Chemical and Biomolecular Engineering

Works Published in 2016

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Displaying works 21 - 40 of 253 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2016 journal article

In vivo continuous evolution of genes and pathways in yeast

Nature Communications.

By: N. Crook*, J. Abatemarco*, J. Sun*, J. Wagner*, A. Schmitz* & H. Alper*

MeSH headings : Directed Molecular Evolution / methods; Gene Expression Regulation, Fungal; Gene Library; Genes, Fungal / genetics; Kluyveromyces / genetics; Metabolic Networks and Pathways / genetics; Models, Genetic; Mutagenesis, Insertional; Mutation; Retroelements / genetics; Saccharomyces cerevisiae / genetics; Yeasts / classification; Yeasts / genetics; Yeasts / metabolism
TL;DR: The authors engineer the yeast retrotransposon Ty1 to enable the creation of large mutant libraries in vivo and use this system to generate improved variants of single enzymes and multigene pathways, which are found to yield higher-performing variants faster than error-prone PCR-derived libraries. (via Semantic Scholar)
Source: ORCID
Added: May 6, 2021

2016 journal article

Particles for Local Delivery of Proteins Using Intra-Articular Route

Advanced Healthcare Materials, 5(6), 653–658.

By: K. Khodabandehlou n, S. Tian*, J. Luft*, S. Khan n & J. DeSimone n

MeSH headings : Animals; Cattle; Freund's Adjuvant / chemistry; Freund's Adjuvant / immunology; Half-Life; Knee Joint / metabolism; Lactic Acid; Mice; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RAW 264.7 Cells; Rabbits; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / immunology; Serum Albumin, Bovine / metabolism
TL;DR: Slowly dissolving silylated microparticles are designed with specific size and shape that are capable of extending the retention time of a model protein (bovine serum albumin) in the murine knee joint. (via Semantic Scholar)
Source: Crossref
Added: March 26, 2021

2016 journal article

Data on biodistribution and radiation absorbed dose profile of a novel 64Cu-labeled high affinity cell-specific peptide for positron emission tomography imaging of tumor vasculature

Data in Brief, 7, 480–484.

By: J. Merrill*, K. Krajewski*, H. Yuan*, J. Frank*, D. Lalush n, C. Patterson*, A. Veleva n

author keywords: Molecular imaging; Tumor angiogenesis; Radiation absorbed dose; Diagnostic radiopharmaceuticals
TL;DR: Biodistribution measurements in mice are reported and the radiation absorbed doses to normal organs are calculated using a modified Medical Internal Radiation Dosimetry (MIRD) methodology that accounts for physical and geometric factors and cross-organ beta doses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Crossref
Added: November 21, 2020

2016 conference paper

A smartphone-based microplate reader for point-of-care ELISA quantification

2016 Conference on Lasers and Electro-Optics, CLEO 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-85010702301&partnerID=MN8TOARS

By: B. Berg, B. Cortazar, D. Tseng, H. Ozkan, S. Feng, Q. Wei, R. Chan, J. Burbano ...

Contributors: B. Berg, B. Cortazar, D. Tseng, H. Ozkan, S. Feng, Q. Wei, R. Chan, J. Burbano ...

Source: ORCID
Added: April 10, 2020

2016 journal article

Inside Cover: Oxidative Dehydrogenation of Ethane: A Chemical Looping Approach (Energy Technol. 10/2016)

Energy Technology, 4(10), 1126–1126.

By: L. Neal*, S. Yusuf*, J. Sofranko* & F. Li*

UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Crossref, ORCID, NC State University Libraries
Added: February 24, 2020

2016 journal article

Oxidative Dehydrogenation of Ethane: A Chemical Looping Approach

Energy Technology, 4(10), 1200–1208.

By: L. Neal*, S. Yusuf, J. Sofranko* & F. Li*

Contributors: L. Neal*, S. Yusuf, J. Sofranko* & F. Li*

author keywords: catalysis; chemical looping; ethane; oxidative dehydrogenation; redox reaction
Sources: Crossref, ORCID, NC State University Libraries
Added: February 24, 2020

2016 journal article

BMP signaling plays a biphasic role during trophoblast differentiation of human embryonic stem cells

Placenta, 45, 99–100.

