Works Published in 2008
Displaying works 161 - 180 of 473 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2008 journal article
Evaluation of the flanking nucleotide sequences of sarcomeric hypertrophic cardiomyopathy substitution mutations
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 642(1-2), 86–89.
author keywords: hypertrophic cardiomyopathy; mutation; methylation; deamination
MeSH headings : Amino Acid Substitution; Base Sequence; Cardiomyopathy, Hypertrophic / genetics; DNA Methylation; Humans; Mutation; Sarcomeres / genetics
TL;DR:
The large number of G to A and C to T mutations as well as the relative mutability of CG may suggest that deamination of methylated CpG is an important mechanism for mutation development in at least some of these cardiac genes.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: December 16, 2019
2008 journal article
Prevalence of the Myosin-Binding Protein C Mutation in Maine Coon Cats
Journal of Veterinary Internal Medicine, 22(4), 893–896.
author keywords: hypertrophic cardiomyopathy; genetics; MYBC3
MeSH headings : Animals; Cardiomyopathy, Hypertrophic / epidemiology; Cardiomyopathy, Hypertrophic / genetics; Cardiomyopathy, Hypertrophic / veterinary; Carrier Proteins / genetics; Cat Diseases / epidemiology; Cat Diseases / genetics; Cats; Female; Genetic Predisposition to Disease; Male; Prevalence
TL;DR:
Because of the high prevalence of this mutation, a breeding recommendation to eliminate all cats with the mutation could have a substantial impact on the gene pool, and additional studies are indicated to explore the relationship between genotype and clinical outcome in affected cats.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 16, 2019
2008 journal article
Breed distribution of the ABCB1-1Δ (multidrug sensitivity) polymorphism among dogs undergoing ABCB1 genotyping
Journal of the American Veterinary Medical Association, 233(6), 921–924.
MeSH headings : ATP Binding Cassette Transporter, Subfamily B, Member 1 / genetics; Alleles; Animals; Breeding; Cross-Sectional Studies; Dog Diseases / chemically induced; Dog Diseases / drug therapy; Dog Diseases / genetics; Dogs / genetics; Drug Resistance, Multiple / genetics; Female; Gene Deletion; Gene Frequency; Genes, MDR / genetics; Genotype; Male; Polymorphism, Genetic; Veterinary Drugs / adverse effects
TL;DR:
The ABCB1-1Delta polymorphism is associated with increased susceptibility to many adverse drug reactions and with suppression of the hypothalamic-pituitary-adrenal axis and is present in many herding breeds of dog.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 16, 2019
2008 journal article
Molecular evaluation of five cardiac genes in Doberman Pinschers with dilated cardiomyopathy
American Journal of Veterinary Research, 69(8), 1050–1053.
MeSH headings : Animals; Cardiomyopathy, Dilated / genetics; Cardiomyopathy, Dilated / veterinary; Dog Diseases / genetics; Dogs; Exons; Heart / physiopathology; Lamin Type A / genetics; Lamins / genetics; Myosin Heavy Chains / genetics; Troponin C / genetics; Troponin T / genetics
Sources: Crossref, ORCID
Added: December 16, 2019
2008 journal article
An index of myocardial performance applied to the right ventricle of Boxers with arrhythmogenic right ventricular cardiomyopathy
American Journal of Veterinary Research, 69(8), 1029–1033.
MeSH headings : Animals; Arrhythmias, Cardiac / physiopathology; Arrhythmias, Cardiac / veterinary; Cardiomyopathies / physiopathology; Cardiomyopathies / veterinary; Dog Diseases / physiopathology; Dogs; Heart Function Tests / veterinary; Ventricular Dysfunction, Right / physiopathology; Ventricular Dysfunction, Right / veterinary; Ventricular Function, Right / physiology
TL;DR:
Right ventricular dysfunction does not develop in Boxers with ARVC, suggesting that a more severe phenotype of the disease may be necessary for detection of dysfunction or that additional studies that use more sensitive techniques to evaluate myocardial function may be warranted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID
Added: December 11, 2019
2008 journal article
Formation of metal-nicotianamine complexes as affected by pH, ligand exchange with citrate and metal exchange. A study by electrospray ionization time-of-flight mass spectrometry
Rapid Communications in Mass Spectrometry, 22(10), 1553–1562.
Contributors: R. Rellan-Alvarez*
MeSH headings : Azetidinecarboxylic Acid / analogs & derivatives; Azetidinecarboxylic Acid / chemistry; Citric Acid / chemistry; Hydrogen-Ion Concentration; Metals / chemistry; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR:
Results support that NA may be the ligand chelating Fe at pH values usually found in phloem sap, whereas in the xylem sap NA is not likely to be involved in Fe transport, conversely to what occurs with other metals such as Cu and Ni.
