Works Published in 2012

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Displaying works 1 - 20 of 223 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2012 journal article

Strained ruthenium complexes are potent light-activated anticancer agents

Journal of the American Chemical Society, 134(20), 8324–8327.

By: B. Howerton*, D. Heidary* & E. Glazer*

Contributors: B. Howerton*, D. Heidary* & E. Glazer*

TL;DR: The use of intramolecular strain may be applied as a general paradigm to develop light-activated ruthenium complexes for PDT applications to display potencies superior to cisplatin against 3D tumor spheroids. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: November 30, 2023

2012 journal article

Light-activated ruthenium complexes photobind DNA and are cytotoxic in the photodynamic therapy window

Chemical Communications, 48(77), 9649–9651.

By: E. Wachter*, D. Heidary*, B. Howerton*, S. Parkin* & E. Glazer*

Contributors: E. Wachter*, D. Heidary*, B. Howerton*, S. Parkin* & E. Glazer*

TL;DR: Structural analysis shows that distortion facilitates the photochemistry, and gel shift and cytotoxicity studies prove the compounds act as anti-cancer photodynamic therapy (PDT) agents in the tissue penetrant region. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: November 30, 2023

2012 journal article

One bipyridine and triple advantages: tailoring ancillary ligands in ruthenium complexes for efficient sensitization in dye solar cells

Journal of Materials Chemistry, 22(36), 18757.

Contributors: M. Chandrasekharam*, M. Reddy*, S. Singh*, B. Priyanka*, K. Bhanuprakash*, M. Kantam*, A. Islam*, L. Han*

UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: ORCID
Added: March 15, 2023

2012 journal article

Synthesis of new 4-thiazolidinone-, pyrazoline-, and isatin-based conjugates with promising antitumor activity

Journal of Medicinal Chemistry, 55(20), 8630–8641.

By: D. Havrylyuk*, B. Zimenkovsky*, O. Vasylenko*, A. Gzella* & R. Lesyk*

Contributors: D. Havrylyuk*, B. Zimenkovsky*, O. Vasylenko*, A. Gzella* & R. Lesyk*

MeSH headings : Antineoplastic Agents / chemical synthesis; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Isatin / analogs & derivatives; Isatin / chemical synthesis; Isatin / chemistry; Isatin / pharmacology; Pyrazoles / chemical synthesis; Pyrazoles / chemistry; Pyrazoles / pharmacology; Structure-Activity Relationship; Thiazolidines / chemical synthesis; Thiazolidines / chemistry; Thiazolidines / pharmacology
TL;DR: The most effective anticancer compound 10 was found to be active with mean GI₅₀ and TGI values of 0.071 μM and 0.76 μM, respectively and demonstrated the highest antiproliferative influence on the non-small-cell lung cancer cell line HOP-92. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: January 23, 2023

2012 journal article

Study of molecular mechanisms of proapoptotic action of novel heterocyclic 4-thiazolidone derivatives

Biopolymers and Cell, 28(2), 121–128.

By: R. Panchuk*, V. Chumak*, M. Fil*, D. Havrylyuk*, B. Zimenkovsky*, R. Lesyk*, R. Stoika*

Contributors: R. Panchuk*, V. Chumak*, M. Fil*, D. Havrylyuk*, B. Zimenkovsky*, R. Lesyk*, R. Stoika*

TL;DR: Structural-functional relationships between the presence of specific side groups in novel 4-thiazolidones and the signaling apoptotic pathways induced by these compounds have been established and allow designing new, «hybrid» compounds which can simultaneously induce more than one apoptotic pathway in tumor cells. (via Semantic Scholar)
Source: ORCID
Added: January 23, 2023

2012 journal article

In vitro cytotoxicity of nitroxyl radicals with respect: To tumor and diploid human cells and estimation of their antiviral activity

Antibiotiki i Khimioterapiya, 57(1-2), 3–12. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874999709&partnerID=MN8TOARS

