Works Published in 2009
Displaying works 121 - 140 of 511 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2009 chapter
Analysis of Cis-Regulatory Motifs in Cassette Exons by Incorporating Exon Skipping Rates
In Bioinformatics Research and Applications (pp. 272–283).
TL;DR:
This study provides a dictionary of sequence motifs involved in the regulation of alternative splicing in CNS tissues, and a novel tool to detect such motifs, by applying a two-step approach to identify k-mer seed motifs.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 8, 2020
2009 chapter
Mining of cis-Regulatory Motifs Associated with Tissue-Specific Alternative Splicing
In Bioinformatics Research and Applications (pp. 260–271).
TL;DR:
This paper uses distribution-based quantitative association rule mining to find combinatorial cis -regulatory motifs and to investigate the effect of motif pairs, and shows that motifs that occur in motif pairs typically occur in clusters.
(via Semantic Scholar)
www.lib.ncsu.edu (repository)
Sources: Crossref, ORCID
Added: September 8, 2020
2009 journal article
Proceedings of the First International Conference on Toxicogenomics Integrated with Environmental Sciences (TIES-2007)
BMC Proceedings, 3(S2).
TL;DR:
A collection of articles as proceedings of the conference and an in-depth topical review of the utility of bioinformatics in the fields of toxicogenomics and environmental genomics are compiled.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 5, 2020
2009 journal article
Recent Progress Toward the Templated Synthesis and Directed Evolution of Sequence-Defined Synthetic Polymers
Chemistry & Biology, 16(3), 265–276.
MeSH headings : Base Sequence; Directed Molecular Evolution / methods; Directed Molecular Evolution / trends; Nucleic Acids / chemical synthesis; Nucleic Acids / chemistry; Nucleotides / chemical synthesis; Nucleotides / chemistry; Phosphates / chemical synthesis; Phosphates / chemistry; Polymers / chemical synthesis; Polymers / chemistry; Ribose / chemical synthesis; Ribose / chemistry; Ribosomes / metabolism
TL;DR:
This review covers recent advances in the enzymatic and nonenzymatic templated polymerization of nonnatural polymers and their potential applications in the directed evolution of sequence-defined synthetic polymers.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020
2009 journal article
The Type I interferon receptor protects against influenza virus replication while the Type II receptor is dispensible
Cytokine, 48(1-2), 83.
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2009 journal article
Ecogeographic genetic epidemiology
Genetic Epidemiology, 33(4), 281–289.
author keywords: geographic information systems; environmental health; population genetics; spatial genetics; medical geography; landscape genetics
MeSH headings : Ecosystem; Environment; Epidemiologic Methods; Genetics, Medical / statistics & numerical data; Genetics, Population / statistics & numerical data; Geography; Humans; Software
TL;DR:
A new interdisciplinary paradigm is introduced, ecogeographic genetic epidemiology, which uses GIS and spatial statistical analyses to layer genetic subpopulation and environmental data with disease rates and thereby discern the complex gene‐environment interactions which result in spatial patterns of incidence.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2009 journal article
Androgen- and estrogen-independent regulation of copulatory behavior following castration in male B6D2F1 mice
Hormones and Behavior, 56(2), 254–263.
author keywords: Male copulatory behavior; Sexual behavior; Partner preference; B6D2F1 hybrid mice; Libido; Androgen receptors; Aromatase; Estrogen receptors
MeSH headings : Androgen Antagonists / pharmacology; Androgen Receptor Antagonists; Androgens / metabolism; Animals; Aromatase / metabolism; Aromatase Inhibitors / pharmacology; Copulation / drug effects; Copulation / physiology; Estradiol / analogs & derivatives; Estradiol / pharmacology; Estrogen Antagonists / pharmacology; Estrogen Receptor alpha / antagonists & inhibitors; Estrogen Receptor alpha / metabolism; Estrogens / metabolism; Female; Flutamide / pharmacology; Fulvestrant; Letrozole; Male; Mating Preference, Animal / drug effects; Mating Preference, Animal / physiology; Mice; Nitriles / pharmacology; Orchiectomy; Preoptic Area / drug effects; Preoptic Area / physiology; RNA, Messenger / metabolism; Receptors, Androgen / metabolism; Septal Nuclei / drug effects; Septal Nuclei / physiology; Triazoles / pharmacology
TL;DR:
It is suggested that non-gonadal androgens and estrogens do not maintainCopulatory behavior in B6D2F1 mice which display copulatory behavior after castration, and this preference persisted after long-term castration in persistent copulators.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2009 journal article
Regulation of progestin receptors in medial amygdala: Estradiol, phytoestrogens and sex
Physiology & Behavior, 97(2), 146–150.