(via Semantic Scholar)
hdl.handle.net (repository)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: November 15, 2019
2008 journal article
Cell Division Requires a Direct Link between Microtubule-Bound RacGAP and Anillin in the Contractile Ring
Current Biology, 18(1), 25–29.
MeSH headings : Actomyosin / metabolism; Animals; Cell Division / physiology; Contractile Proteins / analysis; Contractile Proteins / metabolism; Contractile Proteins / physiology; Drosophila / cytology; Drosophila / metabolism; Drosophila Proteins / analysis; Drosophila Proteins / metabolism; Drosophila Proteins / physiology; Fluorescence Resonance Energy Transfer; GTPase-Activating Proteins / analysis; GTPase-Activating Proteins / metabolism; GTPase-Activating Proteins / physiology; Microtubules / metabolism; Protein Interaction Mapping; Spindle Apparatus / metabolism
TL;DR:
The spindle-associated component, RacGAP50C, which specifies the site of cleavage, interacts directly with Anillin, an actin and myosin binding protein found in the contractile ring, and these results account for the long-observed dependence of cytokinesis on the continual presence of microtubules at the cortex.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: November 11, 2019
2008 journal article
Identification of quantitative trait loci for resistance to southern leaf blight and days to anthesis in two maize recombinant inbred line populations
Phytopathology, 98(3), 315–320.
Contributors: P. Balint-Kurti* , J. Zwonitzer, M. Pè, G. Pea, M. Lee & A. Cardinal
MeSH headings : Ascomycota / physiology; Breeding; Flowers / genetics; Flowers / growth & development; Flowers / microbiology; Host-Pathogen Interactions; Immunity, Innate / genetics; Plant Diseases / genetics; Plant Diseases / microbiology; Plant Leaves / genetics; Plant Leaves / growth & development; Plant Leaves / microbiology; Quantitative Trait Loci / genetics; Recombination, Genetic; Time Factors; Zea mays / genetics; Zea mays / growth & development; Zea mays / microbiology
TL;DR:
A comparison of the results of all published SLB resistance QTL studies suggested that bins 3.04 and 6.01 are 'hotspots' for SLB resistant loci, while there was any phenotypic correlation between the traits.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: ORCID
Added: October 23, 2019
2008 journal article
IDENTIFYING MAIZE GERMPLASM WITH RESISTANCE TO AFLATOXIN ACCUMULATION
Toxin Reviews, 27(3-4), 319–345.
author keywords: aflatoxin; Aspergillus flavus; maize; plant resistance; Zea mays
TL;DR:
USDA-ARS scientists at Mississippi State, Mississippi; Tifton, Georgia; and Raleigh, North Carolina; have engaged in a multilocation approach to germplasm screening, finding lines that displayed low levels of contamination should be useful in maize breeding programs for developing parental inbred lines and aflatoxin-resistant maize hybrids.
(via Semantic Scholar)
Source: ORCID
Added: October 23, 2019
2008 journal article
Mining and Harnessing Natural Variation: A Little MAGIC
Crop Science, 48(6), 2066.
Contributors: G. Johal *, P. Balint-Kurti n & C. Weil *
TL;DR:
A gene-centered approach is proposed, dubbed MAGIC (mutant-assisted gene identifi cation and characterization), that uses Mendelian mutants or other genetic variants in a trait of interest as reporters to identify novel genes and variants for that trait.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: ORCID
Added: October 23, 2019
2008 journal article
Arabidopsis LEAFY COTYLEDON2 induces maturation traits and auxin activity: Implications for somatic embryogenesis
Proceedings of the National Academy of Sciences, 105(8), 3151–3156.
author keywords: seed development; totipotency
TL;DR:
LEC2 causes rapid changes in auxin responses and induces cellular differentiation characteristic of the maturation phase of embryogenesis, and the relevance of these changes to the ability of LEC2 to promote somatic embryogenesis is discussed.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Cellular Programming of Plant Gene Imprinting
Cell, 132(5), 735–744.
MeSH headings : Animals; Epigenesis, Genetic; Gene Expression Regulation, Plant; Genes, Plant; Genomic Imprinting; Histone Code; Magnoliopsida / cytology; Magnoliopsida / genetics; Magnoliopsida / physiology
TL;DR:
Gene imprinting, the differential expression of maternal and paternal alleles, independently evolved in mammals and in flowering plants to prevent parthenogenetic development of the endosperm.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Increased glycolytic flux as an outcome of whole-genome duplication in yeast (Molecular Systems Biology (2007) 3 (129) DOI: 10.1038/msb4100170)
Molecular Systems Biology, 4.
