Toxicology Programs

When are novel methods for analyzing complex chemical mixtures in epidemiology beneficial?

Environmental Epidemiology.

Myeloid cell-specific HMGB1 deficiency exaggerates mucoinflammatory responses but promotes bacterial clearance in mucoinflammatory lung disease

Mao, Y., Patial, S., & Saini, Y. (2026, January 12). Scientific Reports.

Inferring toxicant susceptibility in global populations from gene-environment interactions involving the Aryl Hydrocarbon Receptor

Chimeh, U. S., Rogers, M. C., & Aylor, D. L. (2026, January 10).

Single-cell transcriptomics reveal alveolar macrophages-specific responses in single-hit ozone exposure model in mice

Vo, T., Choudhary, I., Patial, S., & Saini, Y. (2026, January 2). American Journal of Physiology-Lung Cellular and Molecular Physiology.

Site-Specific and Economic Optimization of Populus Plantations for Veneer Production in Appalachian Landscapes

Beyene, S., Blumenfeld, S., & Nichols, E. G. (2026, January 1). Geographies.

Comprehensive Transcriptomic and Epigenomic Insights into Environmental Toxicant Exposures: The TaRGET II Resource

Zhang, B. A., Miao, B., Fu, S., Coarfa, C., Kumar, R., Kuntala, P. K., … Walker, C. (2025, August 2). BioRxiv (Cold Spring Harbor Laboratory).

Early-Life Environmental Exposures Reprogram Epigenomic Aging to Alter Gene Expression Trajectories

Grimm, S. L., Jangid, R., Bartolomei, M. S., Dolinoy, D. C., Aylor, D. L., Mutlu, G. M., … Walker, C. L. (2025, April 22). BioRxiv (Cold Spring Harbor Laboratory).

Effects of Ambient Temperature During Pregnancy on Newborn Birthweight

Nargund, R., Marchesoni, J., Bareja, A., Sosnowski, D. W., Peng, G., Hoyo, C., … Murphy, S. K. (2025, June 15). BioRxiv (Cold Spring Harbor Laboratory).

Age-specific DNA methylation alterations in sperm at imprint control regions may contribute to the risk of autism spectrum disorder in offspring

Casella, E., Depovere, J., Delger, C., Butynets, M., Antczak, P., Price, T., … Soubry, A. (2025, December 29). Aging.

β-Lactoglobulin – PFAS Binding Interactions Identifies the Calyx Domain as a Determinant of Contaminated Milk Exposure and the Calycin Protein Family as Potential Mediators of PFAS Toxicity

Toxicological Sciences.

Cyfip2 mediates sensorimotor integration of visual input through Rac1-dependent actin remodeling

Charron, K. M., Cole, D. C., Hancock, M. B., Sumathipala, S. H., Johnson, A. L. B., Frazier, K. J., & Marsden, K. C. (2025, December 23). (Vol. 12). Vol. 12.

Genetically engineered ESC-derived embryos reveal Vinculin-dependent force responses required for mammalian neural tube closure

Prudhomme, I. S., Brooks, E. R., Taneja, N., Bhattacharya, B., LaFleche, B. J., Furuta, Y., & Zallen, J. A. (2025, December 25).

GPR161–GLI3 repressor signaling at cilia directs apical constriction and cell fate during cranial neural tube closure

Development.

GLCave-WHO Cone test mortality data of three filth fly species when exposed to diatomaceous earth

Cave, G., Chen, K., Denning, S. S., Watson, D. W., & Roe, R. M. (2025, December 2). DRYAD.

Contaminant Accumulation by Unionid Mussels: An Assemblage Level Assessment of Sequestration Functions Across Watersheds and Spatial Scales

Archambault, J. M., Cope, W. G., Newton, T. J., Dunn, H. L., Eads, C. B., Jones, J. W., & Cope, W. R. (2025, December 12). Diversity, Vol. 12.

Tristetraprolin protects against ozone-induced acute lung injury and inflammation in mice

Lamichhane, R., Choudhary, I., Singamsetty, D., Patial, S., & Saini, Y. (2025, December 11). The Journal of Immunology.

Protecting the environment pays off for the USA economy and public health

Hannan, M., Hatinoglu, D., Blaney, L., Vikesland, P., Knappe, D., Miller, R., & Apul, O. (2025, December 11). Nature Water.

Prior acute ozone injury dampens Th2 responses to subsequent repetitive ozone exposures in mice

Paudel, K., Patial, S., & Saini, Y. (2025, December 9).

Data from Extended Human Papillomavirus Genotyping to Predict Progression to High-Grade Cervical Precancer: A Prospective Cohort Study in the Southeastern United States

Bukowski, A., Hoyo, C., Hudgens, M. G., Brewster, W. R., Valea, F., Bentley, R. C., … Smith, J. S. (2025, November 26).

Supplementary Figure from Extended Human Papillomavirus Genotyping to Predict Progression to High-Grade Cervical Precancer: A Prospective Cohort Study in the Southeastern United States

Bukowski, A., Hoyo, C., Hudgens, M. G., Brewster, W. R., Valea, F., Bentley, R. C., … Smith, J. S. (2025, November 26).

Supplementary Figure from Extended Human Papillomavirus Genotyping to Predict Progression to High-Grade Cervical Precancer: A Prospective Cohort Study in the Southeastern United States

Bukowski, A., Hoyo, C., Hudgens, M. G., Brewster, W. R., Valea, F., Bentley, R. C., … Smith, J. S. (2025, November 26).

Supplementary Table from Extended Human Papillomavirus Genotyping to Predict Progression to High-Grade Cervical Precancer: A Prospective Cohort Study in the Southeastern United States

Bukowski, A., Hoyo, C., Hudgens, M. G., Brewster, W. R., Valea, F., Bentley, R. C., … Smith, J. S. (2025, November 26).

Supplementary Table from Extended Human Papillomavirus Genotyping to Predict Progression to High-Grade Cervical Precancer: A Prospective Cohort Study in the Southeastern United States

Bukowski, A., Hoyo, C., Hudgens, M. G., Brewster, W. R., Valea, F., Bentley, R. C., … Smith, J. S. (2025, November 26).

Supplementary Table from Extended Human Papillomavirus Genotyping to Predict Progression to High-Grade Cervical Precancer: A Prospective Cohort Study in the Southeastern United States

Bukowski, A., Hoyo, C., Hudgens, M. G., Brewster, W. R., Valea, F., Bentley, R. C., … Smith, J. S. (2025, November 26).

Supplementary Table from Extended Human Papillomavirus Genotyping to Predict Progression to High-Grade Cervical Precancer: A Prospective Cohort Study in the Southeastern United States

Bukowski, A., Hoyo, C., Hudgens, M. G., Brewster, W. R., Valea, F., Bentley, R. C., … Smith, J. S. (2025, November 26).