Works Published in 2014
Displaying works 101 - 120 of 218 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 journal article
GENE-LEVEL PHARMACOGENETIC ANALYSIS ON SURVIVAL OUTCOMES USING GENE-TRAIT SIMILARITY REGRESSION
ANNALS OF APPLIED STATISTICS, 8(2), 1232–1255.
author keywords: Association study; gene/pathway; pharmacogenetics; similarity regression; survival data; proportional odds model; proportional hazards model
TL;DR:
A gene-trait similarity regression for survival analysis to assess the effect of a gene or pathway on time-to-event outcomes and derives the equivalence between the similarity survival regression and a random effects model, which further unifies the current variance-component based methods.
(via Semantic Scholar)
doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 article
Estimation of optimal dynamic treatment regimes
Zhao, Y.-Q., & Laber, E. B. (2014, August). CLINICAL TRIALS, Vol. 11, pp. 400–407.
TL;DR:
The purpose of this article is to review recent methodological progress and applied issues associated with estimating optimal dynamic treatment regimes using sequential multiple assignment randomized trials data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Distance majorization and its applications
MATHEMATICAL PROGRAMMING, 146(1-2), 409–436.
author keywords: Constrained optimization; Majorization-minimization (MM); Sequential unconstrained minimization; Projection
TL;DR:
This proposal is an instance of a sequential unconstrained minimization technique and revolves around three ideas: the majorization-minimization principle, the classical penalty method for constrained optimization, and quasi-Newton acceleration of fixed-point algorithms.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
DYNAMIC MODELING OF BEHAVIOR CHANGE
QUARTERLY OF APPLIED MATHEMATICS, 72(2), 209–251.
author keywords: Mathematical psychology; inverse problems; delay differential equations; behavior change; model comparison
TL;DR:
This work presents a novel dynamical systems modeling approach to understand the processes governing an individual’s behavior in the context of problem drinking, and discusses the construction of an initial mathematical model for two starkly distinct individuals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Bifurcation analysis of a menstrual cycle model reveals multiple mechanisms linking testosterone and classical PCOS
JOURNAL OF THEORETICAL BIOLOGY, 361, 31–40.
author keywords: Hysteresis; Parameters; Estradiol; Follicle; Pituitary
MeSH headings : Female; Humans; Luteinizing Hormone / metabolism; Menstrual Cycle; Models, Biological; Pituitary Gland / metabolism; Pituitary Gland / physiopathology; Polycystic Ovary Syndrome / metabolism; Polycystic Ovary Syndrome / physiopathology
TL;DR:
The model suggests that for some women androgenic activity at the levels of both the pituitary and the ovaries may contribute to the etiology of PCOS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Bayesian ROC curve estimation under verification bias
Statistics in Medicine, 33(29), 5081–5096.
author keywords: binormal model; MAR assumption; posterior consistency; ROC curve; verification bias-correction
MeSH headings : Bayes Theorem; Bias; Computer Simulation; Data Interpretation, Statistical; Humans; Markov Chains; Models, Biological; Monte Carlo Method; Patient Selection; ROC Curve; Regression Analysis
TL;DR:
A new Bayesian approach for estimating an ROC curve based on continuous data following the popular semiparametric binormal model in the presence of verification bias is proposed and it is concluded that the estimator performs well in terms of accuracy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: August 6, 2018
2014 journal article
AlGaN/GaN field effect transistors functionalized with recognition peptides
Applied Physics Letters, 105(13).
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
A Coverage Criterion for Spaced Seeds and Its Applications to Support Vector Machine String Kernels and k-Mer Distances
JOURNAL OF COMPUTATIONAL BIOLOGY, 21(12), 947–963.
author keywords: spaced seeds; support vector machine; coverage; alignment-free distance
MeSH headings : Algorithms; Humans; Pattern Recognition, Automated; Sequence Alignment; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Software; Support Vector Machine
TL;DR:
This article shows how this coverage criterion can be directly measured by a full automaton-based approach, and illustrates how this criterion performs when compared with two other criteria frequently used, namely the single-hit and multiple-hit criteria, through correlation coefficients with the correct classification/the true distance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Sweetpotato grown from root pieces displays a significant genotype x environment interaction and yield instability
HortScience, 49(8), 984–990.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Response Diversity Can Increase Ecological Resilience to Disturbance in Coral Reefs
AMERICAN NATURALIST, 184(2), E16–E31.
author keywords: alternative stable states; coral bleaching; coral reefs; dynamical model; resilience; response diversity
MeSH headings : Animals; Anthozoa / growth & development; Coral Reefs; Ecosystem; Environment; Herbivory; Models, Theoretical; Seaweed / growth & development
TL;DR:
This work modeled coral-macroalgae interactions given either a resistant coral, a resilient coral, or both together and found that both corals benefit from the presence of each other in terms of total cover and resilience.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Rejoinder of "Dynamic treatment regimes: Technical challenges and applications"
Electronic Journal of Statistics, 8, 1312–1321.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Maintenance versus Maturation: Constructed Storm-Water Wetland’s Fifth-Year Water Quality and Hydrologic Assessment
Journal of Environmental Engineering, 140(10), 05014003.