By: P. Sarkar n, A. Mischler n & B. Rao n

Source: Crossref
Added: February 24, 2020

2016 journal article

Lithium-Ion Batteries: Excimer Ultraviolet-Irradiated Carbon Nanofibers as Advanced Anodes for Long Cycle Life Lithium-Ion Batteries (Small 38/2016)

Small, 12(38), 5231–5231.

By: Z. Shen*, Y. Hu*, Y. Chen*, R. Chen*, X. He*, L. Geng*, X. Zhang n, K. Wu*

Sources: Crossref, NC State University Libraries
Added: February 12, 2020

2016 journal article

Macromol. Rapid Commun. 22/2016

Macromolecular Rapid Communications, 37(22), 1785–1785.

Sources: Crossref, ORCID
Added: February 5, 2020

2016 journal article

Correction to “Self-Running Liquid Metal Drops that Delaminate Metal Films at Record Velocities”

Correction to “Self-Running Liquid Metal Drops that Delaminate Metal Films at Record Velocities.” ACS Applied Materials & Interfaces, 8(24), 15855–15855.

By: M. Mohammed, R. Sundaresan & M. Dickey*

TL;DR: D to a production error, the wrong Supporting Information file was associated with this article, and the new pdf file now corresponds to the description in the article. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 25, 2020

2016 journal article

Hierarchical Graphene-Containing Carbon Nanofibers for Lithium-Ion Battery Anodes

ACS Applied Materials & Interfaces, 8(2), 1327–1336.

By: M. Dufficy n, S. Khan n & P. Fedkiw n

author keywords: carbon nanofibers; electrospinning; graphene; lithium-ion battery; anode
TL;DR: Impedance spectroscopy of the composite anodes demonstrated that charge-transfer resistances decreased as GO content increased, implying that high GO loadings result in more electrochemically active material. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Crossref
Added: January 25, 2020

2016 journal article

Superior high-voltage aqueous carbon/ carbon supercapacitors operating with in situ electrodeposited polyvinyl alcohol borate gel polymer electrolytes

Journal of Materials Chemistry A, 4.

By: M. Jiang, J. Zhu, C. Chen, Y. Lu, E. Pampal, L. Luo, P. Zhu, X. Zhang

Source: ORCID
Added: August 15, 2019

2016 journal article

Sandwich structure of graphene-protected silicon/carbon nanofibers for lithium-ion battery anodes

Electrochimica Acta, 210.

By: Y. Chen, Y. Hu, Z. Shen, R. Chen, X. He, X. Zhang, Y. Zhang, K. Wu

Source: ORCID
Added: August 15, 2019

2016 journal article

Excimer ultraviolet-irradiated carbon nanofibers as advanced anodes for long cycle life lithium-ion batteries

Small (Weinheim An Der Bergstrasse, Germany), 12.

By: Z. Shen, Y. Hu, Y. Chen, R. Chen, X. He, L. Geng, X. Zhang, K. Wu

Source: ORCID
Added: August 15, 2019

2016 journal article

Controlled synthesis of carbon nanofibers anchored with ZnxCo3-xO4 nanocubes as binder-free anode materials for lithium ion batteries

ACS Applied Materials & Interfaces, 8.

By: R. Chen, Y. Hu, Z. Shen, Y. Chen, X. He, X. Zhang, Y. Zhang

Source: ORCID
Added: August 15, 2019

2016 journal article

Controllable synthesis of carbon-coated Sn-SnO2-carbon-nanofiber membrane as advanced binder-free anode for lithium-ion batteries

Electrochimica Acta, 188.

By: Z. Shen, Y. Hu, Y. Chen, R. Chen, X. He, X. Zhang, H. Shao, Y. Zhang

Source: ORCID
Added: August 15, 2019

2016 journal article

Novel materials

Proceedings of the National Academy of Sciences, 113(42), 11667–11669.

By: J. Rogers & J. DeSimone*

TL;DR: This Special Feature on Novel Materials presents a collection of perspectives articles, short reviews, and original research papers designed to capture some of the breadth and excitement in recent materials research. (via Semantic Scholar)
Source: Crossref
Added: June 30, 2019

2016 journal article

Subtumoral analysis of PRINT nanoparticle distribution reveals targeting variation based on cellular and particle properties

Nanomedicine: Nanotechnology, Biology and Medicine, 12(4), 1053–1062.

