Works Published in 2018

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Displaying works 41 - 60 of 252 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2018 journal article

Dipole Effects on Electron Transfer are Enormous

Angewandte Chemie International Edition, 57(38), 12365–12369.

author keywords: charge transfer; dipoles; electron transfer; kinetics; Rehm-Weller equation
TL;DR: It is revealed that dipoles can substantially alter the ET driving force for low solvent polarity, which accounts for these unique trends. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: ORCID, Crossref
Added: January 16, 2022

2018 journal article

Cover Picture: Dipole Effects on Electron Transfer are Enormous (Angew. Chem. Int. Ed. 38/2018)

Angewandte Chemie International Edition, 57(38), 12179–12179.

Source: ORCID
Added: January 16, 2022

2018 article

Synthesis and Biological Evaluation of the Antimicrobial Natural Product Lipoxazolidinone A

Mills, J. J., Robinson, K. R., Zehnder, T. E., & Pierce, J. G. (2018, April 9).

By: J. Mills, K. Robinson, T. Zehnder & J. Pierce n

UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: October 21, 2021

2018 speech

Beauty through simplicity – functionalized aptamers for on-site small-molecule detection

Invited talk presented at the University of Notre Dame, South Bend, Indiana.

By: Y. Xiao

Event: at University of Notre Dame, South Bend, Indiana on September 17, 2018

Source: NC State University Libraries
Added: July 27, 2021

2018 conference paper

Aptamer-based Assays for On-site Drug Detection

Presented at the Pittcon 2018, Orlando, Florida.

By: Y. Xiao

Event: Pittcon 2018 at Orlando, Florida on February 26 - March 1, 2018

Source: NC State University Libraries
Added: July 27, 2021

2018 conference paper

Rapid and sensitive detection of small-molecule targets via enzyme-assisted target recycling based on cooperative binding split aptamers

Presented at the Pittcon 2018, Orlando, Florida.

By: H. Yu, J. Canoura, B. Guntupalli, X. Lou & Y. Xiao

Event: Pittcon 2018 at Orlando, Florida on February 26 - March 1, 2018

Source: NC State University Libraries
Added: July 27, 2021

2018 conference paper

Utilizing nuclease screening of ligand-aptamer complexes to enhance specificity of an aptamer-based cocaine assay

Presented at the 2017 Society of Forensic Toxicologists-International Association of Forensic Toxicologists (SOFT-TIAFT) Joint Meeting, Boca Raton, Florida.

By: Z. Wang, J. Canoura, H. Yu & Y. Xiao

Event: 2017 Society of Forensic Toxicologists-International Association of Forensic Toxicologists (SOFT-TIAFT) Joint Meeting at Boca Raton, Florida on January 7-11, 2018

Source: NC State University Libraries
Added: July 27, 2021

2018 report

Materials and methods for rapid visualization of NAD(P)H

(Patent No. US10000790B2).

By: P. Liang, H. Yu & Y. Xiao

Source: NC State University Libraries
Added: July 27, 2021

2018 journal article

Dithiothreitol-Regulated Coverage of Oligonucleotide-Modified Gold Nanoparticles To Achieve Optimized Biosensor Performance

ACS Applied Materials & Interfaces, 10(4), 4233–4242.

By: P. Liang*, J. Canoura*, H. Yu*, O. Alkhamis* & Y. Xiao*

author keywords: gold nanoparticles; DNA surface coverage; dithiothreitol; enzyme-assisted target recycling; DNA detection; cocaine detection
MeSH headings : Biosensing Techniques; Colorimetry; Dithiothreitol; Gold; Metal Nanoparticles
TL;DR: This work develops a single-step assay utilizing dithiothreitol (DTT) to fine-tune the surface coverage of DNA-modified AuNPs, and demonstrates the effects of surface coverage on AuNP-based sensors using DTT-regulated DNA- modified AuNBP. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: July 11, 2021

2018 journal article

Sensitive Detection of Small-Molecule Targets Using Cooperative Binding Split Aptamers and Enzyme-Assisted Target Recycling

Analytical Chemistry, 90(3), 1748–1758.

