Works Published in 2022
Displaying works 41 - 60 of 92 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2022 article
POPEYE intercellular localization mediates cell-specific iron deficiency responses
Muhammad, D. S., Clark, N. M., Haque, S., Williams, C. M., Sozzani, R., & Long, T. A. (2022, August 3). PLANT PHYSIOLOGY, Vol. 8.
MeSH headings : Iron Deficiencies; Arabidopsis Proteins / metabolism; Gene Expression Regulation, Plant; Basic Helix-Loop-Helix Transcription Factors / metabolism; Arabidopsis / metabolism; Iron / metabolism; Plant Roots / genetics; Plant Roots / metabolism
TL;DR:
The findings indicate that PYE acts as a positive regulator of iron deficiency response by regulating iron bioavailability differentially across cells, which may trigger iron uptake from the surrounding rhizosphere and impact root energy metabolism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 13, 2022
2022 journal article
Live-cell fluorescence spectral imaging as a data science challenge
Biophysical Reviews.
TL;DR:
This review aims to provide both the experimental scientist and the data analyst with a straightforward description of the evolution of spectral unmixing algorithms for fluorescence live-cell imaging, and shows how the initial systems of linear equations used to determine the concentration of fluorophores in a pixel progressively evolved into matrix factorization, clustering, and deep learning approaches.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: July 11, 2022
2022 journal article
Cell cycle–independent integration of stress signals by Xbp1 promotes Non-G1/G0 quiescence entry
Journal of Cell Biology, 221(1).
MeSH headings : Cell Cycle; Cell Nucleus / metabolism; Cell Proliferation; Microfluidics; Repressor Proteins / metabolism; Saccharomyces cerevisiae / cytology; Saccharomyces cerevisiae / metabolism; Saccharomyces cerevisiae Proteins / metabolism; Signal Transduction; Stress, Physiological; Transcription Factors / metabolism
TL;DR:
This work uses machine learning and spectral imaging to show how the stress-activated transcriptional repressor Xbp1 can drive cellular quiescence—a reversible arrest of proliferation crucial for stress survival and development—even outside the G1 cell cycle stage.
(via Semantic Scholar)
rupress.org (publisher PDF)
Source: ORCID
Added: July 11, 2022
2022 journal article
Cdc14 spatiotemporally dephosphorylates Atg13 to activate autophagy during meiotic divisions
JOURNAL OF CELL BIOLOGY, 221(5).
MeSH headings : Adaptor Proteins, Signal Transducing / genetics; Adaptor Proteins, Signal Transducing / metabolism; Anaphase; Autophagy; Autophagy-Related Proteins / genetics; Autophagy-Related Proteins / metabolism; Cell Cycle Proteins / genetics; Cell Cycle Proteins / metabolism; Meiosis; Protein Tyrosine Phosphatases / genetics; Protein Tyrosine Phosphatases / metabolism; Saccharomyces cerevisiae Proteins / genetics; Saccharomyces cerevisiae Proteins / metabolism
TL;DR:
A meiosis-tailored mechanism of Cdc14 that governs autophagy is reported that stimulates Atg1 kinase activity and thus Autophagy at anaphases I and anaphase II to facilitate meiosis progression, meiosis exit, and sporulation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 11, 2022
2022 article
Plant Host Traits Mediated by Foliar Fungal Symbionts and Secondary Metabolites
Sandy, M., Bui, T. I., Aba, K. S., Ruiz, N., Paszalek, J., Connor, E. W., & Hawkes, C. V. (2022, June 17). MICROBIAL ECOLOGY, Vol. 6.
author keywords: Endophyte; Leaf; Metabolomics; Panicum virgatum; Switchgrass
TL;DR:
Examination of commonalities in how 16 fungal endophytes shift plant phenotypic traits such as growth and physiology is examined to inform ongoing efforts to develop metabolites as crop management tools, by identifying how associations with more beneficial components of the microbiome may be affected.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 18, 2022
2022 review
Deciphering the molecular basis of tissue-specific gene expression in plants: Can synthetic biology help?
