Works Published in 2022
Displaying works 1 - 20 of 151 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2022 journal article
Comparing Rates of Change in SARS-CoV-2 Wastewater Load and Clinical Cases in 19 Sewersheds Across Four Major Metropolitan Areas in the United States
ACS ES&T Water.
TL;DR:
A wastewater sensitivity threshold is estimated-supporting the use of relative, rather than absolute, measures of SARS-CoV-2 wastewater data for more interoperable data sets.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: March 21, 2024
2022 journal article
Oxytocin release in stressful times
Psychoneuroendocrinology, 140, 105709.
manuscript.elsevier.com (publisher PDF)
Source: ORCID
Added: January 28, 2024
2022 journal article
Impaired KDM2B-mediated PRC1 recruitment to chromatin causes defective neural stem cell self-renewal and ASD/ID-like behaviors
IScience, 25(2), 103742.
TL;DR:
A critical role of KDM2B in normal brain development is revealed, a causality between the Kdm2b mutation and ASD/ID-like phenotypes in mice are revealed, and potential molecular mechanisms linking the function of K DM2B-PRC1 in transcriptional regulation to the 12q24.31 microdeletion-associated ASD/ ID are proposed.
(via Semantic Scholar)
Source: ORCID
Added: January 28, 2024
2022 journal article
Early life adversity drives sex-specific anhedonia and meningeal immune gene expression through mast cell activation
Brain, Behavior, and Immunity, 103, 73–84.
TL;DR:
The results indicate that ELA induces long-term meningeal immune gene changes and heightened sensitivity to adult stress-induced behavioral and meningealing immune responses and that these effects could mediated via mast cells.
(via Semantic Scholar)
Source: ORCID
Added: January 28, 2024
2022 journal article
Select Per- and Polyfluoroalkyl Substances (PFAS) Induce Resistance to Carboplatin in Ovarian Cancer Cell Lines
International Journal of Molecular Sciences, 23(9), 5176.
MeSH headings : Alkanesulfonic Acids / toxicity; Carboplatin / pharmacology; Carcinoma, Ovarian Epithelial; Cell Line; Environmental Pollutants / toxicity; Female; Fluorocarbons / toxicity; Humans; Ovarian Neoplasms / drug therapy
TL;DR:
This is the first study to demonstrate that, at sub-cytotoxic concentrations, select PFAS and PFAS mixtures increased survival fraction in ovarian cancer cells following carboplatin treatment, indicative of platinum resistance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
6. Clean Water and Sanitation
(Web of Science)
Source: ORCID
Added: October 28, 2023
2022 journal article
Per- and poly-fluoroalkyl substances (PFAS) and female reproductive outcomes: PFAS elimination, endocrine-mediated effects, and disease
Toxicology, 465, 153031.
MeSH headings : Endocrine Disruptors / adverse effects; Endocrine System Diseases / chemically induced; Endocrine System Diseases / metabolism; Endocrine System Diseases / physiopathology; Environmental Exposure / adverse effects; Environmental Pollutants / adverse effects; Female; Fertility / drug effects; Humans; Hydrocarbons, Fluorinated / adverse effects; Infertility, Female / chemically induced; Infertility, Female / metabolism; Infertility, Female / physiopathology; Menstrual Cycle / drug effects; Pregnancy; Pregnancy Complications / chemically induced; Pregnancy Complications / metabolism; Pregnancy Complications / physiopathology; Prognosis; Reproduction / drug effects; Risk Assessment; Risk Factors
TL;DR:
The role of a variety of PFAS and PFAS mixtures in female reproductive tract dysfunction and disease is summarized and the role ofPFAS in breast, thyroid, and hypothalamic-pituitary-gonadal axis function is discussed as the interplay between these tissues may be critical in understanding the long-term reproductive health effects of PFas in women.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: ORCID
Added: October 28, 2023
2022 journal article
Current Breast Milk PFAS Levels in the United States and Canada: After All This Time, Why Don’t We Know More?
Environmental Health Perspectives.
TL;DR:
Exceeding a children’s drinking water screening value does not indicate that adverse health effects will occur and should not be interpreted as a reason to not breastfeed; it indicates that the situation should be further evaluated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: October 28, 2023
2022 journal article
Chemical Effects on Breast Development, Function, and Cancer Risk: Existing Knowledge and New Opportunities
Current Environmental Health Reports.
TL;DR:
Increasing the rigor of MG assessment would improve the ability to identify chemicals of concern, regulate those chemicals based on their effects, and prevent exposures and associated adverse health effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: October 28, 2023
2022 journal article
PFAS are forever? The state of the science and research needs for analyzing and treating PFAS‐laden water
AWWA Water Science.
TL;DR:
This juxtaposition of factors combined with a lack of standardized analytical methods, health effects data, and treatment options for the vast majority of PFAS identified in the environment have created a complex regulatory and social dynamic.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: September 9, 2023
2022 journal article
Granular activated carbon adsorption of perfluoroalkyl acids from ground and surface water
AWWA Water Science.
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: September 9, 2023
2022 journal article
Correction to “Per- and Polyfluoroalkyl Substance (PFAS) Transport from Groundwater to Streams near a PFAS Manufacturing Facility in North Carolina, USA”
Correction to “Per- and Polyfluoroalkyl Substance (PFAS) Transport from Groundwater to Streams near a PFAS Manufacturing Facility in North Carolina, USA.” Environmental Science & Technology, 56(12), 9145–9145.