author keywords: Storm water; Runoff; Sediment; Urban; Storm-water wetland; Nitrogen; Phosphorus; Maintenance; Wetland maturation; SCM; Green infrastructure
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: August 6, 2018
2014 journal article
Lymphoblastoid Cell Lines Models of Drug Response: Successes and Lessons from this Pharmacogenomic Model
CURRENT MOLECULAR MEDICINE, 14(7), 833–840.
author keywords: Cytotoxics; genetic association mapping; genome wide association analysis; lymphoplastoid cell lines; pharmacogenomics
MeSH headings : Cell Line, Transformed; Cost-Benefit Analysis; Genome-Wide Association Study / economics; Genome-Wide Association Study / methods; Humans; Lymphocytes / drug effects; Lymphocytes / metabolism; Models, Biological; Models, Genetic; Pharmacogenetics / economics; Pharmacogenetics / methods; Polymorphism, Single Nucleotide; RNA Interference; Reproducibility of Results; Translational Research, Biomedical / economics; Translational Research, Biomedical / methods
TL;DR:
The advantages, limitations, and opportunities for using lymphoblastoid cell lines (LCL) as a model system for human pharmacogenomic studies, including multivariate concentration response modeling, issues with multiple testing, and successful examples of the 'triangle model' to identify candidate variants are reviewed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
High Throughput Heuristics for Prioritizing Human Exposure to Environmental Chemicals
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 48(21), 12760–12767.
MeSH headings : Bayes Theorem; Biomarkers / urine; Child; Databases, Factual; Environmental Exposure / analysis; Environmental Pollutants / analysis; Environmental Pollutants / chemistry; Heuristics; Humans; Linear Models; Nutrition Surveys; United States
TL;DR:
This work used Bayesian methodology to infer ranges of exposure consistent with biomarkers identified in urine samples from the U.S. population by the National Health and Nutrition Examination Survey (NHANES).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Growth under field conditions affects lignin content and productivity in transgenic Populus trichocarpa with altered lignin biosynthesis
BIOMASS & BIOENERGY, 68, 228–239.
author keywords: Populus; Lignin; Field trial; Transgenic; Bioenergy
TL;DR:
The capacity to upregulate lignin in the event of environmental stress may have helped some low-lignin lines to survive and more research focused on promising construct lines in appropriate environmental conditions is needed to clarify if a significant reduction in lignIn can be achieved on a plantation scale, and whether that reduction will translate into increased efficiency of enzymatic hydrolysis.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2014 journal article
Genetic Characterization of Plasmid-Associated Triphenylmethane Reductase in Listeria monocytogenes
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(17), 5379–5385.
MeSH headings : Benzalkonium Compounds / metabolism; Benzalkonium Compounds / toxicity; Biotransformation; DNA Transposable Elements; Gene Order; Gentian Violet / metabolism; Gentian Violet / toxicity; Listeria monocytogenes / enzymology; Listeria monocytogenes / genetics; Listeria monocytogenes / isolation & purification; Oxidation-Reduction; Oxidoreductases / genetics; Oxidoreductases / metabolism; Plasmids; Rosaniline Dyes / metabolism; Rosaniline Dyes / toxicity; Trityl Compounds / metabolism
TL;DR:
A potential role of TMR as a previously unknown adaptive attribute for environmental persistence of L. monocytogenes is suggested.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Durations of Bone Consolidation and External Fixation After Distraction Osteogenesis in Dogs
VETERINARY SURGERY, 43(8), 903–911.
MeSH headings : Animals; Cohort Studies; Dogs; External Fixators / veterinary; Female; Fracture Fixation / instrumentation; Fracture Fixation / veterinary; Male; Osteogenesis, Distraction / methods; Osteogenesis, Distraction / veterinary; Osteotomy / instrumentation; Osteotomy / veterinary; Postoperative Complications; Radiography; Radius / diagnostic imaging; Radius / surgery; Recovery of Function; Retrospective Studies; Tibia / diagnostic imaging; Tibia / surgery; Treatment Outcome
TL;DR:
Wearing frames with low or moderate stiffness, the absence of mechanical complications, a larger distraction distance, and a larger bone size accelerated bone consolidation, and Optimizing these factors should accelerate bone consolidation and reduce the duration of external fixation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Double extreme on joint sets for Gaussian random fields
STATISTICS & PROBABILITY LETTERS, 92, 79–82.
author keywords: Gaussian random fields; Excursion probability; Excursion set; Euler characteristic
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Comment on "Dynamic treatment regimes: Technical challenges and applications"
Electronic Journal of Statistics, 8, 1290–1300.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Pathway-Guided Identification of Gene-Gene Interactions
ANNALS OF HUMAN GENETICS, 78(6), 478–491.
author keywords: Pathway analysis; gene-gene interactions; bio-knowledge-guided
MeSH headings : Computer Simulation; Epistasis, Genetic; Genotype; Humans; Linear Models; Models, Genetic; Polymorphism, Single Nucleotide; Principal Component Analysis; Regression Analysis
TL;DR:
A regression model with pathway‐guided regularization for detecting interactions among genes using the principal components to summarize the SNP‐SNP interactions between a gene pair, and an L1 penalty that incorporates adaptive weights based on biological guidance and trait supervision to identify important main and interaction effects is proposed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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