By: H. Yu*, J. Canoura*, B. Guntupalli*, O. Alkhamis* & Y. Xiao*

MeSH headings : Aptamers, Nucleotide / chemistry; Biosensing Techniques / methods; Colorimetry / methods; DNA / chemistry; Dehydroepiandrosterone Sulfate / analysis; Exodeoxyribonucleases / chemistry; Gold / chemistry; Limit of Detection; Metal Nanoparticles / chemistry; Nucleic Acid Amplification Techniques / methods
TL;DR: An instrument-free colorimetric assay employing EATR-mediated aggregation of CBSA-modified gold nanoparticles for the visual detection of low-micromolar concentrations of cocaine is developed and it is believed that such assays should prove valuable for detecting small-molecule targets in diverse fields. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: July 11, 2021

2018 journal article

In vitro isolation of small-molecule-binding aptamers with intrinsic dye-displacement functionality

Nucleic Acids Research, 46(8), e43–e43.

By: H. Yu*, W. Yang*, O. Alkhamis*, J. Canoura*, K. Yang* & Y. Xiao*

MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / genetics; Aptamers, Nucleotide / isolation & purification; Base Sequence; Benzodioxoles / analysis; Biosensing Techniques / methods; Carbocyanines / chemistry; Colorimetry / methods; Coloring Agents / chemistry; DNA / chemistry; DNA / genetics; Molecular Structure; Pyrrolidines / analysis; SELEX Aptamer Technique / methods; Synthetic Cathinone
TL;DR: A simple strategy for directly isolating signal-reporting aptamers in vitro through systematic evolution of ligands by exponential enrichment that transduce binding events into a detectable change of absorbance via target-induced displacement of a small-molecule dye. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: July 11, 2021

2018 journal article

Introducing structure-switching functionality into small-molecule-binding aptamers via nuclease-directed truncation

Nucleic Acids Research, 46(13), e81–e81.

By: Z. Wang*, H. Yu*, J. Canoura*, Y. Liu*, O. Alkhamis*, F. Fu*, Y. Xiao*

MeSH headings : Adenosine Triphosphate / analysis; Aptamers, Nucleotide / chemistry; Cocaine / analysis; Exodeoxyribonucleases; Mutation; Spectrometry, Fluorescence
TL;DR: The authors' Exo III-digestion method should be applicable for the generation of structure-switching aptamers from other TWJ- or stem–loop-containing small-molecule-binding aptamer, greatly simplifying thegeneration of functionalized sensor elements for folding-based aptasensors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: July 11, 2021

2018 journal article

No Structure-Switching Required: A Generalizable Exonuclease-Mediated Aptamer-Based Assay for Small-Molecule Detection

Journal of the American Chemical Society, 140(31), 9961–9971.

By: J. Canoura*, Z. Wang*, H. Yu*, O. Alkhamis*, F. Fu* & Y. Xiao*

MeSH headings : Aptamers, Nucleotide / chemistry; Calorimetry / methods; Cocaine / chemistry; DNA / chemistry; Exodeoxyribonucleases / chemistry; Fluorescent Dyes / chemistry
TL;DR: It is shown that the digestion of aptamers by exonuclease III can likewise be inhibited upon binding of small-molecule targets and exploited for the first time to achieve sensitive, label-free small-Molecule detection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: July 11, 2021

2018 conference paper

Oxime ligation via in situ oxidation of N-phenylglycinyl peptides

Guthrie, Q. A., & Proulx, C. (2018, February 11). Presented at the Chemistry and Biology of Peptides Gordon Research Conference (GRC), Ventura, California.

