Works Published in 2010
Displaying works 181 - 200 of 248 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2010 journal article
The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii
BIOORGANIC & MEDICINAL CHEMISTRY, 18(2), 663–674.
author keywords: 2-Aminobenzimidazole; Chemical library synthesis; Antibiotic; Multidrug-resistant bacteria; Staphylococcus aureus; Acinetobacter baumannii
MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Benzimidazoles / chemical synthesis; Benzimidazoles / chemistry; Benzimidazoles / pharmacology; Drug Resistance, Multiple, Bacterial; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Molecular Conformation; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship
TL;DR:
These active 2-aminobenzimidazoles retain their antibiotic activity against several strains of multidrug-resistant Staphylococcus aureus and Acinetobacter baumannii when compared to susceptible strains.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Structure and Energetics of (C-60)(2)(2+) Conformers: Quantum Chemical Studies
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 31(2), 457–460.
author keywords: Ab initio quantum chemical methods; Fullerenes dimer dication; Conformer
www.ndsl.kr (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 review
Small Molecule Modifiers of the microRNA and RNA Interference Pathway
[Review of ]. AAPS JOURNAL, 12(1), 51–60.
author keywords: cancer; microRNA; RNA; RNA interference; small molecule
MeSH headings : Animals; Humans; MicroRNAs / antagonists & inhibitors; MicroRNAs / biosynthesis; RNA Interference / drug effects; RNA, Small Interfering / biosynthesis
TL;DR:
The activation of tumor-suppressive miRNAs and the inhibition of oncogenicMiRNAs by small molecules have the potential to provide a fundamentally new approach for the development of cancer therapeutics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Short-range magnetic order and temperature-dependent properties of cupric oxide
Journal of Physics. Condensed Matter, 22(4).
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
Quantitative top-down proteomics of SILAC labeled human embryonic stem cells
Journal of the American Society for Mass Spectrometry, 21(6), 879–889.
MeSH headings : Amino Acid Sequence; Animals; Arginine / chemistry; Arginine / metabolism; Carbon Isotopes; Cell Line; Embryonic Stem Cells / chemistry; Embryonic Stem Cells / metabolism; Humans; Isotope Labeling / methods; Lysine / chemistry; Lysine / metabolism; Mass Spectrometry / methods; Mice; Proteome / analysis; Proteomics / methods
TL;DR:
This study has confidently identified 11 proteins by accurate intact mass, MS/MS, and amino acid counting facilitated by SILAC labeling, which to the best of the authors' knowledge represents the first top-down analysis of hESCs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2010 journal article
Principles and Applications of the Photochemical Control of Cellular Processes
CHEMBIOCHEM, 11(1), 47–53.
author keywords: biological activity; cage compounds; chemical biology; light regulation; photochemistry
MeSH headings : Animals; Biological Phenomena / radiation effects; DNA / chemistry; Doxycycline / chemistry; Embryo, Mammalian; Mice; Phosphorothioate Oligonucleotides / chemistry; Photochemical Processes; Ultraviolet Rays
TL;DR:
The basic concepts and requirements of controlling biological (especially cellular) function with light, including photochemical regulation of biologically active molecules, are focused on.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
4. Quality Education
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Poly(lactic acid) brushes grow longer at lower temperatures
Journal of Polymer Science Part A: Polymer Chemistry, 48(15), 3362–3367.
author keywords: ring-opening polymerization; synthesis; interfaces
UN Sustainable Development Goal Categories
12. Responsible Consumption and Production
(Web of Science)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2010 journal article
Mixed Anion (Phosphate/Oxalate) Bonding to Iron(III) Materials
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(7), 2301–2308.
Contributors: F. Kizewski n, P. Boyle n, D. Hesterberg n & J. Martin n
TL;DR:
The critical role of the templating amine to mediate whether or not the iron(III) is reduced by the organic acid is demonstrated, which will be invaluable for the evaluation of complex environmental systems.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2010 journal article
Magneto-optical properties and charge-spin coupling in the molecular (2,3-dmpyH)(2)CuBr4 spin-ladder material
PHYSICAL REVIEW B, 81(5).
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Magnetic field induced quantum phase transition of the S=1/2 antiferromagnet K2NaCrO8
PHYSICAL REVIEW B, 81(6).
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Isoniazid-resistance conferring mutations in Mycobacterium tuberculosis KatG: Catalase, peroxidase, and INH-NADH adduct formation activities
Protein Science, 19(3), 458–474.
Contributors: C. Cade n, A. Dlouhy n, K. Medzihradszky *, S. Salas-Castillo* & R. Ghiladi n
author keywords: catalase-peroxidase; KatG; isoniazid; INH; heme; crosslink
MeSH headings : Antitubercular Agents / metabolism; Antitubercular Agents / pharmacology; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Catalase / chemistry; Catalase / genetics; Catalase / metabolism; Catalytic Domain; Drug Resistance, Bacterial / genetics; Humans; Isoniazid / metabolism; Isoniazid / pharmacology; Mutagenesis, Site-Directed; Mycobacterium tuberculosis / drug effects; Mycobacterium tuberculosis / enzymology; Mycobacterium tuberculosis / genetics; NAD / metabolism; Peroxidase / genetics; Protein Conformation; Tuberculosis, Multidrug-Resistant / microbiology
TL;DR:
The results demonstrate that residue location plays a critical role in determining INH‐resistance mechanisms associated with INH activation; however, different mutations at the same location can produce vastly different reactivities that are oxidant‐specific.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: August 6, 2018
2010 article
Interplay of Permanent Charge and Hydrophobicity in the Electrospray Ionization of Glycans
Walker, S. H., Papas, B. N., Comins, D. L., & Muddiman, D. C. (2010, August 1). ANALYTICAL CHEMISTRY, Vol. 82, pp. 6636–6642.
