Works Published in 2012
Displaying works 121 - 140 of 613 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2012 journal article
Coalescent patterns for chromosomal inversions in divergent populations.
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 2.
author keywords: chromosomal inversions; coalescent models; local adaptation; recombination; genetic variation
MeSH headings : Adaptation, Biological; Alleles; Animals; Chromosome Inversion / genetics; Chromosomes / genetics; Computer Simulation; Evolution, Molecular; Genetic Drift; Genetic Speciation; Genetic Variation; Genetics, Population; Models, Genetic; Recombination, Genetic; Selection, Genetic
TL;DR:
It is found that ancient inversion polymorphisms cause genetic diversity to depart dramatically from neutral expectations, and coalescent models of neutral sites linked to an inversions polymorphism in two locally adapted populations provide the foundation for quantitative analyses of the roles that inversions have played in speciation.
(via Semantic Scholar)
rstb.royalsocietypublishing.org (publisher PDF)
Source: ORCID
Added: September 15, 2020
2012 journal article
REPRODUCTIVE ISOLATION AND LOCAL ADAPTATION QUANTIFIED FOR A CHROMOSOME INVERSION IN A MALARIA MOSQUITO
Evolution, 67(4), 946–958.
author keywords: Anopheles; assortative mating; selection; postzygotic; prezygotic; speciation
MeSH headings : Adaptation, Biological / genetics; Animal Migration; Animals; Anopheles / genetics; Cameroon; Chromosome Inversion; Chromosomes, Insect / genetics; Ecosystem; Evolution, Molecular; Genetic Speciation; Heterozygote; Homozygote; Models, Genetic; Population / genetics; Reproductive Isolation; Selection, Genetic
TL;DR:
The first estimates from any organism for the total amount of reproductive isolation associated with an inversion segregating in natural populations are provided, suggesting that this one inversion can generate most of the genetic barriers needed for speciation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: September 15, 2020
2012 journal article
Differentiation of programmed Arabidopsis cells
Bioengineered, 3(1), 54–59.
author keywords: Arabidopsis thaliana; anthocyanin; PAP1; metabolic; engineering; metabolic fate; plant secondary metabolism
MeSH headings : Anthocyanins / metabolism; Arabidopsis / cytology; Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Cell Differentiation / genetics; Cell Differentiation / physiology; Gene Expression Regulation, Plant; Pancreatitis-Associated Proteins; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR:
The potential mechanisms that underlie the programming and reprogramming of gene expression involved in anthocyanin biosynthesis are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: September 14, 2020
2012 journal article
Convergent and divergent evolution of metabolism in sulfur-oxidizing symbionts and the role of horizontal gene transfer
Current Opinion in Microbiology, 15(5), 621–631.
MeSH headings : Animals; Aquatic Organisms / microbiology; Aquatic Organisms / physiology; Bacteria / genetics; Bacteria / metabolism; Bacterial Physiological Phenomena; Evolution, Molecular; Gene Transfer, Horizontal; Genetic Variation; Genomics / methods; Invertebrates / microbiology; Invertebrates / physiology; Metabolic Networks and Pathways / genetics; Oxidation-Reduction; Phylogeny; RNA, Ribosomal, 16S / genetics; Sulfur Compounds / metabolism; Symbiosis
TL;DR:
It is hypothesize that horizontal gene transfer (HGT) would explain many of these incongruencies, and conclude that HGT may have played a significant role in shaping the metabolic evolution of GammaSOX symbionts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 12, 2020
2012 journal article
Genetic Structure of Clavibacter michiganensis subsp. michiganensis Populations in Michigan Commercial Tomato Fields
Plant Disease, 96(6), 788–796.
TL;DR:
The frequency of PCR types detected with BOX-PCR in all strains and Bayesian cluster analysis, pairwise differentiation index comparisons, and genetic diversity estimates of 96 strains genotyped for six virulence-related genes revealed that C. michiganensis populations in Michigan tomato fields are geographically structured.
(via Semantic Scholar)
Source: ORCID
Added: September 8, 2020
2012 journal article
The Genetic Structure of Pseudoperonospora cubensis Populations
Plant Disease, 96(10), 1459–1470.
TL;DR:
Although this study provides an initial map of global population structure of P. cubensis, future genotyping of isolates could reveal population structure within specific geographic regions, across a wider range of hosts, or during different time points during the growing season.
