Molecular and Structural Biochemistry

College of Agriculture and Life Sciences

Works Published in 2012

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Displaying works 1 - 20 of 41 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2012 report

Attenuated FNR Deficient Enterobacteria

(US Patent No. 8,101,168).

By: H. Hassan, R. Fink & M. Evans

Source: NC State University Libraries
Added: March 12, 2022

2012 journal article

CIRCADIAN CLOCK-ASSOCIATED 1 regulates ROS homeostasis and oxidative stress responses.

Proceedings of the National Academy of Sciences of the United States of America.

author keywords: redox homeostasis; transcriptional coordination
MeSH headings : Arabidopsis / physiology; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Arabidopsis Proteins / physiology; Chromatin Immunoprecipitation; Computational Biology; Gene Expression Regulation, Plant / genetics; Gene Expression Regulation, Plant / physiology; Homeostasis / genetics; Homeostasis / physiology; Luminescent Measurements; Mutation / genetics; Oxidative Stress / physiology; Polymerase Chain Reaction; Reactive Oxygen Species / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism; Transcription Factors / physiology
Source: ORCID
Added: January 25, 2021

2012 journal article

Circadian surprise--it's not all about transcription.

Science (New York, N.Y.).

MeSH headings : Animals; CLOCK Proteins / genetics; Chromatin / metabolism; Circadian Clocks / genetics; Circadian Rhythm / genetics; Cryptochromes / genetics; Epigenesis, Genetic; Gene Expression Regulation; Liver / physiology; Male; RNA-Binding Proteins / metabolism; Transcription, Genetic; Transcriptional Activation
Source: ORCID
Added: January 25, 2021

2012 journal article

UDP-glucose Dehydrogenase Polymorphisms from Patients with Congenital Heart Valve Defects Disrupt Enzyme Stability and Quaternary Assembly

Journal of Biological Chemistry, 287(39), 32708–32716.

By: A. Hyde*, E. Farmer*, K. Easley*, K. van Lammeren*, V. Christoffels*, J. Barycki*, J. Bakkers*, M. Simpson*

MeSH headings : Amino Acid Substitution; Animals; Animals, Genetically Modified / embryology; Animals, Genetically Modified / genetics; Enzyme Stability / genetics; Escherichia coli; Heart Defects, Congenital / embryology; Heart Defects, Congenital / enzymology; Heart Defects, Congenital / genetics; Heart Valve Diseases / embryology; Heart Valve Diseases / enzymology; Heart Valve Diseases / genetics; Heart Valves / embryology; Heart Valves / enzymology; Muscle Proteins / genetics; Muscle Proteins / metabolism; Mutation, Missense; Polymorphism, Genetic; Protein Structure, Quaternary; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Uridine Diphosphate Glucose Dehydrogenase; Zebrafish / embryology; Zebrafish / genetics; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
Source: Crossref
Added: August 28, 2020

2012 journal article

Arabidopsis circadian clock protein, TOC1, is a DNA-binding transcription factor.

Proceedings of the National Academy of Sciences of the United States of America.

author keywords: transcriptional regulation; transcriptional potential; gene networks; circadian outputs; diurnal
MeSH headings : Amino Acid Sequence; Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / chemistry; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Base Sequence; Circadian Clocks / genetics; DNA, Plant / metabolism; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Gene Expression Regulation, Plant; Genes, Plant / genetics; Molecular Sequence Data; Promoter Regions, Genetic / genetics; Protein Binding; Protein Structure, Tertiary; Repressor Proteins / metabolism; Transcription Factors / chemistry; Transcription Factors / genetics; Transcription Factors / metabolism; Transcription, Genetic
Source: ORCID
Added: June 25, 2019

2012 journal article

A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities

BIOCHEMISTRY, 51(48), 9706–9717.

By: X. Lu n, G. Guanga, C. Wan & R. Rose n

MeSH headings : Amino Acid Sequence; Base Sequence; Crystallography, X-Ray; DNA / metabolism; DNA Primers; Electrophoretic Mobility Shift Assay; Leucine Zippers; Maf Transcription Factors, Large / chemistry; Maf Transcription Factors, Large / metabolism; Molecular Sequence Data; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Testing of Novel Dengue Virus 2 Vaccines in African Green Monkeys: Safety, Immunogenicity, and Efficacy

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 87(4), 743–753.

By: K. Smith, K. Nanda, V. McCarl, C. Spears, A. Piper*, M. Ribeiro, M. Quiles, C. Briggs ...

