Works Published in 2013
Displaying works 121 - 140 of 660 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2013 journal article
3-(2,6-difluorobenzamido)-5-(4-ethoxyphenyl) thiophene-2-carboxylic acid inhibits E.coli UT189 bacterial capsule biogenesis
https://www.ncbi.nlm.nih.gov/books/NBK143534
Source: ORCID
Added: December 30, 2020
2013 journal article
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Nature Genetics, 45(9), 984–994.
MeSH headings : Adult; Attention Deficit Disorder with Hyperactivity / genetics; Bipolar Disorder / genetics; Child; Child Development Disorders, Pervasive / genetics; Crohn Disease / genetics; Depressive Disorder, Major / genetics; Genetic Heterogeneity; Genetic Predisposition to Disease; Genome, Human; Genome-Wide Association Study; Humans; Inheritance Patterns; Mental Disorders / genetics; Polymorphism, Single Nucleotide; Schizophrenia / genetics
TL;DR:
Empirical evidence of shared genetic etiology for psychiatric disorders can inform nosology and encourages the investigation of common pathophysiologies for related disorders.
(via Semantic Scholar)
espace.library.uq.edu.au (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: December 29, 2020
2013 chapter
Reprogramming the Biosynthesis of Natural Products by Directed Evolution
In A. Kantardjieff, P. Asuri, J. L. Coffman, & K. Jayapal (Eds.), Developments in Biotechnology and Bioprocessing (pp. 147–163).
Ed(s): A. Kantardjieff, P. Asuri, J. Coffman & K. Jayapal
Sources: Crossref, ORCID
Added: December 22, 2020
2013 journal article
Single Nucleotide Polymorphism (SNP) Detection and Genotype Calling from Massively Parallel Sequencing (MPS) Data
Statistics in Biosciences, 5(1), 3–25.
author keywords: Massively parallel sequencing; Next-generationsequencing; SNP detection; Genotype calling; Linkage disequilibrium (LD)
TL;DR:
A review of statistical methods proposed in the past five years to detect SNPs and call genotypes at the detected polymorphic sites from the sequencing data, and discusses emerging issues and future directions related to SNP detection and genotype calling from MPS data.
(via Semantic Scholar)
Source: Crossref
Added: December 21, 2020
2013 journal article
UDP-glucose Dehydrogenase Activity and Optimal Downstream Cellular Function Require Dynamic Reorganization at the Dimer-Dimer Subunit Interfaces
Journal of Biological Chemistry, 288(49), 35049–35057.
author keywords: Dehydrogenase; Enzyme Catalysis; Glycobiology; Hyaluronate; Prostate Cancer; Protein Conformation; Protein Dynamics; Cardiac Defects; Human UGDH; Hyaluronan
MeSH headings : Amino Acid Substitution; Enzyme Stability; HEK293 Cells; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Structure, Quaternary; Protein Subunits; Proteolysis; Thermodynamics; Uridine Diphosphate Glucose Dehydrogenase / chemistry; Uridine Diphosphate Glucose Dehydrogenase / genetics; Uridine Diphosphate Glucose Dehydrogenase / metabolism
TL;DR:
Comparison of kinetic and thermal stability parameters revealed structurally dependent properties consistent with a role for controlled assembly and disassembly of the hexamer in the regulation of UGDH, which support a model that requires an operational dimer-hexamer equilibrium to function efficiently and preserve regulated activity in the cell.
(via Semantic Scholar)
Source: Crossref
Added: December 21, 2020
2013 journal article
Characterization of IRDye 800CW chlorotoxin as a targeting agent for brain tumors
Analytical Biochemistry, 440(2), 212–219.
author keywords: Medulloblastoma; IRDye 800CW; Chlorotoxin; In vivo imaging; Blood-brain barrier; ND2:SmoA1 homozygous transgenic mouse
MeSH headings : Animals; Benzenesulfonates / chemistry; Blood-Brain Barrier / metabolism; Cell Line, Tumor; Cerebellar Neoplasms / diagnosis; Cerebellar Neoplasms / metabolism; Cerebellar Neoplasms / pathology; Humans; Indoles / chemistry; Matrix Metalloproteinase 2 / metabolism; Medulloblastoma / diagnosis; Medulloblastoma / metabolism; Medulloblastoma / pathology; Mice; Scorpion Venoms / chemistry; Scorpion Venoms / metabolism
TL;DR:
Because increased vascular permeability was observed early in the disease model, larger dye-labeled imaging agents that exceed current BBB size restrictions may warrant renewed consideration as candidates for tumor detection and surgical resection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: December 21, 2020
2013 journal article
A generalized approach for measuring microcapsule permeability with Fluorescence Recovery After Photobleaching
Journal of Materials Science, 48(5), 2215–2223.