(via Semantic Scholar)
Source: ORCID
Added: September 8, 2020
2012 journal article
Advances in Research on Phytophthora capsici on Vegetable Crops in The United States
Plant Disease, 96(11), 1588–1600.
TL;DR:
Phytophthora capsici causes foliar blighting, damping-off, wilting, and root, stem, and fruit rot of susceptible hosts, and economic losses are experienced annually in vegetable crops including cucurbits and peppers.
(via Semantic Scholar)
Source: ORCID
Added: September 8, 2020
2012 journal article
Cooperative All-Or-None Recruitment of Synaptotagmin C2AB on Single Vesicles Explains Why Ca2+ Regulates the Amplitude of SNARE Mediated Vesicle Fusion
Biophysical Journal, 102(3), 318a–319a.
TL;DR:
It is demonstrated that this striking phenotype originates from the highly cooperative binding of syt to membranes that results to an all-or-none recruitment at the single vesicle level1-4 which is regulated by Ca2+.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Crossref, ORCID
Added: September 8, 2020
2012 journal article
Conformational Changes in MutS during Mismtach Repair Signaling Determined with Single Molecule FRET
Biophysical Journal, 102(3), 283a.
TL;DR:
It is found that DNA binding domains of MutS undergo large movements as it is converted to sliding clamp in a two step process, which results in a ring conformation that allows MutS to slide on DNA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Crossref, ORCID
Added: September 8, 2020
2012 journal article
Single Molecule FRET Studies of the DNA Mismatch Repair Protein MutSα using Specific Labeling with Unnatural Amino Acids
Biophysical Journal, 102(3), 282a.
TL;DR:
This work seeks to understand the mechanism behind the initiation step of mismatch repair in eukaryotes: binding of MutSα (Msh2 - Msh6) to mismatched DNA, and reports progress using unnatural amino acid labeling approaches.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID
Added: September 8, 2020
2012 chapter
Macromolecular Models by Single Molecule FRET
In NATO Science for Peace and Security Series B: Physics and Biophysics (pp. 1–19).
TL;DR:
Recent applications of single molecule FRET are discussed to obtain a model of the synaptotagmin-1:SNARE complex and to study the conformation of PSD-95.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 8, 2020
2012 journal article
Lethal ovitraps and dengue prevention: report from Iquitos, Peru
International Journal of Infectious Diseases, 16, e473.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: September 6, 2020
2012 chapter
Pheromone Production
In Insect Endocrinology (pp. 523–567).
TL;DR:
There is much better understanding of how pheromones are made, and in some systems the authors are developing an understanding of their regulation at the molecular level, and the continued application of the powerful tools of molecular biology along with studies using genomics and proteomics will only increase the rate at which researchers increase the understanding of phersomone production.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 5, 2020
2012 journal article
The Role of the Contractile Ring during Cytokinesis
Biophysical Journal, 102(3), 219a.
Source: Crossref
Added: August 28, 2020
2012 journal article
Molecular confirmation of Trichomonas gallinae and other parabasalids from Brazil using the 5.8S and ITS-1 rRNA regions
Veterinary Parasitology, 190(1-2), 36–42.
author keywords: Avian diseases; Brazil; Parabasalids; Trichomonas gallinae; Trichomonosis; Simplicomonas
MeSH headings : Animals; Base Sequence; Bird Diseases / parasitology; Bird Diseases / pathology; Birds; Brazil; DNA, Protozoan / chemistry; DNA, Protozoan / genetics; DNA, Ribosomal Spacer / chemistry; DNA, Ribosomal Spacer / genetics; Falconiformes / parasitology; Female; Genetic Variation; Genotype; Male; Molecular Sequence Data; Parabasalidea / genetics; Parabasalidea / isolation & purification; Passeriformes / parasitology; Phylogeny; Polymerase Chain Reaction; Protozoan Infections, Animal / parasitology; Protozoan Infections, Animal / pathology; RNA, Ribosomal / genetics; RNA, Ribosomal, 5.8S / genetics; Sequence Analysis, DNA; Strigiformes / parasitology; Trichomonas / genetics; Trichomonas / isolation & purification; Trichomonas Infections / parasitology; Trichomonas Infections / pathology; Trichomonas Infections / veterinary
TL;DR:
In the owls, the caseous material extended into the mandibular muscles and invaded the sinuses of the skull, and Organisms similar to those described above also were found in the liver of the two green-winged saltators, the first report of trichomonosis in a striped owl and a toco toucan.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2012 journal article
The digestive neuronal–glial–epithelial unit: a new actor in gut health and disease
Nature Reviews Gastroenterology & Hepatology, 10(2), 90–100.