[Review of ]. CURRENT OPINION IN PLANT BIOLOGY, 68.
author keywords: Tissue specificity; Gene expression; Synthetic biology; Transcription; factor; Epigenetics; Single cell; Transcriptomics; Logic gate; Promoter; Cis-regulatory element
MeSH headings : Computational Biology; Gene Expression; Gene Regulatory Networks / genetics; Plants / genetics; Plants / metabolism; Promoter Regions, Genetic / genetics; Synthetic Biology; Transcription Factors / metabolism
TL;DR:
Synthetic biology shows great promise not only as a means of testing candidate DNA motifs but also for establishing the general rules of nature driving promoter architecture and for the rational design of genetic circuits in research and agriculture to confer tissue-specific expression to genes or molecular pathways of interest.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 12, 2022
2022 journal article
Gene sdaB Is Involved in the Nematocidal Activity of Enterobacter ludwigii AA4 Against the Pine Wood Nematode Bursaphelenchus xylophilus
FRONTIERS IN MICROBIOLOGY, 5.
author keywords: sdaB; L-serine dehydratase; Enterobacter ludwigii; nematocidal activity; Bursaphelenchus xylophilus; pine wilt disease; methuosis
TL;DR:
Enterobacter ludwigii AA4, isolated from the root of maize, has powerful nematocidal activity against B. xylophilus and has significant potential to serve as an agent for the biological control of pine wilt disease caused by B.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: NC State University Libraries
Added: June 7, 2022
2022 article
Cdc14 plans autophagy for meiotic cell divisions
Feng, W., Arguello-Miranda, O., Qian, S., & Wang, F. (2022, May 28). AUTOPHAGY, Vol. 18.
author keywords: Atg1; Atg13; autophagy; Cdc14; meiosis; phosphatase; sporulation
MeSH headings : Adaptor Proteins, Signal Transducing / metabolism; Autophagy; Autophagy-Related Proteins / metabolism; Meiosis; Saccharomyces cerevisiae Proteins / metabolism
TL;DR:
In vitro and in vivo assays revealed that the conserved phosphatase Cdc14 stimulates autophagy initiation during meiotic divisions, specifically in anaphase I and II, when a subpopulation of active CDC14 relocates to the cytosol and interacts with phagophore assembly sites (PAS) triggering the dephosphorylation of Atg13 to stimulate Atg1 kinase activity and autophagic activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 6, 2022
2022 journal article
Phylogenomic conflict analyses in the apple genus Malus s.l. reveal widespread hybridization and allopolyploidy driving diversification, with insights into the complex biogeographic history in the Northern Hemisphere
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 64(5), 1020–1043.
author keywords: deep genome skimming; genomic discordance; historical biogeography; massive extinction; reticulate evolution; single-copy nuclear genes
MeSH headings : Fossils; Hybridization, Genetic; Malus / genetics; Phylogeny; Plastids
TL;DR:
The conflict analysis demonstrated that ILS, hybridization, and allopolyploidy could explain the widespread nuclear gene tree discordance and a historical biogeographic analysis integrating living and fossil data supported a widespread East Asian-western North American origin of Malus s.l.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: May 31, 2022
2022 journal article
Lessons for a SECURE Future: Evaluating Diversity in Crop Biotechnology Across Regulatory Regimes
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 10.
author keywords: crop biotechnology; SECURE rule; regulation; diversity trends; innovation; United States
TL;DR:
It is suggested that diversity in crop biotechnology does not follow a single trajectory dictated by the shifts in regulation, and outcomes of SECURE might be more varied and restrictive despite the revamped exemption categories.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 31, 2022
2022 journal article
Enhancing HR Frequency for Precise Genome Editing in Plants
FRONTIERS IN PLANT SCIENCE, 13.
author keywords: homologous recombination; homology-directed repair; gene targeting; donor template; programmable nucleases
TL;DR:
Various strategies implemented to increase the frequency of HDR in plant cells are summarized, including methods for targeting double-strand DNA breaks, optimizing donor sequences, altering plant DNA repair machinery, and environmental factors shown to influence HR frequency in plants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 31, 2022
2022 journal article
A viewpoint on ecological and evolutionary study of plant thermal performance curves in a warming world
AOB PLANTS, 14(3).
author keywords: Climate change; evolutionary ecology; genetic variation; plasticity; thermal adaptation; thermal niche; thermal performance curve; trade-off
TL;DR:
Recent plant studies that use a fitness-based TPC approach to test fundamental ecological and evolutionary hypotheses are described, some of which have uncovered key drivers of climate change responses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 31, 2022
2022 journal article
<p>Flavonols and dihydroflavonols inhibit the main protease activity of SARS-CoV-2 and the replication of human coronavirus 229E</p>
VIROLOGY, 571, 21–33.