By: I. Kirilyuk, V. Svyatchenko, D. Morozov, E. Kazachinskaya, N. Kiselev, S. Bakunova, M. Voinov, V. Loktev, I. Grigoryev

Contributors: I. Kirilyuk, V. Svyatchenko, D. Morozov, E. Kazachinskaya, N. Kiselev, S. Bakunova, M. Voinov, V. Loktev, I. Grigoryev

Source: ORCID
Added: October 25, 2022

2012 conference paper

Growth and Structural Characterization of Alkanethiol Self-Assembled Monolayers

Toney, B. J., Cooley, J. A., Gillete, W. M., Weigel, E. A., & Martin, M. R. (2012, November). Presented at the 64th Southeastern Regional Meeting of the American Chemical Society, Raleigh, NC.

By: B. Toney, J. Cooley, W. Gillete, E. Weigel & M. Martin

Event: 64th Southeastern Regional Meeting of the American Chemical Society at Raleigh, NC

Source: NC State University Libraries
Added: June 25, 2022

2012 journal article

Rotational dynamics of cargos at pauses during axonal transport

Nature Communications, 3(1).

By: Y. Gu*, W. Sun*, G. Wang n, K. Jeftinija*, S. Jeftinija* & N. Fang*

MeSH headings : Animals; Axonal Transport; Axons / chemistry; Axons / metabolism; Biological Transport, Active; Dyneins / metabolism; Endocytosis; Kinesins / metabolism; PC12 Cells; Rats; Rotation
TL;DR: First-time observations of cargo's rotational dynamics provide new insights on how kinesin and dynein motors take the cargo through the alternating stages of active directional transport and pause, with a temporal resolution of 2 ms. (via Semantic Scholar)
Source: Crossref
Added: May 1, 2022

2012 journal article

Electrophoretic Migration and Axial Diffusion of Individual Nanoparticles in Cylindrical Nanopores

The Journal of Physical Chemistry C, 116(34), 18460–18468.

By: R. Han*, G. Wang*, S. Qi*, C. Ma* & E. Yeung*

TL;DR: The electrophoretic mobilities and the diffusion coefficients of polystyrene nanoparticles were both substantially smaller compared to bulk solution independent of particle size or pore diameter, implying that the apparent solution viscosity in nanodomains is anomalous. (via Semantic Scholar)
Source: Crossref
Added: May 1, 2022

2012 journal article

Deciphering Orientation and Rotational Information of Cargoes at Pauses During Axonal Transport

Biophysical Journal, 102(3), 38a–39a.

TL;DR: The lateral and rotational motions of cargos during directional transport and pausing stages are elucidated, and their relationship with motor protein competition and regulation is discussed. (via Semantic Scholar)
Source: Crossref
Added: May 1, 2022

2012 journal article

Revealing Rotational Modes of Functionalized Gold Nanorods on Live Cell Membranes

Small, 9(5), 785–792.

author keywords: rotational dynamics; single particle tracking; correlation analysis; rotational modes; gold nanorods
MeSH headings : Cell Membrane; Gold / chemistry; Nanotechnology; Nanotubes / chemistry
TL;DR: The single particle orientation and rotational tracking (SPORT) technique is combined here with correlation analysis to identify the fundamental rotational modes: in-plane rotation and out-of-plane tilting, from the vast image data captured at a temporal resolution of 5 ms for single gold nanorod probes in live cell imaging experiments. (via Semantic Scholar)
Source: Crossref
Added: May 1, 2022

2012 report

Peptidomimetics Comprising N-Amino Cyclic Urea Residues and Uses Thereof

(Provisional Patent No. US 61/655,682).

