeSH headings : Case-Control Studies; Genetic Markers; Genetics, Population; Genotype; Humans; Polymorphism, Single Nucleotide; Regression Analysis; Research Design
TL;DR:
To the Editor: In the May 2007 issue of the American Journal of Human Genetics, Epstein, Allen, and Satten1 (hereafter referred to as EAS) introduced a new method for controlling population stratification in case-control association studies.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
The Mitochondrial Targeted GS-Nitroxide JP4-039 is Radioprotective In Vitro and In Vivo
International Journal of Radiation Oncology*Biology*Physics, 72(1), S82.
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2008 journal article
Non invasive high resolution in vivo imaging of α-naphthylisothiocyanate (ANIT) induced hepatobiliary toxicity in STII medaka
Aquatic Toxicology, 86(1), 20–37.
author keywords: fish; toxicology; hepatobiliary; liver; toxicity; medaka; ANIT; biliary; biliary toxicity; alpha-naphthylisothiocyanate; hepatotoxicity; piscine liver
MeSH headings : 1-Naphthylisothiocyanate / toxicity; Animals; Antibodies / metabolism; Apoptosis; Bile Ducts, Intrahepatic / drug effects; Bile Ducts, Intrahepatic / pathology; Bile Ducts, Intrahepatic / ultrastructure; Blood Vessels / drug effects; Epithelial Cells / cytology; Epithelial Cells / drug effects; Fluorescent Dyes / analysis; Image Processing, Computer-Assisted; Imaging, Three-Dimensional / veterinary; Liver / blood supply; Liver / drug effects; Liver / pathology; Liver / ultrastructure; Microscopy, Confocal / veterinary; Models, Animal; Oryzias / genetics; Oryzias / physiology; Phenotype
TL;DR:
The findings presented show for the first time in vivo evaluation of toxicity in the STII medaka hepatobiliary system, and, in conjunction with prior in vivo work characterizing normalcy, advance the comparative understanding of this lower vertebrate hepatOBiliary system and its response to toxic insult.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 28, 2020
2008 journal article
Basolumenal endoderm intercalation: A geometrically unique execution of convergent extension during gut tube elongation
Developmental Biology, 319(2), 513.
Source: Crossref
Added: August 28, 2020
2008 journal article
Heterotaxin: A novel pyridine compound that perturbs left–right asymmetric organ morphogenesis
Developmental Biology, 319(2), 513.
Source: Crossref
Added: August 28, 2020
2008 journal article
Small molecule-mediated “phenotypic engineering” reveals a role for retinoic acid in anuran gut evolution
Developmental Biology, 319(2), 497–498.
Source: Crossref
Added: August 28, 2020
2008 journal article
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo
Molecular Psychiatry, 14(4), 359–375.
author keywords: major depressive disorder; genome-wide association; Netherlands study of depression and anxiety; Netherlands twin registry
MeSH headings : Adult; Case-Control Studies; Cohort Studies; Cytoskeletal Proteins / genetics; Depressive Disorder, Major / genetics; Female; Genetic Linkage; Genetic Predisposition to Disease; Genome-Wide Association Study / methods; Humans; Male; Middle Aged; Neuropeptides / genetics; Polymorphism, Single Nucleotide / genetics
TL;DR:
A genome-wide association study of single nucleotide polymorphisms genotyped in 1738 MDD cases and 1802 controls selected to be at low liability for MDD found 11 signals localized to a 167 kb region overlapping the gene piccolo, whose protein product localizes to the cytomatrix of the presynaptic active zone and is important in monoaminergic neurotransmission in the brain.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: August 28, 2020
2008 journal article
Ecological correlates of risk and incidence of West Nile virus in the United States
Oecologia, 158(4), 699–708.
author keywords: Dilution effect; Disease ecology; Emerging infectious diseases; Ecosystem service
MeSH headings : Animals; Biodiversity; Birds / virology; Disease Outbreaks; Humans; Incidence; Population Density; Risk Assessment; United States; West Nile Fever / epidemiology; West Nile Fever / transmission; West Nile Fever / virology; West Nile virus / isolation & purification
TL;DR:
Prevalence of West Nile virus infection in mosquito vectors and in humans increased with decreasing bird diversity and with increasing reservoir competence of the bird community, and the results suggest that conservation of avian diversity might help ameliorate the currentWest Nile virus epidemic in the USA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: June 6, 2020
2008 conference paper
NIR responsive core/shell nanohybrids for smart drug delivery
8th World Biomaterials Congress 2008, 1, 297. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869034553&partnerID=MN8TOARS
Contributors: Q. Wei , J. Ji & J. Shen
Source: ORCID
Added: April 10, 2020
2008 journal article
Arabidopsis P-Glycoprotein19 Participates in the Inhibition of Gravitropism by Gravacin
Chemistry & Biology, 15(1), 87.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, ORCID
Added: March 5, 2020
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