Works Published in 2018
Displaying works 61 - 80 of 252 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2018 journal article
Characterization of a Multiple-Scan-Rate Voltammetric Waveform for Real-Time Detection of Met-Enkephalin
ACS Chemical Neuroscience, 10(4), 2022–2032.
author keywords: carbon fiber; opioid; chromaffin cell; dopamine; cyclic voltammetry; microelectrode; FSCV
MeSH headings : Adrenal Glands / chemistry; Adrenal Glands / metabolism; Animals; Electrochemical Techniques / methods; Enkephalin, Methionine / analysis; Enkephalin, Methionine / metabolism; Male; Microinjections / methods; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Substantia Nigra / chemistry; Substantia Nigra / metabolism
TL;DR:
This work evaluated the waveform parameters to increase sensitivity to methionine-enkephalin (M-ENK), an endogenous opioid neuropeptide implicated in pain, stress, and reward circuits and demonstrates how voltammetric waveforms can be customized to enhance detection of specific target analytes, broadly speaking.
(via Semantic Scholar)
pubs.acs.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: January 18, 2021
2018 journal article
Reducing Data Density in Fast-Scan Cyclic Voltammetry Measurements of Dopamine Dynamics
Journal of The Electrochemical Society, 165(12), G3042–G3050.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID
Added: January 18, 2021
2018 journal article
15N4-1,2,4,5-tetrazines as potential molecular tags: Integrating bioorthogonal chemistry with hyperpolarization and unearthing para-N2
Science Advances, 4(3), eaar2978.
Contributors: J. Bae *, Z. Zhou *, T. Theis* , W. Warren * & Q. Wang *
TL;DR:
This work suggests great potential of 15N4-1,2,4,5-tetrazines as molecular tags in HP-MR imaging (HP-MRI) and supports the production of hyperpolarized para-15N2 gas, a biologically and medically innocuous gas with great potential for HP-MRI.
(via Semantic Scholar)
Sources: ORCID, Crossref
Added: January 12, 2021
2018 journal article
Parahydrogen-Based Hyperpolarization for Biomedicine
Angewandte Chemie International Edition, 57(35), 11140–11162.
Contributors: J. Hövener *, A. Pravdivtsev *, B. Kidd*, C. Bowers *, S. Glöggler *, K. Kovtunov *, M. Plaumann *, R. Katz-Brull *
author keywords: hyperpolarization; magnetic resonance imaging; NMR spectroscopy; parahydrogen
TL;DR:
Considerable progress has been made in the past decade in the area of pH2 -based hyperpolarization techniques for biomedical applications, covering the areas of spin physics, catalysis, instrumentation, preparation of the contrast agents, and applications.
(via Semantic Scholar)
Sources: ORCID, Crossref
Added: January 12, 2021
2018 journal article
Secondary Social Studies Teachers’ Experiences Planning and Implementing Inquiry Using the Inquiry Design Model
The Clearing House: A Journal of Educational Strategies, Issues and Ideas, 91(4-5), 193–200.
Sources: Crossref, ORCID
Added: December 17, 2020
2018 journal article
Exploring How an Elementary Teacher Plans and Implements Social Studies Inquiry
The Social Studies, 109(2), 85–100.
UN Sustainable Development Goal Categories
4. Quality Education
(OpenAlex)
Sources: Crossref, ORCID
Added: December 17, 2020
2018 journal article
Rhodium at the Chemistry-Biology Interface
Dalton Transactions.
MeSH headings : Animals; Catalysis; Chemistry, Pharmaceutical; DNA / drug effects; Humans; Molecular Structure; Organometallic Compounds / chemical synthesis; Organometallic Compounds / chemistry; Organometallic Compounds / pharmacology; Proteins / antagonists & inhibitors; Proteins / metabolism; Rhodium / chemistry; Rhodium / pharmacology; Structure-Activity Relationship
TL;DR:
A brief review of recent advances in the use of rhodium complexes in biological contexts, including medicinal chemistry, protein science, and chemical biology, highlights both structure- and reactivity-driven approaches to biological probes and discusses how coordination environment affects molecular properties in a biological environment.
