Works Published in 2013
Displaying works 21 - 40 of 48 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2013 journal article
New insight into the structure of RNA in red clover necrotic mosaic virus and the role of divalent cations revealed by small-angle neutron scattering
ARCHIVES OF VIROLOGY, 158(8), 1661–1669.
TL;DR:
Small-angle neutron scattering with contrast variation experiments were performed to better understand the organization of the RNA and conformational changes resulting from the removal of divalent cations in red clover necrotic mosaic virus and provide new insight into changes in the RNA packing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
High-level gene expression in differentiating xylem of tobacco driven by a 2.0 kb Poplar COMT2 promoter and a 4 x 35S enhancer
PLANT BIOTECHNOLOGY, 30(2), 191–198.
author keywords: PtrCOMT2 promoter; xylem-specific; 4 x 35S enhancer; woody plants; genetic engineering
TL;DR:
While expression of some of the enhancer-plus-promoter constructs increased expression, there was a loss of specificity in the PtrCOMT2 promoter.
(via Semantic Scholar)
www.jstage.jst.go.jp (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Environmental drivers of demographics, habitat use, and behavior during a post-Pleistocene radiation of Bahamas mosquitofish (Gambusia hubbsi)
EVOLUTIONARY ECOLOGY, 27(5), 971–991.
author keywords: Adaptive radiation; Blue holes; Competition; Ecological divergence; Habitat shift; Predation
TL;DR:
Variation in predation risk appears to represent the primary driver of ecological differentiation in this system, but other previously underappreciated factors (interspecific competition, resource availability) are notable contributors as well.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Role of AMP-Activated Protein Kinase in Ferritin H Gene Expression by Resveratrol in Human T Cells
BIOCHEMISTRY, 52(30), 5075–5083.
MeSH headings : AMP-Activated Protein Kinases / antagonists & inhibitors; AMP-Activated Protein Kinases / chemistry; AMP-Activated Protein Kinases / genetics; AMP-Activated Protein Kinases / metabolism; Antioxidants / chemistry; Antioxidants / pharmacology; Apoferritins / genetics; Apoferritins / metabolism; Enzyme Activation / drug effects; Gene Expression Regulation / drug effects; Glycogen Synthase Kinase 3 / antagonists & inhibitors; Glycogen Synthase Kinase 3 / genetics; Glycogen Synthase Kinase 3 / metabolism; Glycogen Synthase Kinase 3 beta; Humans; Jurkat Cells; K562 Cells; Leukocytes, Mononuclear / drug effects; Leukocytes, Mononuclear / metabolism; NF-E2-Related Factor 2 / metabolism; Oxidative Stress / drug effects; Phosphorylation / drug effects; Protein Processing, Post-Translational / drug effects; RNA Interference; Response Elements / drug effects; Resveratrol; Serine / metabolism; Stilbenes / antagonists & inhibitors; Stilbenes / pharmacology; T-Lymphocytes / drug effects; T-Lymphocytes / metabolism
TL;DR:
It is found that AMP-activated protein kinase (AMPK) plays a key role in the activation of nuclear factor E2-related factor (Nrf2) and subsequent ARE-dependent ferritin H gene transcription by resveratrol.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Gonadotrope-Specific Expression and Regulation of Ovine Follicle Stimulating Hormone Beta: Transgenic and Adenoviral Approaches Using Primary Murine Gonadotropes
PLOS ONE, 8(7).
MeSH headings : Adenoviridae; Analysis of Variance; Animals; DNA Primers / genetics; Enhancer Elements, Genetic / genetics; Follicle Stimulating Hormone, beta Subunit / genetics; Follicle Stimulating Hormone, beta Subunit / metabolism; Gene Expression Regulation / physiology; Gonadotrophs / metabolism; Luciferases; Mice; Mice, Transgenic; Promoter Regions, Genetic / genetics; Real-Time Polymerase Chain Reaction; Sheep / genetics; Sheep / physiology
TL;DR:
It is concluded that adenoviral-based studies in primary gonadotropes can adequately recognize regulatory elements on the ovine FSHB promoter associated with gonadotrope-specific regulation/expression, but that more physiologically based techniques will be needed to identify sequences between −1866/−750 bp of the Ovine F SHB promoter that are also required for tissue/cell specific expression in vivo.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 review
Geminiviruses: masters at redirecting and reprogramming plant processes
[Review of ]. NATURE REVIEWS MICROBIOLOGY, 11(11), 777–788.
MeSH headings : Geminiviridae / physiology; Gene Expression Regulation, Viral / physiology; Genome, Viral; Host-Pathogen Interactions; Plant Diseases / virology; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR:
This Review describes the current knowledge of how geminiviruses interact with their plant hosts and the functional consequences of these interactions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science; OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Binding Polymorphism in the DNA Bound State of the Pdx1 Homeodomain
PLOS COMPUTATIONAL BIOLOGY, 9(8).
