Recent Works

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Sorted by most recent date added to the index first, which may not be the same as publication date order.

2025 article

Response to reader comment on: Modeling the developing nervous system: a neuroscience perspective on the use of new approach methodologies in developmental neurotoxicity testing

Newell, A. J., & Patisaul, H. B. (2025, July 23). TOXICOLOGICAL SCIENCES, Vol. 7.

By: A. Newell n & H. Patisaul n

topics (OpenAlex): Anesthesia and Neurotoxicity Research
Sources: Web Of Science, NC State University Libraries
Added: August 4, 2025

2025 article

Genomic Evaluation of Canine Prostatic Carcinomas as a Model for the Human Disease

Thomas, R., Luff, J. A., Dickey, A. N., Dillon, M. N., Livingston, I. G., Schrag, C. A., … Breen, M. (2025, July 23). VETERINARY AND COMPARATIVE ONCOLOGY, Vol. 7.

By: R. Thomas n, J. Luff n, A. Dickey n, M. Dillon n, I. Livingston n, C. Schrag n, S. Suter n, M. Breen n

author keywords: adenocarcinoma; DNA copy number variations; dogs; mutation; prostatic neoplasms; urologic neoplasms
topics (OpenAlex): Veterinary Oncology Research; Veterinary Medicine and Surgery; Human-Animal Interaction Studies
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 28, 2025

2025 journal article

Two-stage estimators for spatial confounding with point-referenced data

BIOMETRICS, 81(3).

By: N. Wiecha, J. Hoppin & B. Reich

author keywords: bias reduction; double machine learning; Gaussian process; semiparametric regression
MeSH headings : Computer Simulation; Humans; Models, Statistical; Spatial Regression; Confounding Factors, Epidemiologic; Bias; Machine Learning; Biometry / methods; Data Interpretation, Statistical; Normal Distribution
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 24, 2025

2025 journal article

Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits

GENOME RESEARCH, 35(7), 1485–1502.

MeSH headings : Humans; Quantitative Trait Loci; Liver / metabolism; Chromatin / genetics; Chromatin / metabolism; Genome-Wide Association Study; Gene Expression Regulation; Transcription Factors / metabolism; Binding Sites; Polymorphism, Single Nucleotide
topics (OpenAlex): Epigenetics and DNA Methylation; Genomics and Chromatin Dynamics; Genetics and Neurodevelopmental Disorders
Source: Web Of Science
Added: July 21, 2025

2025 journal article

Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice☆

TOXICOLOGY AND APPLIED PHARMACOLOGY, 502.

co-author countries: Canada 🇨🇦
author keywords: Mice; MASH; Liver Pathology; Transcriptomics; Machine Leaning Pathologist Assistance
MeSH headings : Animals; Male; Female; Mice; Disease Models, Animal; Diet, High-Fat / adverse effects; Liver / pathology; Liver / metabolism; Transcriptome; Gene Expression Profiling / methods; Collaborative Cross Mice; Fatty Liver / genetics; Fatty Liver / pathology; Fatty Liver / metabolism; Non-alcoholic Fatty Liver Disease / genetics; Non-alcoholic Fatty Liver Disease / pathology
topics (OpenAlex): Liver Disease Diagnosis and Treatment; Endoplasmic Reticulum Stress and Disease; Hepatocellular Carcinoma Treatment and Prognosis
Source: Web Of Science
Added: July 21, 2025

2025 journal article

Variability of Mercury Concentrations Across Species, Brand, and Tissue Type in Processed Commercial Seafood Products

TOXICS, 13(6).

By: K. Rock n, S. Bhoothapuri n, E. Lassiter n, L. Segedie & S. Belcher n

author keywords: mercury; seafood; canned food; fish; tuna
topics (OpenAlex): Mercury impact and mitigation studies; Meat and Animal Product Quality; Toxic Organic Pollutants Impact
Sources: Web Of Science, NC State University Libraries
Added: June 30, 2025

2025 journal article

Conditional knockout of C/EBPβ in epidermis results in dysregulated lipid biosynthesis and a defect in skin barrier function

PLOS ONE, 20(6).