(via Semantic Scholar)
Source: ORCID
Added: December 16, 2020
2018 journal article
A Naturally Encoded Dipeptide Handle for Bioorthogonal Chan-Lam Coupling
Angewandte Chemie International Edition, 57(15), 4015–4019.
author keywords: bioinorganic chemistry; copper; protein modifications; pyroglutamate; transition metals
TL;DR:
It is reported that pyroglutamate amide N-H bonds exhibit bioorthogonal copper-catalyzed Chan-Lam coupling at pyrogLutamate-histidine dipeptide sequences, allowing specific bioconjugation at a minimalist dipePTide tag.
(via Semantic Scholar)
Source: ORCID
Added: December 16, 2020
2018 journal article
A Three-Component Organometallic Tyrosine Bioconjugation
Angewandte Chemie International Edition, 57(11), 2827–2830.
author keywords: arenes; bioinorganic chemistry; protein modifications; rhodium; transition metals
MeSH headings : Animals; Boronic Acids / chemical synthesis; Boronic Acids / chemistry; Catalysis; Cattle; Cell Line; Fluorescent Dyes / chemical synthesis; Fluorescent Dyes / chemistry; Humans; Models, Molecular; Oxidation-Reduction; Peptides / chemical synthesis; Peptides / chemistry; Proteins / chemical synthesis; Proteins / chemistry; Rhodium / chemistry; Salts / chemistry; Tyrosine / chemical synthesis; Tyrosine / chemistry
TL;DR:
An organometallic bioconjugation, employing rhodium(III) salts, to link boronic acids with tyrosine residues by an arene complex is described, allowing incorporation of useful functionalities, such as affinity handles or fluorophores.
(via Semantic Scholar)
Source: ORCID
Added: December 16, 2020
2018 journal article
Protoporphyrin-IX conjugated cellulose nanofibers that exhibit high antibacterial photodynamic inactivation efficacy
Nanotechnology, 29(26), 265601.
author keywords: cellulose; antibacterial; photodynamic; photosensitizer; E. coli; S. aureus
MeSH headings : Anti-Bacterial Agents / pharmacology; Calorimetry, Differential Scanning; Cellulose / chemistry; Escherichia coli / drug effects; Escherichia coli / ultrastructure; Microbial Sensitivity Tests; Microbial Viability / drug effects; Nanofibers / chemistry; Nanofibers / ultrastructure; Photochemotherapy; Protoporphyrins / pharmacology; Reactive Oxygen Species / metabolism; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Staphylococcus aureus / drug effects; Staphylococcus aureus / ultrastructure; Stress, Mechanical; Thermogravimetry
TL;DR:
The conjugation strategy employed here provides a scalable, facile and efficient route to creating nanofibrous materials from natural polymers with a high photosensitizer loading, enabling the use of commercially-available neutral porphyrin photosensiters, such as PPIX, in the design and synthesis of potent anti-infective nanomaterials.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: ORCID, Crossref
Added: December 15, 2020
2018 journal article
Synthesis and Biological Evaluation of the Antimicrobial Natural Product Lipoxazolidinone A
Angewandte Chemie, 130(28), 8818–8822.
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: December 15, 2020
2018 chapter
Rhodium(II)-Catalyzed Cyclopropanation
In Rhodium Catalysis in Organic Synthesis: Methods and Reactions. https://www.wiley.com/en-us/Rhodium+Catalysis+in+Organic+Synthesis%3A+Methods+and+Reactions-p-9783527811892
Source: ORCID
Added: December 15, 2020
2018 journal article
Substrate Conformation Correlates with the Outcome of Hyoscyamine 6β-Hydroxylase Catalyzed Oxidation Reactions
Journal of the American Chemical Society, 140(24), 7433–7436.
Contributors: R. Ushimaru *, M. Ruszczycky*, W. Chang* , F. Yan *, Y. Liu* & H. Liu *
MeSH headings : Atropine Derivatives / chemistry; Catalysis; Cyclization; Hydroxylation; Mixed Function Oxygenases / chemistry; Models, Chemical; Molecular Conformation; Oxidation-Reduction
TL;DR:
Results indicate that hydroxyl rebound is unlikely to take place during the cyclization reaction and that the hydroxyase versus oxidative cyclase activity of H6H is correlated with the presence of an exo-hydroxy group having syn-periplanar geometry with respect to the adjacent H atom to be abstracted.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 11, 2020
2018 journal article
Installation of the Ether Bridge of Lolines by the Iron- and 2-Oxoglutarate-Dependent Oxygenase, LolO: Regio- and Stereochemistry of Sequential Hydroxylation and Oxacyclization Reactions
Biochemistry, 57(14), 2074–2083.