By: L. Roode*, H. Brighton*, T. Bo*, J. Perry*, M. Parrott*, F. Kersey*, J. Luft*, J. Bear*, J. DeSimone*, I. Davis*

author keywords: PRINT; Nanomedicine; Nanoparticle; Flow cytometry; Cancer
MeSH headings : Animals; Cell Line, Tumor; Disease Models, Animal; Flow Cytometry; Humans; Macrophages / drug effects; Macrophages / pathology; Melanoma / diagnostic imaging; Melanoma / pathology; Nanomedicine; Nanoparticles / administration & dosage; Nanoparticles / adverse effects; Particle Size; Tissue Distribution; Xenograft Model Antitumor Assays
TL;DR: The authors utilized PRINT-produced nanoparticles to investigate specific tumor uptake by multi-color flow cytometry and in vivo confocal tumor imaging, which allowed further in-depth correlation between nanoparticle properties and tumor cells and should improve future design. (via Semantic Scholar)
Source: Crossref
Added: June 30, 2019

2016 journal article

Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT® nanoparticle formulation against non-small-cell lung cancer brain metastases

Nanomedicine, 11(15), 1947–1955.

By: M. Sambade, A. Deal, A. Schorzman*, J. Luft, C. Bowerman*, K. Chu*, O. Karginova*, A. Swearingen ...

author keywords: acid-labile docetaxel prodrug; blood-brain barrier; Particle Replication in Non-wetting Templates (PRINT)(R) PLGA nanoparticle
MeSH headings : Animals; Blood-Brain Barrier / metabolism; Brain / drug effects; Brain / pathology; Brain Neoplasms / drug therapy; Brain Neoplasms / pathology; Brain Neoplasms / secondary; Carcinoma, Non-Small-Cell Lung / drug therapy; Carcinoma, Non-Small-Cell Lung / pathology; Carcinoma, Non-Small-Cell Lung / secondary; Cell Line, Tumor; Docetaxel; Heterografts; Humans; Lactic Acid / chemistry; Lung Neoplasms / drug therapy; Lung Neoplasms / pathology; Mice; Mice, Nude; Nanoparticles / chemistry; Neoplasm Transplantation; Particle Size; Polyglycolic Acid / chemistry; Polylactic Acid-Polyglycolic Acid Copolymer; Taxoids / administration & dosage; Taxoids / chemistry; Taxoids / pharmacokinetics
TL;DR: The decreased toxicity of the PRINT-C2-docetaxel improved treatment efficacy against non-small-cell lung cancer brain metastasis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: June 30, 2019

2016 journal article

Reduction Sensitive PEG Hydrogels for Codelivery of Antigen and Adjuvant To Induce Potent CTLs

Molecular Pharmaceutics, 13(10), 3381–3394.

By: C. Kapadia, S. Tian, J. Perry, J. Luft & J. DeSimone n

author keywords: nanoparticles; cancer vaccine; peptide vaccine; disulfide linkers; cytotoxic T cells (CTL)
MeSH headings : Adjuvants, Immunologic / administration & dosage; Animals; Antigens / administration & dosage; Antigens / immunology; Bone Marrow Cells / cytology; CD8-Positive T-Lymphocytes / metabolism; Cancer Vaccines / administration & dosage; Cancer Vaccines / metabolism; Cell Proliferation / physiology; Chromatography, High Pressure Liquid; Dendritic Cells / metabolism; Dynamic Light Scattering; Female; Hydrogels / chemistry; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Nanoparticles / chemistry; Oligodeoxyribonucleotides / chemistry; Oligodeoxyribonucleotides / immunology; Peptide Fragments / chemistry; Peptide Fragments / immunology; Polyethylene Glycols / chemistry; T-Lymphocytes, Cytotoxic / immunology; T-Lymphocytes, Cytotoxic / metabolism; Thermogravimetry
TL;DR: It is demonstrated that the reduction sensitive NP subunit vaccine elicits a potent CTL response and provides compelling evidence that this approach could be utilized to engineer particulate vaccines to deliver tumor or pathogen associated antigenic peptides to harness the immune system to fight against cancer and infectious diseases. (via Semantic Scholar)
Source: Crossref
Added: June 30, 2019

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