Works Published in 2006
Displaying works 141 - 160 of 364 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2006 journal article
The Comparative Toxicogenomics Database (CTD): a resource for comparative toxicological studies
Journal of Experimental Zoology Part A: Comparative Experimental Biology, 305A(9), 689–692.
MeSH headings : Animals; Databases, Factual; Humans; Toxicogenetics; Xenobiotics / toxicity
TL;DR:
The publicly available Comparative Toxicogenomics Database (CTD) is developed to promote understanding about the effects of environmental chemicals on human health and identifies interactions between chemicals and genes and facilitates cross-species comparative studies of these genes.
(via Semantic Scholar)
europepmc.org (repository)
Sources: Crossref, NC State University Libraries
Added: August 10, 2019
2006 journal article
Optimized Transduction of Canine Paediatric CD34+ Cells Using an MSCV-based Bicistronic Vector
Veterinary Research Communications, 30(8), 881–901.
author keywords: XSCID; CD34(+); retroviral transduction; amphotropic retrovirus; gamma c
MeSH headings : Animals; Antigens, CD34 / metabolism; Bone Marrow Cells / metabolism; Cell Line; Dogs; Fibroblasts; Genes / genetics; Genetic Vectors / genetics; Mice; Retroviridae / genetics; Stem Cells / virology; Thymus Gland / cytology; Transduction, Genetic / methods; Transduction, Genetic / veterinary
TL;DR:
A murine MSCV-based bicistronic Retroviral vector, containing the common gamma chain (γc) and enhanced green fluorescent protein (EGFP) cDNAs, is used to optimize retroviral transduction of canine cells, including an adherent canine thymus fibroblast cell line, Cf2Th, as well as normal canine CD34+ bone marrow (BM) cells.
(via Semantic Scholar)
Source: Crossref
Added: July 27, 2019
2006 other
Infection dynamics on small-world networks
Sources: Crossref, ORCID
Added: July 20, 2019
2006 chapter
Drug resistance in acute viral infections: Rhinovirus as a case study
In Disease Evolution (pp. 193–212).
TL;DR:
It is seen that an efficient immune response can reduce the likelihood of the emergence of resistant virus, and resistance poses more of a problem for chronic infections in which there is significant immune impairment than for acute infections.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID
Added: July 20, 2019
2006 journal article
The role of neuregulin-ErbB4 interactions on the proliferation and organization of cells in the subventricular zone
Proceedings of the National Academy of Sciences, 103(6), 1930–1935.
author keywords: adult neurogenesis; rostral migratory stream; schizophrenia
MeSH headings : Animals; Cell Differentiation; Cell Movement; Cell Proliferation; Enzyme Activation; ErbB Receptors / deficiency; ErbB Receptors / genetics; ErbB Receptors / metabolism; Ligands; Mice; Neuregulins / metabolism; Olfactory Bulb / cytology; Olfactory Bulb / metabolism; Prosencephalon / cytology; Prosencephalon / metabolism; Protein Binding; Receptor, ErbB-4; Time Factors
TL;DR:
NRG2 is identified as a factor capable of promoting SVZ proliferation, leading to the formation of new neurons in vivo, indicating that different NRG ligands affect distinct populations of differentiating neural precursors in the neurogenic regions of the mature forebrain.
(via Semantic Scholar)
Source: Crossref
Added: July 20, 2019
2006 journal article
Diversity Analysis of Garlic (Allium sativum L.) Germplasms Available in Nepal Based on Morphological Characters
Genetic Resources and Crop Evolution, 53(1), 205–212.
author keywords: Allium; cluster analysis; garlic; genetic diversity; PCA
TL;DR:
The level of variation found in the collection showed the great potentiality of improving agronomic characters in garlic, with four principal components explaining more than 86% of total variation.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: June 6, 2019
2006 journal article
Genomic Regions Associated with Amino Acid Composition in Soybean
Molecular Breeding, 17(1), 79–89.
author keywords: amino acid; genomic regions; Glycine max; lysine; QTL mapping; soybean; threonine; tryptophan
TL;DR:
QTL detected for amino acids in soybean in this experiment are expected to be useful for future breeding programs targeting development of improved soybean amino acid composition for human and animal nutrition.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: June 6, 2019
2006 journal article
Registration of Soybean Germplasm Lines TN03–350 and TN04–5321 with Improved Protein Concentration and Quality
Crop Science, 46(5), 2328.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: June 6, 2019
2006 journal article
Modifier QTL for fatty acid composition in soybean oil
Euphytica, 152(1), 67–73.
author keywords: Glycine max; molecular markers; SSR
TL;DR:
The lack of markers associated with multiple fatty acids suggests the possibility of independently changing fatty acid levels to achieve a desirable composition, except for regions common to all saturated fatty acids.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: June 6, 2019
2006 journal article
Visual analysis of statistical results from microarray studies of human breast cancer.
Oncology Reports, c, 1043–1047. http://europepmc.org/abstract/med/16525698
Source: ORCID
Added: May 14, 2019
2006 article
Integrated analysis of genetic and proteomic data.
http://europepmc.org/theses/ETH/7299
Source: ORCID
Added: May 14, 2019
2006 journal article
Visual analysis of statistical results from microarray studies of human breast cancer
Oncol Rep, 4(4), 1043–1047.