Ed(s): S. Raza

MeSH headings : Animals; Epidermis / metabolism; Mice; Mice, Knockout; Lipid Metabolism / genetics; Lipids / biosynthesis; CCAAT-Enhancer-Binding Proteins / genetics; CCAAT-Enhancer-Binding Proteins / metabolism; Keratinocytes / metabolism; Lipogenesis / genetics; Lipidomics
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 25, 2025

2025 journal article

Repetitive ozone exposure worsens features of muco-inflammatory disease in developed <i>Scnn1b</i>-Tg+ mice lungs

FRONTIERS IN TOXICOLOGY, 7.

By: T. Vo n, S. Patial* & Y. Saini n

author keywords: ozone; mice; <italic>Scnn1b</italic>-Tg+; lung; inflammation
topics (OpenAlex): Air Quality and Health Impacts; Medical and Biological Ozone Research; Climate Change and Health Impacts
Sources: Web Of Science, NC State University Libraries
Added: June 23, 2025

2025 journal article

TAK1 inhibition activates pore-forming proteins to block intracellular bacterial growth through modulating mitochondria

CELL DEATH & DISEASE, 16(1).

By: W. Lopez-Perez, R. Gonzalez-Calderon, K. Sai, P. Rai, J. Macstudy, Y. Sakamachi, C. Parsons, S. Kathariou, M. Fessler, J. Ninomiya-Tsuji

topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 18, 2025

2025 article

Dietary Iron Supplementation Protects Against Growth Restriction and Metabolic Dysfunction-Associated Steatotic Liver Disease in Perinatal Cadmium-Exposed Mice

Lichtler, R., Klossner, H., Smith, N., Hoyo, C., & Cowley, M. (2025, June 17). FASEB BIOADVANCES, Vol. 6.

author keywords: anemia; cadmium; dietary supplements; iron deficiency; liver diseases; maternal exposure; pregnancy
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 17, 2025

2025 journal article

Short-chain per- and polyfluoroalkyl substances associate with elevated alanine aminotransferase: Cross-sectional analysis results from the STRIVE cohort

ENVIRONMENTAL RESEARCH, 283.

By: B. Seo, H. Wang, R. Maguire, Y. Liu, B. Smith, K. Haller, M. Riggan, D. V. Conti ...

author keywords: [MeSH]; Fluorocarbons; Liver cirrhosis; Liver diseases; Alanine transaminase
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 17, 2025

2025 journal article

Differential methylation patterns in cord blood associated with prenatal exposure to neighborhood crime: an epigenome-wide association study and regional analysis

EPIGENETICS, 20(1).

By: C. Martin, J. Chen, . Alena S. D'Alessio, C. Ward-Caviness, A. Ye, E. Lodge, L. Ghastine, R. Dhingra ...

author keywords: EWAS; regional analysis; DNA methylation; cord blood; neighborhood crime; social epigenomics
MeSH headings : Humans; Female; DNA Methylation; Pregnancy; Fetal Blood / metabolism; Crime; Prenatal Exposure Delayed Effects / genetics; Adult; Male; Genome-Wide Association Study; Epigenesis, Genetic; Quantitative Trait Loci; Epigenome; Infant, Newborn; Neighborhood Characteristics
topics (OpenAlex):
Sources: Web Of Science, NC State University Libraries
Added: June 16, 2025

2025 journal article

Evaluating non-destructive sampling methods of parchment for genomic sequencing

NPJ HERITAGE SCIENCE, 13(1).

By: L. Diaz, M. Scheible*, T. Stinson*, I. Livingston*, M. Breen* & K. Meiklejohn*

topics (OpenAlex): Molecular Biology Techniques and Applications; Identification and Quantification in Food; Forensic and Genetic Research
Sources: Web Of Science, NC State University Libraries
Added: June 16, 2025

2025 review

The effects of developmental cadmium exposure on health and disease

[Review of ]. DISEASE MODELS & MECHANISMS, 18(6).

