Works Published in 2002

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Displaying works 21 - 40 of 42 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2002 journal article

Insulin-like growth factor-1 inscribes a gene expression profile for angiogenic factors and cancer progression in breast epithelial cells

Neoplasia, 4(3), 204–217.

By: J. Oh, J. Kucab, P. Bushel, K. Martin, L. Bennett, J. Collins, R. Diaugustine, J. Barrett, C. Afshari, S. Dunn

MeSH headings : Blotting, Western; Cell Line; Cell Nucleus / metabolism; Cyclic AMP Response Element-Binding Protein / metabolism; Disease Progression; Endothelial Growth Factors / metabolism; Epithelium / pathology; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor I / biosynthesis; Insulin-Like Growth Factor I / genetics; Lymphokines / metabolism; Membrane Glycoproteins / metabolism; Models, Biological; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Phosphorylation; Promoter Regions, Genetic; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Urokinase-Type Plasminogen Activator / metabolism; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors
Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Efficacy of partially hydrolyzed corn syrup solids as a replacement for lactose in manufactured liquid diets for neonatal pigs

Journal of Animal Science, 80(1), 143–153.

By: W. Oliver n, S. Mathews n, O. Phillips n, E. Jones n, J. Odle n & R. Harrell n

MeSH headings : Animal Feed; Animals; Animals, Newborn / metabolism; Blood Urea Nitrogen; Diet / veterinary; Dietary Carbohydrates / administration & dosage; Digestion; Food, Formulated / standards; Hydrolysis; Jejunum / anatomy & histology; Lactase; Lactose / administration & dosage; Nutritive Value; Random Allocation; Swine / metabolism; Treatment Outcome; Weaning; Weight Gain; Zea mays; alpha-Glucosidases / metabolism; beta-Galactosidase / metabolism
TL;DR: The results suggest that partially hydrolyzed CSS can be used as a replacement for lactose in manufactured liquid diets for neonatal pigs. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2002 article

Cholesteryl ester transfer protein TaqI B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency - Veterans Affairs HDL Cholesterol Intervention Trial

Brousseau, M. E., JJ O'Connor, Ordovas, J. M., Collins, D., Otvos, J. D., Massov, T., … Schaefer, E. J. (2002, July). ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, Vol. 22, pp. 1148–1154.

By: M. Brousseau*, . JJ O'Connor, J. Ordovas*, D. Collins*, J. Otvos*, T. Massov*, . McNamara*, H. Rubins*, S. Robins*, E. Schaefer*

author keywords: cholesteryl ester transfer protein; coronary heart disease; high density lipoproteins; polymorphism; Veterans Affairs HDL-C Intervention Trial
MeSH headings : Alleles; Apolipoproteins / blood; Carrier Proteins / genetics; Carrier Proteins / metabolism; Cholesterol Ester Transfer Proteins; Cholesterol, HDL / blood; Cholesterol, HDL / deficiency; Cholesterol, HDL / genetics; Cholesterol, HDL / metabolism; Coronary Disease / etiology; Coronary Disease / genetics; Coronary Disease / prevention & control; Fasting / blood; Gemfibrozil / pharmacology; Gemfibrozil / therapeutic use; Genetic Markers / genetics; Genotype; Glycoproteins; Humans; Hypolipidemic Agents / pharmacology; Hypolipidemic Agents / therapeutic use; Lipid Metabolism; Lipid Metabolism, Inborn Errors / blood; Lipid Metabolism, Inborn Errors / complications; Lipid Metabolism, Inborn Errors / drug therapy; Lipid Metabolism, Inborn Errors / genetics; Lipids / blood; Lipoproteins, LDL / blood; Male; Middle Aged; Molecular Weight; Risk Factors; United States; United States Department of Veterans Affairs
TL;DR: The data demonstrate that in men with CHD and HDL deficiency, the CETP Taq I B2B2 genotype is significantly reduced and associated with higher levels of plasma HDL-C and lower CHD risk, and support the concept that increased LDL-C levels, resulting from reduced CETP activity, are associated with decreasedCHD risk. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

C-13-NMR study of hypoglycemia-induced glycolytic changes in embryonic mouse heart

TERATOLOGY, 66(5), 267–272.