MeSH headings : Animals; Antibodies, Neutralizing / blood; Antibodies, Viral / blood; Cells, Cultured; Chlorocebus aethiops; Dengue / immunology; Dengue / prevention & control; Dengue / virology; Dengue Vaccines / adverse effects; Dengue Vaccines / genetics; Dengue Vaccines / immunology; Dengue Vaccines / therapeutic use; Dengue Virus / genetics; Dengue Virus / immunology; Immunization; Neutralization Tests; Viral Envelope Proteins / genetics; Viral Envelope Proteins / immunology; Viral Plaque Assay
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Structurally Conserved Nop56/58 N-terminal Domain Facilitates Archaeal Box C/D Ribonucleoprotein-guided Methyltransferase Activity

JOURNAL OF BIOLOGICAL CHEMISTRY, 287(23), 19418–19428.

MeSH headings : Archaeal Proteins / chemistry; Archaeal Proteins / genetics; Archaeal Proteins / metabolism; Chromosomal Proteins, Non-Histone / chemistry; Chromosomal Proteins, Non-Histone / genetics; Chromosomal Proteins, Non-Histone / metabolism; Methanococcales / chemistry; Methanococcales / genetics; Methanococcales / metabolism; Methyltransferases / chemistry; Methyltransferases / genetics; Methyltransferases / metabolism; Protein Binding; Protein Structure, Tertiary; Ribonucleoproteins / chemistry; Ribonucleoproteins / genetics; Ribonucleoproteins / metabolism
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Splice variant of the SND1 transcription factor is a dominant negative of SND1 members and their regulation in Populus trichocarpa

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(36), 14699–14704.

MeSH headings : Blotting, Western; Cloning, Molecular; DNA Primers / genetics; Dimerization; Electrophoresis, Polyacrylamide Gel; Gene Regulatory Networks / genetics; Homeostasis / physiology; Models, Biological; Plasmids / genetics; Populus / genetics; Protein Isoforms / genetics; Protein Transport; Real-Time Polymerase Chain Reaction; Transcription Factors / genetics
Source: Web Of Science
Added: August 6, 2018

2012 conference paper

Seeking novel Leishmanicidal natural products from common medicinal plants, the example of Eryngium foetidum L

Planta Medica, 78(11), 1132–1132.

By: P. Rojas-Silva, R. Graziose, A. Poulev, F. Mbeunkui, M. Grace, M. Lila, I. Raskin

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

MicroRNAs in trees

PLANT MOLECULAR BIOLOGY, 80(1), 37–53.

author keywords: MicroRNA; Woody plant; Gene regulation; Plant development; Plant stress response; Artificial microRNA
MeSH headings : Gene Expression Regulation, Plant; MicroRNAs / genetics; MicroRNAs / metabolism; Models, Genetic; Phylogeny; Plants, Genetically Modified / genetics; Plants, Genetically Modified / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; RNA, Plant / genetics; RNA, Plant / metabolism; Trees / classification; Trees / genetics; Trees / metabolism
Source: Web Of Science
Added: August 6, 2018

2012 journal article

H-1, C-13, and N-15 resonance assignments and secondary structure prediction of the full-length transition state regulator AbrB from Bacillus anthracis

BIOMOLECULAR NMR ASSIGNMENTS, 6(1), 95–98.

author keywords: AbrB; NMR; Bacillus anthracis; Transition state regulator
MeSH headings : Bacillus anthracis; Bacterial Proteins / chemistry; DNA-Binding Proteins / chemistry; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Transcription Factors / chemistry
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Open Conformation of Ezrin Bound to Phosphatidylinositol 4,5-Bisphosphate and to F-actin Revealed by Neutron Scattering

JOURNAL OF BIOLOGICAL CHEMISTRY, 287(44), 37119–37133.

By: J. Jayasundar*, J. Ju*, L. He*, D. Liu*, F. Meilleur n, J. Zhao*, D. Callaway*, Z. Bu*

MeSH headings : Actins / chemistry; Amino Acid Substitution; Cytoskeletal Proteins / chemistry; Cytoskeletal Proteins / genetics; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Neutron Diffraction; Phosphatidylinositol 4,5-Diphosphate / chemistry; Phosphoproteins / chemistry; Phosphoproteins / genetics; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Scattering, Small Angle; Sodium-Hydrogen Exchangers / chemistry; Surface Plasmon Resonance; X-Ray Diffraction
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Identification of BfmR, a Response Regulator Involved in Biofilm Development, as a Target for a 2-Aminoimidazole-Based Antibiofilm Agent

BIOCHEMISTRY, 51(49), 9776–9778.