By: W. Lubell, H. Ong, C. Proulx, R. Hopewell, K. Beauregard & Y. Garcia-Ramos

Source: NC State University Libraries
Added: March 6, 2022

2012 journal article

Electrical Resistance of Ag TS –S(CH 2 ) n −1 CH 3 //Ga 2 O 3 /EGaIn Tunneling Junctions

J. Phys. Chem. C, 116(20), 10848–10860.

By: L. Cademartiri*, M. Thuo*, C. Nijhuis*, W. Reus*, S. Tricard*, J. Barber*, R. Sodhi*, P. Brodersen* ...

Contributors: L. Cademartiri*, M. Thuo*, C. Nijhuis*, W. Reus*, S. Tricard*, J. Barber*, R. Sodhi*, P. Brodersen* ...

Source: ORCID
Added: January 25, 2022

2012 journal article

Directly Addressable Sub-3 nm Gold Nanogaps Fabricated by Nanoskiving Using Self-Assembled Monolayers as Templates

ACS Nano, 6(6), 5566–5573.

By: P. Pourhossein* & R. Chiechi*

Contributors: P. Pourhossein* & R. Chiechi*

author keywords: nanoskiving; nanogaps; molecular electronics; self-assembled monolayers; nanofabrication
MeSH headings : Electric Conductivity; Equipment Design; Equipment Failure Analysis; Gold / chemistry; Macromolecular Substances / chemistry; Materials Testing; Microelectrodes; Molecular Conformation; Molecular Imprinting / methods; Nanoparticles / chemistry; Nanoparticles / ultrastructure; Nanotechnology / instrumentation; Particle Size; Surface Properties
TL;DR: This paper describes the fabrication of electrically addressable, high-aspect-ratio (>10000:1) nanowires of gold with square cross sections of 100 nm on each side that are separated by gaps of 1.7-2.2 nm which were defined using self-assembled monolayers (SAMs) as templates. (via Semantic Scholar)
Source: ORCID
Added: January 25, 2022

2012 journal article

Polymer Electronics, Quo Vadis?

ACS Macro Lett., 1(10), 1180–1183.

Contributors: R. Chiechi* & J. Hummelen*

Source: ORCID
Added: January 25, 2022

2012 journal article

Thiol-containing polymeric embedding materials for nanoskiving

J. Mater. Chem. C, 1(1), 121.

By: R. Mays n, P. Pourhossein*, D. Savithri n, J. Genzer n, R. Chiechi* & M. Dickey n

Source: ORCID
Added: January 25, 2022

2012 journal article

Synthesis of hydrazine and azapeptide derivatives by alkylation of carbazates and semicarbazones

Canadian Journal of Chemistry, 90(11), 985–993.

By: Y. Garcia-Ramos*, C. Proulx* & W. Lubell*

author keywords: carbazate; tetraethylammonium hydroxide; semicarbazone; alkylation; fluorenone hydrazine
Sources: Crossref, ORCID
Added: December 18, 2021

2012 article

Enumeration of Isomers of Substituted Tetrapyrrole Macrocycles: From Classical Problems in Biology to Modern Combinatorial Libraries

Taniguchi, M., & Lindsey, J. S. (2012, July). Handbook of Porphyrin Science (Volume 23), pp. 1–80.

By: M. Taniguchi* & J. Lindsey

Source: ORCID
Added: October 17, 2021

2012 conference paper

Biosensors, biotechnologies and biomaterials

Presented at the 9th International Symposium on Persistent Toxic Substances, Miami, FL.

By: Y. Xiao

Event: 9th International Symposium on Persistent Toxic Substances at Miami, FL on October 23-27, 2012

Source: NC State University Libraries
Added: September 11, 2021

2012 journal article

“You have to know the past to (blog) the present:” Using an Educational Blog to Engage Students in U.S. History

Computers in the Schools, 29(1-2), 118–134.

By: M. Manfra n & J. Lee n

author keywords: educational weblogs (blogs); social studies; history education; authentic intellectual work; culturally relevant pedagogy; "doing history"
UN Sustainable Development Goal Categories
4. Quality Education (Web of Science; OpenAlex)
Sources: Crossref, ORCID
Added: August 16, 2021

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