TL;DR:
Both the crystal and aqueous simulations support the existence of different stable binding conformers identified in the original crystallographic data with different degrees of specificity and propose that protein-protein and protein-DNA interactions favor a subset of the possible conformations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Autophosphorylation of gatekeeper tyrosine by symbiosis receptor kinase
FEBS LETTERS, 587(18), 2972–2979.
author keywords: Autophosphorylation; Gatekeeper residue; Receptor-like kinase; Symbiosis receptor kinase; Tyrosine kinase-like
MeSH headings : Amino Acid Motifs; Arachis / genetics; Arachis / metabolism; Catalytic Domain; Cell Line; Gene Expression Regulation, Plant; Mutation; Phosphorylation; Plant Proteins / genetics; Plant Proteins / metabolism; Protein Binding; Receptor Protein-Tyrosine Kinases / genetics; Receptor Protein-Tyrosine Kinases / metabolism; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Signal Transduction; Tyrosine / genetics; Tyrosine / metabolism
TL;DR:
It is hypothesize gatekeeper phosphorylation to be associated with synthesis/maturation of AhSYMRK and this phenomenon may be prevalent among RLKs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Sensitivity, positive predictive value, and interobserver variability of computed tomography in the diagnosis of bullae associated with spontaneous pneumothorax in dogs: 19 cases (2003-2012)
Journal of the American Veterinary Medical Association, 243(2), 244–251.
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
Regulation of phenylalanine ammonia-lyase (PAL) gene family in wood forming tissue of Populus trichocarpa
Planta, 238(3), 487–497.
MeSH headings : Gene Expression Regulation, Plant / physiology; Mass Spectrometry; Phenylalanine Ammonia-Lyase / metabolism; Populus / enzymology; Populus / metabolism
TL;DR:
A greater functional significance of subgroup A PtrPALs for stem wood formation is indicated, and the role of gene post-transcriptional regulation is highlighted.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
Ptr-miR397a is a negative regulator of laccase genes affecting lignin content in Populus trichocarpa
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(26), 10848–10853.
MeSH headings : Base Sequence; Down-Regulation / genetics; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gene Regulatory Networks; Genes, Plant; Laccase / antagonists & inhibitors; Laccase / genetics; Lignin / antagonists & inhibitors; Lignin / chemistry; Lignin / metabolism; MicroRNAs / genetics; MicroRNAs / metabolism; Phylogeny; Plant Proteins / genetics; Populus / enzymology; Populus / genetics; RNA, Plant / genetics; RNA, Plant / metabolism
TL;DR:
A hierarchical genetic regulatory network (GRN) built by a bottom-up graphic Gaussian model algorithm provides additional support for a role of ptr-miR397a as a negative regulator of laccases for lignin biosynthesis in wood formation.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Identification and Functional Analysis of Tomato BRI1 and BAK1 Receptor Kinase Phosphorylation Sites
PLANT PHYSIOLOGY, 163(1), 30–42.
MeSH headings : Binding Sites; Kinetics; Solanum lycopersicum / enzymology; Phosphorylation; Plant Proteins / chemistry; Plant Proteins / metabolism; Protein Serine-Threonine Kinases / chemistry; Protein Serine-Threonine Kinases / metabolism; Signal Transduction
TL;DR:
Liquid chromatography-tandem mass spectrometry was used to identify multiple in vitro phosphorylation sites of the tomato BRI1 and BAK1 cytoplasmic domains and found that tomato TRIP1 is a substrate of both tomato Bri1 andBAK1 kinases in vitro.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 article
What Is Your Diagnosis?
Boswell, S. G., Fogle, C. A., Linder, K., & Copple, C. N. (2013, February 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 242, pp. 311–313.
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Horse Diseases / diagnosis; Horse Diseases / pathology; Horse Diseases / therapy; Horses; Lymphedema / diagnosis; Lymphedema / pathology; Lymphedema / therapy; Lymphedema / veterinary; Male
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Structural and Kinetic Study of an Internal Substrate Binding Site in Dehaloperoxidase-Hemoglobin A from Amphitrite ornata
BIOCHEMISTRY, 52(14), 2427–2439.
MeSH headings : 2-Propanol / chemistry; Animals; Crystallography, X-Ray; Dimethyl Sulfoxide / chemistry; Hemoglobins / chemistry; Hemoglobins / metabolism; Kinetics; Methanol / chemistry; Models, Molecular; Peroxidases / chemistry; Peroxidases / metabolism; Phenols / chemistry; Polychaeta / chemistry; Polychaeta / enzymology; Polychaeta / metabolism; Protein Conformation
TL;DR:
The X-ray crystal structure is consistent with the presence of an internal active site above the heme α-edge, in which the substrate would be oxidized in two consecutive steps inside the enzyme, followed by attack by H2O via a water channel in the protein.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Chikungunya Virus Host Range E2 Transmembrane Deletion Mutants Induce Protective Immunity against Challenge in C57BL/6J Mice
JOURNAL OF VIROLOGY, 87(12), 6748–6757.