By: K. Hudson, L. Dameris, R. Lichtler & M. Cowley

author keywords: Cadmium; Developmental exposure; Exposure models; Fetal growth restriction; Disease programming; Organ systems
MeSH headings : Cadmium / toxicity; Humans; Animals; Pregnancy; Female; Environmental Exposure / adverse effects; Placenta / drug effects; Disease; Health; Prenatal Exposure Delayed Effects
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 9, 2025

2025 journal article

Airway epithelial cell-specific deletion of EGFR modulates mucoinflammatory features of cystic fibrosis-like lung disease in mice

FRONTIERS IN IMMUNOLOGY, 16.

author keywords: EGFR; cystic fibrosis; <italic>Scnn1b</italic>-Tg+; airway epithelium; mucus obstruction
MeSH headings : Animals; ErbB Receptors / genetics; ErbB Receptors / metabolism; ErbB Receptors / deficiency; Cystic Fibrosis / immunology; Cystic Fibrosis / pathology; Cystic Fibrosis / metabolism; Cystic Fibrosis / genetics; Mice; Mice, Transgenic; Disease Models, Animal; Epithelial Cells / metabolism; Epithelial Cells / immunology; Respiratory Mucosa / pathology; Respiratory Mucosa / metabolism; Respiratory Mucosa / immunology; Inflammation; Lung / pathology; Lung / immunology; Lung / metabolism; Mice, Knockout; Bronchoalveolar Lavage Fluid / immunology; Mucus / metabolism
topics (OpenAlex): Neonatal Respiratory Health Research; Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis; Inhalation and Respiratory Drug Delivery
Sources: Web Of Science, NC State University Libraries
Added: May 27, 2025

2025 journal article

Asian diversity in human immune cells

CELL, 188(8).

By: K. Kock*, L. Tan*, K. Han*, Y. Ando*, D. Jevapatarakul*, A. Chatterjee, Q. Lin*, E. Buyamin* ...

co-author countries: India 🇮🇳 Italy 🇮🇹 Japan 🇯🇵 Korea (Republic of) 🇰🇷 Singapore 🇸🇬 Thailand 🇹🇭
MeSH headings : Humans; Asian People / genetics; Single-Cell Analysis; Female; Male; Genetic Variation; Asia; Adult; Middle Aged
topics (OpenAlex): Immune Cell Function and Interaction; Immune responses and vaccinations; T-cell and B-cell Immunology
Source: Web Of Science
Added: May 27, 2025

2025 journal article

Toltrazuril sulfone (Ponazuril) residue depletion in pig tissues and estimated withdrawal intervals

REGULATORY TOXICOLOGY AND PHARMACOLOGY, 162.

author keywords: Ponazuril; Toltrazuril sulfone; Tissue residue; Withdrawal interval; Pig
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: May 27, 2025

2025 journal article

Polypoid Cystitis: A Retrospective Case-Series of 112 Dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, 39(3).

By: M. Price, R. Thomas, M. Breen, A. Kendall & S. Vaden

author keywords: bladder; BRAF V595E mutation; inflammatory; polyp; urinary tract
MeSH headings : Animals; Dogs; Cystitis / veterinary; Cystitis / pathology; Cystitis / diagnosis; Dog Diseases / pathology; Dog Diseases / diagnosis; Dog Diseases / diagnostic imaging; Retrospective Studies; Female; Male; Urinary Tract Infections / veterinary; Polyps / veterinary; Polyps / pathology
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: May 16, 2025

2025 article

Investigating the Pharmacokinetics and Efficacy of Intramammary Ceftiofur Hydrochloride in Prevention of Udder Inflammation in Non-Lactating Dairy Heifers

Miller, R. A., Smith, G. W., Halleran, J. L., Foster, D. M., & Baynes, R. E. (2025, April 21). JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, Vol. 4.

By: R. Miller n, G. Smith n, J. Halleran n, D. Foster n & R. Baynes n

author keywords: dairy heifers; intramammary ceftiofur; mastitis; milk residues; pharmacokinetics
topics (OpenAlex): Milk Quality and Mastitis in Dairy Cows; Probiotics and Fermented Foods; Animal Genetics and Reproduction
Sources: Web Of Science, NC State University Libraries
Added: May 6, 2025

2025 journal article

Exposure to phthalates and replacements during pregnancy in association with gestational blood pressure and hypertensive disorders of pregnancy

ENVIRONMENTAL RESEARCH, 279.

