Works Published in 2002

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Displaying works 1 - 20 of 47 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2002 report

A workbook and key to the freshwater bivalves of North Carolina

Raleigh, NC: North Carolina Museum of Natural Sciences and North Carolina State University.

By: A. Bogan, W. Cope, J. Alderman & T. Savidge

Source: NC State University Libraries
Added: September 23, 2022

2002 journal article

Toxicant induced differential gene expression and production of an aquatic gene array

The MDIBL Bulletin, 41, 58–61.

By: S. Kullman & D. Hinton

Source: NC State University Libraries
Added: September 16, 2022

2002 journal article

Molecular cloning of rainbow trout (Oncorhynchus mykiss) eggshell zona radiata protein complementary DNA: mRNA expression in 17β-estradiol- and nonylphenol-treated fish

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 132(2), 315–326.

By: A. Arukwe, S. Kullman*, K. Berg*, A. Goksøyr* & D. Hinton*

author keywords: eggshell protein; cDNA cloning; liver; gene expression; xenoestrogen; biomarkers; environmental monitoring
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA Primers / genetics; DNA, Complementary / genetics; Egg Proteins / genetics; Egg Shell / chemistry; Estradiol / pharmacology; Gene Expression Profiling; Gene Expression Regulation / drug effects; Molecular Sequence Data; Oncorhynchus mykiss / genetics; Phenols / pharmacology; Phylogeny; Polymerase Chain Reaction; RNA, Messenger / genetics; RNA, Messenger / metabolism; Receptors, Estrogen / genetics; Vitellogenins / genetics
TL;DR: The differential time-dependent transcriptional and translational expression and use of Zrp, ER and Vtg as sensitive biomarkers in environmental monitoring of endocrine disrupters in fish is discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 15, 2022

2002 journal article

DNA binding properties of the yeast Msh2-Msh6 and Mlh1-Pms1 heterodimers

Biological Chemistry, 383(6), 969–975.

By: K. Drotschmann, M. Hall, P. Shcherbakova, H. Wang, D. Erie, F. Brownewell, E. Kool, T. Kunkel

Source: ORCID
Added: September 23, 2021

2002 journal article

A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3'-5'exonuclease and 5'-protruding strand endonuclease activities

Biochemistry, 41(9), 2901–2912.

By: Y. Xue, G. Ratcliff, H. Wang, P. Davis-Searles, M. Gray, D. Erie, M. Redinbo

Source: ORCID
Added: September 23, 2021

2002 chapter

Biological Processes

In A. W. Andren & T. W. Bober (Eds.), Silver in the Environment: Transport, Fate and Effects (pp. 65–96). Pensacola, FL: SETAC Press.

By: S. Luoma, C. Hogstrand, R. Bell, G. Bielmyer, F. Galvez, G. LeBlanc, B. Lee, T. Purcell ...

Ed(s): A. Andren & T. Bober

Source: NC State University Libraries
Added: March 26, 2021

2002 journal article

The Mouse Genome Database (MGD): the model organism database for the laboratory mouse

Nucleic Acids Research, 30(1), 113–115.

By: J. Blake*, J. Richardson*, C. Bult*, J. Kadin*, J. Eppig*, R. Baldarelli, M. Baya, J. Beal ...

Contributors: J. Blake*, J. Richardson*, C. Bult*, J. Kadin*, J. Eppig*, R. Baldarelli, M. Baya, J. Beal ...

MeSH headings : Alleles; Animals; Chromosome Mapping; Data Collection; Database Management Systems; Databases, Genetic; Genome; Genotype; Humans; Information Storage and Retrieval; Internet; Mice / genetics; Mutation; Phenotype; Radiation Hybrid Mapping; Rats; Sequence Homology; User-Computer Interface; Vocabulary, Controlled
TL;DR: Recent integration of large datasets of mouse full-length cDNAs and radiation-hybrid mapped ESTs, the continued development and use of extensive structured vocabularies and the expansion of the representation of phenotypes highlight this year's developments. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: March 16, 2021

2002 journal article

Time course and manner of Purkinje neuron death following a single ethanol exposure on postnatal day 4 in the developing rat

Neuroscience, 114(2), 327–337.

