Works Published in 2011
Displaying works 21 - 40 of 40 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
Total skin electron therapy technique for the canine patient
Veterinary Radiology & Ultrasound, 52(3), 345–352.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Scattering functions of Platonic solids
JOURNAL OF APPLIED CRYSTALLOGRAPHY, 44, 545–557.
UN Sustainable Development Goal Categories
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Isolation and identification of antiplasmodial N-alkylamides from Spilanthes acmella flowers using centrifugal partition chromatography and ESI-IT-TOF-MS
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 879(21), 1886–1892.
author keywords: Centrifugal partition chromatography; N-alkylamides; Antiplasmodial activity
MeSH headings : Amides / chemistry; Amides / isolation & purification; Amides / pharmacology; Animals; Antimalarials / chemistry; Antimalarials / isolation & purification; Antimalarials / pharmacology; Asteraceae / chemistry; CHO Cells; Cell Survival / drug effects; Centrifugation; Chromatography, Liquid / methods; Cricetinae; Cricetulus; Flowers / chemistry; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum / drug effects; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR:
A systematic approach for investigating a suitable centrifugal partition chromatography (CPC) solvent system for N-alkylamides separation was reported, and CPC fractions demonstrated significantly higher antiplasmodial activity compared to corresponding purified N-alkinglamides, thus suggesting that interactions between these N-alklamides may potentiate antiplAsmodial bioactivity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Analysis of the ArcA regulon in anaerobically grown Salmonella enterica sv. Typhimurium
BMC MICROBIOLOGY, 11.
MeSH headings : Anaerobiosis; Animals; Female; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Metabolic Networks and Pathways / genetics; Mice; Mice, Inbred C57BL; Microarray Analysis; Regulon; Repressor Proteins / genetics; Repressor Proteins / metabolism; Salmonella typhimurium / genetics; Salmonella typhimurium / growth & development; Salmonella typhimurium / metabolism
TL;DR:
The results demonstrated that in S. Typhimurium, ArcA serves as a transcriptional regulator coordinating cellular metabolism, flagella biosynthesis, and motility, and a set of 120 genes whose regulation was shared with the anaerobic redox regulator, Fnr.
(via Semantic Scholar)
bmcmicrobiol.biomedcentral.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 review
Advances in qualitative and quantitative plant membrane proteomics
[Review of ]. PHYTOCHEMISTRY, 72(10), 1040–1060.
author keywords: Membrane proteomics; Liquid chromatography; Mass spectrometry; Quantitation; Quantification; Stable isotope-coded; Label-free
MeSH headings : Cell Membrane / chemistry; Cell Membrane / metabolism; Organelles / chemistry; Organelles / metabolism; Plant Proteins / analysis; Plant Proteins / metabolism; Protein Processing, Post-Translational; Proteomics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
YrdC exhibits properties expected of a subunit for a tRNA threonylcarbamoyl transferase
RNA, 17(9), 1678–1687.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Redox-Promoting Protein Motions in Rubredoxin
JOURNAL OF PHYSICAL CHEMISTRY B, 115(28), 8925–8936.
MeSH headings : Computer Simulation; Models, Molecular; Molecular Dynamics Simulation; Oxidation-Reduction; Rubredoxins / chemistry; Static Electricity
TL;DR:
This study reports on the characterization of temperature-activated collective and individual atomic motions of oxidized rubredoxin, a small 53 residue protein from thermophilic Pyrococcus furiosus (RdPf).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
Molecular and Serological Diagnosis of Bartonella Infection in 61 Dogs from the United States
JOURNAL OF VETERINARY INTERNAL MEDICINE, 25(4), 805–810.
author keywords: Bacteria; BAPGM; Bartonella; Blood culture
MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / blood; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Culture Media; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Logistic Models; Multivariate Analysis; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Retrospective Studies
TL;DR:
Dogs were most often infected with B. henselae or B. berkhoffii based on PCR and enrichment culture, coinfection was documented, and various Bartonella species were identified.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Functional recognition of the modified human tRNA(UUU)(Lys3) anticodon domain by HIV's nucleocapsid protein and a peptide mimic
Journal of Molecular Biology, 410(4), 698–715.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Flustramine inspired synthesis and biological evaluation of pyrroloindoline triazole amides as novel inhibitors of bacterial biofilms
ORGANIC & BIOMOLECULAR CHEMISTRY, 9(15), 5476–5481.