Contributors: J. Pan*, M. Bhardwaj*, B. Zhang *, W. Chang* , C. Schardl *, C. Krebs *, R. Grossman *, J. Martin Bollinger *
MeSH headings : Alkaloids / chemistry; Epichloe / enzymology; Fungal Proteins / chemistry; Iron / chemistry; Ketoglutaric Acids / chemistry; Oxygenases / chemistry
TL;DR:
The findings delineate the pathway to an important class of natural insecticides and lay the foundation for mechanistic dissection of the chemically challenging oxacyclization reaction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, ORCID
Added: December 11, 2020
2018 journal article
Synthesis of Quaternary-Substituted Thiazolines via Halocyclization of S-Allyl Thioimidate Salts
The Journal of Organic Chemistry, 83(1), 12–22.
TL;DR:
An efficient synthesis of S-allyl thioimidate hydrobromide salts via coupling of thioamides with allyl bromide derivatives is described, providing a variety of substituted alkyl- and arylthiazolines.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, ORCID
Added: December 11, 2020
2018 conference paper
Competition between dynamic and structural disorder in a doped triangular antiferromagnet RbFe(MoO<inf>4</inf>)<inf>2</inf>
Journal of Physics: Conference Series, 969(1).
Contributors: A. Smirnov* , T. Soldatov *, O. Petrenko *, A. Takata *, T. Kida *, M. Hagiwara *, M. Zhitomirsky*, A. Shapiro*
Source: ORCID
Added: December 4, 2020
2018 journal article
Enhancing Sensitivity of Double Electron-Electron Resonance (DEER) by Using Relaxation-Optimized Acquisition Length Distribution (RELOAD) Scheme
Journal of Magnetic Resonance, 12, 115–126.
author keywords: PELDOR; DEER; EPR; Spin-labeling; Dipolar spectroscopy; Distance measurements
MeSH headings : Algorithms; Electron Spin Resonance Spectroscopy / methods; Gramicidin / chemistry; Leptospira; Models, Chemical; Models, Molecular; Rhodopsin / chemistry; Sensitivity and Specificity; Signal-To-Noise Ratio; Spin Labels
TL;DR:
A novel albeit simple approach to improve DEER sensitivity and decrease data acquisition time by introducing the signal acquisition scheme based on RELaxation Optimized Acquisition (Length) Distribution (DEER-RELOAD).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: December 4, 2020
2018 journal article
Efficient CO2 Removal for Ultra‐Pure CO Production by Two Hybrid Ultramicroporous Materials
Angewandte Chemie.
Source: ORCID
Added: December 1, 2020
2018 journal article
Development of Transcription Factor-Based Designer Macrolide Biosensors for Metabolic Engineering and Synthetic Biology
ACS Synthetic Biology, 7(1), 227–239.
MeSH headings : Actinobacteria / drug effects; Actinobacteria / growth & development; Binding Sites; Biosensing Techniques; Directed Molecular Evolution; Erythromycin / biosynthesis; Erythromycin / pharmacology; Ligands; Macrolides / metabolism; Metabolic Engineering; Molecular Dynamics Simulation; Mutagenesis; Protein Structure, Tertiary; Synthetic Biology / methods; Transcription Factors / chemistry; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR:
It is shown that the promiscuous macrolide sensing transcription factor MphR is a powerful platform for engineering variants with tailored properties that displayed improved sensitivity toward erythromycin, tailored the inducer specificity, and significantly improved sensitivity to macrolides that were very poor inducers of the wild-type MphC biosensor.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID
Added: November 29, 2020
2018 journal article
Conrad Bessant (Ed.): Proteome informatics
Analytical and Bioanalytical Chemistry, 410(14), 3231–3233.
TL;DR:
The book Proteome informatics describes the bioinformatics of proteome analyses in the very context of proteomics workflows, highlighting the essential fund of knowledge that will enable the proteomics expert to exploit and construct algorithms that can effectively interrogate gigabytes of data.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: November 29, 2020
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