Contributors: G. Conant* & K. Wolfe
Source: ORCID
Added: September 12, 2019
2008 journal article
Probabilistic cross-species inference of orthologous genomic regions created by whole-genome duplication in yeast
Genetics, 179(3), 1681–1692.
Contributors: G. Conant* & K. Wolfe *
MeSH headings : Candida glabrata / genetics; Gene Duplication; Genes, Fungal; Genome, Fungal / genetics; Models, Genetic; Phylogeny; Saccharomyces cerevisiae / genetics; Sequence Homology, Nucleic Acid; Species Specificity; Time Factors; Yeasts / genetics
TL;DR:
It is suggested that while duplicate copies of some genes may be lost neutrally after WGD, another set of genes May be initially preserved in duplicate by natural selection for reasons including dosage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: September 12, 2019
2008 journal article
Turning a hobby into a job: How duplicated genes find new functions
Nature Reviews Genetics, 9(12), 938–950.
Contributors: G. Conant* & K. Wolfe *
MeSH headings : Animals; Galactokinase / genetics; Gene Dosage; Gene Duplication; Gene Expression; Genome; Humans; Mutation; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae Proteins / genetics; Selection, Genetic; Transcription Factors / genetics
TL;DR:
Genomic data suggest that different gene classes tend to be retained after single-gene and whole-genome duplications, and in many cases the 'new' function of one copy is a secondary property that was always present, but that has been co-opted to a primary role after the duplication.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2019
2008 journal article
GenomeVx: Simple web-based creation of editable circular chromosome maps
Bioinformatics, 24(6), 861–862.
Contributors: G. Conant* & K. Wolfe *
MeSH headings : Chromosome Mapping / methods; Computer Graphics; Documentation / methods; Internet; Software; User-Computer Interface; Word Processing / methods
TL;DR:
GenomeVx is a web-based tool for making editable, publication-quality, maps of mitochondrial and chloroplast genomes and of large plasmids that show the location of genes and chromosomal features as well as a position scale.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2019
2008 journal article
Incipient speciation within a subgenus of rockfish (Sebastosomus) provides evidence of recent radiations within an ancient species flock
Marine Biology, 154(4), 701–717.
TL;DR:
Evidence of ongoing speciation within the rockfish genus Sebastes is provided and stages of this process from incipient to distinct species are revealed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: September 11, 2019
2008 journal article
Fine scale dispersal in Banggai Cardinalfish, Pterapogon kauderni, a coral reef species lacking a pelagic larval phase
Marine Genomics, 1(3-4), 129–134.
author keywords: Pterapogon kauderni; Banggai Cardinalfish; Marine dispersal; Microsatellites
TL;DR:
The Banggai Cardinalfish, Pterapogon kauderni, a mouthbrooding species that lacks a pelagic larval phase is focused on, and data show consistency between small and large-scale dispersal.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: September 11, 2019
2008 journal article
The effect of heterogeneous infectious period and contagiousness on the dynamics of Salmonella transmission in dairy cattle
Epidemiology and Infection, 136(11), 1496–1510.
Contributors: C. Lanzas* , S. Brien*, R. Ivanek *, Y. Lo *, P. Chapagain *, K. Ray*, P. Ayscue*, L. Warnick *, Y. Gröhn *
MeSH headings : Animals; Basic Reproduction Number; Cattle; Cattle Diseases / epidemiology; Cattle Diseases / microbiology; Cattle Diseases / transmission; Computer Simulation; Infection Control / methods; Models, Statistical; Prevalence; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / transmission; Time Factors
TL;DR:
The presence of super-shedders increases R0 and decreases the effectiveness of population-wise strategies to reduce infection, making necessary the application of strategies that target this specific group.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: September 9, 2019
2008 journal article
The risk and control of Salmonella outbreaks in calf-raising operations: A mathematical modeling approach
Veterinary Research, 39(6).
Contributors: C. Lanzas* , L. Warnick *, R. Ivanek *, P. Ayscue*, D. Nydam * & Y. Gröhn *
MeSH headings : Animal Husbandry; Animals; Cattle; Disease Outbreaks / veterinary; Models, Biological; Prevalence; Risk Factors; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / prevention & control
TL;DR:
The most effective strategies to control ongoing outbreaks were to completely close the rearing operation to incoming calves, to increase the proportion of admitted calves that were immunized (>75%), and to assign personnel and equipment to groups of calves.
(via Semantic Scholar)
Source: ORCID
Added: September 9, 2019
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