MeSH headings : Amides / chemical synthesis; Amides / chemistry; Amides / pharmacology; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Biofilms / drug effects; Indole Alkaloids / chemistry; Indoles / chemical synthesis; Indoles / chemistry; Indoles / pharmacology; Inhibitory Concentration 50; Molecular Structure; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Quantitative Structure-Activity Relationship; Small Molecule Libraries / chemical synthesis; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology
TL;DR:
Screening for the ability to modulate biofilm formation against strains of Gram-positive and Gram-negative bacteria identified several compounds with low micromolar, non-toxic IC(50) values.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 508(1), 31–38.
author keywords: Apoptosis; Caspase activation; Enzyme activity; Protein folding and assembly
MeSH headings : Caspase 3 / chemistry; Caspase 3 / genetics; Caspase 3 / metabolism; Catalytic Domain; Crystallography, X-Ray; Enzyme Stability; Hydrogen Bonding; Models, Molecular; Mutation; Protein Folding; Static Electricity; Structure-Activity Relationship; Thermodynamics
TL;DR:
Results suggest E246 and K242 are important in procaspase-3 for their interaction with neighboring residues, not with one another, and formation of the K242-E246 salt bridge in caspases3 is needed for an accurate, stable conformation of loop L4 and proper active site formation in the mature enzyme.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
BCR-ABL translocation in a dog with chronic monocytic leukemia
VETERINARY CLINICAL PATHOLOGY, 40(1), 40–47.
author keywords: FISH; flow cytometry; monocytosis; myeloproliferative disorder
MeSH headings : Animals; Bone Marrow Cells / pathology; Dog Diseases / diagnosis; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Flow Cytometry / veterinary; Leukemia, Myeloid / diagnosis; Leukemia, Myeloid / genetics; Leukemia, Myeloid / pathology; Leukemia, Myeloid / veterinary; Translocation, Genetic / genetics
TL;DR:
Clinical and laboratory findings and the protracted course supported a diagnosis of chronic monocytic leukemia (CMoL), the first case of CMoL with a BCR-ABL chromosomal abnormalitiy described in dogs, and may have clinical implications for treatment of dogs with chronic leukemias associated with particular genetic mutations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways
PLACENTA, 32(2), 175–182.
author keywords: Placenta; Preeclampsia; Maternal hypertension; Sialic acid acetylesterase
MeSH headings : Acetylesterase / biosynthesis; Antigens, CD / biosynthesis; Endoglin; Female; Genome-Wide Association Study; Humans; Infant, Newborn; Inhibins / biosynthesis; Male; Pre-Eclampsia / etiology; Pre-Eclampsia / metabolism; Pregnancy; Protein Array Analysis; Receptors, Cell Surface / biosynthesis; Trophoblasts / physiology; Up-Regulation; Vascular Endothelial Growth Factor Receptor-1 / biosynthesis
TL;DR:
Evidence is found of preeclampsia-associated placental upregulation of sialic acid acetylesterase (SIAE), a gene functionally associated with autoimmune diseases, and changes in immune-associated signaling pathways, offering a potential upstream explanation for the shallow trophoblast invasion and inadequate uterine remodeling typically observed in pathogenesis of preeClampsia.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Observing selected domains in multi-domain proteins via sortase-mediated ligation and NMR spectroscopy
JOURNAL OF BIOMOLECULAR NMR, 49(1), 3–7.
author keywords: Segmental labeling; Sortase A; Protein ligation; MecA; Enzyme-mediated ligation; NMR
MeSH headings : Amino Acid Sequence; Aminoacyltransferases / metabolism; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Cysteine Endopeptidases / metabolism; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nitrogen Isotopes / chemistry; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Proteins / chemistry; Proteins / metabolism; Recombinant Fusion Proteins / chemistry; Recombinant Fusion Proteins / metabolism; Staphylococcus aureus / enzymology
TL;DR:
It is shown that the S. aureus transpeptidase sortase A can be used to catalyze the ligation of two separately expressed domains of the same protein, MecA (B. subtilis), and the resultant HSQC spectrum obtained from this domain-labeled conjugate demonstrates successful application ofsortase A for segmental labeling of multi-domain proteins for solution NMR study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Role of the Vacuolar-ATPase in Sindbis Virus Infection
JOURNAL OF VIROLOGY, 85(3), 1257–1266.
MeSH headings : Animals; Cells, Cultured; Cricetinae; Enzyme Inhibitors / metabolism; Host-Pathogen Interactions; Macrolides / metabolism; Sindbis Virus / physiology; Vacuolar Proton-Translocating ATPases / metabolism; Virus Internalization; Virus Replication
TL;DR:
The results suggest that in BHK cells in the presence of bafilomycin A1, virus RNA enters the cell and is translated, but replication and proper folding of the product proteins requires the function of the V-ATPase.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Fur Negatively Regulates hns and Is Required for the Expression of HilA and Virulence in Salmonella enterica Serovar Typhimurium
JOURNAL OF BACTERIOLOGY, 193(2), 497–505.