MeSH headings : Alphavirus Infections / immunology; Alphavirus Infections / prevention & control; Alphavirus Infections / virology; Animals; Antibodies, Neutralizing / blood; Antibodies, Viral / blood; Cell Line; Chikungunya Fever; Chikungunya virus / genetics; Chikungunya virus / immunology; Chikungunya virus / pathogenicity; Chikungunya virus / physiology; Host Specificity; Humans; Mice; Mice, Inbred C57BL; Mutation; Sequence Deletion; Vaccines, Attenuated / genetics; Vaccines, Attenuated / immunology; Viral Vaccines / genetics; Viral Vaccines / immunology; Virus Replication
TL;DR:
This study identified a ChikV HR mutant that grows to high levels in insect cells but was restricted in the ability to assemble virus in mammalian cells in vitro.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Monolignol Pathway 4-Coumaric Acid: Coenzyme A Ligases in Populus trichocarpa: Novel Specificity, Metabolic Regulation, and Simulation of Coenzyme A Ligation Fluxes
PLANT PHYSIOLOGY, 161(3), 1501–1516.
MeSH headings : Allosteric Regulation / drug effects; Binding Sites; Biosynthetic Pathways / drug effects; Blotting, Western; Caffeic Acids / pharmacology; Coenzyme A / metabolism; Coenzyme A Ligases / antagonists & inhibitors; Coenzyme A Ligases / metabolism; Computer Simulation; Coumaric Acids / chemistry; Coumaric Acids / metabolism; Coumaric Acids / pharmacology; Kinetics; Lignin / biosynthesis; Lignin / chemistry; Phenylpropionates / metabolism; Phosphoproteins / metabolism; Phosphorylation / drug effects; Plant Extracts; Populus / drug effects; Populus / enzymology; Propionates; Proteomics; Recombinant Fusion Proteins / metabolism; Sequence Homology, Amino Acid; Substrate Specificity / drug effects; Xylem / drug effects; Xylem / metabolism
TL;DR:
Evidence is presented of two monolignol 4CLs, Ptr4CL3 and P tr4CL5, in Populus trichocarpa that act to mitigate the inhibition by caffeic acid to maintain a proper ligation flux and coenzyme A flux with novel specificity.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Growth Requirements and Chromosomal Instability of Induced Pluripotent Stem Cells Generated from Adult Canine Fibroblasts
STEM CELLS AND DEVELOPMENT, 22(6), 951–963.
MeSH headings : Alkaline Phosphatase / metabolism; Animals; Antigens, Differentiation / genetics; Antigens, Differentiation / metabolism; Cell Differentiation; Cell Shape; Cells, Cultured; Chromosomal Instability; Coculture Techniques; Comparative Genomic Hybridization; Dogs; Fibroblasts / physiology; Gene Expression; In Situ Hybridization, Fluorescence; Induced Pluripotent Stem Cells / enzymology; Induced Pluripotent Stem Cells / pathology; Induced Pluripotent Stem Cells / transplantation; Kruppel-Like Factor 4; Mice; Mice, SCID; Recombinant Proteins / biosynthesis; Recombinant Proteins / genetics; Teratoma / genetics; Teratoma / pathology; Transcription Factors / biosynthesis; Transcription Factors / genetics
TL;DR:
The isolated ciPSCs have similar characteristics to ESCs from other species, but the exact cellular mechanisms behind their unique co-dependency on both FGF2 and LIF are still unknown.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Efficient Quantification of the Health-Relevant Anthocyanin and Phenolic Acid Profiles in Commercial Cultivars and Breeding Selections of Blueberries (Vaccinium spp.)
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 61(20), 4806–4815.
author keywords: anthocyanins; chlorogenic acid; blueberry; HPLC-DAD-MS; Vaccinium spp.; freeze-drying; health benefits
MeSH headings : Anthocyanins / analysis; Blueberry Plants / chemistry; Breeding; Chromatography, High Pressure Liquid / methods; Food, Preserved / analysis; Frozen Foods / analysis; Fruit / chemistry; Genotype; Glucosides / analysis; Health Promotion; Humans; Hydroxybenzoates / analysis; Plant Extracts / chemistry; Species Specificity; Tandem Mass Spectrometry / methods
TL;DR:
An improved protocol was developed for the accurate, efficient, and rapid comparative screening for large blueberry sample sets and different genotypes frequently had comparable overall levels of total anthocyanins and phenolic acids, but differed dramatically in individual profiles of compounds.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Characterizing polymer macrostructures by identifying and locating microstructures along their chains with the kerr effect
JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, 51(9), 735–741.
author keywords: microstructure; solution properties; structure-property relations; thin films
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Alphavirus Genome Delivery Occurs Directly at the Plasma Membrane in a Time- and Temperature-Dependent Process
JOURNAL OF VIROLOGY, 87(8), 4352–4359.
MeSH headings : Animals; Cell Membrane / virology; Cells, Cultured; Cricetinae; Microscopy, Immunoelectron; RNA, Viral / metabolism; Sindbis Virus / physiology; Staining and Labeling / methods; Temperature; Time Factors; Virus Internalization
TL;DR:
It is concluded that entry of alphaviruses is by direct penetration of cell plasma membranes through a pore structure formed by virus and, possibly, host proteins.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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