author keywords: Phytoestrogens; Environmental estrogens; Endocrine disrupting compounds; Progestin receptor; Medial amygdala; Sex differences; Sexual differentiation; Soy
MeSH headings : Amygdala / cytology; Amygdala / metabolism; Analysis of Variance; Animals; Aromatase / deficiency; Castration / methods; Cell Count / methods; Estradiol / pharmacology; Estrogens / pharmacology; Female; Gene Expression Regulation / drug effects; Gene Expression Regulation / genetics; Gene Expression Regulation / physiology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons / drug effects; Neurons / metabolism; Phytoestrogens / pharmacology; Receptors, Progesterone / genetics; Receptors, Progesterone / metabolism
TL;DR:
It is hypothesized that both aromatization of androgens to estrogens and dietary sources of additional estrogens are part of the normal requirement for sex differences in the rodent brain.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2009 journal article
A robust QTL mapping procedure
Journal of Statistical Planning and Inference, 139(3), 978–989.
author keywords: GEE; Generalized least squares estimate; Quantitative trait; Weighted least squares estimate; Wilcoxon-Mann-Whitney statistic
TL;DR:
This work generalizes the mapping problem to a genuine nonparametric setup and provides a robust estimation procedure for the situation where the underlying phenotype distributions are completely unspecified, in quantitative-trait linkage studies using experimental crosses.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2009 journal article
Replication and narrowing of gene expression quantitative trait loci using inbred mice
Mammalian Genome, 20(7), 437–446.
MeSH headings : Animals; Chromosome Mapping / methods; DNA Replication; Female; Gene Expression Profiling / methods; Linkage Disequilibrium; Male; Mice / classification; Mice / genetics; Mice, Inbred Strains; Phylogeny; Quantitative Trait Loci
TL;DR:
EQTL mapping in inbred strains is best carried out in combination with an eQTL linkage study, and the shorter linkage disequilibrium in the MDP strains allowed us to considerably narrow the locus and limit the number of candidate genes to a cluster of Serpin genes, which code for extracellular proteases.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2009 journal article
A susceptibility gene for type 2 diabetes confers substantial risk for diabetes complicating cystic fibrosis
Diabetologia, 52(9), 1858–1865.
author keywords: Association; CFRD; Corticosteroid; Cystic fibrosis; Diabetes; Genetics; Glucocorticoid; Modifier gene; TCF7L2
TL;DR:
A genetic variant conferring risk for type 2 diabetes in the general population is a modifier of risk for diabetes in CF.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2009 journal article
Shrinkage and model selection with correlated variables via weighted fusion
Computational Statistics & Data Analysis, 53(4), 1284–1298.
TL;DR:
The weighted fusion can potentially incorporate information redundancy among correlated variables for estimation and variable selection and allows the selection of more than n variables in a motivated way when the number of predictors p is larger than thenumber of observations n.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2009 journal article
Light activated modulation of protein activity (Lamp): A tool for spatiotemporal control of signaling components in living embryos
Developmental Biology, 331(2), 482.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2009 journal article
Wnt/planar cell polarity signaling controls endoderm cell rearrangements during the morphogenesis of the primitive gut tube
Developmental Biology, 331(2), 450.
Source: Crossref
Added: August 28, 2020
2009 journal article
Small molecule-mediated “phenotypic engineering” reveals a role for retinoic acid in anuran gut evolution
Developmental Biology, 331(2), 400.
Source: Crossref
Added: August 28, 2020
2009 journal article
A comprehensive approach to haplotype-specific analysis by penalized likelihood
European Journal of Human Genetics, 18(1), 95–103.
MeSH headings : Computer Simulation; Haplotypes / genetics; Humans; Likelihood Functions; Models, Statistical; Quantitative Trait, Heritable
TL;DR:
Simulation studies reveal the better abilities of the proposed method to identify the haplotype effect structure compared with the traditional haplotype association methods, demonstrating the informativeness and powerfulness of the propose method.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
16. Peace, Justice and Strong Institutions
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2009 journal article
Role of vapBC toxin–antitoxin loci in the thermal stress response of Sulfolobus solfataricus
Biochemical Society Transactions, 37(1), 123–126.
author keywords: archaeon; heat shock; hyperthermophile; stress response; Sulfolobus solfataricus; toxin-antioxin locus
MeSH headings : Antitoxins / metabolism; Archaeal Proteins / genetics; Archaeal Proteins / metabolism; Genome, Archaeal / genetics; Heat-Shock Response; Stress, Physiological; Sulfolobus solfataricus / genetics; Sulfolobus solfataricus / metabolism; Temperature; Toxins, Biological / genetics; Toxins, Biological / metabolism
TL;DR:
Findings indicate that more work needs to be done to determine the role of VapBCs in S. solfataricus and other thermophilic archaea, especially with respect to post-transcriptional regulation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID
Added: August 28, 2020
2009 journal article
Tracking toxins
Nature Geoscience, 2(4), E5–E5.
Sources: Crossref, NC State University Libraries
Added: June 28, 2020
2009 journal article
Rapid downward transport of the neurotoxin domoic acid in coastal waters
Nature Geoscience, 2(4), 272–275.
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: June 28, 2020
2009 journal article
This land : Dune buggies
Natural History, 118(7), 38–39. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349765769&partnerID=MN8TOARS
Contributors: R. Dunn
Source: ORCID
Added: May 7, 2020
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