By: K. Light*, S. Belcher* & D. Pierce*

Contributors: K. Light*, S. Belcher* & D. Pierce*

author keywords: cerebellum; neuronal development; apoptosis; caspase-3; cytochrome c
MeSH headings : Alcohol-Induced Disorders, Nervous System / metabolism; Alcohol-Induced Disorders, Nervous System / pathology; Alcohol-Induced Disorders, Nervous System / physiopathology; Animals; Animals, Newborn; Apoptosis / drug effects; Apoptosis / physiology; Calbindin 1; Calbindins; Caspase 3; Caspases / drug effects; Caspases / metabolism; Cerebellar Cortex / drug effects; Cerebellar Cortex / growth & development; Cerebellar Cortex / pathology; Cytochrome c Group / drug effects; Cytochrome c Group / metabolism; Drug Administration Schedule; Ethanol / toxicity; Female; Fetal Alcohol Spectrum Disorders / metabolism; Fetal Alcohol Spectrum Disorders / pathology; Fetal Alcohol Spectrum Disorders / physiopathology; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mitochondria / drug effects; Mitochondria / metabolism; Mitochondria / pathology; Nerve Degeneration / chemically induced; Nerve Degeneration / metabolism; Nerve Degeneration / physiopathology; Pregnancy; Prenatal Exposure Delayed Effects; Purkinje Cells / drug effects; Purkinje Cells / metabolism; Purkinje Cells / pathology; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G / metabolism; Time Factors
TL;DR: The data demonstrate that a single dose of ethanol results in a significant and extensive, lobular dependent loss of Purkinje cells within 24 h after administration, and support the hypothesis that ethanol-induced loss ofPurkinje Cells involves apoptotic mechanisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: March 5, 2021

2002 journal article

Ethanol-induced alterations of neurotrophin receptor expression on Purkinje cells in the neonatal rat cerebellum

Brain Research, 924(1), 71–81.

By: K. Light*, D. Brown*, B. Newton*, S. Belcher* & C. Kane*

Contributors: K. Light*, D. Brown*, B. Newton*, S. Belcher* & C. Kane*

author keywords: cerebellum; truncated TrkB; TrkC; ethanol exposure; immunohistochemical
MeSH headings : Alcohol-Induced Disorders, Nervous System / metabolism; Alcohol-Induced Disorders, Nervous System / physiopathology; Animals; Brain-Derived Neurotrophic Factor / metabolism; Cell Differentiation / drug effects; Cell Differentiation / physiology; Cerebellar Cortex / drug effects; Cerebellar Cortex / growth & development; Cerebellar Cortex / pathology; Ethanol / pharmacology; Female; Fetal Alcohol Spectrum Disorders / metabolism; Fetal Alcohol Spectrum Disorders / physiopathology; Immunohistochemistry; Male; Nerve Degeneration / chemically induced; Nerve Degeneration / metabolism; Nerve Degeneration / physiopathology; Nerve Growth Factors / metabolism; Neurotrophin 3 / metabolism; Pregnancy; Purkinje Cells / drug effects; Purkinje Cells / metabolism; Purkinje Cells / pathology; Rats; Rats, Sprague-Dawley; Receptor, trkB / metabolism; Receptor, trkC / metabolism; Receptors, Nerve Growth Factor / drug effects; Receptors, Nerve Growth Factor / metabolism
TL;DR: Ethanol selectively decreased Purkinje cell expression of TrkB and TrkC receptors following exposures within the vulnerable period (PN4-6), suggesting that ethanol may induce loss ofPurkinje cells by alteration of neurotrophic regulation at this critical stage. (via Semantic Scholar)
Source: ORCID
Added: March 5, 2021

2002 journal article

Estrogen regulates GFAP-expression in specific subnuclei of the female rat interpeduncular nucleus: A potential role for estrogen receptor β

Brain Research, 958(2), 488–496.

By: A. Zsarnovszky*, T. Smith*, F. Hajos* & S. Belcher*

Contributors: A. Zsarnovszky*, T. Smith*, F. Hajos* & S. Belcher*

author keywords: astrocyte; estrogen; estrogen receptor betas; glia, glial fibrillary acidic protein immunohistochemistry; interpeduncular nucleus
MeSH headings : Animals; Estradiol / pharmacology; Estrogen Receptor beta; Estrogens / pharmacology; Female; Glial Fibrillary Acidic Protein / analysis; Glial Fibrillary Acidic Protein / biosynthesis; Mesencephalon / chemistry; Mesencephalon / drug effects; Mesencephalon / metabolism; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Estrogen / analysis; Receptors, Estrogen / physiology
TL;DR: Results indicate that E(2), in the absence of other ovarian hormones, modulates GFAP-expression within select IPN subnuclei and that these affects are dependent on position along the AP axis and suggest that in the IPN, E( 2) may directly modulateGFAP- expression through ERbeta-mediated mechanisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: March 5, 2021

2002 journal article

In the (adsorption) competition between NOM and MIB, who is the winner, and why?