MeSH headings : Animals; Cell Membrane Permeability / physiology; Cell Proliferation; Enteric Nervous System / cytology; Enteric Nervous System / physiology; Gastrointestinal Diseases / pathology; Gastrointestinal Diseases / physiopathology; Gastrointestinal Tract / cytology; Gastrointestinal Tract / physiology; Homeostasis / physiology; Humans; Intestinal Mucosa / cytology; Intestinal Mucosa / physiology; Neuroglia / cytology; Neuroglia / physiology; Neurons / cytology; Neurons / physiology; Wound Healing / physiology
TL;DR:
Findings demonstrating that the ENS is a key regulator of IEB function and is actively involved in pathologies associated with altered barrier function are summarized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2012 journal article
Influence of Nanoscale Particle Roughness on the Stability of Pickering Emulsions
Langmuir, 28(33), 12038–12043.
Contributors: A. San-Miguel * & S. Behrens *
TL;DR:
A surface treatment is developed, applicable to micrometer-sized particles and macroscopic surfaces alike, that produces surface coatings with finely tunable nanoscale roughness and identical surface chemistry that correlated with the stability of emulsions prepared with coated particles of different roughness.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 28, 2020
2012 journal article
Soft microenvironments promote the early neurogenic differentiation but not self-renewal of human pluripotent stem cells
Integrative Biology, 4(9), 1049–1058.
MeSH headings : Cell Culture Techniques / methods; Cell Differentiation / physiology; Dopaminergic Neurons / cytology; Extracellular Matrix / physiology; Flow Cytometry; Humans; Microscopy, Atomic Force; Microscopy, Phase-Contrast; Neurogenesis / physiology; Pluripotent Stem Cells / cytology; Stress, Mechanical
TL;DR:
It is found that increasing extracellular matrix stiffness in vitro increases hPSC cell and colony spread area but does not alter self-renewal, in contrast to past studies with mESCs, and softer ECMs with stiffnesses similar to that of neural tissue promote the generation of early neural ectoderm.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2012 journal article
A Genetic Strategy for the Dynamic and Graded Control of Cell Mechanics, Motility, and Matrix Remodeling
Biophysical Journal, 102(3), 434–442.
MeSH headings : Biomechanical Phenomena; Cell Line; Cell Movement / drug effects; Cell Movement / genetics; Collagen / metabolism; Extracellular Matrix / drug effects; Extracellular Matrix / genetics; Extracellular Matrix / metabolism; Gene Expression Regulation / drug effects; Gene Expression Regulation / genetics; Genetic Engineering / methods; Humans; Mechanical Phenomena; Mechanotransduction, Cellular / drug effects; Mechanotransduction, Cellular / genetics; Mutation; Promoter Regions, Genetic / genetics; Tetracycline / pharmacology
TL;DR:
It is demonstrated that soft ECMs render cells maximally sensitive to changes in RhoA activity, and that by modulating the ability of cells to engage and contract soft ECM, the strategy enables the physical interactions between cells and the ECM and thereby dictate how cells respond to matrix properties.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2012 journal article
Experience-facilitated improvements in pup retrieval; evidence for an epigenetic effect
Hormones and Behavior, 62(2), 128–135.
author keywords: Maternal experience; Epigenetics; Sodium butyrate; HDAC inhibition; Oxytocin; CBP
MeSH headings : Animals; Animals, Newborn; Behavior, Animal / drug effects; Behavior, Animal / physiology; Butyrates / pharmacology; Epigenesis, Genetic / drug effects; Epigenesis, Genetic / physiology; Exploratory Behavior / drug effects; Exploratory Behavior / physiology; Female; Gene Expression Regulation / drug effects; Gene Expression Regulation / physiology; Histone Deacetylase Inhibitors / pharmacology; Learning / drug effects; Learning / physiology; Maternal Behavior / drug effects; Maternal Behavior / physiology; Mice; Mice, Inbred C57BL; Pregnancy
TL;DR:
Experiences with infants suggest that experience induces high levels of maternal care via epigenetic modifications, which in turn change expression of genes that promote maternal care.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
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