author keywords: (+)-dihydrokaempferol; <p>(+)-dihydroquercetin (taxifolin)</p>; (+)-dihydromyricetin; Kaempferol; Quercetin; Myricentin; Isoquercitrin; Rutin; Flavan-3-ols
MeSH headings : COVID-19; Coronavirus 229E, Human / drug effects; Coronavirus 229E, Human / physiology; Coronavirus 3C Proteases / antagonists & inhibitors; Flavonols / pharmacology; Humans; Molecular Docking Simulation; SARS-CoV-2 / drug effects; Virus Replication / drug effects
TL;DR:
In vitro inhibition assays showed that seven available compounds effectively inhibited the SARS-CoV-2 Mpro activity and their IC50 values ranged from 0.125 to 12.9 µM, which indicates that these antioxidative flavonols and dihydroflavonols are promising candidates for curbing the two viruses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 23, 2022
2022 article
Single-well push-pull tests evaluating isobutane as a primary substrate for promoting in situ cometabolic biotransformation reactions
Rolston, H., Hyman, M., & Semprini, L. (2022, May 12). BIODEGRADATION, Vol. 5.
author keywords: Cometabolism; Push-pull tests; Isobutane; Isobutene; 1; 1-Dichloroethene; 1; 4-Dioxane
MeSH headings : Biodegradation, Environmental; Biotransformation; Butanes; Epoxy Compounds; Groundwater; Water Pollutants, Chemical / metabolism
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 23, 2022
2022 article
De novo phytosterol synthesis in animals
Michellod, D., Bien, T., Birgel, D., Jensen, M., Kleiner, M., Fearn, S., … Liebeke, M. (2022, April 22). (Vol. 4). Vol. 4.
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: May 19, 2022
2022 article
We Can Dance If We Want To (with Safety Measures)
Carson, S. (2022, April 26). MBIO, Vol. 13.
author keywords: COVID-19; SARS-CoV-2; Lindy Hop; public health; social gatherings; viral transmission
MeSH headings : COVID-19 / prevention & control; Dancing; Humans; North Carolina; SARS-CoV-2; Surveys and Questionnaires
TL;DR:
It appears that the majority of transmission occurred either through the result of individual interactions or activities outside the formal dance event rather than due to a buildup of airborne viral particles in the event space.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 16, 2022
2022 journal article
Protist Predation Influences the Temperature Response of Bacterial Communities
FRONTIERS IN MICROBIOLOGY, 13.
author keywords: predation; temperature; protistan bacterivory; bacterivores; aquatic microbiome; microbial respiration
TL;DR:
This study supports previous findings that temperature is an important driver of microbial communities but also demonstrates that the presence of a large predator can mediate these responses to warming.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: May 16, 2022
2022 article
Insights into acylation mechanisms: co-expression of serine carboxypeptidase-like acyltransferases and their non-catalytic companion paralogs
Yao, S., Liu, Y., Zhuang, J., Zhao, Y., Dai, X., Jiang, C., … Xia, T. (2022, May 7). PLANT JOURNAL, Vol. 5.
author keywords: tea; serine carboxypeptidase-like acyltransferase; flavan-3-ol gallates; co-expression; galloylation; non-catalytic companion paralog
MeSH headings : Acylation; Acyltransferases / metabolism; Carboxypeptidases / genetics; Carboxypeptidases / metabolism; Diospyros; Flavonoids; Phylogeny; Plants / metabolism; Polyphenols; Vitis / metabolism
TL;DR:
Findings show that the co‐expression of SCPL‐ATs and their NCCPs contributes to the acylation of flavan‐3‐ols in the plant kingdom.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 16, 2022
2022 journal article
Anthocyanins from muscadine (Vitis rotundifolia) grape fruit
CURRENT PLANT BIOLOGY, 30.
author keywords: Vitis rotundifolia; Muscadine; Grape; Polyphenols; Anthocyanins; Cyanin; Delphinin; Pelargonin
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 16, 2022
2022 article
Molecular and biochemical characterization of two 4-coumarate: CoA ligase genes in tea plant (Camellia sinensis)
Li, M., Guo, L., Wang, Y., Li, Y., Jiang, X., Liu, Y., … Xia, T. (2022, May 12). PLANT MOLECULAR BIOLOGY, Vol. 109.
author keywords: 4-Coumaric acid; CoA ligase; Flavonoids; Lignin; Metabolic engineering of phenylpropanoid; Stress
MeSH headings : Camellia sinensis / metabolism; Coenzyme A / genetics; Coenzyme A / metabolism; Coenzyme A Ligases / genetics; Coenzyme A Ligases / metabolism; Flavonoids / genetics; Gene Expression Regulation, Plant; Kinetics; Lignin / metabolism; Plant Proteins / genetics; Plant Proteins / metabolism; Tea
TL;DR:
Two 4-coumarate: CoA ligase genes in tea plant involved in phenylpropanoids biosynthesis and response to environmental stresses are reported, indicating the differences of Cs4CL1 and Cs 4CL2 in the phenyl Propanoid metabolism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: May 13, 2022
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