Water Science and Technology: Water Supply, 2(2), 59–67.

By: G. Newcombe*, J. Morrison, C. Hepplewhite & D. Knappe n

Contributors: G. Newcombe*, J. Morrison, C. Hepplewhite & D. Knappe n

author keywords: activated carbon; adsorption; MIB; tastes and odours
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Crossref, ORCID
Added: August 28, 2020

2002 journal article

Laser micropyrolysis GC–MS of lignin

Journal of Analytical and Applied Pyrolysis, 62(2), 365–373.

By: P. Greenwood*, J. van Heemst*, E. Guthrie* & P. Hatcher*

author keywords: micropyrolysis; laser pyrolysis; GC-MS; lignin; guaiacyl; syringyl
TL;DR: The potential for using lasers as a highly directional thermal source in analytical pyrolysis studies is further investigated by the laser micropyrolyses GC–MS analysis of lignin moieties. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 14, 2020

2002 journal article

Reproducibility of urinary phthalate metabolites in first morning urine samples.

Environmental Health Perspectives, 110(5), 515–518.

By: J. Hoppin*, J. Brock*, B. Davis* & D. Baird*

Contributors: J. Hoppin*, J. Brock*, B. Davis* & D. Baird*

author keywords: biologic markers; environmental exposure; phthalates; reliability; urine; women's health
MeSH headings : Adult; Biomarkers / analysis; Chromatography, High Pressure Liquid; Environmental Exposure; Female; Half-Life; Humans; Middle Aged; Phthalic Acids / urine; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling; Urinalysis
TL;DR: The results suggest that even with the short half-lives of phthalates, women's patterns of exposure may be sufficiently stable to assign an exposure level based on a single first morning void urine measurement. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2019

2002 journal article

Prevalence of exposure to solvents, metals, grain dust, and other hazards among farmers in the Agricultural Health Study

Journal of Exposure Science & Environmental Epidemiology, 12(6), 418–426.

By: J. Coble*, J. Hoppin*, L. Engel*, O. Elci*, M. Dosemeci*, C. Lynch*, M. Alavanja*

Contributors: J. Coble*, J. Hoppin*, L. Engel*, O. Elci*, M. Dosemeci*, C. Lynch*, M. Alavanja*

author keywords: confounding; exposure; farmers; pesticides
MeSH headings : Agriculture; Confounding Factors, Epidemiologic; Dust; Epidemiologic Studies; Female; Humans; Iowa / epidemiology; Male; Metals, Heavy / adverse effects; Metals, Heavy / analysis; Middle Aged; North Carolina / epidemiology; Occupational Exposure; Occupational Health; Pesticides / adverse effects; Pesticides / analysis; Prevalence; Risk Assessment; Solvents / adverse effects; Solvents / analysis
TL;DR: The associations between the use of pesticides and the frequency with which the farmers in the AHS reported performing various types of specific farming activities were assessed to evaluate potential confounding, suggesting the magnitude of bias due to confounding is likely to be minimal. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2002 journal article

Potential for selection bias with tumor tissue retrieval in molecular epidemiology studies

Annals of Epidemiology, 12(1), 1–6.

By: J. Hoppin*, P. Tolbert, J. Taylor, J. Schroeder & E. Holly

Contributors: J. Hoppin*, P. Tolbert, J. Taylor, J. Schroeder & E. Holly

author keywords: molecular epidemiology; selection bias; tumor tissue
MeSH headings : Aged; California / epidemiology; Female; Humans; Male; Middle Aged; Molecular Epidemiology; Pancreatic Neoplasms / diagnosis; Pancreatic Neoplasms / epidemiology; Pancreatic Neoplasms / pathology; SEER Program; Selection Bias
TL;DR: The potential for bias associated with differential availability of tumor blocks is discussed including consideration of tumor, patient, and hospital characteristics and the determinants of selection are described in all studies using tumor tissue. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: September 13, 2019

2002 journal article

Chemical Predictors of Wheeze among Farmer Pesticide Applicators in the Agricultural Health Study

American Journal of Respiratory and Critical Care Medicine, 165(5), 683–689.