By: Q. Guthrie & C. Proulx

Event: Chemistry and Biology of Peptides Gordon Research Conference (GRC) at Ventura, California on February 11-16, 2018

Source: NC State University Libraries
Added: March 4, 2021

2018 speech

Teaching and Learning through Exploration and Discovery

Martin, J., & Nock, K. A. (2018, November). Presented at the National Science Teachers Association, Charlotte, NC.

By: J. Martin & K. Nock

Event: National Science Teachers Association at Charlotte, NC

Source: NC State University Libraries
Added: March 4, 2021

2018 report

K-Space Algorithmic Reconstruction (KAREN)

In Mantid [Software]. https://docs.mantidproject.org/nightly/algorithms/DeltaPDF3D.html

By: J. Martin, J. Weng, R. Whitfield, C. Hoffman & F. Ye

Source: NC State University Libraries
Added: March 4, 2021

2018 journal article

Parawasserstoff-basierte Hyperpolarisierung für die Biomedizin

Angewandte Chemie, 130(35), 11310–11333.

By: J. Hövener*, A. Pravdivtsev*, B. Kidd*, C. Bowers*, S. Glöggler*, K. Kovtunov*, M. Plaumann*, R. Katz-Brull* ...

Sources: Crossref, ORCID
Added: February 6, 2021

2018 journal article

Determination of the Acid Dissociation Constant of a Phenolic Acid by High Performance Liquid Chromatography: An Experiment for the Upper Level Analytical Chemistry laboratory

Journal of Chemical Education, 95(2), 310–314.

By: G. Rabah n

author keywords: Upper-Division Undergraduate; Analytical Chemistry; Inquiry-Based/Discovery Learning; Hands-On Learning/Manipulatives; Chromatography; HPLC
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: January 26, 2021

2018 journal article

Local μ-Opioid Receptor Antagonism Blunts Evoked Phasic Dopamine Release in the Nucleus Accumbens of Rats

ACS Chemical Neuroscience, 10(4), 1935–1940.

By: A. Gómez-A*, T. Shnitko*, H. Barefoot*, E. Brightbill*, L. Sombers n, S. Nicola*, D. Robinson*

author keywords: mu-opioid receptor; dopamine; accumbens; phasic; electrochemistry; local infusion
MeSH headings : Animals; Dopamine / metabolism; Dopamine Uptake Inhibitors / administration & dosage; Dose-Response Relationship, Drug; Infusions, Intraventricular; Male; Narcotic Antagonists / administration & dosage; Nucleus Accumbens / drug effects; Nucleus Accumbens / metabolism; Peptide Fragments / administration & dosage; Rats; Rats, Long-Evans; Receptors, Opioid, mu / antagonists & inhibitors; Receptors, Opioid, mu / metabolism; Somatostatin / administration & dosage
Source: Crossref
Added: January 18, 2021

2018 journal article

NMDA Receptor-Dependent Cholinergic Modulation of Mesolimbic Dopamine Cell Bodies: Neurochemical and Behavioral Studies

ACS Chemical Neuroscience, 10(3), 1497–1505.

By: M. Spanos n, X. Xie n, J. Gras-Najjar n, S. White n & L. Sombers n

author keywords: Glutamate; acetylcholine; dopamine; sensory stimuli; ventral tegmental area
MeSH headings : Animals; Cell Body / drug effects; Cell Body / metabolism; Cholinergic Agonists / administration & dosage; Dopamine / metabolism; Male; Microinjections / methods; N-Methylaspartate / administration & dosage; Photic Stimulation / methods; Psychomotor Performance / drug effects; Psychomotor Performance / physiology; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate / agonists; Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors; Receptors, N-Methyl-D-Aspartate / metabolism; Ventral Tegmental Area / drug effects; Ventral Tegmental Area / metabolism
TL;DR: It is suggested that acetylcholine and glutamate synergistically act at dopamine cells in the VTA to modulate VTA-NAc shell dopaminergic output, and this underlies motivation to lever press for a motivationally neutral visual stimulus. (via Semantic Scholar)
Source: Crossref
Added: January 18, 2021

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