TL;DR:
The effectiveness of the incorporation of a permanent charge is studied and determined to hamper glycan analysis and a procedure for glycan hydrazone formation is optimized and outlined where a large number of variables were simultaneously analyzed using a fractional factorial design (FFD).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2010 article
Fluorescent dye adsorption on nanocarbon substrates through electrostatic interactions
DIAMOND AND RELATED MATERIALS, Vol. 19, pp. 234–237.
author keywords: Nanoparticle; Nanodiamond; Adsorption; Biomaterial; Surface modification
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Binding site on human immunoglobulin G for the affinity ligand HWRGWV
Journal of Molecular Recognition, 23(3), 271–282.
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
Analysis of kinamycin D-mediated DNA cleavage
TETRAHEDRON LETTERS, 51(11), 1455–1458.
TL;DR:
Kinamycin D is a potent antitumor antibiotic; however the biological mode of action is poorly understood, and recent efforts suggest the natural product is capable of generating reactive oxygen species under acidic pH to induce DNA damage in the presence of a reducing agent.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Syntheses, optical properties and electronic structures of copper(I) tantalates: Cu5Ta11O30 and Cu3Ta7O19
JOURNAL OF SOLID STATE CHEMISTRY, 183(4), 814–822.
author keywords: Copper tantalates; Solid-state synthesis; Flux synthesis; Optical properties
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2010 journal article
Synergistic Effects between Conventional Antibiotics and 2-Aminoimidazole-Derived Antibiofilm Agents
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54(5), 2112–2118.
MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Biofilms / drug effects; Calcium Chloride / pharmacology; Chlorides / pharmacology; Colistin / pharmacology; Drug Resistance, Bacterial; Drug Resistance, Multiple; Drug Synergism; Enterococcus faecium / drug effects; Erythrocytes / drug effects; Escherichia coli / drug effects; Humans; Imidazoles / chemistry; Imidazoles / pharmacology; Magnesium / pharmacology; Manganese Compounds / pharmacology; Methicillin-Resistant Staphylococcus aureus / drug effects; Novobiocin / pharmacology; Staphylococcus epidermidis / drug effects; Tobramycin / pharmacology; Triazoles / pharmacology
TL;DR:
The synergistic effect between a 2-aminoimidazole/triazole conjugate and antibiotics toward dispersing preestablished biofilms, culminating with a 3-orders-of-magnitude increase of biofilm dispersion toward Staphylococcus aureus biofilmms is reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Reversible light switching of cell signalling by genetically encoded protein dimerization
Chembiochem, 11(3), 301–303.
MeSH headings : Animals; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Cell Membrane / chemistry; Cell Membrane / metabolism; Light; Luminescent Proteins / chemistry; Luminescent Proteins / metabolism; Mice; NIH 3T3 Cells; Phycobilins / chemistry; Phycocyanin / chemistry; Phytochrome B / chemistry; Phytochrome B / genetics; Phytochrome B / metabolism; Protein Multimerization; Protein Structure, Tertiary; Signal Transduction
TL;DR:
This work has shown that a light-switchable transcriptional activator was constructed from a protein–protein interaction module in the phytochrome signalling network of the plant Arabidopsis thaliana, which enables the application of light toward the genetically encoded, reversible photoregulation of a cellular event.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
Physical Properties of AlGaN/GaN Heterostructures Grown on Vicinal Substrates
JOURNAL OF ELECTRONIC MATERIALS, 39(5), 504–516.
author keywords: GaN; vicinal surfaces
Source: Web Of Science
Added: August 6, 2018
2010 journal article
New Insights into the Role of Distal Histidine Flexibility in Ligand Stabilization of Dehaloperoxidase-Hemoglobin from Amphitrite ornata
BIOCHEMISTRY, 49(9), 1903–1912.
MeSH headings : Animals; Enzyme Stability; Ferric Compounds / chemistry; Hemoglobins / antagonists & inhibitors; Hemoglobins / chemistry; Hemoglobins / metabolism; Histidine / chemistry; Ligands; Magnetic Resonance Spectroscopy; Peroxidases / antagonists & inhibitors; Peroxidases / chemistry; Peroxidases / metabolism; Polychaeta / enzymology; Protein Binding; Protein Conformation; Spectrophotometry; Spectrum Analysis, Raman; Substrate Specificity
TL;DR:
The two conformations of His55 in equilibrium at room temperature provide a level of control that permits the distal histidine to act as both the acid-base catalyst in the peroxidase mechanism and the stabilizing amino acid for exogenous heme-coordinated ligands.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