MeSH headings : Animals; Carbon Isotopes; Culture Media; Glucose / metabolism; Glycolysis / physiology; Heart / embryology; Hypoglycemia / embryology; Hypoglycemia / metabolism; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Myocardium / metabolism; Organ Culture Techniques
TL;DR: NMR effectively measures glucose and its metabolite, lactate, in the same spectrum and thus determines metabolic flux in the isolated embryonic heart after exposure to hypoglycemia and normoglycemic media, suggesting that 13C-NMR spectroscopy can be used to study glucose metabolism in isolated embryonic hearts exposed to hyp glucosecemia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 article

Airways inflammation and COPD - Epithelial-neutrophil interactions

Pettersen, C. A., & Adler, K. B. (2002, May). CHEST, Vol. 121, pp. 142S–150S.

author keywords: airways inflammation; apoptosis; chemoattractants; chemokines; COPD; cytokines; epithelium; neutrophil
MeSH headings : Cell Adhesion Molecules / metabolism; Humans; Inflammation / physiopathology; Inflammation Mediators / metabolism; Neutrophil Activation / immunology; Pulmonary Disease, Chronic Obstructive / immunology; Respiratory Mucosa / immunology; Signal Transduction / immunology
TL;DR: Neutrophils are recognized as major cellular mediators of inflammation and contain specific and highly regulated mechanisms for controlling the expression of adhesion molecules that allow for their tethering and migration into inflammatory sites. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

A geminivirus replication protein interacts with a protein kinase and a motor protein that display different expression patterns during plant development and infection

PLANT CELL, 14(8), 1817–1832.

By: L. Kong n & L. Hanley-Bowdoin n

MeSH headings : Animals; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / virology; Arabidopsis Proteins / genetics; Arabidopsis Proteins / isolation & purification; Arabidopsis Proteins / metabolism; Biological Transport / physiology; DNA, Viral / genetics; Geminiviridae / genetics; Geminiviridae / growth & development; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Histones / metabolism; In Situ Hybridization; Kinesins / genetics; Kinesins / metabolism; Microtubule Proteins / metabolism; Mitosis / genetics; Mitosis / physiology; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Interaction Mapping; Protein Kinases / genetics; Protein Kinases / isolation & purification; Protein Kinases / metabolism; Protein Serine-Threonine Kinases / metabolism; Tobacco / virology; Two-Hybrid System Techniques; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR: The results establish that AL1 interacts with host proteins involved in plant cell division and development, including a Ser/Thr kinase, a kinesin, and histone H3 as AL1 partners. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

Conservation and synteny of SSR loci and QTLs for vegetative propagation in four Eucalyptus species

THEORETICAL AND APPLIED GENETICS, 105(2-3), 474–478.

By: C. Marques*, R. Brondani*, D. Grattapaglia* & R. Sederoff n

author keywords: SSR; mapping; QTLs; eucalyptus; synteny
TL;DR: Findings indicate high transferability of microsatellite markers between Eucalyptus species of the Symphyomyrtus subgenus and establish foundations for the use of synteny in the genetic analysis of this genus. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Azotobacter chroococcum does not contain sodA or its gene product Mn-superoxide dismutase

Canadian Journal of Microbiology, 48(2), 183–187.

By: J. Caldwell n & H. Hassan*

author keywords: FeSOD; Cu-ZnSOD; MnSOD; Azotobacter chroococcum; Azotobacter vinelandii
MeSH headings : Amino Acid Sequence; Azotobacter / enzymology; Azotobacter / genetics; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Superoxide Dismutase / analysis; Superoxide Dismutase / genetics
TL;DR: Results dispute the assertion that A. chroococcum contains Mn-superoxide dismutase and refute the assertion by Buchanan and Lees (Can. J. Microbiol. 26: 441-447, 1980). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

Accurate translation of the genetic code depends on tRNA modified nucleosides

JOURNAL OF BIOLOGICAL CHEMISTRY, 277(19), 16391–16395.