Contributors: J. Scrimgeour *, A. San-Miguel *, J. Curtis* & S. Behrens *
TL;DR:
The modified approach eliminates the need for painstaking controls to determine the FRAP measurement volume and the spatial distribution of bleached tracers, while accurately extracting the permeability of the microcapsule from FRAP data acquired using a straightforward procedure.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 11, 2020
2013 journal article
Confirming quantitative trait loci for aflatoxin resistance from Mp313E in different genetic backgrounds
Molecular Breeding, 32(1), 15–26.
Contributors: M. Willcox*, G. Davis*, M. Warburton, G. Windham, H. Abbas *, J. Betrán, J. Holland* , W. Williams
author keywords: Aspergillus flavus; Aflatoxin; Quantitative trait loci; Maize (Zea mays L.); Host plant resistance; Molecular markers; Genetic background
TL;DR:
Many of the quantitative trait loci (QTL) conferring resistance to aflatoxin accumulation from resistant maize donor Mp313E in a background of the susceptible inbred line Va35 are stable over the environments and genetic backgrounds tested, which will make them more valuable in breeding efforts.
(via Semantic Scholar)
Source: ORCID
Added: December 8, 2020
2013 journal article
Micropropagation and Polyploid Induction of Acer platanoides 'Crimson Sentry'
Journal of Environmental Horticulture, 31(4), 246–252.
TL;DR:
Protocols were developed for micropropagation and induction of autopolyploids in a fastigiate cultivar of Norway maple and optimal in vitro rooting was achieved with 10 μM indole-3-butyric acid.
(via Semantic Scholar)
Sources: NC State University Libraries, ORCID
Added: December 4, 2020
2013 journal article
Corrigendum to “Molecular confirmation of Trichomonas gallinae and other parabasalids from Brazil using the 5.8S and ITS-1 rRNA regions” [Vet. Parasitol. 190 (1–2) (2012) 36–42]
Veterinary Parasitology, 196(3-4), 552.
TL;DR:
This dissertation aims to provide a history of wildlife medicine and practices in Minas Gerais from 1989 to 2002, a period chosen in order to explore its roots as well as specific cases up to and including the year in which Cecil the lion was shot.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: Crossref
Added: November 16, 2020
2013 chapter
Cardiomyopathy in the boxer dog
In Current Veterinary Therapy (Small Animal Practice) XV. Philadelphia: WB Saunders.
Source: NC State University Libraries
Added: October 10, 2020
2013 journal article
A sequential coalescent algorithm for chromosomal inversions.
Heredity, 9.
author keywords: inversions; coalescent; simulation; recombination; linkage disequilibrium; ancestral recombination graph
MeSH headings : Algorithms; Chromosome Inversion; Computer Simulation; Genetics, Population; Linkage Disequilibrium; Models, Genetic; Recombination, Genetic
TL;DR:
The SMC algorithm is fast, memory-efficient and accurate, making it feasible to simulate large inversions in large populations for the first time, and enables studies of patterns of genetic variation and tests of hypotheses that were previously intractable.
(via Semantic Scholar)
Source: ORCID
Added: September 15, 2020
2013 journal article
Characterization of Flavan-3-ols and Expression of MYB and Late Pathway Genes Involved in Proanthocyanidin Biosynthesis in Foliage of Vitis bellula
Metabolites, 3(1), 185–203.
author keywords: Vitis bellula; proanthocyanidins; anthocyanidin reductase; leucoanthocyanidin reductase; flavan-3-ols
TL;DR:
PA formation and characterization of gene expression involved in PA biosynthesis in leaves of V. bellula are reported and it is shown that both ANR and LAR branches are involved in PAs biosynthetic processes of this wild edible grape species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID
Added: September 13, 2020
2013 journal article
Improvement of the Oryza sativa Nipponbare reference genome using next generation sequence and optical map data
Rice, 6(1), 4.
author keywords: Oryza sativa; Nipponbare; Unified rice reference genome; Pseudomolecules; Minimum tiling path; Optical mapping; Genome re-sequencing; Next-generation sequencing
TL;DR:
A revised, error-corrected, and validated assembly of the Nipponbare cultivar of rice was generated using optical map data, re-sequencing data, and manual curation that will facilitate on-going and future research in rice.