MeSH headings : Acinetobacter baumannii / drug effects; Acinetobacter baumannii / growth & development; Bacterial Proteins / chemistry; Bacterial Proteins / physiology; Biofilms / drug effects; Imidazoles / pharmacology; Microscopy, Confocal; Models, Molecular
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Functional redundancy of the two 5-hydroxylases in monolignol biosynthesis of Populus trichocarpa: LC-MS/MS based protein quantification and metabolic flux analysis

PLANTA, 236(3), 795–808.

By: J. Wang n, C. Shuford n, Q. Li n, J. Song n, Y. Lin n, Y. Sun n, H. Chen n, C. Williams n ...

author keywords: Lignin; Syringyl lignin; Angiosperm; Kinetics; Subcellular localization
MeSH headings : Cloning, Molecular; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Hydroxylation; Kinetics; Lignin / analysis; Lignin / biosynthesis; Mixed Function Oxygenases / metabolism; Plants, Genetically Modified; Populus / metabolism; Xylem / enzymology; Yeasts / metabolism
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Comparison of Health-Relevant Flavonoids in Commonly Consumed Cranberry Products

JOURNAL OF FOOD SCIENCE, 77(8), H176–H183.

By: M. Grace*, A. Massey, F. Mbeunkui*, G. Yousef* & M. Lila*

author keywords: anthocyanins; cranberry; flavonoids; proanthocyanidins; processing
MeSH headings : Anthocyanins / analysis; Beverages; Biflavonoids / analysis; Catechin / analysis; Chromatography, High Pressure Liquid; Flavonoids / analysis; Food Handling / methods; Freeze Drying; Fruit / chemistry; Plant Extracts / analysis; Proanthocyanidins / analysis; Vaccinium macrocarpon / chemistry
Source: Web Of Science
Added: August 6, 2018

2012 journal article

A standard reaction condition and a single HPLC separation system are sufficient for estimation of monolignol biosynthetic pathway enzyme activities

PLANTA, 236(3), 879–885.

author keywords: Monolignols; Enzyme activity; Populus trichocarpa; Pinus taeda; Angiosperm; Gymnosperm
MeSH headings : Biosynthetic Pathways; Chromatography, High Pressure Liquid; Enzyme Assays; Lignin / biosynthesis; Methyltransferases / metabolism; Mixed Function Oxygenases / metabolism; Oxidoreductases / metabolism; Pinus taeda / enzymology; Plant Proteins / analysis; Plant Stems / enzymology; Populus / enzymology; Substrate Specificity; Xylem / enzymology
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Isolation and characterization of flavonols from blackcurrant by high-performance counter-current chromatography and electrospray ionization tandem mass spectrometry

JOURNAL OF SEPARATION SCIENCE, 35(13), 1682–1689.

By: F. Mbeunkui*, M. Grace*, G. Yousef* & M. Lila n

author keywords: Blackcurrant (Ribes nigrum); Flavonols; High-performance counter-current chromatography; Liquid chromatography with tandem mass spectrometry
MeSH headings : Countercurrent Distribution / methods; Flavonols / chemistry; Flavonols / isolation & purification; Plant Extracts / chemistry; Plant Extracts / isolation & purification; Ribes / chemistry; Spectrometry, Mass, Electrospray Ionization / methods
Source: Web Of Science
Added: August 6, 2018

2012 article

Functional Recognition of the Modified Human tRNA (Lys3) (UUU) Anticodon Domain by HIV's Nucleocapsid Protein and a Peptide Mimic (vol 410, pg 698, year 2011)

Journal of Molecular Biology, Vol. 420, pp. 259–259.

By: W. Graham, L. Barley-Maloney, C. Stark, A. Kaur, C. Stolarchuk, B. Sproat, G. Leszczynska, A. Malkiewicz ...

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Direct fed microbial supplementation repartitions host energy to the immune system

JOURNAL OF ANIMAL SCIENCE, 90(8), 2639–2651.

By: R. Qiu n, J. Croom n, R. Ali n, A. Ballou n, C. Smith n, C. Ashwell n, H. Hassan n, C. Chiang, M. Koci n

author keywords: broiler; direct fed microbials; energy metabolism; gene expression; probiotics; systemic immune function
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens / immunology; Chickens / metabolism; Diet / veterinary; Dietary Supplements; Energy Metabolism / immunology; Enzyme-Linked Immunosorbent Assay; Erythrocytes / immunology; Gene Expression Regulation / immunology; Gram-Positive Bacteria / physiology; Immunoglobulin A / blood; Immunoglobulin G / blood; Male; Oxygen Consumption; Sheep; Time Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018