By: C. Yarian n, H. Townsend n, W. Czestkowski*, E. Sochacka*, A. Malkiewicz*, R. Guenther n, A. Miskiewicz*, P. Agris n

MeSH headings : Adenosine / analogs & derivatives; Adenosine / chemistry; Asparagine / chemistry; Base Pairing; Base Sequence; Codon; Genetic Code; Molecular Sequence Data; Nucleic Acid Conformation; Nucleosides / metabolism; Protein Biosynthesis; Protein Structure, Tertiary; RNA / metabolism; RNA, Messenger / metabolism; RNA, Ribosomal, 16S / metabolism; RNA, Transfer / metabolism; Ribosomes / metabolism; Thiouridine / analogs & derivatives; Thiouridine / chemistry; Uridine / analogs & derivatives; Uridine / chemistry
TL;DR: It is concluded that modified nucleosides evolved to modulate an anticodon domain structure necessary for many tRNA species to accurately translate the genetic code. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Immobilization and utilization of the recombinant fusion proteins trypsin-streptavidin and streptavidin-transglutaminase for modification of whey protein isolate functionality

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 50(13), 3723–3730.

author keywords: immobilization; trypsin; transglutaminase; whey protein; functionality
MeSH headings : Adsorption; Biotinylation; Chemical Phenomena; Chemistry, Physical; Cross-Linking Reagents; DNA, Recombinant; Dithiothreitol / pharmacology; Enzymes, Immobilized; Escherichia coli / genetics; Gels; Glass; Milk Proteins / chemistry; Milk Proteins / metabolism; Recombinant Fusion Proteins; Streptavidin / genetics; Temperature; Transglutaminases / genetics; Transglutaminases / metabolism; Trypsin / genetics; Trypsin / metabolism; Viscosity; Whey Proteins
TL;DR: By combining limited proteolysis with controlled cross-linking, it was possible to create derivatives of whey proteins with enhanced functional properties that allowed for recycling of the enzyme, eliminated the requirement for a downstream inactivation step, and permitted control over the extent of modification. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Identification and quantification of protecting groups remaining in commercial oligonucleotide products using monoclonal antibodies

ANALYTICAL BIOCHEMISTRY, 306(1), 135–143.

By: C. Fu n, S. Smith n, S. Simkins n & P. Agris n

author keywords: DNA; RNA; automated synthesis; protecting group detection; quality control
MeSH headings : Antibodies, Monoclonal / immunology; Antibody Specificity; Chromatography, High Pressure Liquid; DNA / chemistry; DNA / immunology; Enzyme-Linked Immunosorbent Assay; Immunoblotting / methods; Molecular Structure; Oligonucleotides / chemistry; Oligonucleotides / immunology; Quality Control; RNA / chemistry; RNA / immunology; Sensitivity and Specificity; Spectrum Analysis
TL;DR: Monoclonal antibodies selectively identify and quantify picomoles of remaining protecting groups on antisense therapeutics and oligonucleotide diagnostics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Binding of protein D/E to the surface of rat epididymal sperm before ejaculation and after deposition in the female reproductive tract

Journal of Andrology, 23(4), 512–521.

By: C. Tubbs, J. Hall, R. Scott, V. Clark, T. Hermon & C. Bazemore-Walker

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Archaeal ribosomal protein L7 is a functional homolog of the eukaryotic 15.5kD/Snu13p snoRNP core protein

Nucleic Acids Research, 30(4), 931–941.

By: J. Kuhn n, E. Tran n & E. Maxwell n

MeSH headings : Amino Acid Sequence; Archaeal Proteins / genetics; Archaeal Proteins / physiology; Binding Sites; Electrophoretic Mobility Shift Assay; Escherichia coli / genetics; Escherichia coli Proteins; Eukaryotic Cells / metabolism; Humans; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Denaturation; RNA, Small Nucleolar / chemistry; RNA, Small Nucleolar / metabolism; Recombinant Proteins / metabolism; Ribonucleoproteins, Small Nuclear / genetics; Ribosomal Proteins / genetics; Ribosomal Proteins / physiology; Saccharomyces cerevisiae Proteins / genetics; Sequence Homology, Amino Acid
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

TiC nanoisland formation on 6H-SiC(0001)(Si)

JOURNAL OF APPLIED PHYSICS, 91(9), 6081–6084.

UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Stoichiometries of protein - Protein/DNA binding and conformational changes for the transition-state regulator AbrB measured by pseudo cell-size exclusion chromatography-mass spectrometry

BIOCHEMISTRY, 41(25), 7859–7865.