By: E. McNell, D. Stevens, B. Welch, E. Rosen, S. Fenton, A. Calafat, J. Botelho, E. Sinkovskaya ...

author keywords: Phthalates; Endocrine disruptors; Blood pressure; Preeclampsia; Hypertensive disorders of pregnancy
MeSH headings : Humans; Female; Pregnancy; Phthalic Acids / toxicity; Phthalic Acids / urine; Adult; Hypertension, Pregnancy-Induced / chemically induced; Hypertension, Pregnancy-Induced / epidemiology; Environmental Pollutants / toxicity; Environmental Pollutants / urine; Blood Pressure / drug effects; Prospective Studies; Biomarkers / urine; Maternal Exposure; Young Adult; Pre-Eclampsia / epidemiology; Pre-Eclampsia / chemically induced; Longitudinal Studies; Placenta
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: April 29, 2025

2025 journal article

Feasibility of IR-MALDESI Mass Spectrometry Imaging of PFAS

JOURNAL OF MASS SPECTROMETRY, 60(2).

author keywords: IR-MALDESI; LC-MS/MS; mass spectrometry imaging; PFAS; zebrafish
MeSH headings : Fluorocarbons / analysis; Animals; Mice; Limit of Detection; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Liver / chemistry; Liver / metabolism; Alkanesulfonic Acids / analysis; Caprylates / analysis; Feasibility Studies; Environmental Pollutants / analysis; Tandem Mass Spectrometry / methods; Zebrafish / metabolism
topics (OpenAlex): Per- and polyfluoroalkyl substances research; Lanthanide and Transition Metal Complexes; Mass Spectrometry Techniques and Applications
Sources: Web Of Science, NC State University Libraries
Added: April 28, 2025

2025 article

Modeling the developing nervous system: a neuroscience perspective on the use of new approach methodologies in developmental neurotoxicity testing

Newell, A. J., & Patisaul, H. B. (2025, April 15). TOXICOLOGICAL SCIENCES, Vol. 4.

By: A. Newell n & H. Patisaul n

author keywords: neurodevelopment; new approach methodologies; NAMs; models; developmental neurotoxicity testing; DNT
topics (OpenAlex): Neonatal and fetal brain pathology
Sources: Web Of Science, NC State University Libraries
Added: April 28, 2025

2025 journal article

Canonical Wnt pathway modulation is required to correctly execute multiple independent cellular dynamic programs during cranial neural tube closure

DEVELOPMENTAL BIOLOGY, 523, 115–131.

By: A. Bogart & E. Brooks

author keywords: Wnt; Lrp6; Apc; Neural tube closure; Apical constriction; Proliferation
MeSH headings : Animals; Wnt Signaling Pathway / physiology; Neural Tube / embryology; Neural Tube / metabolism; Neural Tube / cytology; Mice; Low Density Lipoprotein Receptor-Related Protein-6 / genetics; Low Density Lipoprotein Receptor-Related Protein-6 / metabolism; Cell Proliferation; Skull / embryology; Neural Tube Defects; Neural Crest / embryology; Wnt Proteins / metabolism; Neurulation
topics (OpenAlex):
Sources: ORCID, Web Of Science, NC State University Libraries
Added: April 23, 2025

2025 article

Trophic Transfer of Perfluoroalkyl Acids in a Periphyton-Mayfly-Zebrafish Food Chain

Farrell, M. R., Buchwalter, D. B., Weed, R. A., Enders, J. R., & Planchart, A. J. (2025, April 15).

By: M. Farrell, D. Buchwalter*, R. Weed, J. Enders* & A. Planchart

topics (OpenAlex): Per- and polyfluoroalkyl substances research
Source: ORCID
Added: April 15, 2025

2025 article

A workflow for human health hazard evaluation using transcriptomic data and Key Characteristics-based gene sets

Tsai, H.-H. D., Oware, K. D., Wright, F. A., Chiu, W. A., & Rusyn, I. (2025, April 3). TOXICOLOGICAL SCIENCES.

author keywords: transcriptomics; key characteristics; gene set enrichment; gene expression
topics (OpenAlex): Computational Drug Discovery Methods; Carcinogens and Genotoxicity Assessment; Gene expression and cancer classification
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 14, 2025

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