MeSH headings : Animals; Bacterial Proteins / biosynthesis; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Chromatin Immunoprecipitation; DNA, Bacterial / metabolism; DNA-Binding Proteins / biosynthesis; DNA-Binding Proteins / metabolism; Disease Models, Animal; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Genes, Bacterial; Genomic Islands; Mice; Mice, Inbred C3H; Operon; Protein Binding; Repressor Proteins / genetics; Repressor Proteins / metabolism; Salmonella Infections, Animal / microbiology; Salmonella typhimurium / pathogenicity; Salmonella typhimurium / physiology; Survival Analysis; Trans-Activators / biosynthesis; Transcription Factors / biosynthesis; Virulence; Virulence Factors / biosynthesis
TL;DR:
Fur is required for virulence in Salmonella enterica serovar Typhimurium and that Fur is necessary for the activation of hilA, as well as of other HilA-dependent genes, invF and sipC, and chromatin immunoprecipitation was used to show that Fur bound to the upstream region of hns in a metal-dependent fashion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Functional Analysis of a Novel Motif Conserved across Geminivirus Rep Proteins
JOURNAL OF VIROLOGY, 85(3), 1182–1192.
MeSH headings : Amino Acid Motifs; Amino Acid Sequence; Conserved Sequence; DNA Helicases / genetics; DNA Helicases / metabolism; DNA, Viral / metabolism; Geminiviridae / enzymology; Geminiviridae / genetics; Geminiviridae / physiology; Molecular Sequence Data; Mutation, Missense; Plant Diseases / virology; Protein Binding; Sequence Alignment; Tobacco / virology; Trans-Activators / genetics; Trans-Activators / metabolism; Viral Proteins / genetics; Viral Proteins / metabolism; Virulence; Virus Replication
TL;DR:
It is established that the GRS is a conserved, essential motif characteristic of an ancient lineage of rolling-circle initiators and support the idea that geminiviruses may have evolved from plasmids associated with phytoplasma or algae.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
JOURNAL OF BIOLOGICAL CHEMISTRY, 286(5), 3323–3331.
MeSH headings : Allosteric Regulation; Allosteric Site; Animals; Guanosine Triphosphate / metabolism; Kinetics; Mice; Mutation, Missense; NIH 3T3 Cells; Protein Conformation; Protein Stability; Signal Transduction; raf Kinases / metabolism; ras Proteins / genetics; ras Proteins / metabolism
TL;DR:
The allosteric switch is linked to the control of signaling in the Ras/Raf/MEK/ERK pathway, supporting a GTPase-activating protein-independent model for duration of the Ras-Raf complex.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
The Spatial-Functional Coupling of Box C/D and C '/D ' RNPs Is an Evolutionarily Conserved Feature of the Eukaryotic Box C/D snoRNP Nucleotide Modification Complex
MOLECULAR AND CELLULAR BIOLOGY, 31(2), 365–374.
MeSH headings : Archaeal Proteins / genetics; Archaeal Proteins / metabolism; Base Sequence; Eukaryota / genetics; Evolution, Molecular; Fungal Proteins / genetics; Fungal Proteins / metabolism; Humans; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Nucleotides / genetics; Nucleotides / metabolism; RNA, Archaeal / genetics; RNA, Archaeal / metabolism; RNA, Guide, Kinetoplastida / genetics; RNA, Guide, Kinetoplastida / metabolism; Ribonucleoproteins / chemistry; Ribonucleoproteins / genetics; Ribonucleoproteins / metabolism; Ribonucleoproteins, Small Nucleolar / chemistry; Ribonucleoproteins, Small Nucleolar / genetics; Ribonucleoproteins, Small Nucleolar / metabolism
TL;DR:
The spatial-functional coupling of box C/D and C′/D′ RNPs is an evolutionarily conserved feature of both archaeal and eukaryotic box C /D RNP complexes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Investigation of solubilization and digestion methods for microsomal membrane proteome analysis using data-independent LC-MSE
PROTEOMICS, 11(5), 898–911.
author keywords: Bottom-up proteomics; Data-independent analysis; Denaturants; LC-MSE; Membrane proteomics; Technology
MeSH headings : Chromatography, Liquid; Guanidine / chemistry; Solanum lycopersicum / chemistry; Membrane Proteins / analysis; Membrane Proteins / chemistry; Membrane Proteins / metabolism; Methanol / chemistry; Microsomes / chemistry; Microsomes / enzymology; Peptide Fragments / analysis; Peptide Fragments / chemistry; Peptide Fragments / metabolism; Plant Roots / chemistry; Plant Roots / cytology; Proteome / analysis; Proteome / chemistry; Proteome / metabolism; Proteomics / methods; Solubility; Surface-Active Agents / chemistry; Tandem Mass Spectrometry; Trypsin / metabolism
TL;DR:
The results reveal the complementary nature of each denaturant method, which can be used in an integrated approach to provide a more effective bottom‐up analysis of membrane proteomes than can be achieved using only a singleDenaturant.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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