By: J. Cavanagh n, R. Thompson n, B. Bobay n, L. Benson n & S. Naylor n

MeSH headings : Bacillus subtilis / chemistry; Bacterial Proteins / chemistry; Chromatography, Gel / instrumentation; Chromatography, Gel / methods; DNA / chemistry; DNA-Binding Proteins / chemistry; Electron Transport; Electron-Transferring Flavoproteins; Flavoproteins / chemistry; Geobacillus stearothermophilus / chemistry; Humans; Mass Spectrometry / instrumentation; Mass Spectrometry / methods; Protein Binding; Protein Conformation; Spectrometry, Mass, Electrospray Ionization / instrumentation; Spectrometry, Mass, Electrospray Ionization / methods; Transcription Factors / chemistry
TL;DR: On-line pseudo cell-size exclusion chromatography-mass spectrometry (PsC-SEC-MS) enables the efficient determination of gross conformational changes upon complexation and shows that when the complex binds to sinIR, the hydrodynamic volume of the complex is notably reduced compared to that of the apoprotein, indicating a protein conformational change. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Monitoring phosphorus mineralization from poultry manure using phosphatase assays and phosphorus-31 nuclear magnetic resonance spectroscopy

COMMUNICATIONS IN SOIL SCIENCE AND PLANT ANALYSIS, 33(7-8), 1205–1217.

By: D. Crouse n, H. Sierzputowska-Gracz n, R. Mikkelsen n & A. Wollum n

UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Studying the functional genomics of stress responses in loblolly pine with the Expresso microarray experiment management system

COMPARATIVE AND FUNCTIONAL GENOMICS, 3(3), 226–243.

By: L. Heath*, N. Ramakrishnan*, R. Sederoff n, R. Whetten n, B. Chevone*, C. Struble*, V. Jouenne*, D. Chen*, L. Zyl n, R. Grene*

author keywords: microarrays; data mining; experiment management systems; inductive logic programming; reactive oxygen species; drought stress; Pinus taeda; microarray design
TL;DR: The design of Expresso is described as well as results of analysis with Expresso that suggest the importance of molecular chaperones and membrane transport proteins in mechanisms conferring successful adaptation to long-term drought stress. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Effects of pravastatin treatment on lipoprotein subclass profiles and particle size in the PLAC-I trial

ATHEROSCLEROSIS, 160(1), 41–48.

By: J. Otvos n, I. Shalaurova n, D. Freedman* & R. Rosenson*

author keywords: lipoprotein subclasses; small LDL; HMG-CoA reductase inhibitors; CHD risk
MeSH headings : Aged; Arteriosclerosis / drug therapy; Dose-Response Relationship, Drug; Double-Blind Method; Endpoint Determination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use; Lipids / blood; Lipoproteins, HDL / blood; Lipoproteins, HDL / drug effects; Lipoproteins, LDL / blood; Lipoproteins, LDL / drug effects; Male; Middle Aged; Pravastatin / therapeutic use
TL;DR: High-risk CHD subjects with small LDL particles gain at least as much pharmacological benefit from pravastatin as those with large LDL, as evidenced by reductions in the numbers of total andSmall LDL particles, and increases in average LDL and HDL particle size. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 book

Principles of biochemistry

Upper Saddle River, NJ: Prentice Hall.

By: H. Horton

Source: NC State University Libraries
Added: August 6, 2018

2002 review

The nature of FSH induction by GnRH

[Review of ]. TRENDS IN ENDOCRINOLOGY AND METABOLISM, 13(6), 257–263.

By: W. Miller n, F. Shafiee-Kermani n, B. Strahl* & H. Huang*

MeSH headings : Animals; Enhancer Elements, Genetic; Follicle Stimulating Hormone / biosynthesis; Follicle Stimulating Hormone, beta Subunit / biosynthesis; Follicle Stimulating Hormone, beta Subunit / genetics; Gene Expression / drug effects; Gonadotropin-Releasing Hormone / pharmacology; Humans; Mice; Mice, Transgenic; Promoter Regions, Genetic; Transcription, Genetic / drug effects; Transforming Growth Factor beta / pharmacology
TL;DR: Past studies on GnRH induction of FSH are summarized, questions and approaches for the future are proposed, and the ability to express FSHB promoter-reporter constructs in transgenic mouse gonadotropes to test the physiological relevance of promoter elements identified by using L beta T2 cells is proposed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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