Contributors: J. Hoppin*, D. Umbach*, S. London*, M. Alavanja* & D. Sandler*

MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Asthma / chemically induced; Asthma / epidemiology; Causality; Cohort Studies; Female; Humans; Iowa; Male; Middle Aged; North Carolina; Pesticides / adverse effects; Respiratory Sounds / etiology; Risk Factors
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: September 13, 2019

2002 journal article

Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: A population-based, case-control study in the Southeastern United States

Arthritis & Rheumatism, 46(7), 1840–1850.

By: C. Parks, G. Cooper, L. Nylander-French, W. Sanderson, J. Dement, P. Cohen, M. Dooley, E. Treadwell ...

Contributors: C. Parks, G. Cooper, L. Nylander-French, W. Sanderson, J. Dement, P. Cohen, M. Dooley, E. Treadwell ...

MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Educational Status; Female; Humans; Logistic Models; Lupus Erythematosus, Systemic / chemically induced; Lupus Erythematosus, Systemic / epidemiology; Male; Middle Aged; Occupational Exposure; Prevalence; Racial Groups; Silicon Dioxide / adverse effects; Southeastern United States / epidemiology
TL;DR: It is suggested that crystalline silica exposure may promote the development of SLE in some individuals and additional research is recommended in other populations. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2002 journal article

Accuracy of self-reported pesticide use duration information from licensed pesticide applicators in the Agricultural Health Study

Journal of Exposure Science & Environmental Epidemiology, 12(5), 313–318.

By: J. Hoppin*, F. Yucel*, M. Dosemeci* & D. Sandler*

Contributors: J. Hoppin*, F. Yucel*, M. Dosemeci* & D. Sandler*

author keywords: accuracy; farmers; pesticides; pesticide registration; questionnaire
MeSH headings : Epidemiologic Studies; Humans; Mental Recall; Occupational Exposure; Pesticides / chemistry; Pesticides / classification; Quality Control; Reproducibility of Results; Retrospective Studies; Time Factors
TL;DR: The quality of the self-reported pesticide product use history of 57,311 licensed pesticide applicators in the Agricultural Health Study is compared to the year the pesticide active ingredient was first registered for use to suggest participants provide plausible information regarding their pesticide use. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2002 journal article

A Quantitative Approach for Estimating Exposure to Pesticides in the Agricultural Health Study

The Annals of Occupational Hygiene, 46(2), 245–260.

By: M. Dosemeci*, M. Alavanja, A. Rowland, D. Mage, S. Zahm, N. Rothman, J. Lubin, J. Hoppin*, D. Sandler, A. Blair

Contributors: M. Dosemeci*, M. Alavanja, A. Rowland, D. Mage, S. Hoar Zahm, N. Rothman, J. Lubin, J. Hoppin*, D. Sandler, A. Blair

author keywords: exposure assessment; pesticide exposure; agricultural exposures; farmers; pesticide applicators; occupational exposures
MeSH headings : Accidents, Occupational; Agriculture; Algorithms; Humans; Iowa; North Carolina; Occupational Exposure; Pesticides / poisoning; Prospective Studies; Protective Clothing; Risk Assessment / methods; Surveys and Questionnaires
TL;DR: A quantitative method to estimate long-term chemical-specific pesticide exposures in a large prospective cohort study of more than 58000 pesticide applicators in North Carolina and Iowa found that the take-home questionnaire sub-cohort of applicators is representative of the entire cohort in terms of exposure. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2002 journal article

Neurobehavioral actions of coumestrol and related isoflavonoids in rodents

Neurotoxicology and Teratology, 24(1), 47–54.

By: P. Whitten*, H. Patisaul* & L. Young*

author keywords: phytoestrogens; coumestrol; isoflavones; genistein; daidzein; endocrine disrupters; estrogen; sex behavior; ER alpha; ER beta
MeSH headings : Animals; Animals, Suckling; Coumestrol / pharmacology; Estrogens, Non-Steroidal / pharmacology; Female; Gene Expression / drug effects; Isoflavones / pharmacology; Male; Mice; Rats; Receptors, Estrogen / genetics; Sexual Behavior, Animal / drug effects
TL;DR: It is shown that even small, physiologically relevant exposure levels can alter estrogen-dependent gene expression in the brain and complex behavior, and that, in spite of their preferential affinity for ERbeta, isoflavonoids act through both ER(alpha) and ERbeta. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 18, 2019

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