Contributors: D. Reif* & J. Moore
MeSH headings : Antineoplastic Agents / therapeutic use; Breast Neoplasms / drug therapy; Breast Neoplasms / genetics; Data Interpretation, Statistical; Databases, Genetic; Female; Gene Expression Profiling; Humans; Oligonucleotide Array Sequence Analysis; Software
TL;DR:
Using a publicly available microarray dataset of gene expression response to chemotherapeutic agents in human breast cancer cell lines, it is demonstrated the usefulness of the EVA system for interpreting statistical results.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2006 conference paper
Understanding the evolutionary process of grammatical evolution neural networks for feature selection in genetic epidemiology
Proceedings of the 2006 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB'06, 263–270.
Contributors: A. Motsinger*, D. Reif* , S. Dudek * & M. Ritchie *
TL;DR:
The evolutionary characteristics of GENN are compared to that of a random search neural network strategy to better understand the benefits provided by the evolutionary learning process - including advantages with respect to chromosome size and the representation of functional versus non-functional features within the models generated by the two approaches.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: May 14, 2019
2006 journal article
Machine Learning for Detecting Gene-Gene Interactions
Applied Bioinformatics, 5(2), 77â88.
Contributors: B. McKinney *, D. Reif* , M. Ritchie* & J. Moore *
MeSH headings : Algorithms; Animals; Artificial Intelligence; Genome, Human; Genomics / methods; Genotype; Humans; Models, Genetic; Models, Statistical; Neural Networks, Computer; Polymorphism, Single Nucleotide
TL;DR:
This review discusses machine-learning models and algorithms for identifying and characterising susceptibility genes in common, complex, multifactorial human diseases and focuses on the following machine- learning methods that have been used to detect gene-gene interactions: neural networks, cellular automata, random forests, and multifactor dimensionality reduction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: May 14, 2019
2006 conference paper
Feature selection using a random forests classifier for the integrated analysis of multiple data types
Proceedings of the 2006 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB'06, 171–178.
Contributors: D. Reif* , A. Motsinger*, B. McKinney *, J. Crowe Jr. & J. Moore
TL;DR:
The results indicate that utilizing multiple data types is beneficial when the disease model is complex and the phenotypic outcome-associated data type is unknown, and RF is adept at identifying relevant features in high-dimensional data with small main effects and low heritability.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: May 14, 2019
2006 journal article
Cytokine expression patterns associated with systemic adverse events following smallpox immunization.
Journal of Infectious Diseases, 194(4), 444–453.
Contributors: B. McKinney *, D. Reif* , M. Rock*, K. Edwards *, S. Kingsmore *, J. Moore, J. Crowe Jr.
MeSH headings : Adolescent; Adult; Chemokine CCL11; Chemokines, CC / blood; Chemokines, CC / immunology; Cytokines / blood; Cytokines / immunology; Decision Trees; Female; Granulocyte Colony-Stimulating Factor / blood; Granulocyte Colony-Stimulating Factor / immunology; Humans; Intercellular Adhesion Molecule-1 / blood; Intercellular Adhesion Molecule-1 / immunology; Male; Skin Diseases, Vesiculobullous / chemically induced; Skin Diseases, Vesiculobullous / pathology; Skin Diseases, Vesiculobullous / prevention & control; Smallpox / prevention & control; Smallpox Vaccine / adverse effects; Tissue Inhibitor of Metalloproteinase-2 / blood; Tissue Inhibitor of Metalloproteinase-2 / immunology; Vaccinia virus / immunology
TL;DR:
This cytokine signature is characteristic of particular inflammatory response pathways and suggests that the secretion of cytokines by fibroblasts plays a central role in systemic adverse events.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2006 journal article
In situ methods to localize transgenes and transcripts in interphase nuclei: a tool for transgenic plant research
Plant Methods, 2, 18.
TL;DR:
In situ methods to visualize transgenes and their transcripts during interphase from different tissues and plant species are developed, which reduce the time necessary for characterization of transgene integration by eliminating the need for time-consuming segregation analysis, and extend characterization to the interphase nucleus, thus increasing the likelihood of accurate prediction of transGene activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: April 21, 2019
2006 journal article
PATTERNS OF HABITAT USE BY PRIMATES IN EASTERN ECUADOR
Theses, 41, 146. https://irl.umsl.edu/thesis/41
Source: NC State University Libraries
Added: February 26, 2019
2006 journal article
Evaluating phylogenetic patterns of threat in Bignonieae (Bignoniaceae) using herbarium data
Abstracts - Poster. https://bdpi.usp.br/item/002696357
Source: NC State University Libraries
Added: February 26, 2019
2006 speech
Influence of an introgressed N. tomentosa QTL on leaf number and correlated traits in N. tabacum L.
Lewis, R. S., Milla, S. R., & Kernodle, S. P. (2006, November). Presented at the Proceedings of the American Agronomy International Annual Meeting, Indianapolis, IN.
Event: Proceedings of the American Agronomy International Annual Meeting at Indianapolis, IN
Source: NC State University Libraries
Added: February 23, 2019
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