(via Semantic Scholar)
Source: ORCID
Added: September 8, 2020
2013 journal article
Dynamics of DNA Mismatch Repair Initiation Complex Revealed by Single Molecule Fluorescence
Biophysical Journal, 104(2), 368a.
TL;DR:
Single molecule fluorescence resonance energy transfer (smFRET) is used to characterize conformational changes in this ternary complex through the process of mismatch recognition, MutS-MutL interaction and large MutS and MutL assembly formation on DNA and found that the sliding clamp formation of MutS is inhibited by MutL interaction.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 8, 2020
2013 journal article
Retraction Note to: A reexamination of molecular markers for use in marker-assisted breeding in tomato
Euphytica, 194(1), 149–149.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, ORCID
Added: September 8, 2020
2013 journal article
A method for detecting hidden additivity in two-factor unreplicated experiments
Computational Statistics & Data Analysis, 67, 95–104.
author keywords: Interaction effects; Latent variables; Non-additivity
TL;DR:
A multiplicity-adjusted all-configurations maximum interaction F (ACMIF) test to detect hidden additivity is developed and is illustrated using two data sets taken from the literature and a third taken from a recent study of copy number variation due to lymphoma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Crossref, ORCID
Added: September 5, 2020
2013 journal article
Enhancing microvascular formation and vessel maturation through temporal control over multiple pro-angiogenic and pro-maturation factors
Biomaterials, 34(36), 9201–9209.
author keywords: Controlled drug release; Angiogenesis; Growth factors; Drug delivery; Endothelial cell; Smooth muscle cell
MeSH headings : Angiogenesis Inducing Agents / pharmacology; Angiopoietin-1 / pharmacology; Angiopoietin-2 / pharmacology; Animals; Endothelium, Vascular / growth & development; Human Umbilical Vein Endothelial Cells / drug effects; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Mice; Mice, Inbred C57BL; Microvessels / drug effects; Microvessels / growth & development; Neovascularization, Physiologic / drug effects; Pericytes / drug effects; Pericytes / metabolism; Platelet Endothelial Cell Adhesion Molecule-1 / metabolism; Platelet-Derived Growth Factor / pharmacology; Time Factors; Vascular Endothelial Growth Factor A / pharmacology
TL;DR:
The results demonstrate the importance of temporal control over signaling in promoting vascular growth, vessel maturation and vascular remodeling as well as creating tissue engineered constructs and therapies aimed at promoting healing after acute wounds and in chronic conditions such as diabetic ulcers and peripheral artery disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID
Added: August 28, 2020
2013 journal article
Pan-neuronal maturation but not neuronal subtype differentiation of adult neural stem cells is mechanosensitive
Scientific Reports, 3(1).
MeSH headings : Adult Stem Cells / cytology; Adult Stem Cells / metabolism; Animals; Brain / metabolism; Cell Differentiation / physiology; Cell Lineage; Cellular Microenvironment / physiology; Female; Gene Expression; Gene Expression Regulation, Developmental; Neural Stem Cells / cytology; Neural Stem Cells / metabolism; Neurons / classification; Neurons / cytology; Neurons / metabolism; Rats; Time Factors; Tubulin / genetics
TL;DR:
C cultured adult neural stem cells on variable stiffness ECMs under conditions that promote neuronal fate commitment for extended time periods suggest that a wide range of stiffnesses fully permit pan-neuronal NSC differentiation, that an intermediate stiffness optimizes expression of pan-Neuronal genes and that stiffness does not impact commitment to particular neuronal subtypes.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2013 journal article
Norditerpene alkaloid concentrations in tissues and floral rewards of larkspurs and impacts on pollinators
Biochemical Systematics and Ecology, 48, 123–131.
author keywords: Larkspur; Delphinium; Norditerpene alkaloids; Plant parts; Pollen; Nectar
TL;DR:
It is suggested that nectar with low alkaloid concentrations may be beneficial to plant fitness by limiting adverse effects on pollinator activity and optimal defense theory.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
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