Source: ORCID
Added: September 9, 2023
2022 journal article
Silencing of RNA binding protein, ZFP36L1, promotes epithelial-mesenchymal transition in liver cancer cells by regulating transcription factor ZEB2.
Cellular Signalling, 9.
TL;DR:
The results demonstrate that ZFP36L1 suppresses EMT in hepatic cancer cells by down-regulating the expression of EMT-inducing transcription factor, ZEB2 and suggest an important role of ZFP 36L1 in the development, progression, and metastasis of hepatocellular cancer.
(via Semantic Scholar)
Source: ORCID
Added: August 2, 2023
2022 journal article
Ozone exposure upregulates the expression of host susceptibility protein TMPRSS2 to SARS-CoV-2.
Scientific Reports, 1.
MeSH headings : Animals; COVID-19 / chemically induced; COVID-19 / metabolism; Disease Susceptibility / chemically induced; Disease Susceptibility / metabolism; Macrophages, Alveolar / metabolism; Mice; Ozone / toxicity; SARS-CoV-2 / metabolism; Serine Endopeptidases / metabolism; Up-Regulation / drug effects
TL;DR:
The data indicate that the unhealthy levels of ozone in the environment may predispose individuals to severe SARS-CoV-2 infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2022 article
NLRP3 inflammasome is dispensable in methicillin resistant<i>Staphylococcus aureus</i>urinary tract infection
Paudel, S., Rogers, K. A., Kumar, R., Saini, Y., Patial, S., & Kulkarni, R. (2022, November).
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2022 journal article
Induction of whole-body gene deletion <i>via</i> R26-regulated tamoxifen-inducible Cre recombinase activity.
Frontiers in Pharmacology.
TL;DR:
It is demonstrated that a combination of TAM-diet with either TAM-injections or TAM-oral gavage can be employed for the efficient deletion of a gene in the whole body and no recombination was evident in any of the tissues examined from the control mice.
(via Semantic Scholar)
Source: ORCID
Added: August 2, 2023
2022 journal article
In Vitro Screening Method for Characterization of Macrophage Activation Responses.
Methods and Protocols, 8.
TL;DR:
A high-throughput and stringent assay to determine macrophage activation markers developed in this article can be adapted for biomarker determination in pathological conditions and toxicant/drug safety screening.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2022 journal article
Higher susceptibility of males to bleomycin-induced pulmonary inflammation is associated with sex-specific transcriptomic differences in myeloid cells.
Toxicology and Applied Pharmacology, 11.
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Bleomycin / toxicity; Chemokine CXCL10 / adverse effects; Cytokines; Female; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis / pathology; Inflammation / chemically induced; Inflammation / drug therapy; Inflammation / genetics; Interleukin-10; Interleukin-6; Interleukin-7; Lung; Lung Injury / pathology; Male; Mice; Mice, Inbred C57BL; Myeloid Cells; Pneumonia / chemically induced; RNA; Transcriptome
TL;DR:
There are inherent transcriptomic differences between the male and female lung myeloid cells and that the pro-inflammatory nature of male myeloids cells is sufficient to increase the susceptibility of female mice to BLM-induced inflammation.
(via Semantic Scholar)
Source: ORCID
Added: August 2, 2023
2022 journal article
Case report: <i>Mafb</i> promoter activity may define the alveolar macrophage dichotomy.
Frontiers in Immunology.
MeSH headings : Mice; Animals; Macrophages, Alveolar / metabolism; Macrophages / metabolism; Lung / metabolism; Promoter Regions, Genetic; Proteins / metabolism; MafB Transcription Factor / genetics; MafB Transcription Factor / metabolism
TL;DR:
A strain that expresses mTOM protein in all the cells of mouse body except for those that express Mafb-Cre-regulated mEGFP provides a unique tool to induce gene deletion in alveolar macrophages that encounter Th2 microenvironment in the lung airspaces.
(via Semantic Scholar)
Source: ORCID
Added: August 2, 2023
2022 journal article
Activating transcription factor 6 protects against endothelial barrier dysfunction.
Cellular Signalling, 11.
MeSH headings : Actin Depolymerizing Factors / metabolism; Activating Transcription Factor 6 / metabolism; Activating Transcription Factor 6 / pharmacology; Animals; Cattle; Cells, Cultured; Dextrans / metabolism; Dextrans / pharmacology; Endothelial Cells / metabolism; Fluorescein-5-isothiocyanate / analogs & derivatives; Fluorescein-5-isothiocyanate / metabolism; Fluorescein-5-isothiocyanate / pharmacology; Lipopolysaccharides / metabolism; Lipopolysaccharides / pharmacology; RNA, Small Interfering / metabolism; Respiratory Distress Syndrome; Sepsis
TL;DR:
ATF6 activation protects against endothelial barrier function, suggesting that this UPR sensor may serve as a therapeutic target for sepsis and ARDS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2022 article
Editorial: Women in developmental and reproductive toxicology: 2021
Adibi, J. J., Christiansen, S., Fenton, S. E., Holloway, A., & Patisaul, H. B. (2022, October 3). FRONTIERS IN TOXICOLOGY, Vol. 4.
author keywords: mentor; women's health; gender; fetal; mammary gland; placenta
UN Sustainable Development Goal Categories
5. Gender Equality
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 26, 2023
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